Abstract：
BACKGROUND AND OBJECTIVES:Head and neck cancer patients often experience nutritional deterioration, which decreases their treatment tolerance and is associated with poor outcomes. We analyzed nutritional status in head and neck cancer patients before and during treatment, and its impact on clinical outcomes. METHODS AND STUDY DESIGN:Between January 2009 and April 2012, 336 head and neck cancer patients receiving radiotherapy or chemoradiotherapy were prospectively entered into the study. The Nutritional Risk Screening 2002 (NRS 2002) assessment was used to evaluate their nutritional status. RESULTS:A total of 227 patients with nasopharyngeal carcinoma and 109 patients with head and neck cancers were analyzed. The proportion of patients receiving radiotherapy or chemoradiotherapy at nutritional risk was 61.3%, with 11.9% at risk before treatment and 49.4% developing risk during treatment. In multivariate analysis, nutritional risk before treatment was associated with T stage for the two groups. Risk was significantly higher in patients receiving concurrent chemoradiotherapy during treatment for nasopharygeal carcinoma patients. The prognosis of pretreatment nutritional risk patients was worse than those becoming at risk during treatment and those without nutritional risk (3-year overall survival 62.9% vs 81.7% vs 80.6%, p=0.026; 3-year disease-free survival 64.8% vs 84.5% vs 84.4%, p=0.019). CONCLUSIONS:The incidence of nutritional risk is high in head and neck cancer patients receiving radiotherapy or chemoradiotherapy, especially during treatment. Pretreatment nutritional risk evaluated using the NRS 2002 can predict patient prognosis.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
Liu W,Gao L,Huang X,Luo J,Zhang S,Wang K,Qu Y,Xiao J,Xu G,Li Y,Yi Jdoi
10.6133/apjcn.201906_28(2).0003subject
Has Abstractpub_date
2019-01-01 00:00:00pages
223-229issue
2eissn
0964-7058issn
1440-6047journal_volume
28pub_type
杂志文章abstract：:Recent epidemiologic studies assessing tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios, and walnuts) consumption and the association with nutrient intake and diet quality are lacking. This study determined the association of tree nut consumption and nutrient intake and...
journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
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abstract：BACKGROUND:Mandatory fortification of bread with iodised salt is proposed to address the re-emergence of iodine deficiency in Australia and New Zealand. The impacts of fortification require baseline data of iodine status among vulnerable sectors of the population. OBJECTIVE:To assess the iodine status of healthy women...
journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
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abstract：:Nationwide surveys of food and nutrient intake in China have revealed geographical variation between urban and rural areas. This study developed a semi-quantitative food frequency questionnaire (SQFFQ) for cancer risk assessment suitable for both urban and rural populations by conducting a survey of food intake in Cho...
journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
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更新日期：2003-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.042017.16
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.072017.03
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2016.25.2.09
更新日期：2016-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2006-01-01 00:00:00
abstract：:Hypertension, an important risk factor for coronary heart disease (CHD), is often associated with certain dietary habits which can either adversely affect or decrease blood pressure. Several Western studies have documented the role of diet, especially excess energy, both quality and quantity of fat and salt, in the ae...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.1999.00092.x
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
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journal_title：Asia Pacific journal of clinical nutrition
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doi：10.6133/apjcn.2016.25.1.07
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
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journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:Any attempt to optimize a plant-based diet necessitates an identification of the features of the diet which confer benefit as well as any which may be associated with detrimental effects. The former task is more difficult than might be assumed as there is no doubt that some of the apparent health benefits observed amo...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2000.00180.x
更新日期：2000-09-01 00:00:00
abstract：:Inulin-based prebiotics are non-digestible polysaccharides that influence the composition of the gut microbiota in infants and children, notably eliciting a bifidogenic effect with high short chain fatty acid levels. Inulin, a generic term that comprises β-(2,1)-linked linear fructans, is typically isolated from the c...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.6133/apjcn.092016.02
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abstract：:This paper will present the socioeconomic profile and nutritional status of children aged 1-6 years in the rubber smallholdings of Peninsula Malaysia. A total of 323 households were involved in this study. The sociodemographic data were obtained through interviews with heads of households using a set of questionnaires...
journal_title：Asia Pacific journal of clinical nutrition
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doi：10.1046/j.1440-6047.2002.00275.x
更新日期：2002-01-01 00:00:00
