Abstract:
AIM:To study possible correction of bone disorders (osteopenia, Ca/P-imbalance, bone pain, limited volume of indolent movements) which are still a serious complication associated with renal diseases and pathogenic therapy (steroids). MATERIALS AND METHODS:The bone disorders were treated in 10 uremic hemodialyzed patients (8 men, 2 women; group 1) with vitamin D3 (calcitriol made in Russia) + rhEPO (recormon; Boehringer Mannheim), in 15 patients (15 women, 0 men) with lupus-nephritis (group 2) with vitamin D3 (n = 5, group 2a) or miscalcic (Sandoz) (n = 10, group 2b), in 2 patients (2 men, 0 women) with glomerulonephritis (group 3) with vitamin D3 + miacalcic. Additionally all the patients received Ca salts. In groups 2 and 3 renal function was normal. The duration of the treatment was 3-6 months. RESULTS:In all the groups we obtained an analgetic effect (attenuation of bone pain and more indolent movements), improvement of life quality, diminished need in analgetics, elevation of serum Ca level (p > 0.05). CONCLUSION:Treatment of renal patients with bone affection with vitamin D3 and miacalcic has an analgetic effect, improves life quality.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Kukhtevich AV,Krasnova TN,Nikolaev AIu,Rodionova SS,Milovanova LIusubject
Has Abstractpub_date
1999-01-01 00:00:00pages
59-62issue
8eissn
0040-3660issn
2309-5342journal_volume
71pub_type
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journal_title:Terapevticheskii arkhiv
pub_type: 临床试验,杂志文章
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journal_title:Terapevticheskii arkhiv
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journal_title:Terapevticheskii arkhiv
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