Effect of a low salt diet on blood pressure and vasoactive hormones in the hereditary hypertriglyceridemic rat.

Abstract:

:In hereditary HTG rats, basal systolic blood pressure using tail-cuff sphygmomanometry was significantly higher (122.1 +/- 2.1 mm Hg; n = 16) than that in NTG animals (107.1 +/- 1.52; n = 16). A low salt diet did not influence blood pressure in NTG rats during the consecutive 4 weekly periods. However, in the second week blood pressure in HTG rats rose significantly in both the control rats on a normal salt diet and those on a low salt diet (132.5 +/- 1.89, n = 8, and 132.6 +/- 1.93, n = 8). No further changes were registered in the third and fourth week in control HTG rats. On the other hand, blood pressure fell significantly in HTG rats on a low salt diet in the third week in comparison with the second week (119.5 +/- 3.2, n = 8), and it increased again in the fourth week (123.0 +/- 2.35, n = 8). Hormones in plasma were determined at the end of the experiment. Plasma levels of norepinephrine were not influenced by differences in salt intake and were significantly higher by about 45% in HTG than in NTG animals. The lowest concentration of corticosterone in plasma was found in control HTG rats (1.2 +/- 0.2 vs 4.6 +/- 0.8 micrograms/100 ml in control NTG rats). Nevertheless, corticosterone concentration increased in HTG rats on a low salt diet at comparable values found in NTG rats on a low salt diet (3.1 +/- 0.8 vs 4.3 +/- 1.5). Plasma renin activity and plasma aldosterone concentrations were not different in the NTG and HTG groups and were uninfluenced by the diets (Table 1). We conclude that the elevated blood pressure in HTG rats and its variations during the experiment may reflect more pronounced sympathetic activity in HTG rats rather than blood pressure dependency on different salt intake.

journal_name

Ann N Y Acad Sci

authors

Lichardus B,Seböková E,Jezová D,Mitková A,Zemánková A,Földes O,Vrána A,Klimes I

doi

10.1111/j.1749-6632.1993.tb35719.x

subject

Has Abstract

pub_date

1993-06-14 00:00:00

pages

289-94

eissn

0077-8923

issn

1749-6632

journal_volume

683

pub_type

杂志文章
  • Positron emission tomography for measurement of copper fluxes in live organisms.

    abstract::Copper is an essential nutrient for the physiology of live organisms, but excessive copper can be harmful. Copper radioisotopes are used for measurement of copper fluxes in live organisms using a radioactivity assay of body fluids or whole-body positron emission tomography (PET). Hybrid positron emission tomography-co...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/nyas.12383

    authors: Peng F

    更新日期:2014-05-01 00:00:00

  • Anaplasmosis: focusing on host-vector-pathogen interactions for vaccine development.

    abstract::Anaplasma marginale and A. phagocytophylum are intracellular rickettsiae that cause bovine anaplasmosis and human granulocytic anaplasmosis, respectively. The ultimate vaccine for the control of anaplasmosis would be one that reduces infection and transmission of the pathogen by ticks. Effective vaccines for control o...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1374.081

    authors: de la Fuente J,Ayoubi P,Blouin EF,Almazán C,Naranjo V,Kocan KM

    更新日期:2006-10-01 00:00:00

  • Functional anatomical and behavioral consequences of dopamine receptor stimulation.

    abstract::Taken together with electrophysiological data, these results suggest that in states of DA deficiency, systemically administered L-dopa or DA agonist drugs inhibit cell firing in the major output nuclei of the basal ganglia (GPI and SNPR). We propose that DA produces this net effect by a direct influence on the striato...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1997.tb48626.x

    authors: Wooten GF

    更新日期:1997-12-19 00:00:00

  • Lack of N1L gene expression results in a significant decrease of vaccinia virus replication in mouse brain.

    abstract::Vaccinia virus encodes secretory proteins termed virokines. One of the major virokines encoded by the N1L open reading frame is the 13.8 kDa protein. A recombinant virus, termed vGK5, lacking this protein when injected intracranially into mice, has one of the highest levels of in vivo attenuation achieved by deletion ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1329.037

    authors: Billings B,Smith SA,Zhang Z,Lahiri DK,Kotwal GJ

    更新日期:2004-12-01 00:00:00

  • Some clues as to the regulation, expression, function, and distribution of fructosamine-3-kinase and fructosamine-3-kinase-related protein.

