The electrophysiological expression of Ca2+ channels and of apamin sensitive Ca2+ activated K+ channels is abolished in skeletal muscle cells from mice with muscular dysgenesis.

abstract：:At an early stage of apoptosis, Jurkat cells transiently become susceptible to binding and phagocytosis by macrophages through the polylactosamine-type carbohydrate chains of CD43 [J. Biol. Chem. 279 (2004) 5967]. Susceptibility of apoptotic Jurkat cells to macrophage recognition was studied over an extended time rang...

journal_title：Biochemical and biophysical research communications

authors： Yamanaka M,Eda S,Beppu M

更新日期：2005-03-04 00:00:00

abstract：:Insulin activates the glucose transport in isolated fat cells through a translocation of the insulin sensitive glucose carrier subtype (GLUT4) and by activation of glucose carriers in the plasma membrane. Protein kinase C stimulating phorbol esters are able to mimick partially the insulin effect on glucose transport. ...

journal_title：Biochemical and biophysical research communications

authors： Vogt B,Mushack J,Seffer E,Häring HU

更新日期：1990-05-16 00:00:00

abstract：:The smallest protein of hepatitis B virus, HBX, has been implicated in the development of liver diseases by interfering with normal cellular processes. Its role in cell proliferation has been unclear as both pro-apoptotic and anti-apoptotic activities have been reported. We showed molecular evidence that HBX induced a...

journal_title：Biochemical and biophysical research communications

authors： Lu YW,Chen WN

更新日期：2005-12-23 00:00:00

abstract：:Rice, a monocot model crop, contains at least 48 putative E2 ubiquitin (Ub)-conjugating enzymes. Based on homology comparisons with 40 Arabidopsis E2 proteins and 35 human E2s, 48 rice E2s were classified into 15 different groups. Yeast two-hybrid analyses using the U-box-domain regions of armadillo (ARM)-U-box E3 Ub-...

journal_title：Biochemical and biophysical research communications

authors： Bae H,Kim WT

更新日期：2014-02-21 00:00:00

abstract：:Molecular chaperones prevent the aggregation of partially folded or misfolded forms of protein. alpha-crystallin performs such a function in the ocular lens. To gain insight into the mechanism of the anti-aggregation activity of alpha-crystallin, we performed dynamic light scattering (DLS) measurements investigating i...

journal_title：Biochemical and biophysical research communications

authors： Bettelheim FA,Ansari R,Cheng QF,Zigler JS Jr

更新日期：1999-08-02 00:00:00

abstract：:Chromatography of chicken liver AMP deaminase on phosphocellulose and DEAE-Sephacel revealed the existence of two separate peaks of enzyme activity. Significant differences have been observed between form I and II of the enzyme in respect to substrate specificity and their kinetic and regulatory properties. ...

journal_title：Biochemical and biophysical research communications

authors： Spychała J,Makarewicz W

更新日期：1983-08-12 00:00:00

abstract：:Platelets play essential roles in hemostasis and thrombosis by aggregating with each other. However, the molecular mechanism governing platelet aggregation is not yet fully understood. Here, we established an assay system using platelets permeabilized with streptolysin-O to analyze mechanism of the thrombin-induced ag...

journal_title：Biochemical and biophysical research communications

authors： Nishioka H,Horiuchi H,Tabuchi A,Yoshioka A,Shirakawa R,Kita T

更新日期：2001-02-02 00:00:00

abstract：:We tested the hypothesis that adrenomedullin (ADM), a recently isolated hypotensive peptide, is an autocrine transmitter in renal arterial smooth muscle cells (RASMCs). Fura-2 fluorometry revealed that ADM decreases both the cytosolic Ca2+ concentration ([Ca2+]i) and tension induced by 0.3 microM phenylephrine (PE) in...

journal_title：Biochemical and biophysical research communications

authors： Seguchi H,Nishimura J,Kobayashi S,Kumazawa J,Kanaide H

更新日期：1995-10-13 00:00:00

abstract：:HMG 14 and protamine can be used to enhance intermolecular ligation of low concentrations of linear DNA. Adding HMG 14 (50 moles per mole DNA) caused 50% of blunt-ended DNA to form predominantly dimers, and all cohesive-ended DNA to form multimers (greater than 6-mer) in response to T4 ligase. Protamine was maximally ...

journal_title：Biochemical and biophysical research communications

authors： Sheflin LG,Fucile NW,Spaulding SW

更新日期：1991-01-31 00:00:00

abstract：:Structures arising from actin-based cell membrane movements, including ruffles, lamellipodia, and filopodia, play important roles in a broad spectrum of cellular functions, such as cell motility, axon guidance in neurons, wound healing, and micropinocytosis. Previous studies investigating these cell membrane dynamics ...

