Transcession of DNA from bacteria to human cells in culture: a possible role in oncogenesis.

Abstract:

:The human organism is continuously in close contact with microorganisms, especially bacteria. In the present work, by means of a real-time polymerase chain reaction (PCR) technique, we looked for the presence of a distinct bacterial gene in human cells. To this end, we cultured a human cell line, HL60, in a supernatant in which bacteria (Bacillus subtilis) had been grown. A transient transcession of bacterial DNA into the human cells was observed.

journal_name

Ann N Y Acad Sci

authors

Anker P,Zajac V,Lyautey J,Lederrey C,Dunand C,Lefort F,Mulcahy H,Heinemann J,Stroun M

doi

10.1196/annals.1318.030

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

195-201

eissn

0077-8923

issn

1749-6632

pii

1022/1/195

journal_volume

1022

pub_type

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