Abstract:
:Inulin-based prebiotics are non-digestible polysaccharides that influence the composition of the gut microbiota in infants and children, notably eliciting a bifidogenic effect with high short chain fatty acid levels. Inulin, a generic term that comprises β-(2,1)-linked linear fructans, is typically isolated from the chicory plant root, and derivatives such as oligofructose and long chain inulin appear to have different physiological properties. The first 1000 days of a child's life are increasingly recognized as a critical timeframe for health also into adulthood, whereby nutrition plays a key role. There is an ever increasing association between nutrition and gut microbiota composition and development, with life health status of an individual. This review summarizes the latest knowledge in the infant gut microbiota from preterms to healthy newborns, as well as in malnourished children in developing countries. The impact of inulin or mixtures thereof on infants, toddlers and young children with respect to intestinal function and immunity in general, is reviewed. Possible benefits of prebiotics to support the gut microbiome of malnourished infants and children, especially those with infections in the developing world, are considered, as well as for the pregnant mothers health. Importantly, novel insights in metabolic programming are covered, which are being increasing recognized for remarkable impact on long term offspring health, and eventual potential beneficial role of prebiotic inulins. Overall increasing findings prompt the potential for gut microbiota-based therapy to support health or prevent the development of certain diseases from conception to adulthood where inulin prebiotics may play a role. :菊粉益生元是一类非消化性多糖,能够影响婴幼儿肠道中微生态的构成,尤其 是增强双岐杆菌转化产生短链脂肪酸的作用。菊粉是一个通用的术语,包括β- (2,1)线性果聚糖(主要从菊苣植物根中分离所得)及其衍生品如低聚果糖和长 链菊粉,尽管各自具有不同的生理功能。婴儿出生后第一个1000 天被认为是影 响健康的一个关键期,甚至关系到成年期的健康,其中营养是关键因素之一。 在此关键期间营养和肠道微生物群组成之间的联系不断增强和发展,从而影响 个体的生命健康。本文总结了对健康新生儿和早产婴儿肠道微生态进行研究的 结果,以及在发展中国家对营养不良患儿进行观察的最新进展。这些研究内容 包括菊粉或其混合物对婴幼儿和较大年龄儿童的肠道功能和免疫力产生的影 响。这些研究结果显示,益生元可以支持营养不良患儿肠道中的有益微生物生 长从而抑制感染,因此特别有益于发展中国家的儿童和孕妇的健康。本文提出 了有关菊粉益生元在肠道微生态代谢编程方面的重要作用,明确了益生元对儿 童长期健康的潜在有益作用。上述研究进展为利用益生元对某些疾病进行肠道 微生态疗法治疗和预防的可能性提供了证据。.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
Firmansyah A,Chongviriyaphan N,Dillon DH,Khan NC,Morita T,Tontisirin K,Tuyen LD,Wang W,Bindels J,Deurenberg P,Ong S,Hautvast J,Meyer D,Vaughan EEdoi
10.6133/apjcn.092016.02subject
Has Abstractpub_date
2016-12-01 00:00:00pages
652-675issue
4eissn
0964-7058issn
1440-6047journal_volume
25pub_type
杂志文章,评审abstract:BACKGROUND AND OBJECTIVES:For delivery of parenteral nutrition (PN), long-term central access is often required in infants with intestinal failure (IF). Compared to central venous catheters (CVCs), peripherally inserted central catheters (PICCs) are less invasive, as they are smaller, and they can even be placed withou...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.201811_27(6).0008
更新日期:2018-01-01 00:00:00
abstract::A micro level study on the haemoglobin status of 127 Munda (a tribe) and 174 Poundrakshatriya (Pod) (caste) women were conducted in the peri-urban area of Kolkata City, India. The two ethnic groups were selected in order to find out whether populations residing in the same habitat, with similar medical and health care...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::This is a follow-up study to an investigation on the prevalence of malnutrition and micronutrient deficiencies among Vietnamese primary schoolchildren. A total of 454 children aged 7 to 8 years attending three primary schools in the Northern delta province of Vietnam were either provided with regular milk, milk fortif...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Zinc nutriture was assessed in 6500 adults aged 35-64 years old in 65 mostly rural counties (two communes per county) in China on the basis of plasma zinc levels and dietary zinc intakes. In addition, the use of plasma albumin and red blood cell superoxide dismutase (SOD) for assessing zinc nutritional status was eval...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Serum vitamin D influences cellular immunity against Mycobacterium tuberculosis, particularly in under-five children. Vitamin D insufficiency and deficiency as well as tuberculosis (TB) are highly prevalent in Indonesia. This study described the association of serum vitamin D in the incidence o...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.062017.s2
更新日期:2017-06-01 00:00:00
