Skin signs of systemic disease. When the problem is more than skin-deep.

Abstract:

:The cutaneous manifestations of systemic diseases are diverse. In some cases, they are the first signs of an underlying disorder, such as Cowden's disease, dermatomyositis, and Lyme disease. Sister Mary Joseph's nodule (metastatic involvement of the umbilicus) is an ominous sign of internal malignant disease. Drug-induced skin necrosis may result from therapy with coumarin (Coumadin, Panwarfin, Sofarin) or heparin.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Holmes CE,Massa MC

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

93-6, 99-102

issue

8

eissn

0032-5481

issn

1941-9260

journal_volume

96

pub_type

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