Abstract：
:Increased plasma homocysteine (Hcy) is a significant and independent risk factor for cardiovascular disease. It can cause multi-disease manifestations such as smooth muscle proliferation, premature occlusive vascular disease, progressive arterial stenosis, haemostatic changes, placental vasculopathy, spontaneous early abortion, birth defects, impaired cognitive function and dementia. This review paper summarizes the role of elevated Hcy levels in cardiovascular and other diseases and the molecular mechanisms and pathophysiology involved in the deleterious manifestations of hyperhomocysteinemia. We have collected data from MEDLINE, Current Contents and scientific journals, which included 112 publications from 1932 to 2007. Cardiovascular pathophysiology in hyperhomocysteinemia is a complicated process, possibly due to direct toxicity of Hcy on tissues, low S-adenosylmethionine, high S-adenosylhomocysteine or thrombotic events triggered by stimulation of procoagulant factors and suppression of anticoagulant factors and platelet activation, thereby enhancing oxidative stress, smooth muscle cell proliferation, formation of reactive oxygen species, hypomethylation, induction of unfolded protein responses and extracellular matrix modification. The mechanisms involved in the increased risk of cardiovascular disease still remains a mystery in many respects, and more studies are needed to elucidate this association.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
Huang T,Yuan G,Zhang Z,Zou Z,Li Dsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
8-16issue
1eissn
0964-7058issn
1440-6047journal_volume
17pub_type
杂志文章,评审abstract：:Australia New Zealand Food Authority (ANZFA) is a bi-national government agency forming a partnership between all of Australia's States and Territories and the New Zealand government. Australia New Zealand Food Authority employs scientific, legal policy, communication and administrative staff in our Australia and New ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2002.00002.x
更新日期：2002-01-01 00:00:00
abstract：:The centre of origin of the oil palm is the tropical rain forest region of West Africa. It is considered to be the 200-300 kilometre wide coastal belt between Liberia and Mayumbe. The oil palm tree has remained the 'tree of life' of Yoruba land as well as of other parts of southern West Africa to which it is indigenou...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：:The effectiveness of soy isoflavones to prevent bone loss in postmenopausal women is controversial. While consumption of soy in Vietnam is very high, we recently reported a prevalence of osteoporosis comparable to that of many Western populations. In the present study, we analyzed the isoflavone content of soy drink p...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:The World Health Organization reported that inappropriate feeding in children is responsible for one-third of the cases of malnutrition. This cross-sectional study aimed to determine the prevalence of malnutrition and identify the relationship between feeding practices and malnutrition in children below 5 years, in 7 ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:The aim of this study was to compare mean blood pressure (BP), anthropometric and body compositional measurements in three Chinese communities and to examine relationships between BP and body composition in these communities. A total of 935 adult (aged >= 25 years) men and women were randomly sampled from three commun...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:A micro level study on the haemoglobin status of 127 Munda (a tribe) and 174 Poundrakshatriya (Pod) (caste) women were conducted in the peri-urban area of Kolkata City, India. The two ethnic groups were selected in order to find out whether populations residing in the same habitat, with similar medical and health care...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Urbanisation runs in parallel with economic growth. Urban areas are characterised by income inequality between population groups. Because of inequality in socioeconomic situation, Indonesian urban areas are confronted with problems of undernutrition and overnutrition. Selected studies conducted by the SEAMEO-TROPMED R...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The purpose of our study was to estimate the national prevalence of metabolic syndrome, its individual components and its changes in the past decade. METHODS AND STUDY DESIGN:Two national-representative cross-sectional surveys: the China National Nutrition and Health Survey 2002 (CNNHS 2002) ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.201909_28(3).0023
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The association between tea consumption and type 2 diabetes risk remains inconsistent in Asian populations. This case-control study investigated the association between habitual tea consumption and the risk of type 2 diabetes among Vietnamese adults. METHODS AND STUDY DESIGN:A hospital-based ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.072017.08
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The quality of meta-analyses (MAs) on nutrition intervention in mainland China remains uninvestigated. To assess the quality of the evidence regarding nutrition intervention in mainland China, we used vitamin intervention as an example to assess the overall methodological and reporting qualiti...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.052017.02
更新日期：2018-01-01 00:00:00
abstract：:This paper reports on the presence of dual burden households in Orang Asli (OA, indigenous people) communities and its associated factors. A total of 182 OA households in two districts in Selangor with the required criteria (182 non-pregnant women of child bearing age and 284 children aged 2-9 years old) participated ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Notable inter-individual differences in cholesterol-lowering effects following oatmeal consumption have been previously reported. Genetic variations may among the reasons for the heterogeneous response to lipid modulations. And to determine whether SNP of cytochrome P450 family 7 subfamily A m...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.202007_29(2).0025
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:To assess stunting and zinc deficiency among primary school children in north rural area of Jiangsu Province with low soil zinc concentrations, eastern part of China. METHODS:Two data collection rounds were conducted. In the first data collection round, 2268 primary school children aged 6-9 years were includ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Myanmar has a policy of promoting food and nutrition security and, at the national level, food production is more than that required to meet the country's needs. Nevertheless, food and nutrition surveillance has revealed that malnutrition still exists in the country, despite economic growth and national food self-suff...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2001.0100s1s34.x
