Baking soda misuse as a home remedy: case experience of the California Poison Control System.

Abstract:

WHAT IS KNOWN AND OBJECTIVE:Baking soda is a common household product promoted by the manufacturer as an antacid. It contains sodium bicarbonate and has the potential for significant toxicity when ingested in excessive amounts. Characterizing the patterns and outcomes from the misuse of baking soda as a home remedy can guide the clinical assessment and preventative counselling of patients at risk for use of this product. METHODS:We conducted a retrospective review of all symptomatic cases involving ingestion and misuse of a baking soda powder product that were reported to the California Poison Control System between the years 2000 and 2012. RESULTS AND DISCUSSION:Of the 192 cases we identified, 55·8% were female, ages ranged 2 months to 79 years, and the most common reasons for misuse included antacid (60·4%), 'beat a urine drug test' (11·5%) and treat a UTI (4·7%). Most cases (55·2%) had significant symptoms warranting a medical evaluation, whereas 12 patients required hospital admission developed either electrolyte imbalances, metabolic alkalosis or respiratory depression. WHAT IS NEW AND CONCLUSION:Misuse of baking soda can result in serious electrolyte and acid/base imbalances. Patients at highest risk of toxicity may include those who chronically use an antacid, those who use the method to 'beat' urine drug screens, pregnant women and young children. Self-treatment with baking soda as a home remedy may also mask or delay medical care thereby complicating or exacerbating an existing medical problem. We suggest that healthcare providers counsel high-risk patients about the potential complications of misuse of baking soda as a home remedy.

journal_name

J Clin Pharm Ther

authors

Al-Abri SA,Kearney T

doi

10.1111/jcpt.12113

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

73-7

issue

1

eissn

0269-4727

issn

1365-2710

journal_volume

39

pub_type

杂志文章
  • Decreased INR after acenocoumarol, ombitasvir/paritaprevir/ritonavir and dasabuvir co-administration.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Limited data are available on co-administration of acenocoumarol with direct-acting antiviral agents for chronic hepatitis C virus infection. CASE SUMMARY:We report a case of a patient who required a significant increase in acenocoumarol weekly dose probably due to an interaction with ombit...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.12403

    authors: de Lorenzo-Pinto A,Giménez-Manzorro Á,Rodríguez-González CG,Ahumada-Jiménez A,Herranz-Alonso A,Marzal-Alfaro MB,Sanjurjo-Sáez M

    更新日期:2016-08-01 00:00:00

  • Comparison of antibiotic susceptibility in viridans group streptococci in low and high antibiotic-prescribing General Practices.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Antibiotic resistance has become a global public health issue. Most antibiotics are prescribed in the community, although there is less stewardship of such agents in the community compared to secondary and tertiary care. Few studies have attempted to examine the prescribing practices in Gene...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12245

    authors: Goldsmith CE,Hara Y,Sato T,Nakajima T,Nakanishi S,Mason C,Moore JE,Matsuda M,Coulter WA

    更新日期:2015-04-01 00:00:00

  • Stability of mupirocin ointment (Bactroban) admixed with other proprietary dermatological products.

    abstract::This study involved the mixing of 1:1 combinations of Bactroban (mupirocin) Ointment 2% with various cream, lotion, ointment, gel, solution and liquid soap formulations with storage at 37 degrees C for 60 days. The mixtures were assayed for mupirocin content at 0, 15, 30, 45 and 60 days using a high-pressure liquid ch...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1992.tb01290.x

    authors: Jagota NK,Stewart JT,Warren FW,John PM

    更新日期:1992-06-01 00:00:00

  • Particulate contamination of lyophilized amphotericin B preparation during reconstitution process.

    abstract:OBJECTIVE:To investigate the effect of the reconstitution methods for the commercial amphotericin B preparation with respect to particulate contamination. METHODS:The particle counts in amphotericin B solutions reconstituted according to three different methods and amphotericin B fluids made with intravenous fluids af...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.2001.00328.x

    authors: Sendo T,Hirakawa M,Makino K,Nakashima K,Kataoka Y,Oishi R

    更新日期:2001-04-01 00:00:00

  • Ceftriaxone-associated renal toxicity in adults: a case report and recommendations for the management of such cases.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Ceftriaxone is a third-generation cephalosporin with broad-spectrum antibacterial activity. Ceftriaxone-associated urolithiasis and post-renal acute renal failure (PARF) in adults is exceedingly rare and perhaps underappreciated. We report one such case to increase appreciation of this risk ...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.12358

    authors: Shen-Hua W,Fan-Yi M,Qing-Ling Z,Li-Na Z,Li-Jun M

    更新日期:2016-06-01 00:00:00

  • Association of ABCB1 C3435T polymorphism with phenobarbital resistance in Thai patients with epilepsy.