journal_title：Biochemical and biophysical research communications

authors： Ueda Y,Sato M

更新日期：2018-11-25 00:00:00

abstract：:Previously, we have investigated the potential for a pro-oxidant interaction of iron and ascorbate in vivo in iron and ascorbate cosupplementation or ascorbate supplementation studies. In this study, for the first time, the effects of iron supplementation on oxidative damage to DNA in healthy individuals with plasma a...

journal_title：Biochemical and biophysical research communications

authors： Proteggente AR,England TG,Rice-Evans CA,Halliwell B

更新日期：2001-10-19 00:00:00

abstract：:Human thymidine phosphorylase (dThdPase) is thought to be identical to an angiogenesis factor, platelet-derived endothelial cell growth factor (PD-ECGF). However, the whole amino acid sequence of dThdPase is still unknown. N-terminal amino acid sequencing of dThdPase isolated from human placenta gave the sequence Ac-A...

journal_title：Biochemical and biophysical research communications

authors： Miyadera K,Dohmae N,Takio K,Sumizawa T,Haraguchi M,Furukawa T,Yamada Y,Akiyama S

更新日期：1995-07-26 00:00:00

abstract：:Sleep deprivation (SD) has detrimental effects on the physiological function of the brain. However, the underlying mechanism remains elusive. In the present study, we investigated the expression of candidate plasticity-related gene 15 (cpg15), a neurotrophic gene, and its potential role in SD using a REM-SD mouse mode...

journal_title：Biochemical and biophysical research communications

authors： Li CJ,Li JJ,Jiang Y,Mu YW,Lu DX,Xiao ZY,Jiang HY,Zhao JJ,Chen XH

更新日期：2020-02-12 00:00:00

abstract：:Daudi lymphoma cells, of a line sensitive to growth inhibition by alpha interferon, showed dose-dependent plasma membrane depolarization within 10 min after exposure to natural or recombinant alpha interferons (10 to 1000 IU/ml). This biophysical change was detected flow cytometrically by measuring the intensity of fl...

journal_title：Biochemical and biophysical research communications

authors： Grimley PM,Aszalos A

更新日期：1987-07-15 00:00:00

abstract：:The root-knot nematode (RKN) Meloidogyne incognita reproduces on the roots of tobacco (Nicotiana tabacum), damaging crops, reducing crop yield, and causing economic losses annually. The development of resistant genotypes is an alternative strategy to effectively control these losses. However, the molecular mechanism r...

journal_title：Biochemical and biophysical research communications

authors： Xing X,Li X,Zhang M,Wang Y,Liu B,Xi Q,Zhao K,Wu Y,Yang T

更新日期：2017-01-22 00:00:00

abstract：:Screening for inhibitors of DNA-dependent protein kinase (DNA-PK) revealed 3-cyano-5-(4-pyridyl)-6-hydrazonomethyl-2-pyridone, designated OK-1035, to be a potent and selective inhibitor. When a synthetic peptide was used as a substrate, OK-1035 caused 50% inhibition of DNA-PK activity at 8 microM, a concentration more...

journal_title：Biochemical and biophysical research communications

authors： Take Y,Kumano M,Hamano Y,Fukatsu H,Teraoka H,Nishimura S,Okuyama A

更新日期：1995-10-04 00:00:00

abstract：:Inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, are persistent disorders that lead to development of colitis-associated cancer (CAC). Facilitated resolution of colitis has been addressed as a novel therapeutic strategy to control development of CAC. Resolvin D1 (RvD1) is an endogenous li...

journal_title：Biochemical and biophysical research communications

authors： Zhong X,Lee HN,Surh YJ

更新日期：2018-02-05 00:00:00

abstract：:Cancer cell molecular mimicry of stem cells (SC) follows with enhanced proliferative and renewal capacities. In support, numerous mediators of SC self-renewal have been evinced to exhibit oncogenic potential. More and more researches showed that the embryonic stem cell self-renewal genes express in various cancer cell...

journal_title：Biochemical and biophysical research communications

authors： Deng L,Xiang X,Yang F,Xiao D,Liu K,Chen Z,Zhang R,Feng G

更新日期：2017-08-19 00:00:00

abstract：:Receptors for atrial natriuretic peptide (ANP) are heterogeneous: an approximately 140-kDa receptor exhibits ANP-stimulated guanylate cyclase activity whereas an approximately 65-kDa receptor is thought to act only as a clearance-storage protein. We have used photoaffinity labeling techniques to show that the human ce...

journal_title：Biochemical and biophysical research communications

authors： Watt VM,Yip CC

更新日期：1989-10-31 00:00:00

abstract：:alpha-Crystallin, a major eye lens protein, has been shown to function like a molecular chaperone by suppressing the aggregation of other proteins induced by various stress conditions. Ultraviolet (UV) radiation is known to cause structural and functional alterations in the lens macromolecules. Earlier we observed tha...