更新日期：2001-01-01 00:00:00
abstract：:Gestational diabetes mellitus (GDM) is a new epidemic among Australian women, especially those with Asian backgrounds. The 1998 Australia National Diabetes Strategy and Implementation Plan recognises GDM as an independent glucose metabolic disorder affecting sub-groups of Australians. Gestational diabetes mellitus is ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.1999.00072.x
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Early enteral nutrition (EEN) is better than total parenteral nutrition (TPN) for many reasons. Our aim was to determine the safety and feasibility of EEN using a jejunum feeding tube in the duodenum or jejunum for congenital obstruction in neonates post-operatively. METHODS:This was a retrospective review ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2015.24.1.08
更新日期：2015-01-01 00:00:00
abstract：:Nutrition screening is a process used to quickly identify those who may be at risk of malnutrition so that a full nutrition assessment and appropriate nutrition intervention can be provided. While many nutrition screening tools have been developed, few have been evaluated for use in older adults in the community setti...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:The combination of immunodeficiency, inflammatory process and nutritional status that is characteristic of infective and food-borne illness is more evident in chronic diet- and environment-influenced chronic diseases such as diabetes, obesity, cardiovascular disease, cancer, arthritis and neuro-degeneration diseases. ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Patients undergoing chemotherapy often develop distressing adverse effects such as oral mucositis and diarrhea. Nutritional support with elemental diet is effective against various gastrointestinal complications and may exert protective effects against adverse effects induced by chemotherapy. ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.112015.03
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to investigate the association between the level of weight-related stigmatizing experiences and binge eating in overweight adults in southern Taiwan. METHODS:This study design was a cross-sectional questionnaire survey with convenience sample. A total of 141 questionnaires were ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2015.24.1.05
更新日期：2015-01-01 00:00:00
abstract：:Our aim has been to construct a portable prototype instrument for measuring the whole body composition in vivo of growing lambs in terms of fat. protein and water by determining the mass of carbon, nitrogen and oxygen present. A small and compact sealed tube neutron generator which has the capability of exploiting the...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:To evaluate how prenatal exposure to antioxidant vitamins and heavy metals affects subsequent development. Maternal serum and cord serum levels of antioxidant vitamins (A, E, and C) were determined. Full-state, performance, and verbal intelligence quotients (FSIQ, PIQ, and VIQ, respectively) of 97 children were assess...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2015.24.4.25
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Poor sleep quality is prevalent among hemodialysis (HD) patients and leads to adverse health outcomes. This study investigated the association of nutritional parameters with sleep quality among Malaysian HD patients. METHODS AND STUDY DESIGN:A cross-sectional study was conducted among 184 Mal...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.201906_28(2).0023
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:There is very limited published data on Tibetan dietary patterns and its association with nutrient intakes and socioeconomic factors. The aim of this study was to identify and describe the dietary patterns and the associations with nutrient intakes in rural Tibetan pregnant, lactating mothers....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.012016.13
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to investigate (1) the hydrocolloid properties of grass jelly on reducing glycaemic response, (2) the impact of phenolic compounds in Mesona chinensis L. on glycaemic response. METHODS AND STUDY DESIGN:A total of 15 healthy Chinese men were recruited to this study. O...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.042017.16
更新日期：2018-01-01 00:00:00
abstract：:While improvement in agricultural technology had enabled the production of abundant food, it has thus far failed to eliminate hunger. Malnutrition is expected to reach an all time high. Evidences have suggested that animal based diet has put immense pressure on the already fragile food system, contributing to problems...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Eating habits established during childhood affect health in later life. The United Arab Emirates (UAE) has a high prevalence of obesity in adolescents and adults; however, data on the health of preschool children are scarce. This study assessed the weight status and dietary habits of Emirati a...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.201811_27(6).0018
更新日期：2018-01-01 00:00:00
abstract：:In this study an attempt has been made to know the food consumption and dietary intake of Sugalis, the largest tribal population of Andhra Pradesh, India. The sample consisted of 492 males and 474 females (drawn from 200 families) in the age group of 1-60 years. The 24-h recall diet survey revealed that the mean consu...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2000.00128.x
更新日期：2000-03-01 00:00:00
abstract：:A two-stage random telephone/mail survey was conducted during the last quarter of 1998 among Adelaide residents to determine consumers' use of soy bread and other soy products and their health expectations of soy products. One in five (21%) of 1477 telephone subscribers usually consumed soy bread and related soy produ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2002.00284.x
更新日期：2002-01-01 00:00:00
abstract：:Asian populations including Koreans are assumed to have a higher isoflavone intake due to the higher consumption of soybean. However, it is difficult to estimate isoflavone intake because there is no isoflavone database in Korea. In this study, an isoflavone database was established with systematic review. Literature ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
