Abstract:
:Structural hemoglobinopathy due to carriage of Hb Camden was diagnosed in a male patient and his mother. Anomalous Hb was detected after a detailed analysis of the clinical evidence, blood smears microscopy, marrow examination, data obtained by a complex of methods to identify unstable Hb. It was defined as Hb Camden beta 131 GLN-->GLU. The carriage of this variant brings no clinical manifestations, but leads to impaired red cells morphology, decline of their life span, enhanced hemolysis. These properties are typical for mutant Hb lacking stability. Hb Camden carriage is considered as a compensatory hemolytic process.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Aseeva EA,Lutsenko IN,Pivnik AV,Spivak VA,Beliaeva LS,Kremenetskaia AM,Saad Vsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
49-51issue
7eissn
0040-3660issn
2309-5342journal_volume
65pub_type
杂志文章abstract:AIM:To study dynamics of transmitral circulation (TMC) during a hemodialysis (HD) session in patients with chronic renal failure (CRF) regarding structural-functional alterations of the heart and baseline condition of the diastolic function of left ventricular (LV) myocardium. MATERIAL AND METHODS:Sixty one patients (...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Altogether 117 case reports were analyzed and 32 patients with associated gastric or duodenal ulcer and coronary heart disease (CHD) as well as 48 controls suffering from gastric or duodenal ulcer were examined. A relationship was established between the clinical picture and the course of associated ulcer disease and ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The authors provide the data of many years of study into the morphofunctional status of the gastroduodenal system in 396 patients with peptic ulcer exposed to staged rehabilitation treatment. High medical and economic efficacy of the method is demonstrated. Approaches to the improvement of the results of staged rehabi...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::In the review article are provided the approaches to the therapy for improvement of prognosis in patients with peripheral and multifocal atherosclerosis which are available now; some limitations and a real situation are designated for the antithrombotic therapy in this category of patients. According to the clinical t...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:10.26442/00403660.2019.12.000498
更新日期:2019-12-15 00:00:00
abstract::Biological methods are widely used in the treatment of intestinal inflammation (II). The TNFalpha inhibitor infliximab can quickly correct recurrence, provide long-term remission and reduce hormone need in many patients with hormone-resistant and hormone-dependent forms of Crohn's disease (CD) and ulcerative colitis (...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::After prosthetics of the aortal valve 30 patients underwent bicycle ergometry training at the sanatorial stage of rehabilitation. 10 patients who did not undergo bicycle ergometry training made up the control group. The efficacy of bicycle ergometry training was assessed according to the time-course of changes in pump...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:AIM:To characterize the spectrum, incidence rate and features of pulmonary pathology in HIV-infected inpatients with reference to a fall in the count of CD4-lymphocytes. MATERIAL AND METHODS:A total of 2370 patients with HIV infection admitted to Moscow infectious hospital N 2 were examined. The protocol of examinatio...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:AIM:To analyze the incidence of primary immunodeficiencies (PIDs), to reveal the specific features of the course of this condition at the present stage, and to estimate the quality of health care to patients with PIDs. SUBJECTS AND METHODS:An open-label prospective trial was performed in 94 patients with different for...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:AIM:To study causes and sequelae of intradialysis hypotension (IH) in patients with terminal renal failure (TRF). MATERIAL AND METHODS:Forty one patients with TRF on chronic hemodialysis (CH) were divided into two groups. The study group consisted of 24 patients with episodes of IH. Seventeen patients of the control g...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::A study was made of the impact of a single intake of nifedipine, intal, sodium thiosulfate and essentiale on respiratory function, the blood content of ionized calcium, total calcium, hydroperoxides, total and non-protein thiol groups, and prostaglandins in bronchial asthma patients. All the drugs exerted an antioxida...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The authors studied the economic efficacy of 5-year follow-up and treatment of AH patients at the population level. An opportunity of a considerable decrease in AH morbidity and mortality was shown. In the intervention group all expenditures on AH control after 5-year treatment payed back 3-fold. ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:AIM:to analyze well-known risk factors (RFs), such as age, immunophenotype, baseline leukocytosis, enhanced lactate dehydrogenase (LDH) activity, time to achieve complete remission, a risk group, and cytogenetic abnormalities) in patients with acute lymphoblastic leukemia (ALL) in the use of the ALL-2009 protocol. SUB...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh201688715-24
更新日期:2016-01-01 00:00:00
abstract::The examination covered 44 patients (16 males and 28 females) with chronic bronchitis (CB) associated with diseases of the nose and paranasal sinuses. Most of the patients (63.6%) had allergic rhinosinusopathy (ARSP). The kind of nasal and sinus affection varied with CB form (catarrhal or purulent). Aggravation of ENT...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The case report of botulinum toxin treatment of gastroparesis in a patient following allogenic bone marrow transplantation is described. The causes of gastroparesis and methods of prevention and treatment are discussed. It was noted that pyloric injection of botulinum toxin can improve symptoms and gastric emptying. ...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/terarkh201890160-64