journal_title：Biochemical and biophysical research communications

authors： Reddy GB,Reddy PY,Suryanarayana P

更新日期：2001-04-06 00:00:00

abstract：:Pyrrolidine dithiocarbamate (PDTC) is a synthetic antioxidant molecule, which has been recently proposed as an antitumoral agent on the basis of its capability of inducing apoptosis. We investigated the effect of PDTC on the proliferation and survival of the promyelocitic cell line HL-60. Concentration as low as 10 mi...

journal_title：Biochemical and biophysical research communications

authors： Della Ragione F,Cucciolla V,Borriello A,Della Pietra V,Manna C,Galletti P,Zappia V

更新日期：2000-02-24 00:00:00

abstract：:Stimulation of neutrophils with LTB(4) or PAF results in the production of a rapidly oscillating actin polymerization/depolymerization response. Treatment of neutrophils with inhibitors of PKC prior to stimulation with ligand resulted in a masking of the F-actin oscillations. Because myosin has been shown to be a subs...

journal_title：Biochemical and biophysical research communications

authors： Rengan R,Omann GM

更新日期：1999-08-27 00:00:00

abstract：:A procedure was developed for real-time measurement of the interaction between an archaeal TATA-binding protein (TBP) with stress-gene promoters from the archaeon Methanosarcina mazeii using surface plasmon resonance (SPR), the BIACORE 3000 equipment, and the SA (streptavidin) Sensor Chip. Measurements were based on t...

journal_title：Biochemical and biophysical research communications

authors： Conway de Macario E,Rudofsky UH,Macario AJ

更新日期：2002-11-15 00:00:00

abstract：:Sortase enzymes belong to a family of transpeptidases found in Gram-positive bacteria. Sortase is responsible for the reaction that anchors surface protein virulence factors to the peptidoglycan cell wall of the bacteria. The compound (Z)-3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl) acrylonitrile (DMMA) has previously ...

journal_title：Biochemical and biophysical research communications

authors： Oh KB,Nam KW,Ahn H,Shin J,Kim S,Mar W

更新日期：2010-05-28 00:00:00

abstract：:Sterols are essential membrane components of eukaryotic cells and are important for membrane organization and function. Cholesterol is the most representative sterol present in higher eukaryotes. It is often found distributed non-randomly in domains or pools in biological and model membranes. Cholesterol-rich function...

journal_title：Biochemical and biophysical research communications

authors： Arora A,Raghuraman H,Chattopadhyay A

更新日期：2004-06-11 00:00:00

abstract：:Lipoproteins are important biological components. However, they have few convenient fluorescent labelling probes currently reported, and their physiological reliability can be questioned. We compared the association of two fluorescent cholesterol derivatives, 22-nitrobenzoxadiazole-cholesterol (NBD-Chol) and 21-methyl...

journal_title：Biochemical and biophysical research communications

authors： Gaibelet G,Tercé F,Bertrand-Michel J,Allart S,Azalbert V,Lecompte MF,Collet X,Orlowski S

更新日期：2013-11-01 00:00:00

abstract：:We examined the effects of angiotensin II (Ang II) on the proliferation of osteoblast-rich populations of cells obtained from calvariae of newborn rat. Addition of Ang II to the culture medium caused dose-dependent increases in the rate of DNA synthesis. Such increases were completely inhibited by the addition of DuP7...

journal_title：Biochemical and biophysical research communications

authors： Hiruma Y,Inoue A,Hirose S,Hagiwara H

更新日期：1997-01-03 00:00:00

abstract：:Poly(ADP-ribose) polymerase (ADPRP) is a nuclear enzyme that transfers ADP-ribose from NAD+ to diverse nuclear proteins. Previously, the function of ADPRP was considered to relate exclusively to its catalytic activity. However, recent experiments have shown that ADPRP is actually an abundant DNA-binding protein, and t...

journal_title：Biochemical and biophysical research communications

authors： Nobori T,Yamanaka H,Carson DA

更新日期：1989-09-15 00:00:00

abstract：:By its antioxidant effect, molecular hydrogen gas (H2) was reported to protect organs from tissue damage induced by ischemia reperfusion. To evaluate its anti-inflammatory effects, we established a mouse model of human inflammatory bowel disease (IBD) by supplying mice with water containing (1) dextran sodium sulfate ...

journal_title：Biochemical and biophysical research communications

authors： Kajiya M,Silva MJ,Sato K,Ouhara K,Kawai T

更新日期：2009-08-14 00:00:00

abstract：:We report on a system to improve expression of mature c-type cytochromes in Escherichia coli. It is based on the use of plasmid pEC86 that expresses the E. coli cytochrome c maturation genes ccmABCDEFGH constitutively, whereby the production of both endogenous and foreign c-type cytochromes was increased substantially...

journal_title：Biochemical and biophysical research communications

authors： Arslan E,Schulz H,Zufferey R,Künzler P,Thöny-Meyer L

更新日期：1998-10-29 00:00:00