    abstract::Fructosamine-3-kinase (FN3K) and the more recently discovered fructosamine-3-kinase-related protein (FN3KRP) appear to protect proteins from nonenzymatic glycation. To gain a better understanding of these enzymes we performed a series of investigations including (1) in silico comparisons of their promoters; (2) real-t...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1333.095

    authors: Conner JR,Beisswenger PJ,Szwergold BS

    更新日期:2005-06-01 00:00:00

  • Expression and distribution of gonad-stimulating substance in various organs of the starfish Asterina pectinifera.

    abstract::Gonad-stimulating substance (GSS) is the first invertebrate gonadotropic neuropeptide hormone identified in a marine invertebrate, the starfish. Here, we show expression and distribution of GSS in various organs of the starfish Asterina pectinifera. Levels of GSS were high in the radial nerves and nerve ring. GSS was ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2008.03626.x

    authors: Mita M,Ito C,Kubota E,Nagahama Y,Shibata Y

    更新日期:2009-04-01 00:00:00

  • Analysis of V kappa I and V lambda II light chain genes in the expressed B-cell repertoire.

    abstract::Our previous studies of anti-DNA antibodies in SLE have demonstrated a preferential use of V kappa I and V lambda II gene families to encode light chains of antibodies that express the anti-DNA-associated 3I and 8.12 idiotypes, respectively. In this study, we employed PCR to obtain V kappa I and V lambda II germline g...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:

    authors: Manheimer-Lory A,Irigoyen M,Gaynor B,Monhian R,Splaver A,Diamond B

    更新日期:1995-09-29 00:00:00

  • Public health problem of zoonoses with emphasis on Q fever.

    abstract::Zoonoses are animal and human diseases. Q fever is primarily a zoonosis-an animal disease that can be transmitted to humans under certain conditions. Recent epidemiological studies suggest that Q fever should be considered as a public health problem in many countries where it is present, but unrecognizable due to inad...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1374.094

    authors: Beslagić E,Hamzić S,Beslagić O,Zvizdić S

    更新日期:2006-10-01 00:00:00

  • Karyotype-phenotype correlation in females with X chromosome abnormalities.

    abstract::In mammals, females have a pair of X chromosomes, whereas males have one X chromosome and one Y chromosome, which is much smaller and contains fewer genes than a X chromosome. One of the pair of X chromosomes is inactivated in females. The inactivated X chromosome is late-replicating, heterochromatic, and genetically ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1997.tb52164.x

    authors: Kosmaidou-Aravidou Z

    更新日期:1997-06-17 00:00:00

  • Some effects of exposure of the Japanese quail embryo to 2.45-GHz microwave radiation.

    abstract::Exposure of quail eggs 4 hr per day during the first 5 incubation days at 2450 MHz and in an exposure field of 30 mW/cm-2 and at an absorbed power of 14 mW/g does not cause any great change in body weight, observed gross malformations, rbc, wbc, hematocrit, hemoglobin, or differential wbc percentages. If small differe...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1975.tb36012.x

    authors: McRee DI,Hamrick PE,Zinkl J,Thaxton P,Parkhurst CR

    更新日期:1975-02-28 00:00:00

  • Synaptic plasticity in the mesolimbic system: therapeutic implications for substance abuse.

    abstract::In an ever-changing environment, animals must learn new behavioral strategies for the successful procurement of food, sex, and other needs. Synaptic plasticity within the mesolimbic system, a key reward circuit, affords an animal the ability to adapt and perform essential goal-directed behaviors. Ironically, drugs of ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2009.05154.x

    authors: Chen BT,Hopf FW,Bonci A

    更新日期:2010-02-01 00:00:00

  • Morphological evidence that xenon neuroprotects against N-methyl-DL-aspartic acid-induced damage in the rat arcuate nucleus: a time-dependent study.

    abstract::The hyperactivation of glutamate receptors, especially those of the N-methyl-d-aspartate subtype (NMDA), can induce excess calcium entry into cells, leading to neuronal death. Since the anesthetic gas xenon behaves as an NMDA antagonist, the present article investigated, by distinct morphological approaches and after ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1369.063

    authors: Natale G,Cattano D,Abramo A,Forfori F,Fulceri F,Fornai F,Paparelli A,Giunta F

    更新日期:2006-08-01 00:00:00

  • Detection of poliovirus antibodies and poliovirus genome in patients with the post-polio syndrome.

