Applications of flow cytometric DNA analysis to diagnostic cytology.

Abstract:

:Flow cytometry is a rapid method for measuring DNA content. Its high sensitivity and specificity in detecting transitional cell carcinomas in bladder washings should make it a routinely applied adjunct to cytology once universal laboratory standards are firmly established. Diagnostic and prognostic information on solid tumors can be obtained at least as reliably on fine-needle aspirations as on surgically resected specimens. At the present time, the sensitivity of FCM in the evaluation of effusions, peritoneal washings, and CSF is relatively low, and although in some cases malignant cells in these specimens that are missed by conventional cytology are detected by FCM, the number of such cases is small. Investigation continues into the application of FCM to the screening of cervical specimens.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Cibas ES

doi

10.1002/dc.2840130219

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

166-71

issue

2

eissn

8755-1039

issn

1097-0339

journal_volume

13

pub_type

杂志文章,评审
  • Fine-needle aspiration cytology of adenoid (acantholytic) squamous-cell carcinoma.

    abstract::Adenoid squamous-cell carcinoma (ASCCa) is an uncommon cancer which occurs most frequently in the skin of the head and neck region of elderly, sun-exposed individuals. Histologically, ASCCa is characterized by gland-like, "adenoid" cell groups with a central, detached acantholytic cellular component and an intact peri...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840120218

    authors: Dodd LG

    更新日期:1995-03-01 00:00:00

  • The expanding role of cytopathology in the diagnosis of HPV-related squamous cell carcinoma of the head and neck.

    abstract::Confirmation of human papillomavirus (HPV) as a causative agent for a subset of biologically and clinically distinct squamous cell carcinomas of the head and neck (HNSCC) has resulted in a growing need and expectation for HPV testing of head and neck cancers. At the same time, opportunities to obtain tissue samples fo...

    journal_title:Diagnostic cytopathology

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    doi:10.1002/dc.23014

    authors: Holmes BJ,Westra WH

    更新日期:2014-01-01 00:00:00

  • Significance of atypia in pancreatic and bile duct brushings: follow-up analysis of the categories atypical and suspicious for malignancy.

    abstract::Brushing cytology is frequently utilized for the investigation of pancreatic and biliary strictures but is associated with low diagnostic sensitivity. The Papanicolaou Society of Cytopathology has presented a system for diagnostic classification which includes the categories benign, atypical, suspicious for malignancy...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23035

    authors: Chadwick BE,Layfield LJ,Witt BL,Schmidt RL,Cox RN,Adler DG

    更新日期:2014-04-01 00:00:00

  • Application of immunostaining for muscle specific actin in detection of myoepithelial cells in breast fine-needle aspirates.

    abstract::Myoepithelial cells play an important role in the interpretation of breast fine-needle aspiration biopsy, since these cells are believed to be a component of a benign process in breast lesions. Myoepithelial cells are usually easy to recognize, however, other cells can morphologically simulate myoepithelial cells and ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840130115

    authors: Masood S,Lu L,Assaf-Munasifi M,McCaulley K

    更新日期:1995-07-01 00:00:00

  • Needle aspiration cytology, immunocytochemistry, and electron microscopic study of unusual pancreatic carcinoma with pleomorphic giant cells.

    abstract::Needle aspiration cytology, immunocytochemistry, and electron-microscopic findings are presented in three cases of an unusual pancreatic carcinoma in which pleomorphic giant cells formed an integral part of the tumour. All three patients were elderly males (age range 66-83 years) and had pancreatic masses. Notable cyt...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840080513

    authors: Gupta RK,Wakefield SJ

    更新日期:1992-01-01 00:00:00

  • Sensitivity of fine-needle aspiration for papillary carcinoma of the thyroid correlates with tumor size.

    abstract::Fine-needle aspiration (FNA) of the thyroid for papillary carcinomas is highly sensitive. We sought to determine if the sensitivity of FNA for papillary carcinoma is correlated with the size of the tumor. We reviewed the results of thyroid resections for the last 12 years and correlated the findings with clinical and ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21411

    authors: Renshaw AA

    更新日期:2011-07-01 00:00:00

  • Fine-needle aspiration cytology of ameloblastoma and malignant ameloblastoma: a study of 12 cases.

    abstract::Ameloblastoma is an odontogenic tumor with aggressive biological behavior, high recurrence rate, and a complex microscopic appearance with many different histologic patterns. Primary ameloblastoma is also described in extragnathic locations. Because of its wide morphologic spectrum, which is mirrored also in cytologic...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21823

    authors: Klapsinou E,Stavros A,Smaragda A,Despoina P,Dimitra D

    更新日期:2013-03-01 00:00:00

  • Aspiration cytodiagnosis of amyloid from vitreous fluid.

