Different phosphorylation rates among vertebrate cone visual pigments with different spectral sensitivities.

abstract：:The causative agent of Lyme disease, Borrelia burgdorferi, requires shifts in gene expression to undergo its natural enzootic cycle between tick and vertebrate hosts. mRNA decay mechanisms play significant roles in governing gene expression in other bacteria, but are not yet characterized in B. burgdorferi. RNase III ...

journal_title：Biochemical and biophysical research communications

authors： Snow S,Bacon E,Bergeron J,Katzman D,Wilhelm A,Lewis O,Syangtan D,Calkins A,Archambault L,Anacker ML,Schlax PJ

更新日期：2020-08-20 00:00:00

abstract：:Two-dimensional polyacrylamide gel electrophoresis (2-DE) profiles of human lung squamous carcinoma tissue and paired surrounding normal bronchial epithelial tissue were compared. Selected differential protein-spots were identified with peptide mass fingerprinting based on matrix-assisted laser desorption/ionization t...

journal_title：Biochemical and biophysical research communications

authors： Li C,Chen Z,Xiao Z,Wu X,Zhan X,Zhang X,Li M,Li J,Feng X,Liang S,Chen P,Xie JY

更新日期：2003-09-12 00:00:00

abstract：:Endothelin-1 (ET-1) is a 21-amino acid vasoactive peptide produced from a 39-amino acid biologically inactive peptide, big ET-1, by the action of endothelin-converting enzyme-1 (ECE-1). We investigated gastric mucosal expression of ECE-1 during a 16 h course of inflammatory responses associated with gastric mucosal in...

journal_title：Biochemical and biophysical research communications

authors： Slomiany BL,Slomiany A

更新日期：2000-03-16 00:00:00

abstract：:The acidic leucine-rich nuclear phosphoprotein 32B (ANP32B) is a member of a conserved superfamily of nuclear proteins whose functions are largely unknown. In our previous work, ANP32B was identified as a novel direct substrate for caspase-3 and acted as a negative regulator for leukemic cell apoptosis. In this work, ...

journal_title：Biochemical and biophysical research communications

authors： Yu Y,Shen SM,Zhang FF,Wu ZX,Han B,Wang LS

更新日期：2012-07-13 00:00:00

abstract：:Glycogen-storage disease type II (GSD II, acid maltase deficiency, Pompe's disease) is caused by defects in the lysosomal acid alpha-glucosidase (GAA) gene. Clinically, patients with the severe infantile form of GSD II have muscle weakness and cardiomyopathy eventually leading to death before the age of two years. Pat...

journal_title：Biochemical and biophysical research communications

authors： Nicolino M,Puech JP,Letourneur F,Fardeau M,Kahn A,Poenaru L

更新日期：1997-06-09 00:00:00

abstract：:We discovered recently that Parkinsonism-associated DJ-1 and its bacterial homologs function as protein deglycases that repair glyoxal- and methylglyoxal-glycated proteins. Protein glycation levels are 2- to 10-fold increased in deglycase-depleted cells, and deglycase mutants display up to 500-fold loss of viability i...

journal_title：Biochemical and biophysical research communications

authors： Richarme G,Dairou J

更新日期：2017-01-29 00:00:00

abstract：:Androgen receptor (AR) recognizes and binds to 15-bp palindromic androgen response element (ARE) sequences with high affinity in vitro, which consist of two hexameric half-sites arranged as inverted repeats with a 3-bp spacer. Although a few near-consensus ARE sequences have been actually identified in the transcripti...

journal_title：Biochemical and biophysical research communications

authors： Horie-Inoue K,Bono H,Okazaki Y,Inoue S

更新日期：2004-12-24 00:00:00

abstract：:Dexamethasone (Dex) causes osteoblast cell injuries. In the present research, we tested the potential effect of SC79, a novel and specific Akt activator, against Dex in osteoblasts. In primary murine osteoblasts and osteoblastic MC3T3-E1 cells, pretreatment with SC79 significantly attenuated Dex-induced cell death. Fu...

journal_title：Biochemical and biophysical research communications

authors： Li ST,Chen NN,Qiao YB,Zhu WL,Ruan JW,Zhou XZ

更新日期：2016-10-07 00:00:00

abstract：:Defects in neurogenesis and neuronal differentiation in the fetal brain of Down syndrome (DS) patients lead to the apparent neuropathological abnormalities and contribute to the phenotypic characters of mental retardation, and premature development of Alzheimer's disease, those being the most common phenotype in DS. I...

journal_title：Biochemical and biophysical research communications

authors： Wang CC,Kadota M,Nishigaki R,Kazuki Y,Shirayoshi Y,Rogers MS,Gojobori T,Ikeo K,Oshimura M

更新日期：2004-02-06 00:00:00

abstract：:Nearly complete cDNA clones for human aldolase A mRNA were isolated from human liver cDNA library and the nucleotide sequence determined. Using the cDNA clone as a probe the length of human aldolase A mRNAs, isolated from the skeletal muscle, liver and placenta tissues, was measured by RNA blotting and estimated to be...

