Abstract：
:In this study, we observed mitotic preosteoblasts that have the structural features of osteoblasts in the primary spongiosa of the rat mandibular condyle. The rough endoplasmic reticulum and the Golgi apparatus showed remarkable disorganization during mitosis. The Golgi saccules were replaced by groups of large vacuoles and small vesicles. The cisternae of the rough endoplasmic reticulum also were vacuolized. Since this disorganization occurred in conjunction with the formation of the mitotic spindle, it is probably related to the changes of the microtubular cytoskeleton. Further, secretory granules were arrayed along the mitotic spindle microtubules at the metaphase, and concentrated around the midbody at the telophase. These findings indicate a close relationship exists between secretory granules and microtubules.
journal_name
Bonejournal_title
Boneauthors
Shibata S,Baba O,Sakamoto Y,Ohsako M,Yamashita Y,Ichijo Tdoi
10.1016/8756-3282(93)90253-7subject
Has Abstractpub_date
1993-01-01 00:00:00pages
35-40issue
1eissn
8756-3282issn
1873-2763pii
8756-3282(93)90253-7journal_volume
14pub_type
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