Abstract:
:In the present study 27 post-myocardial infarction patients were treated with Persantin capsules (Depot-Kapseln, sustained release form), containing 200 mg dipyridamole, b.i.d. over a period of 3 weeks. Baseline levels for plasma beta-thromboglobulin (BTG), platelet factor 4 (PF4), and serum thromboxane B2 (TXB2) were obtained on day 0 and subsequently on days 1, 3, 5, 7, 14 and 21. The baseline levels for plasma BTG and PF4 as well as for serum TXB2 significantly exceeded those for a control group consisting of healthy subjects. The plasma values for BTG and PF4 remained unchanged during the whole study period. During the first week of study the levels for serum X TXB2 were unchanged; however, on days 14 and 21 the means for TXB2 dropped significantly. There is experimental work to suggest that dipyridamole may exert an inhibitory effect on platelet thromboxane biosynthesis. The present results support this concept.
journal_name
Eur Heart Jjournal_title
European heart journalauthors
Safai-Kutti S,Kutti J,Vedin A,Wilhelmsson Cdoi
10.1093/oxfordjournals.eurheartj.a061891subject
Has Abstractpub_date
1985-06-01 00:00:00pages
468-72issue
6eissn
0195-668Xissn
1522-9645journal_volume
6pub_type
杂志文章abstract::In single vessel disease angioplasty can replace surgery in the majority of patients. In cases of recurrence at the site of angioplasty or in the case of progression elsewhere, a second intervention can be performed. Thus, in the majority of patients surgery can be replaced; in the minority it can be delayed. In patie...
journal_title:European heart journal
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更新日期:1987-09-01 00:00:00
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journal_title:European heart journal
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doi:10.1093/eurheartj/10.suppl_e.2
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journal_title:European heart journal
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doi:10.1093/oxfordjournals.eurheartj.a059838
更新日期:1991-10-01 00:00:00
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journal_title:European heart journal
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doi:10.1016/s0195-668x(03)00385-3
更新日期:2003-09-01 00:00:00
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更新日期:1991-09-01 00:00:00
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journal_title:European heart journal
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更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a060386
更新日期:1994-01-01 00:00:00
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journal_title:European heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-04-01 00:00:00
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更新日期:2018-07-01 00:00:00
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更新日期:2005-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1053/euhj.1997.0858
更新日期:1998-05-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章,评审
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更新日期:1995-11-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2012-09-01 00:00:00
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更新日期:2012-08-01 00:00:00
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更新日期:2006-04-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章,评审
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更新日期:2013-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:1991-09-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:1998-02-01 00:00:00
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journal_title:European heart journal
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doi:10.1093/eurheartj/ehi556
更新日期:2005-12-01 00:00:00
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更新日期:2012-03-01 00:00:00