journal_title：Biochemical and biophysical research communications

authors： Sakakibara M,Mukai T,Hori K

更新日期：1985-08-30 00:00:00

abstract：:Human serum albumin (HSA) patterns have been successfully fabricated for the deposition of lipid bilayer, 1,2-dimyristoyl-sglycerophosphate (DMPA), by making use of the micro-contact printing (microCP) technique and liposome fusion. Confocal laser scanning microscopy (CLSM) results indicate that lipid bilayer has been...

journal_title：Biochemical and biophysical research communications

authors： Zhang X,He Q,Cui Y,Duan L,Li J

更新日期：2006-10-27 00:00:00

abstract：:This report examines the balance of positive and negative adipogenic factors in a line of immortalized 243 embryonic fibroblasts that undergo spontaneous preadipocyte differentiation. Control of adipogenesis reflects the interplay of factors that promote or inhibit expression of C/EBPalpha and PPARgamma. The 243 cells...

journal_title：Biochemical and biophysical research communications

authors： Bennett CN,Hodge CL,MacDougald OA,Schwartz J

更新日期：2003-02-28 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been reported as essential regulators in human cancers, including lung adenocarcinoma (LUAD). In the present study, we found that lncRNA long intergenic non-protein coding RNA 467 (LINC00467) was expressed higher in TCGA LUAD samples and predicted poor prognosis in LUAD patients. Hi...

journal_title：Biochemical and biophysical research communications

authors： Yang J,Liu Y,Mai X,Lu S,Jin L,Tai X

更新日期：2019-06-18 00:00:00

abstract：:MDP, a synthetic muramyl dipeptide, is capable of increasing the primary in vitro antibody response, to sheep erythrocytes, of purified B cells restored with a monokine and helper T cell factors, including Interleukin 2 and the late-acting T cell replacing factor (TRF). First, the possibility that the adjuvanticity of...

journal_title：Biochemical and biophysical research communications

authors： Souvannavong V,Adam A

更新日期：1984-11-30 00:00:00

abstract：:Osteoporosis is a common bone disorder with adverse effects on oral osseointegration, and the effects of metformin on bone metabolism have received increasing attention. The aim of the present study was to test the hypothesis that metformin promoted osteogenesis of bone mesenchymal stem cells (BMSCs) and osseointegrat...

journal_title：Biochemical and biophysical research communications

authors： Lin J,Xu R,Shen X,Jiang H,Du S

更新日期：2020-10-15 00:00:00

abstract：:Sf9 cells infected with the recombinant mouse CaMKII-alpha (Ca2+/calmodulin dependent kinase II) baculovirus expressed 12-15 mg of MCaMKII-alpha per liter of cells. Approximately 50% of the MCaMKII-alpha activity could be purified using a CaM-Sepharose affinity column. The purified MCaMKII-alpha had a M(rapp) of 50 kD...

journal_title：Biochemical and biophysical research communications

authors： Brickey DA,Colbran RJ,Fong YL,Soderling TR

更新日期：1990-12-14 00:00:00

abstract：:Recently, we reported that Lumbricusin, an antimicrobial peptide isolated from earthworm Lumbricus terrestris, enhanced neuronal proliferation and ameliorated motor dysfunction and dopaminergic neurodegeneration. Accumulating evidence suggests that neurodegeneration is the primary pathological feature of acute or chro...

journal_title：Biochemical and biophysical research communications

authors： Seo M,Lee JH,Baek M,Kim MA,Ahn MY,Kim SH,Yun EY,Hwang JS

更新日期：2017-08-26 00:00:00

abstract：:We have obtained the optimized geometrical structure of 2-(1-carboxy-1-hydroxyethyl)-3,4-dimethylthiazolium dipolar ion and investigated its geometric and electric changes during decarboxylation process by the MNDO-PM3 method, a molecular orbital method. The salient features of the optimized structure are that the dih...

journal_title：Biochemical and biophysical research communications

authors： Nakajima Y,Sakagishi Y,Shiibashi M,Suzuki Y,Kato H

更新日期：1993-08-31 00:00:00

abstract：:3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.3.4.) activity and cell membrane fluidity measured by fluorescence polarization using 1,6 diphenyl, 1,3,5-hexatriene as fluorescent probe have been concomitantly examined in HTC hepatoma cells, both in relation to growth rate and in response to treatment with h...

journal_title：Biochemical and biophysical research communications

authors： Richert L,Castagna M,Beck JP,Rong S,Luu B,Ourisson G

更新日期：1984-04-16 00:00:00

abstract：:Helodermin is a peptide from the venom of the lizard Heloderma suspectum (Gila Monster) showing a high degree of sequence similarity with VIP, PHI and secretin in its N-terminal moiety. The present data support the presence of peptide(s) closely related to helodermin in the brain, gut and salivary glands of rat. In ou...

journal_title：Biochemical and biophysical research communications

authors： Robberecht P,De Graef J,Woussen MC,Vandermeers-Piret MC,Vandermeers A,De Neef P,Cauvin A,Yanaihara C,Yanaihara N,Christophe J

