A study of patients' self-interpretation of prescription instructions.

abstract：WHAT IS KNOWN AND OBJECTIVE:Antituberculosis drug-induced liver injury (ATLI) is a serious adverse drug reaction, and its pathogenic mechanism is still largely unknown. Rifampin (RIF) has been reported to cause haemolysis due to the production of drug-dependent antibodies, and haemolysis results in an increased level o...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tao B,Yang M,Chen H,Pan H,Liu W,Yi H,Tang S

更新日期：2020-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:Thiopurines are cornerstone drugs in the treatment of acute lymphoblastic leukaemia (ALL), but their use can be complicated by the incidence of life-threatening leucopenia. CASE DESCRIPTION:We describe a case of a 6-year-old Chinese boy with B-ALL receiving extremely low dose of 6-mercapto...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhai XY,Zhou Y,Dong L,Nie AQ,Zhi LJ,Jacqz-Aigrain E,Wang TY,Wang L,Zhao W

更新日期：2021-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Linezolid, a member of the oxazolidinone class of antibacterial drugs, is approved by the US Food and Drug Administration (FDA) for the treatment of vancomycin-resistant Enterococcus faecium infections, nosocomial and community-acquired pneumonia, as a part of anti tubercular regimen and com...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Singhania SVK,Shenoy S,Kapoor D

更新日期：2020-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Despite recommendations to avoid fluoroquinolones (FQs) as a first-line treatment for uncomplicated cystitis, recent data suggest that FQs remain widely prescribed. Therefore, the objectives of this study were to evaluate the appropriateness of empiric FQ use compared to nitrofurantoin for u...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Robinson TF,Barsoumian AE,Aden JK,Giancola SE

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Psoriatic arthritis is an autoimmune disease characterized by chronic inflammation of the skin and joints. Anti-TNF drugs reduce the severity of the disease in the long term. This study compares the efficacy and safety of adalimumab, etanercept, infliximab and golimumab in patients with psor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fénix-Caballero S,Alegre-del Rey EJ,Castaño-Lara R,Puigventós-Latorre F,Borrero-Rubio JM,López-Vallejo JF

更新日期：2013-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chromium is an essential mineral for carbohydrate and lipid metabolism. Results of previous systematic reviews and meta-analyses of chromium supplementation and metabolic profiles in diabetes have been inconsistent. Recently, several published trials have emerged. We conducted a systematic r...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suksomboon N,Poolsup N,Yuwanakorn A

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:A pain relief score 50% of the maximum is often used as a clinically meaningful outcome in meta-analyses of analgesic trials. This arbitrary value requires validation. OBJECTIVE:To determine the optimum pain relief score for predicting pain relief sufficient to obviate the need for analgesic remedication in...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Li Wan Po A,Petersen B

更新日期：2006-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Colchicine is an anti-inflammatory agent used primarily in treatment of gout and familial Mediterranean fever. Toxicity is uncommon, and depends on dose, hepatic or renal impairment, co-administration with P-glycoprotein or CYP3A4 inhibitors and route of administration. In patients taking p-...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Abodunde OA,LevakaVeera RR,Desai R,Nweke N,Berrou M

更新日期：2013-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Therapeutic effects of anti-VEGF agents, corticosteroids and laser therapy have been previously examined for treating macular oedema secondary to branch and central retinal vein occlusion (BRVO and CRVO). However, anti-VEGF efficacy has not been previously compared to corticosteroid or laser...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Qian T,Zhao M,Xu X

更新日期：2017-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Gabapentin has been used for the management of post-herpetic neuralgia (PHN). However, inconsistent results have been reported. This meta-analysis was performed to assess the efficacy and safety of gabapentin 1800 mg/day in PHN patients by conducting a meta-analysis. METHODS:Electronic data...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fan H,Yu W,Zhang Q,Cao H,Li J,Wang J,Shao Y,Hu X