    abstract:WHAT IS KNOWN AND OBJECTIVE:One-third of patients with epilepsy are resistant to anti-epileptic drugs (AEDs). Drug-resistant epilepsy is believed to be multifactorial involving both genetic and non-genetic factors. Genetic variations in the ABCB1 gene encoding the drug efflux transporter, p-glycoprotein (p-gp), may inf...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12263

    authors: Keangpraphun T,Towanabut S,Chinvarun Y,Kijsanayotin P

    更新日期:2015-06-01 00:00:00

  • A study of patients' self-interpretation of prescription instructions.

    abstract::This study examined out-patients' interpretation of prescription instructions at a community hospital. The results showed a wide range of misinterpretation with respect to drug name, dose schedule, and auxiliary labels. Age level, education and financial status emerged as the most significant variables associated with...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1992.tb01280.x

    authors: Sarriff A,Aziz NA,Hassan Y,Ibrahim P,Darwis Y

    更新日期:1992-04-01 00:00:00

  • Comparison of pharmacodynamic effects of ticagrelor vs prasugrel in type 2 diabetes mellitus patients with coronary heart disease.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Patients with type 2 diabetes mellitus (T2DM) are at higher risk of thrombotic complications. Studies have indicated that patients with T2DM have impaired clopidogrel-induced antiplatelet effect. Ticagrelor and prasugrel are two latest generation P2Y12 inhibitors with advantageous platelet i...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jcpt.12651

    authors: Shang LL,Guo DD,Zhao HY,Quan AJ,Cao PG

    更新日期:2018-06-01 00:00:00

  • Functional allele and genotype frequencies of CYP1A2, CYP2B6 and iNOS among mainland Chinese Tibetan, Mongolian, Uygur and Han populations.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Cytochrome P450 1A2 (CYP1A2), CYP2B6 and inducible nitric oxide synthase (iNOS) are involved in the metabolism and action of many important therapeutic drugs, and genetic variants have been associated with interethnic differences in response to treatment, including chemotherapy. METHODS:Eig...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12351

    authors: Qi GZ,Zhang ZY,Wang X,Yin SJ,Lou YQ,Zhang GL

    更新日期:2016-02-01 00:00:00

  • Rapid-onset antidepressant action of ketamine: potential revolution in understanding and future pharmacologic treatment of depression.

    abstract:WHAT IS KNOWN AND OBJECTIVE:The current pharmacotherapeutic treatment of major depressive disorder (MDD) generally takes weeks to be effective. As the molecular action of these drugs is immediate, the mechanistic basis for this lag is unclear. A drug that has a more rapid onset of action would be a major therapeutic ad...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12238

    authors: Drewniany E,Han J,Hancock C,Jones RL,Lim J,Nemat Gorgani N,Sperry JK 3rd,Yu HJ,Raffa RB

    更新日期:2015-04-01 00:00:00

  • Decitabine prior to salvaged cord blood transplantation for acute myeloid leukaemia/myelodysplastic syndrome not in remission.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Many refractory/relapsed haematological malignancies, in non-remission state, still have poor prognosis even after allogeneic haematopoietic stem cell transplantation. Recently, decitabine or umbilical cord blood transplantation (UCBT) seemed to be effective in these patients. However, few s...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.13231

    authors: Yao W,Chu X,Fang X,Zhu X,Tang B,Wan X,Geng L,Tong J,Song K,Zhang X,Qiang P,Sun G,Liu H,Sun Z

    更新日期:2020-12-01 00:00:00

  • CYP2D6 phenotypes among Malays in Malaysia.

    abstract:BACKGROUND:Although they originated from China, Malays have undergone a lot of intermarriages. A study suggested that CYP2D6 poor metabolism (PM) phenotype was more common in Malays compared to Chinese. CYP2D6 is highly polymorphic and is involved in the metabolism of many drugs and has been implicated in some environm...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.2000.00304.x

    authors: Ismail R,Hussein A,Teh LK,Nizam Isa M

    更新日期:2000-10-01 00:00:00

  • Omission of aspirin in patients following coronary artery bypass graft surgery.

    abstract::Graft patency is a major factor contributing to the long-term results of coronary artery bypass graft (CABG) surgery. The systematic overview of the Antiplatelet Trialists' Collaboration provides unequivocal evidence that antiplatelet therapy reduces by nearly one-half the odds of coronary graft occlusion following CA...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1994.tb00697.x

    authors: Galea J,Manché A,Goiti JJ,Locke TJ,Wilkinson GA,Smith GH

    更新日期:1994-12-01 00:00:00

  • Evaluation of pregabalin-induced adverse events related to falls using the FDA adverse event reporting system and Japanese Adverse Drug Event Report databases.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Pregabalin is used for neuropathic and postherpetic pain and generalized anxiety. The aim of this study was to obtain the onset profiles of adverse events (AE) related to falls (AEFs) such as "somnolence," "dizziness," "loss of consciousness" and "fall" onset and several clinical factor comb...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12790

    authors: Mukai R,Hasegawa S,Umetsu R,Nakao S,Shimada K,Uranishi H,Masuta M,Suzuki H,Nishibata Y,Nakamura M