更新日期：1985-07-16 00:00:00

abstract：:Amino acid transporter plays an important role in regulating mTOR signaling pathway. This study investigated the effects of reduced dietary protein levels on amino acid transporters and mTOR signaling pathway. A total of 54 weaning pigs were randomly allocated into a 3 × 3 factorial design, followed by slaughtering th...

journal_title：Biochemical and biophysical research communications

authors： Wang D,Wan X,Peng J,Xiong Q,Niu H,Li H,Chai J,Jiang S

更新日期：2017-04-01 00:00:00

abstract：:HIV-1 Vpr is a protein with multiple functions. It has been suggested that such pleiotropic effects by a viral protein may be mediated by its association with viral and cellular proteins or through modulation of expression of specific cellular genes. To address this, we used cDNA microarray techniques to analyze the r...

journal_title：Biochemical and biophysical research communications

authors： Janket ML,Manickam P,Majumder B,Thotala D,Wagner M,Schafer EA,Collman RG,Srinivasan A,Ayyavoo V

更新日期：2004-02-20 00:00:00

abstract：:G13 belongs to the G12-subfamily of heterotrimeric regulatory G-proteins. Employing specific antibodies, we isolated G alpha 13 from bovine brain by a four-step purification protocol combining conventional and affinity chromatography. The use of ethylene glycol as a protective agent influenced the elution properties o...

journal_title：Biochemical and biophysical research communications

authors： Harhammer R,Nürnberg B,Spicher K,Schultz G

更新日期：1994-10-28 00:00:00

abstract：:Malaria, a disease accounting for more than one million deaths per year, is caused by intraerythrocytic growth of Plasmodia. Parasitemia may be blunted by suicidal erythrocyte death or eryptosis, which is characterized by cell shrinkage and phosphatidylserine exposure. Triggers of eryptosis include lead nitrate (Pb(NO...

journal_title：Biochemical and biophysical research communications

authors： Koka S,Huber SM,Boini KM,Lang C,Föller M,Lang F

更新日期：2007-11-23 00:00:00

abstract：:Binding of ATP, but not of ADP, activates Escherichia coli DnaA protein for replicational initiation of the chromosome. To elucidate this switching mechanism, we used the affinity-labeling agent ATP-pyridoxal, which forms a covalent bond with the Lys residue located at or near the gamma-phosphate of ATP. ATP-pyridoxal...

journal_title：Biochemical and biophysical research communications

authors： Kubota T,Ito Y,Sekimizu K,Tagaya M,Katayama T

更新日期：2001-11-16 00:00:00

abstract：:Despite the fact that the phosphorylation-mediated regulation of L-type Ca channels is viewed as a model of ion channel regulation, much remains to be learned about the protein phosphorylation and dephosphorylation reactions that underlie the regulation of the channels. The channel isoform most well studied biochemica...

journal_title：Biochemical and biophysical research communications

authors： Zhao XL,Gutierrez LM,Chang CF,Hosey MM

更新日期：1994-01-14 00:00:00

abstract：:Trilobolide and 2,5-di(tert-butyl)-1,4-benzohydroquinone (BHQ) are potent inhibitors of the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum. Desoxytrilobolide and 2,5-di(tert-butyl)-1,4-diacetylphenol (acetyl-BHQ) have much lower potencies than their parent compounds and 2,5-di(tert-butyl)-1,4-benzoquinone (BQ...

journal_title：Biochemical and biophysical research communications

authors： Wictome M,Holub M,East JM,Lee AG

更新日期：1994-03-15 00:00:00

abstract：:Upon binding of a Wnt to its receptor, GSK3beta is inhibited through an unknown mechanism involving Dishevelled (Dsh), resulting in the dephosphorylation and stabilization of beta-catenin, which translocates to the nucleus and interacts with Lef/Tcf transcription factors to activate target gene expression. Axin is a s...

journal_title：Biochemical and biophysical research communications

authors： Jho Eh,Lomvardas S,Costantini F

更新日期：1999-12-09 00:00:00

abstract：:In vertebrate cells, DNA double-strand breaks are efficiently repaired by homologous recombination or nonhomologous end-joining (NHEJ). The latter pathway relies on Ku (the Ku70/Ku86 heterodimer), DNA-PKcs, Artemis, Xrcc4, and DNA ligase IV (Lig4). Here, we show that a human pre-B cell line nullizygous for Lig4 exhibi...

journal_title：Biochemical and biophysical research communications

authors： Adachi N,Iiizumi S,So S,Koyama H

更新日期：2004-06-11 00:00:00

abstract：:Pre-treatment of neutrophils with either pertussis or cholera toxins does not inhibit neutrophil activation by surface bound IgG. In contrast, pretreatment with the phorbol ester, phorbol myristate acetate, results in a dose dependent inhibition of degranulation by surface bound IgG. This inhibition is similar to that...

journal_title：Biochemical and biophysical research communications

authors： Blackburn WD Jr,Heck LW

更新日期：1989-11-15 00:00:00