    abstract::To investigate the role of poliovirus (PV) infection in the development of the post-polio syndrome (PPS), we studied the serum, spinal fluid, peripheral blood lymphocytes, and muscle from 47 patients with PPS. We found high titers of IgM PV antibodies (up to 1:250) in the serum of 6 patients, compared to very low tite...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1995.tb27547.x

    authors: Leon-Monzon ME,Dalakas MC

    更新日期:1995-05-25 00:00:00

  • Induction of oocytic maturation and differentiation: mode of progesterone action.

    abstract::Full-grown amphibian oocytes, arrested in prophase I or meiosis, respond in vitro to progesterone and certain other steroids. They undergo an apparently normal sequence of nuclear maturation and cytoplasmic differentiation, which are necessary precedents for fertilization and embryogenesis. Individual oocytes or popul...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1977.tb29433.x

    authors: Schuetz AW

    更新日期:1977-03-11 00:00:00

  • Immunosuppressive drugs: azathioprine in the treatment of myasthenia gravis.

    abstract::Azathioprine may be tried for treatment of severe myasthenia gravis, in a dose of 2 mg/kg BW. With careful monitoring the side reactions may be controlled. The therapeutic response will occur after a time delay of 4-8 months. About one-third of patients with type II MG (severe, late onset, HLA B8-) will proceed to a c...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1987.tb51327.x

    authors: Matell G

    更新日期:1987-01-01 00:00:00

  • Transcession of DNA from bacteria to human cells in culture: a possible role in oncogenesis.

    abstract::The human organism is continuously in close contact with microorganisms, especially bacteria. In the present work, by means of a real-time polymerase chain reaction (PCR) technique, we looked for the presence of a distinct bacterial gene in human cells. To this end, we cultured a human cell line, HL60, in a supernatan...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1318.030

    authors: Anker P,Zajac V,Lyautey J,Lederrey C,Dunand C,Lefort F,Mulcahy H,Heinemann J,Stroun M

    更新日期:2004-06-01 00:00:00

  • Plants contain a high number of proteins showing sequence similarity to the animal SUV39H family of histone methyltransferases.

    abstract::The SET domain, first identified within and named after proteins encoded by three Drosophila genes [Su(var)3-9, E(z), and Trithorax], is recognized as a signature motif for histone methyltransferases that are involved in epigenetic processes. The SUV39H family of SET domain proteins methylate specifically the residue ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1329.077

    authors: Zhao Z,Shen WH

    更新日期:2004-12-01 00:00:00

  • Results of long-term experimental studies on the carcinogenicity of formaldehyde and acetaldehyde in rats.

    abstract::Formaldehyde was administered for 104 weeks in drinking water supplied ad libitum at concentrations of 1500, 1000, 500, 100, 50, 10, or 0 mg/L to groups of 50 male and 50 female Sprague-Dawley rats beginning at seven weeks of age. Control animals (100 males and 100 females) received tap water only. Acetaldehyde was ad...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2002.tb04926.x

    authors: Soffritti M,Belpoggi F,Lambertin L,Lauriola M,Padovani M,Maltoni C

    更新日期:2002-12-01 00:00:00

  • Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8.

    abstract::Inflammation plays a key role in excessive bone loss in conditions such as rheumatoid arthritis and periodontitis. An important paradigm in immunology is that inflammatory factors activate feedback inhibition mechanisms to restrain inflammation and limit associated tissue damage. We hypothesized that inflammatory fact...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2011.06217.x

    authors: Ivashkiv LB,Zhao B,Park-Min KH,Takami M

    更新日期:2011-11-01 00:00:00

  • Intracellular and extracellular calcium ions in transmitter release at the neuromuscular synapse.

    abstract::The theme of this presentation has been to show that the control of transmitter release at the neuromuscular synapse is achieved by extracellular and intracellular calcium. For the fast information transfer represented by the end-plate potential, the electrochemical gradient for calcium across the presynaptic membrane...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1978.tb41983.x

    authors: Rahamimoff R,Erulkar SD,Lev-Tov A,Meiri H

    更新日期:1978-04-28 00:00:00

  • Effects of testosterone on cognitive and brain aging in elderly men.

    abstract::Older age is associated with functional declines throughout the body, including some aspects of cognitive performance. While dementia develops in only some elderly individuals, declines in cognitive functioning have an impact on daily living for many others. There are individual differences in age-related cognitive ch...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1196/annals.1323.014

    authors: Moffat SD

    更新日期:2005-12-01 00:00:00

  • Recent discoveries of new hantaviruses widen their range and question their origins.