更新日期：2014-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:To date, no case of headache has been reported with enoxaparin. We present the case of a 60-years-old man, who developed enoxaparin-induced throbbing headache and discuss the possible pharmacological mechanisms. We provide an analysis of enoxaparin-induced headache in three international da...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Brusadelli T,Carnovale C,Gentili M,Borsadoli C,Speziali A,Perrone V,Pellegrino P,Antoniazzi S,Pozzi M,Radice S,Clementi E

更新日期：2015-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chemotherapy can increase treatment-related mortality associated with future haematopoietic stem cell transplantation (HSCT) for patients with relapsed/refractory acute myeloid leukaemia (AML). There is usually insufficient time to find a suitable unrelated donor for these patients. We repor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhang C,Chen XH,Liu J,Gao L,Liu Y,Gao L,Kong PY,Zhang X

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Studies on antiepileptic drug utilization are important for the optimization of drug therapy and drug control. The present study was to evaluate the drug utilization pattern of standard antiepileptic drugs and traditional Chinese medicines (TCMs) in the treatment of different types of epilepsy in a general ho...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Chen LC,Chen YF,Yang LL,Chou MH,Lin MF

更新日期：2000-04-01 00:00:00

abstract：INTRODUCTION:Spironolactone is increasingly being used in the treatment of heart failure. However, it has been associated with cases of hyperkalaemia. The common use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin-2 receptor (AT2) antagonists in heart failure increases the risk of hyperkalaemia. OBJE...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Anton C,Cox AR,Watson RD,Ferner RE

更新日期：2003-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Ceftriaxone is a third-generation cephalosporin with broad-spectrum antibacterial activity. Ceftriaxone-associated urolithiasis and post-renal acute renal failure (PARF) in adults is exceedingly rare and perhaps underappreciated. We report one such case to increase appreciation of this risk ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Shen-Hua W,Fan-Yi M,Qing-Ling Z,Li-Na Z,Li-Jun M

更新日期：2016-06-01 00:00:00

abstract：:In many countries, including The Netherlands, little is known about the overall prescribing patterns within hospitals. While individual hospitals have some data available, these are not pooled on a regional or national level. The available data consist of dispensing data that are neither patient-linked nor diagnosis-l...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Denig P,Haaijer-Ruskamp FM,Versluis A,Wesseling H

更新日期：1991-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:This study aimed to elucidate the pharmacokinetics of erlotinib in Japanese patients with advanced non-small cell lung cancer (NSCLC) and to investigate the relationship between erlotinib exposure and the occurrence of interstitial lung disease (ILD)-like events. METHODS:Population pharmaco...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Emoto-Yamamoto Y,Iida S,Kawanishi T,Fukuoka M

更新日期：2015-04-01 00:00:00

abstract：WHAT IS KNOWN:The increased risk of cardiovascular events in diabetic patients has been related to numerous metabolic and haemoreological factors. Some of these factors appear to be particularly evident during the post-prandial phases and to be related to peak plasma glucose level. AIM:To compare the effect of additio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Derosa G,Mereu R,D'Angelo A,Salvadeo SA,Ferrari I,Fogari E,Gravina A,Palumbo I,Maffioli P,Randazzo S,Cicero AF

更新日期：2010-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Acquired long QT syndrome secondary to drug-induced QT prolongation and torsades de pointes has been reported for antiviral drugs. However, no studies have reported an association between corrected QT (QTc) prolongation and antiviral therapy in patients with novel coronavirus disease (COVID-...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhu S,Wang J,Wang Y,Chu J,Liu Y,Chen X,Chen X

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To report a case of a patient with psoriatic arthritis (PsA) receiving adalimumab, who developed an exacerbation of palmoplantaris pustulosa psoriasis. CASE SUMMARY:A 38-year-old woman diagnosed with PsA had received treatment with non-steroidal antiinflammatory drugs. Two months prior to admission, the pati...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Borrás-Blasco J,Gracia-Perez A,Nuñez-Cornejo C,Rosique-Robles JD,Mateu-Puchades A,Casterá MD,Rubio-Fabra M