更新日期:2018-02-14 00:00:00
abstract::Deciphering immunopathogenesis, expanding the scope of diagnostics and developing new methods for treating human autoimmune diseases are among the priority areas of XXI century medicine. Particularly widely autoimmune pathology is presented in immunoinflammatory rheumatic diseases (IIRD), such as rheumatoid arthritis,...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/00403660.2019.08.000406
更新日期:2019-08-15 00:00:00
abstract:AIM:To investigate clinical efficacy of angiotensin-converting enzyme inhibitor trandolapril and its effects on myocardial function. MATERIALS AND METHOD:20 patients with ischemic heart disease (IHD) aged 33-74 years with chronic cardiac failure NYHA class II-IV. 4 of them survived myocardial infarction. In addition t...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:AIM:To assess efficacy of cyclopheron (Polysan production) as opisthorchiasis pretreatment in patients with chronic viral hepatitis C (CHC). MATERIAL AND METHODS:Fifteen CHC patients received cyclopheron by 6 month scheme before dehelminthization. The effect was evaluated by dynamics of clinical symptoms, results of f...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:AIM:To identify emergencies in rural dwellers during electrocardiographic examination using a tele-electrogram (ECG) analysis (Easy ECG) system. MATERIALS AND METHODS:The easy ECG system connected 4 therapeutic-and-prophylactic institutions of a rural area and the town of Uryupinsk with the Research Institute of Cardi...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::Despite the success in increasing the effectiveness of treatment of arterial hypertension (AH), frequency of achieving target levels of blood pressure (BP) in hypertensive patients and the scope of their regular supervision in most countries of the world, including in the Russian Federation are insufficient. Modern te...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.26442/terarkh20189014-8
更新日期:2018-01-09 00:00:00
abstract:AIM:To evaluate the effect of ACE inhibitor enalapril, AR blocker candesartan and their combination on left ventricular hypertrophy (LVH) and content of biochemical markers of collagen balance in patients with hypertensive LV hypertrophy. MATERIAL AND METHODS. A total of 66 patients with arterial hypertension with LV h...
journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:AIM:To study characteristics of iron deficiency anemia (IDA) in native population of high altitude territories. MATERIAL AND METHODS:1300 women living in Tien-Shan areas were examined for serum and erythrocytic ferritins (SF and EF), general iron-binding capacity of the serum, transferrin saturation with iron, transfe...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:AIM:To assess efficacy of two- and three-component antihypertensive treatment (AHT) in patients with severe sleep apnea and arterial hypertension (AH) of the second and third degree in combination with CPAP therapy (continuous positive air pressure) and without it. MATERIAL AND METHODS:A total of 58 patients aged 55.5...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::A clinical-morphological study of bronchobiopsies from 78 patients with endoscopic picture of atrophic endobronchitis was carried out. Two forms of morphogenesis of chronic atrophic process in the bronchial mucosa are distinguished: primary dystrophic and primary inflammatory. Primary dystrophic bronchopathy is a clin...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:AIM:To study possible correction of bone disorders (osteopenia, Ca/P-imbalance, bone pain, limited volume of indolent movements) which are still a serious complication associated with renal diseases and pathogenic therapy (steroids). MATERIALS AND METHODS:The bone disorders were treated in 10 uremic hemodialyzed patie...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:AIM:To evaluate prevalence of bronchial asthma (BA) and allergic rhinitis (AR) among adult population of St-Petersburg. MATERIAL AND METHODS:Responders to ECRHS and B. Sibbald & E. Rink questionnaires who gave at least one positive answer were examined clinically, functionally and allergologically. A total of 3634 res...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:AIM:To elucidate whether secretory phospholipase A2 (sPLA2) level in the blood and catalytic activity are significant predictors of restenosis after coronary angioplasty (CAP). MATERIAL AND METHODS:Samples of venous blood were obtained from 24 patients before CAP and 1, 3, 6 days and 6 months after it. sPLA2 was measu...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:AIM:To assess the prevalence of bacterial overgrowth syndrome (BOS) and its risk factors in patients with inflammatory bowel diseases (IBD). SUBJECTS AND METHODS:The patients from the Novosibirsk IBD registry, who had undergone a hydrogen breath test (HBT) using a Gastro+ device, were examined. RESULTS:In 93 IBD pati...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:10.17116/terarkh201789215-19
更新日期:2017-01-01 00:00:00
abstract::The data obtained in a prospective study made it possible, using Markov's analysis, to assess different forms of coronary heart disease (CHD) of long duration and to elaborate an unsophisticated scale for estimating individual risk of death from that disease. The Markov's analysis demonstrated a high enough probabilit...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Lipid peroxidation, antioxidant defense and microrheological properties of blood were determined, correlated and compared with clinico-hemodynamic indices in patients with ischemic heart disease (IHD). It is shown that products of lipid peroxidation modify structure and function of red cells and platelets in IHD. A re...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The authors review literature data on porphyrias with combining enzymopathies in heme biosynthesis system, report a case of porphyria cutanea tarda and porphyria variegata registered simultaneously in a male patient clinically and confirmed biochemically. The patient's mother had elevated levels of fecal protoporphyri...
journal_title:Terapevticheskii arkhiv
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00