当前位置： SCI文献检索 > EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY期刊下所有文献 > A preliminary study of the effects of prepeated doses of clobazam on aspects of performance, arousal and behaviour in a group of anxiety rated volunteers.

A preliminary study of the effects of prepeated doses of clobazam on aspects of performance, arousal and behaviour in a group of anxiety rated volunteers.

Abstract：

:Repeated doses of a 1,5 benzodiazepine, clobazam, were administered to a group of consenting volunteers. Performance on a psychomotor performance task was not impaired by repeated doses of the drug. Subjective assessments of anxiety were reduced commensurate with an increase in the level of cortical integration, measured via critical flicker fusion thresholds, suggesting that the anxiolytic activity of the drug is related to its effect on arousal. Important differences were found between the responses of high and low anxiety subjects on objective measures of performance and arousal and on self-completion analogue rating scales.

journal_name

Eur J Clin Pharmacol

journal_title

European journal of clinical pharmacology

authors

Hindmarch I

doi

10.1007/BF00644961

subject

Has Abstract

pub_date

1979-08-01 00:00:00

pages

17-21

issue

1

eissn

0031-6970

issn

1432-1041

journal_volume

16

pub_type

杂志文章

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