Abstract：
:1. Antidromic stimulation of the visual radiation of cats has been used to investigate the possibility that some of the activity in principal geniculate cells following an optic tract stimulus is antidromic. Single spikes were selected from two classes of poststimulus activity to condition the antidromic test spike--the undoubted orthodromic postsynaptic spike and the later spikes, occurring up to 100 ms after the optic tract stimulus. 2. In 15 of 39 cells the minimum antidromic activation times and the minimum spike-spike intervals were found to be shorter and latencies for antidromic stimulation were longer when the conditioning spikes belonged the class of late poststimulus activity. The differences are in accord with the assumption that some of the conditioning spikes were antidromic. 3. Test spikes were frequently found to have long and variable latency when the conditioning spike occurred more than 45 ms after the optic tract stimulus. Possible reasons are briefly discussed. 4. It is suggested that antidromic activity may occur in conditions of the cortex that are more physiological than those associated with a penicillin-induced seizure focus. Some possible mechanisms and functional significance are briefly discussed.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Rosen AD,Vastola EFdoi
10.1152/jn.1977.40.1.9subject
Has Abstractpub_date
1977-01-01 00:00:00pages
9-15issue
1eissn
0022-3077issn
1522-1598journal_volume
40pub_type
杂志文章abstract：:A description of healthy and pathological brain dynamics requires an understanding of spatiotemporal patterns of neural activity and characteristics of its propagation between interconnected circuits. However, the structure and modulation of the neural activation maps underlying these patterns and their propagation re...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00708.2011
更新日期：2012-07-01 00:00:00
abstract：:We examined how subjects plan speeded reaching movements when the precise target of the movement is not known at movement onset. Before each reach, subjects were given only a probability distribution on possible target positions. Only after completing part of the movement did the actual target appear. In separate expe...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00858.2007
更新日期：2007-11-01 00:00:00
abstract：:Cold-sensitive and nociceptive neural pathways interact to shape the quality and intensity of thermal and pain perception. Yet the central processing of cold thermosensation in the human brain has not been extensively studied. Here, we used magnetoencephalography and EEG in healthy volunteers to investigate the time c...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00843.2016
更新日期：2017-05-01 00:00:00
abstract：:The auditory frequency-following response (FFR) reflects synchronized and phase-locked activity along the auditory pathway in response to sound. Although FFRs were historically thought to reflect subcortical activity, recent evidence suggests an auditory cortex contribution as well. Here we present electrophysiologica...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00112.2019
更新日期：2019-08-01 00:00:00
abstract：:1. Models of the saccadic system propose that there is an integration of the pulse signal, and there is good evidence that the integrator is reset gradually (Nichols and Sparks 1994, 1995). Other studies of the superior collicular contribution to the saccadic system have proposed a sensory, not motor, nature for its s...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1995.73.4.1724
更新日期：1995-04-01 00:00:00
abstract：:Slow covariations in neuronal resting potentials can lead to artefactually fast cross-correlations in their spike trains. J. Neurophysiol. 80: 3345-3351, 1998. A model of two lateral geniculate nucleus (LGN) cells, which interact only through slow (tens of seconds) covariations in their resting membrane potentials, is...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1998.80.6.3345
更新日期：1998-12-01 00:00:00
abstract：:In the oscillatory circuits known as central pattern generators (CPGs), most synaptic connections are inhibitory. We have assessed the effects of inhibitory synaptic input on the dynamic behavior of a component neuron of the pyloric CPG in the lobster stomatogastric ganglion. Experimental perturbations were applied to...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1999.82.1.115
更新日期：1999-07-01 00:00:00
abstract：:We have recently demonstrated that application of the mustard oil (MO), a small-fiber excitant and inflammatory irritant, to the rat maxillary molar tooth pulp induces significant increases in jaw muscle electromyographic (EMG) activity and neuroplastic changes in trigeminal (V) subnucleus caudalis. Since subnucleus o...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.2001.85.5.1836
更新日期：2001-05-01 00:00:00
abstract：:The spatial arrangement of preferred directions (PDs) in the primary motor cortex has revealed evidence for columnar organization and short-range order. We investigated the large-scale properties of this arrangement. We recorded neural activity at sites on a grid covering a large region of the arm area of the motor co...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00488.2006
更新日期：2006-12-01 00:00:00
abstract：:The continuous perception of motion-through-depth is critical for both navigation and interacting with objects in a dynamic three-dimensional (3D) world. Here we used 3D tracking to simultaneously assess the perception of motion in all directions, facilitating comparisons of responses to motion-through-depth to fronto...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00831.2016
更新日期：2017-09-01 00:00:00
abstract：:Macaque SEF neurons encode object-centered directions of eye movements regardless of the visual attributes of instructional cues. Neurons in the supplementary eye field (SEF) of the macaque monkey exhibit object-centered direction selectivity in the context of a task in which a spot flashed on the right or left end of...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1999.81.5.2340
更新日期：1999-05-01 00:00:00
abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1999.82.1.10
更新日期：1999-07-01 00:00:00
abstract：:1. K+ conductances were characterized in isolated, identified superior colliculus-projecting (SCP) rat visual cortical neurons. SCP neurons were identified in vitro under epifluorescence illumination after in vivo retrograde labeling with rhodamine-labeled microspheres or "beads." For experiments, SCP neurons were iso...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1995.73.6.2163
更新日期：1995-06-01 00:00:00