更新日期：2008-06-01 00:00:00

abstract：:Isradipine is a potent dihydropyridine calcium channel blocker. It is highly selective for vascular smooth muscle, with very few negative inotropic or chronotropic effects. It may have minor depressant effects on the sinoatrial node, hence reducing the incidence of reflex tachycardia. The drug is extensively metaboliz...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Schachter M

更新日期：1991-04-01 00:00:00

abstract：:The in vitro dissolution rates of 5 and 10 mg nifedipine capsules from eight suppliers were measured in simulated gastric fluid using the rotating paddle apparatus. A total of fourteen products were tested and the performance was found to be satisfactory for all products (> 80% dissolution in 20 min). ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mehta AC,Hart-Davies S,Kay EA

更新日期：1995-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:One-third of patients with epilepsy are resistant to anti-epileptic drugs (AEDs). Drug-resistant epilepsy is believed to be multifactorial involving both genetic and non-genetic factors. Genetic variations in the ABCB1 gene encoding the drug efflux transporter, p-glycoprotein (p-gp), may inf...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Keangpraphun T,Towanabut S,Chinvarun Y,Kijsanayotin P

更新日期：2015-06-01 00:00:00

abstract：:There has been much interest recently in the delivery of proteins and peptides following the research and development of biotechnology: derived drugs and other bioactive substances. This article summarizes the use of iontophoresis to deliver proteins and peptides across the skin. This technique offers considerable pro...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Parasrampuria D,Parasrampuria J

更新日期：1991-02-01 00:00:00

abstract：:Nineteen different brands of topical creams were tested in duplicate for microbial growth. The efficacy of their preservation was assessed, when possible, by standard pharmacopoeial procedures. Microbial growth was demonstrated in cultures from all specimens. However, high counts (> 10(4) c.f.u./g) were obtained from ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Na'was T,Alkofahi A

更新日期：1994-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Demonstration of the utility of electronic medical records (EMRs) for pharmacovigilance (PV) has been highly anticipated. Analysis using appropriately selected EMRs should enable accurate estimation of adverse drug event (ADE) frequencies and thus promote appropriate regulatory actions. Stat...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Sai K,Hanatani T,Azuma Y,Segawa K,Tohkin M,Omatsu H,Makimoto H,Hirai M,Saito Y

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Auron Misheil therapy (AMT) is a combination of widely used pharmaceuticals and herbal components that has been used since the 1980s as a supportive therapy, mainly in end-stage cancer patients on a compassionate basis. This phase I study was conducted to assess the safety, tolerability, and ph...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Scheele J,Diergarten K,Drevs J,Niazi FR

更新日期：2013-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:ABT-594 is a non-opioid, non-NSAID analgesic. The objective of this work was to characterize the population pharmacokinetics of ABT-594 in subjects with neuropathic pain. METHODS:Efficacy, safety and pharmacokinetics of ABT-594 in subjects with painful diabetic polyneuropathy were evaluated...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Dutta S,Awni W

更新日期：2012-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Ticagrelor is a reversibly binding and selective P2Y12 -receptor antagonist approved for the prevention of atherothrombotic events in patients with acute coronary syndromes. As bleeding events remain a hazard with antiplatelet therapy, this study investigated the effect of the vasopressin ag...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Teng R,Mitchell PD,Butler K

更新日期：2014-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Low levels of serum triiodothyronine (T3) are a strong predictor of mortality and poor prognosis in critical care patients. Few reports, however, have focused on neurocritical patients. The application of hormone replacement therapy (HRT) in the treatment of neurocritical patients with low T...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Chen Y,Chang J,Yin R,Wen J,Ma B,Zuo W,Zhang X,Wei J

更新日期：2020-08-01 00:00:00