    abstract::Hantaviruses belong to the Bunyaviridae family. While usually hosted by wild mammals, they are potentially pathogenic for humans, and several serologically distinct groups associated with different syndromes have been identified. Yet, investigations have mostly been conducted where human infections by hantaviruses con...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1428.064

    authors: Henttonen H,Buchy P,Suputtamongkol Y,Jittapalapong S,Herbreteau V,Laakkonen J,Chaval Y,Galan M,Dobigny G,Charbonnel N,Michaux J,Cosson JF,Morand S,Hugot JP

    更新日期:2008-12-01 00:00:00

  • Epigenetic regulatory mechanisms during preimplantation embryo development.

    abstract::Within the past few years, developmental scientists have switched their attention from the study of DNA sequencing to the epigenetic state of the genome. Studying epigenetics could present the key to understanding gene expression changes without altering the basic structure of DNA. For example, the blastocyst, trophec...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2010.05937.x

    authors: Palini S,De Stefani S,Scala V,Dusi L,Bulletti C

    更新日期:2011-03-01 00:00:00

  • Involvement of adenylyl cyclase signaling mechanism in insulin and IGF-I coregulation of fundamental cell processes.

    abstract::The discovery of the adenylyl cyclase signaling mechanism (ACSM) of insulin and related peptides allows for advancing the hypothesis of its participation in regulatory action on cell growth, apoptosis, and metabolism. The following evidences were obtained: (1) The order of efficiency of insulin and IGF-I growth-promot...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1196/annals.1327.081

    authors: Pertseva MN

    更新日期:2005-04-01 00:00:00

  • The depressed suicidal patient. Assessment and treatment.

    abstract::Depressive disorders are associated with significant psychosocial impairment and disability. Depression should be thoroughly evaluated, as should current and past suicidality and potential risk factors for suicide. Mortality by suicide characterizes the course of major affective disorders in approximately 15% of those...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2001.tb05795.x

    authors: Nemeroff CB,Compton MT,Berger J

    更新日期:2001-04-01 00:00:00

  • Changes in body fluids during endurance rowing training.

    abstract::The aim of this study was to investigate the influence of long-lasting, extensive rowing training on body fluids in 12 experienced rowers (23.3 +/- 6.3 years, 188.7 +/- 5.9 cm, 82.0 +/- 10.8 kg, body mass index [BMI] 23.7 +/- 2.1). All rowers had a light traditional breakfast about 3 h before the training. The subject...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2000.tb06481.x

    authors: Jürimäe J,Jürimäe T,Pihl E

    更新日期:2000-05-01 00:00:00

  • The significance of Manduca sexta allatostatin in the tomato moth Lacanobia oleracea.

    abstract::The nature and regulation of juvenile hormone (JH) biosynthesis have been investigated in isolated corpora allata (CA) of adult males and females, and larvae of the tomato moth Lacanobia oleracea (Noctuidae). Larval CA (Vth day 1 to VIth day 1) appear to synthesize JH at very low rates (< 0.5 fmol/pr/h). This synthesi...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1999.tb07903.x

    authors: Audsley N,Weaver RJ,Edwards JP

    更新日期:1999-01-01 00:00:00

  • Nicotinic acetylcholine receptors on vagal afferent neurons.

    abstract::Nicotinic acetylcholine receptors (nAChRs) play an important role in various processes involved in regulating systemic blood pressure. These receptors are expressed at excitatory cholinergic synapses between sympathetic preganglionic neurons and postganglionic sympathetic neurons and link the integrative activities of...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2001.tb03670.x

    authors: Cooper E

    更新日期:2001-06-01 00:00:00

  • Prevalence of Salmonella species in various raw meat samples of a local market in Kathmandu.

    abstract::A cross-sectional study of raw meat samples from the local meat market of Kathmandu Metropolitan City was carried out during September 2002 to May 2003 with special emphasis on isolation and identification of Salmonella bacteria. A total of 123 raw meat samples (55 chicken, 37 buffalo, and 31 goat) were collected and ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1373.031

    authors: Maharjan M,Joshi V,Joshi DD,Manandhar P

    更新日期:2006-10-01 00:00:00

  • Vaccines developed for H5 highly pathogenic avian influenza in China.

    abstract::Since the first detection of highly pathogenic H5N1 avian influenza virus from sick goose in Guangdong province in China in 1996, scientists in China started to develop vaccines for avian influenza pandemic preparedness. An H5N2 inactivated vaccine was produced from a low pathogenic virus, A/turkey/England/N-28/73, an...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1373.022

    authors: Qiao C,Tian G,Jiang Y,Li Y,Shi J,Yu K,Chen H

    更新日期:2006-10-01 00:00:00