abstract::To investigate the relationship between dietary intake of minerals and the risk of chronic obstructive pulmonary disease (COPD), a case-control study was conducted in central Japan. A total of 278 referred patients (244 men and 34 women) aged 50-75 years with COPD diagnosed within the past four years and 340 community...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::The socio-economic status in Vietnam has developed during the past decades. People become busier for work, and thus they do not have enough time to prepare meal for their children. The school meal program, organized by Department of Education, was first implemented at a kindergarten in 1977, which has been extended to...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00
abstract::Three grades of olive oil and ten vegetable cooking oils were analysed for their phenolic content. It was hypothesised that as olive oil passed through the chemical extraction process, polyphenols would also be removed, thus reducing the antioxidant properties of olive oil. Other commonly used edible vegetable oils we...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::A study was carried out on eight to 11 year old schoolgirls to assess the prevalence of iron deficiency anemia (IDA) and to study the impact of iron supplementation on the biochemical indices of iron status. The children were characterized iron deficient anemic if their serum ferritin levels (SF) were <= 12 ng/ml and ...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::Scientific and technological developments in the agricultural sectors in the recent past has resulted in increased food production and at the same time led to certain public health concerns. Unseasonal rains at the time of harvest and improper post harvest technology often results in agricultural commodities being con...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The consumption of unhealthy snack and beverages can lead to childhood obesity, which has become a major concern globally. Television food advertisements may influence children's snack and beverages preferences. This article aims to explore children's snack and beverage consumption habits; exa...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.012017.04
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The association between skeletal muscle status and gastric cancer (GC) prognosis remains unclear. Here, we investigated the impact of the skeletal muscle index (SMI) on overall survival (OS) in GC patients after radical gastrectomy. METHODS AND STUDY DESIGN:We divided 178 patients into four g...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.201909_28(3).0003
更新日期:2019-01-01 00:00:00
abstract::The relationship between malnutrition, goitre and thyroid hormones was studied among Aborigines and Malays in Ulu Langat, Malaysia. Fifty Aborigines aged >=7years were selected randomly for anthropometric, clinical and hormonal assessment. Fifty Malays of similar age from the nearby Malay village were chosen as contro...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:Universal salt iodization (USI) was introduced in China in 1995, but whether the iodine status is optimal is questionable. This study was conducted to assess the iodine nutrition among Zhejiang population in coastal regions in China. METHODS:A cross-sectional survey for iodine nutritional status was conduct...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.2015.24.2.08
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Iron homeostasis abnormalities are associated with insulin resistance (IR), but studies on such associations in children and adolescents are limited and have contrasting results. The purpose of this study was to determine the associations between indicators of iron status and IR, and assesse i...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.201912_28(4).0019
更新日期:2019-01-01 00:00:00
abstract::The Asia-Pacific region is undergoing a major change in both food and health patterns, with a connection between the two more than likely. Evidence for certain traditional Asia-Pacific foods as protective agents against chronic non-communicable disease and cardiovascular disease (CVD), in particular, is growing at a t...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1111/j.1440-6047.2001.00234.x
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To study the associations between nutrient intake, dairy intake and socioeconomic variables. METHODS AND STUDY DESIGN:Food consumption data using 24 h recall were collected in 3600 children, aged 0.5 to 12 years old in addition to frequency of dairy use and anthropometric and sociodemographic...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.2016.25.2.09
更新日期:2016-01-01 00:00:00
abstract::The main aim of this study was to validate the use of the Caucasian-based knee height equations for predicting stature of Chinese elderly subjects and to compare the predicted height to those estimated by equations derived from elderly subjects of Chinese origin. The study was performed by a survey by measurement of c...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.1046/j.1440-6047.2000.00158.x