    更新日期:2019-04-01 00:00:00

  • Evaluation of the quality of four Mexican drug products containing sodium naproxen.

    abstract:BACKGROUND:There is currently a lot of concern about the quality and therapeutic effectiveness of Mexican pharmaceutical products, and considerable price differences between alternative products containing the same active principle. OBJECTIVE:To establish whether four Mexican drug products, a high price and three lowe...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2008.00910.x

    authors: Hernández-Abad VJ,Castañeda-Hernández G,García-Jiménez S,Marroquín-Segura R,Sánchez-González E

    更新日期:2008-06-01 00:00:00

  • A phase I trial assessing the safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of single-dose Auron Misheil therapy in healthy male subjects.

    abstract:BACKGROUND AND OBJECTIVE:Auron Misheil therapy (AMT) is a combination of widely used pharmaceuticals and herbal components that has been used since the 1980s as a supportive therapy, mainly in end-stage cancer patients on a compassionate basis. This phase I study was conducted to assess the safety, tolerability, and ph...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2009.01087.x

    authors: Scheele J,Diergarten K,Drevs J,Niazi FR

    更新日期:2013-02-01 00:00:00

  • Stability of moxifloxacin injection in peritoneal dialysis solution bags (Dianeal PD1 1.36% and Dianeal PD1 3.86%).

    abstract:BACKGROUND AND OBJECTIVE:Moxifloxacin is a new fluorquinolone with broad-spectrum activity. It is suitable for treating peritonitis in peritoneal dialysis (PD) patients. The objective of this study was to test stability of moxifloxacin in PD solutions stored at different temperatures. METHODS:Dialysis solution bags we...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2006.00758.x

    authors: Fernández-Varón E,Marín P,Espuny A,Villamayor L,Escudero E,Cárceles C

    更新日期:2006-12-01 00:00:00

  • Qualitative studies on alpha-interferon-2b in prolonged continuous infusion regimes using gradient elution high-performance liquid chromatography.

    abstract::The treatment of home-based cancer patients with continuous infusion chemotherapy requires that complete courses of medication in pre-filled syringes are provided on an out-patient basis. The infusion must remain stable prior to use during refrigerated storage (up to 14 days) and during infusion from holster-worn ambu...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1988.tb00185.x

    authors: Palmer AJ,Sewell GJ,Rowland CG

    更新日期:1988-06-01 00:00:00

  • Extremely low dose of 6-mercaptopurine in a Chinese child with acute lymphoblastic leukaemia and multiple pharmacogenetic mutations.

    abstract:WHAT IS KNOWN AND OBJECTIVES:Thiopurines are cornerstone drugs in the treatment of acute lymphoblastic leukaemia (ALL), but their use can be complicated by the incidence of life-threatening leucopenia. CASE DESCRIPTION:We describe a case of a 6-year-old Chinese boy with B-ALL receiving extremely low dose of 6-mercapto...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.13255

    authors: Zhai XY,Zhou Y,Dong L,Nie AQ,Zhi LJ,Jacqz-Aigrain E,Wang TY,Wang L,Zhao W

    更新日期:2021-02-01 00:00:00

  • Advances in pharmacotherapy: treatment of hypertensive crisis.

    abstract::A hypertensive crisis can be caused by many factors. Frequently, the mechanism involved is complex and highly variable among patients. Without drug therapy, this condition is associated with very high mortality and morbidity. There are a number of oral and intravenous hypotensive agents available, which can effectivel...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2710.1994.tb00669.x

    authors: McKindley DS,Boucher BA

    更新日期:1994-06-01 00:00:00

  • Population pharmacokinetics of erlotinib in Japanese patients with advanced non-small cell lung cancer.

    abstract:WHAT IS KNOWN AND OBJECTIVE:This study aimed to elucidate the pharmacokinetics of erlotinib in Japanese patients with advanced non-small cell lung cancer (NSCLC) and to investigate the relationship between erlotinib exposure and the occurrence of interstitial lung disease (ILD)-like events. METHODS:Population pharmaco...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12232

    authors: Emoto-Yamamoto Y,Iida S,Kawanishi T,Fukuoka M

    更新日期:2015-04-01 00:00:00

  • Azacitidine-associated haemorrhagic enteritis in a case of myelodysplastic syndrome: A case report.

