Abstract:
BACKGROUND AND OBJECTIVES:Nutrition and inflammation play a crucial role in the development of cancer. The prognostic value of the prognostic nutritional index (PNI) has been confirmed in some types of human cancers. This study analyzed the prognostic significance of the preoperative PNI in patients with stage III gastric cancer after curative surgery. METHODS AND STUDY DESIGN:In this retrospective study, we enrolled 274 patients who underwent curative operation for stage III gastric cancer. The correlation between the preoperative PNI and overall survival (OS) was analyzed using Kaplan-Meier curves and multivariate Cox regression analyses. RESULTS:The patients with a high PNI had a significantly higher median OS than did those with a low PNI (46.8 months vs 24.1 months, p=0.01). In the subgroup analysis, the survival benefit of the PNI was limited to the patients with poorly differentiated gastric cancer (high PNI, 46.8 months; low PNI, 21.8 months, p=0.004) and was not observed in those with well and moderately differentiated cancer (high PNI, 30.3 months; low PNI, 26.7 months, p=0.30). In the multivariate analysis, the PNI was an independent prognostic factor for OS. CONCLUSIONS:The PNI can be used as an independent prognostic biomarker for operable advanced gastric cancer.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
Wang HX,Wang CC,Yang W,Gao LL,Yu SQdoi
10.6133/apjcn.072017.03subject
Has Abstractpub_date
2018-01-01 00:00:00pages
540-545issue
3eissn
0964-7058issn
1440-6047journal_volume
27pub_type
杂志文章abstract::A survey was conducted to monitor the current status of iodine deficiency disorders in children aged 6-12 years and women aged 15-44 years in Bangladesh as measured by goitre prevalence and urinary iodine excretion. Conducted between September 2004 and March 2005, the survey followed a stratified multistage cluster sa...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
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abstract:BACKGROUND/AIM:Nutritional states of Japanese patients with liver cirrhosis have recently shown great diversity, some show protein energy malnutrition and others excessive nutrition and obesity. For there to be adequate guidance regarding dietary treatment, it is important that a patient's current nutritional state be ...
journal_title:Asia Pacific journal of clinical nutrition
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 临床试验,杂志文章
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
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journal_title:Asia Pacific journal of clinical nutrition
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
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更新日期:1995-12-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
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doi:10.1046/j.1440-6047.11.supp3.5.x
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.062017.s2
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
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更新日期:1992-09-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
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journal_title:Asia Pacific journal of clinical nutrition
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doi:
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.092015.17
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.092015.36
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
abstract::Iodine is an essential micronutrient. The human requirement of iodine is 150 mcg/ day. About 90% of this comes from food while 10% from the water. The most commonly used method of prophylaxis against iodine deficiency is via fortification of salt with iodine. At the beneficiary level iodised salt containing 15ppm of i...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.052017.02
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1111/j.1440-6047.2001.00234.x
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
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journal_title:Asia Pacific journal of clinical nutrition
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journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2008-01-01 00:00:00