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Reserpine and breast cancer in women in germany.

Abstract：

:Exposure to reserpine was compared in 181 women interviewed prior to biopsy and found to have breast cancer and 307 women found to have a benign disorder of the breast. The age-adjusted relative risk of breast cancer in those who had taken reserpine was 0.6 (95% confidence limits: 0.4 and 1.1). When the 181 breast cancer patients were compared with a second control group of 101 women with a benign condition requiring surgery, the relative risk was 0.9 (95% confidence limits: 0.4 and 1.7). Neither long-term exposure nor its timing, gave any evidence of an association with breast cancer. The findings in this study do not support the hypothesis that rauwolfia derivatives initiate or promote breast cancer.

journal_name

Eur J Clin Pharmacol

journal_title

European journal of clinical pharmacology

authors

Kewitz H,Jesdinsky HJ,Schröter PM,Lindtner E

doi

10.1007/BF00562896

subject

Has Abstract

pub_date

1977-01-03 00:00:00

pages

79-83

issue

2

eissn

0031-6970

issn

1432-1041

journal_volume

11

pub_type

杂志文章

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