abstract：:We investigated the postnatal development of axon sensitivity to the withdrawal of oxygen, glucose, or the combined withdrawal of oxygen + glucose in the isolated rat optic nerve (a CNS white matter tract). Removal of either oxygen or glucose for 60 min resulted in irreversible injury in optic nerves from adult rats, ...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1998.79.1.95
更新日期：1998-01-01 00:00:00
abstract：:1. Microelectrode recordings from 15 slowly adapting (SA) cutaneous mechanoreceptor afferents originating in hairy skin were obtained from the radial nerve in humans. 2. Controlled skin stretch was applied to the back of the hand that encompassed the physiological range of skin stretch during movements at the metacarp...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1992.67.5.1105
更新日期：1992-05-01 00:00:00
abstract：:The medial division of the ventral nucleus of the lateral lemniscus (VNLLm) contains a specialized population of neurons that is sensitive to interaural temporal disparities (ITDs), a potent cue for sound localization along the azimuth. Unlike many ITD-sensitive neurons elsewhere in the auditory system, neurons in the...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.2002.88.2.666
更新日期：2002-08-01 00:00:00
abstract：:The mechanical state encoded by slowly adapting type 1 mechanoreceptors (SAI) during indentation was examined using an isolated preparation in a rat model. Skin and its intact innervation were harvested from the medial thigh of the rat hindlimb and placed in a dish, with the corium side down, containing synthetic inte...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00414.2001
更新日期：2002-04-01 00:00:00
abstract：:The human motor system regulates arm mechanics to produce stable postures during interactions with different physical environments. This occurs partly via involuntary mechanisms, including stretch reflexes. Previous single-joint studies demonstrated enhanced reflex sensitivity during interactions with compliant enviro...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.01094.2007
更新日期：2008-05-01 00:00:00
abstract：:We studied the effects of horizontal smooth pursuit on the ocular responses to brief vertical perturbations of textured backgrounds in humans. When the subject was fixating on a stationary target, a brief vertical perturbation of the background elicited a small tracking response. When the subject was pursuing a target...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00430.2009
更新日期：2009-09-01 00:00:00
abstract：:The respective roles of ventral and dorsal cortical processing streams are still under discussion in both vision and audition. We characterized neural responses in the caudal auditory belt cortex, an early dorsal stream region of the macaque. We found fast neural responses with elevated temporal precision as well as n...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00436.2013
更新日期：2014-04-01 00:00:00
abstract：:Subjects were asked to track, with their eyes or their hand, the movement of a target that maintained a constant speed and made a single, abrupt change in direction. The tracking speed and direction of motion after the step change in target direction were compared for the eyes and the hand. After removal of the saccad...
journal_title：Journal of neurophysiology
pub_type： 临床试验,杂志文章
doi：10.1152/jn.2000.84.3.1149
更新日期：2000-09-01 00:00:00
abstract：:1. Intracellular recordings from CA1 pyramidal neurons in the rat hippocampal slice have been used to study synaptic transmission after maximal orthodromic stimulation of the Schaffer collateral-commissural fibers. Paired-pulse stimulation was used to investigate how the first (conditioning) stimulation influenced the...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1991.66.5.1704
更新日期：1991-11-01 00:00:00
abstract：:Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rat...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00061.2007
更新日期：2007-05-01 00:00:00
abstract：:1. We have examined the effects of iontophoresing specific antagonists to excitatory amino acid receptors on the visual responses of cells in lamina A or A1 of the cat's lateral geniculate nucleus (LGN). 2. Cells were classified as On- or Off-center, X or Y, and lagged or nonlagged. The effects of antagonists were stu...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1991.66.2.414
更新日期：1991-08-01 00:00:00
abstract：:1. Neuronal mechanisms for decoding sound azimuth and angular movement were studied by recordings of several single units in parallel in the core areas of the auditory cortex of the macaque monkey. The activity of 180 units was recorded during the presentation of moving and static sound stimuli. Both the activity of s...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1992.67.1.203
更新日期：1992-01-01 00:00:00
abstract：:Recognition of sound patterns must be largely independent of level and of masking or jamming background sounds. Auditory patterns of relevance in numerous environmental sounds, species-specific vocalizations and speech are frequency modulations (FM). Level-dependent activation of the human auditory cortex (AC) in resp...
journal_title：Journal of neurophysiology
pub_type： 临床试验,杂志文章
doi：10.1152/jn.00187.2001
更新日期：2002-01-01 00:00:00
abstract：:1. Neurons (n = 142) were recorded with extracellular micropipettes in the parabrachial (PB) area, in the anesthetized rat, some of them being antidromically driven from the centralis nucleus of the amygdala (Ce). The spontaneous activity of these neurons was low, (10th percentile < median frequency < 90th percentile;...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1994.71.5.1646
更新日期：1994-05-01 00:00:00
abstract：:Single-unit recordings were made from layer II/III anterior piriform cortex (aPCX) neurons in adult Wistar rats to examine odor response patterns to unilaterally and bilaterally delivered stimuli. Isoamyl acetate odor stimulation was presented either unilaterally through tubes inserted into the external nares, or bila...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1997.78.1.160
更新日期：1997-07-01 00:00:00
abstract：:Electrophysiological properties of the ventral giant axon in the abdominal nerve cord of the cockroach were studied by recording intracellular potentials following partial or complete block of the K+ conductance. When the K+ conductance was completely blocked by tetraethylammonium (TEA) and 3,4-diaminopyridine, the in...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.1985.54.5.1087
更新日期：1985-11-01 00:00:00
abstract：:Generalization is a fundamental aspect of behavior, allowing for the transfer of knowledge from one context to another. The details of this transfer are thought to reveal how the brain represents what it learns. Generalization has been a central focus in studies of sensorimotor adaptation, and its pattern has been wel...
journal_title：Journal of neurophysiology
pub_type： 杂志文章
doi：10.1152/jn.00974.2016
更新日期：2017-07-01 00:00:00