    abstract:WHAT IS KNOWN AND OBJECTIVE:5-Azacitidine (AZA) is an agent widely used to treat myelodysplastic syndrome (MDS). CASE DESCRIPTION:We herein report an 83-year-old woman diagnosed with MDS who was treated with AZA. She tolerated the first cycle of AZA; however, severe adverse events involving haemorrhagic enteritis with...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.13146

    authors: Hagino T,Shinomiya W,Hidai H,Umeda M,Kurimoto M,Saga R,Tsutsumi H,Shibata Y,Akiyama H,Motomura S

    更新日期:2020-08-01 00:00:00

  • Efficacy and safety of gabapentin 1800 mg treatment for post-herpetic neuralgia: a meta-analysis of randomized controlled trials.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Gabapentin has been used for the management of post-herpetic neuralgia (PHN). However, inconsistent results have been reported. This meta-analysis was performed to assess the efficacy and safety of gabapentin 1800 mg/day in PHN patients by conducting a meta-analysis. METHODS:Electronic data...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/jcpt.12167

    authors: Fan H,Yu W,Zhang Q,Cao H,Li J,Wang J,Shao Y,Hu X

    更新日期:2014-08-01 00:00:00

  • Linezolid and the risk of lactic acidosis: Data mining and analysis of the FDA Adverse Event Reporting System.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Lactic acidosis (LA) is a rare but potentially lethal side effect of linezolid (LZD). However, limited by the study population, the number of patients with LA is insufficient to summarize all the clinical characteristics and risk factors. METHODS:We evaluated the association between LZD and...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.13245

    authors: Dai Y,Wang Y,Zeng Y,Zhang C,Zhou Z,Shi D

    更新日期:2020-12-01 00:00:00

  • Evaluation of an information booklet for general practitioners with patients on home parenteral nutrition.

    abstract::An information package was developed for general practitioners (GPs) involved in the management of home parenteral nutrition (HPN) patients. The booklet covered five major sections: background information; HPN training; complications of HPN; arrangements for a particular patient; and hospital management of HPN. This s...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1988.tb00210.x

    authors: Malone M

    更新日期:1988-12-01 00:00:00

  • Investigation of urinary levels of salbutamol in asthmatic patients receiving inhaled therapy.

    abstract:AIM:Some studies have indicated that over-reliance on inhaled bronchodilator (beta 2-agonist) therapy may worsen asthma control and increase morbidity. The aim of this study was to measure urinary concentrations of salbutamol, the most commonly used bronchodilator, in a relatively large sample of asthmatic patients and...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1997.tb00005.x

    authors: Jacobson GA,Peterson GM,McLean S

    更新日期:1997-04-01 00:00:00

  • Drug utilization pattern of antiepileptic drugs and traditional Chinese medicines in a general hospital in Taiwan - a pharmaco-epidemiologic study.

    abstract:OBJECTIVE:Studies on antiepileptic drug utilization are important for the optimization of drug therapy and drug control. The present study was to evaluate the drug utilization pattern of standard antiepileptic drugs and traditional Chinese medicines (TCMs) in the treatment of different types of epilepsy in a general ho...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.2000.00271.x

    authors: Chen LC,Chen YF,Yang LL,Chou MH,Lin MF

    更新日期:2000-04-01 00:00:00

  • Application of dynamic laser scattering to the quality control of injectable drugs: polymer formation in ampicillin solution.

    abstract:OBJECTIVE:To assess the usefulness of dynamic laser scattering for monitoring the stability of ampicillin after reconstitution from commercially available vials with respect to the polymer formation and potency. METHODS:Polymer formation and the remaining potency of the reconstituted ampicillin solution were estimated...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.2002.00397.x

    authors: Sendo T,Teshima D,Makino K,Mishima K,Itoh Y,Oishi R

    更新日期:2002-04-01 00:00:00

  • QTc prolongation during antiviral therapy in two COVID-19 patients.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Acquired long QT syndrome secondary to drug-induced QT prolongation and torsades de pointes has been reported for antiviral drugs. However, no studies have reported an association between corrected QT (QTc) prolongation and antiviral therapy in patients with novel coronavirus disease (COVID-...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.13183

    authors: Zhu S,Wang J,Wang Y,Chu J,Liu Y,Chen X,Chen X

    更新日期:2020-10-01 00:00:00

  • Transition from intravenous or subcutaneous prostacyclin therapy to inhaled treprostinil in patients with pulmonary arterial hypertension: a retrospective case series.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Inhaled treprostinil represents an attractive alternative to the other available prostacyclin formulations by obviating the use of continuous infusions and its associated risks. Published evidence describing the process of transition from infusion prostacyclin therapy to inhaled treprostinil...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12170

    authors: Enderby CY,Soukup M,Al Omari M,Zeiger T,Burger C

    更新日期:2014-10-01 00:00:00