更新日期:2000-12-01 00:00:00
abstract::People of Indian origin develop type 2 diabetes at a relatively young age and low body mass index compared to people of other racial groups, possibly because of preferential accumulation of abdominal fat. We examined the relationship between abdominal fat and body mass index (BMI) in healthy premenopausal women of dif...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Human milk has nutritional, protective, and developmental advantages for premature infants. However, proteomic information of low abundant protein of donor milk is insufficient. The purpose of this study is to analyze and compare the proteome of low abundant protein of donor milk obtained at d...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.032017.16
更新日期:2018-01-01 00:00:00
abstract::This paper reports on the presence of dual burden households in Orang Asli (OA, indigenous people) communities and its associated factors. A total of 182 OA households in two districts in Selangor with the required criteria (182 non-pregnant women of child bearing age and 284 children aged 2-9 years old) participated ...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::The aim of the study was to evaluate whether supplementation of milk-formulas with prebiotic fructo-oligosaccharides or a probiotic, Lactobacillus johnsonii La1 (La1), could modulate the composition of the fecal microbiota of formula-fed infants, compared to breastfed (BF) infants. Ninety infants close to 4 months of ...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2006-01-01 00:00:00
abstract::A computer system, called SERVE-NZ Nutririon Management System, for use in diabetes management, addresses the problem of concurrently controlling postprandial glycaemic response and nutrient intake in meals containing a number of foods, is described. It converts the weight and relative glycaemic potency of each food t...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.1046/j.1440-6047.2000.00146.x
更新日期:2000-06-01 00:00:00
abstract::This is a review article telling a 50-years old story about the studies on selenium deficiency and Keshan disease in China, an endemic heart disease with high case-fatality, as an example of translational research. Extensive cross-sectional epidemiological studies showed that low selenium concentrations in cereal grai...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00
abstract::Malnutrition in hospitals often goes unrecognized. At present, no nutrition screening tool provides satisfactory re-sults in identifying nutritional risk. Most tools depend on weight and height as criteria for diagnosing malnutrition. Weight is not recorded in many patients and some tools are time-consuming. An inclus...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.2013.22.4.06
更新日期:2013-01-01 00:00:00
abstract::In 2000, India revoked the ban on production and sale of non-iodised salt. We conducted a study in the north 24 Parganas district in the state of West Bengal to assess the prevalence of goitre, status of urinary iodine excretion (UIE) level and to estimate iodine content of salts at the household level. We surveyed 36...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Data suggest that genetic factors are associated with BMI. The fat mass and obesity- associated (FTO) gene modulates adipogenesis through alternative splicing and m6A demethylation. Individuals with FTO rs9939609 gene polymorphism have a preference for energy-dense foods. This study investigat...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.201903_28(1).0024
更新日期:2019-01-01 00:00:00
abstract::The purpose of this study was to develop and cross-validate anthropometric equations for the estimation of appendicular skeletal muscle mass (ASM) in Chinese adults. A total of 763 adults aged 18-69 years (345 men and 418 women) were recruited from residents living in four regions (Jinan, Guangzhou, Xi'an and Chengdu)...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::Dietary assessment provides information on what people eat and how well they eat. Recent trends in changes of health problems related to diet require more accurate evaluation of diet since now we know that both under- and over-consumption of nutrients can bring health risks. Non-traditional new components have been id...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract::We aimed to prospectively examine the association between the combined effects of obesogenic behaviors on quality of life (QOL) in adolescents. Of 2353 Sydney schoolchildren surveyed (median age 12.7 years), 1,213 were re-examined 5 years later at age 17-18. Children completed activity and food-frequency questionnaire...
journal_title:Asia Pacific journal of clinical nutrition
pub_type: 杂志文章
doi:10.6133/apjcn.2014.23.1.13
更新日期:2014-01-01 00:00:00