    abstract::Amyloidosis of the vitreous body is a rare disorder that causes progressive visual loss. In this report, a 36-yr-old female with familial amyloidosis is described in whom a progressive reduction of vision in both eyes over the last 4 yr was ascribed to vitreous opacities due to amyloid. A left pars plana vitrectomy wa...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10090

    authors: Gupta RK,Wakefield J,Halliwell T,Foo K,Lallu S,Naran S,Fauck R

    更新日期:2002-05-01 00:00:00

  • Fine-needle aspiration cytology in azoospermic males.

    abstract::Bilateral testicular fine-needle aspiration cytology (FNAC) was performed in 100 males, including 10 controls with normal fertility and 90 infertile azoospermic males. The various seminiferous tubular cells were easily identified in smears. It was possible to give a cytological diagnosis in histologic terms by analysi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840070103

    authors: Rajwanshi A,Indudhara R,Goswami AK,Radhika S,Das A,Sharma SK,Vaidyanathan S,Datta BN

    更新日期:1991-01-01 00:00:00

  • Fine needle aspiration of secondary synovial sarcoma of the thyroid gland.

    abstract::Synovial sarcomas (SS) of the head and neck region are extremely rare and arise in only 5% of cases. We present a case of secondary SS of the thyroid originally diagnosed as medullary carcinoma on fine needle aspiration (FNA). A 41-year-old man presented with several weeks of dysphonia and a left thyroid mass. FNA of ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23327

    authors: Murro D,Slade JM,Syed S,Gattuso P

    更新日期:2015-11-01 00:00:00

  • Polymicrobial lung infection in postrenal transplant recipient diagnosed by fine-needle aspiration cytology.

    abstract::Tuberculous and fungal infections are among the non-neoplastic lesions of the lung, in which fine-needle aspiration cytology (FNAC) has proven to be a useful technique in both immunocompromised and immunocompetent patients. The presence of polymicrobial infection in a renal transplant recipient is documented in the li...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21198

    authors: Duggal R,Rajwanshi A,Gupta N,Lal A,Singhal M

    更新日期:2010-04-01 00:00:00

  • Seriate cytology vs molecular analysis of peritoneal washing to improve gastric cancer cells detection.

    abstract:BACKGROUND:Intraperitoneal malignant cells detection in patients with gastric cancer is associated with a significant decrease in overall survival. The overall accuracy of cytological examination of peritoneal lavages, however, is quite low, and intraperitoneal recurrence has been observed even in patients with negativ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24165

    authors: Taffon C,Giovannoni I,Mozetic P,Capolupo GT,La Vaccara V,Cinque C,Caricato C,Rainer A,Zelano G,Crescenzi A

    更新日期:2019-07-01 00:00:00

  • Scrape cytology of the ovaries: potential role in intraoperative consultation of ovarian lesions.

    abstract::Intraoperative diagnosis of ovarian lesions can be achieved by gross examination with the help of frozen sections and/or cytologic examination. Various cytologic techniques, including imprint, fine-needle aspiration, and scrape, may be used. In this study, we evaluated the application of scrape cytology in the diagnos...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10273

    authors: Khunamornpong S,Siriaunkgul S

    更新日期:2003-05-01 00:00:00

  • Diagnosis of peripheral T-cell lymphoma by fine-needle aspiration biopsy: a cytomorphologic and immunophenotypic approach.

    abstract::The diagnosis of T-cell lymphomas by fine-needle aspiration biopsies (FNAB) is extremely difficult. This is mainly due to the rarity of the disease, the morphologic similarity to reactive lymphadenopathy, and the difficulty in identifying abnormal T-cell antigen expression. We studied FNAB of histologically proven T-c...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/1097-0339(200012)23:6<375::aid-dc2>3.0.co;

    authors: Al Shanqeety O,Mourad WA

    更新日期:2000-12-01 00:00:00

  • Diagnostic value of eosinophils in pleural effusion: a prospective study of 26 cases.

    abstract::Eosinophilic pleural effusions (EPFs), defined as the presence of 10% or more eosinophils in the pleural fluid, are relatively rare. Their diagnostic and prognostic significance, however, remains controversial, as most of the studies are based almost entirely on retrospective case studies. This prospective study exami...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10227

    authors: Matthai SM,Kini U

    更新日期:2003-02-01 00:00:00

  • Cytologic diagnosis of pseudomyxoma peritonei: common and uncommon causes.

    abstract::Pseudomyxoma peritonei (PP) refers to accumulation of mucus in the peritoneal cavity, regardless of cause or pathogenesis. We have reviewed 8 cases of PP diagnosed in our institution over the past 5 years. Pertinent cytologic features include a mucinous background with mesothelial cells and histiocytes. Two cases cont...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0339(199602)14:1<10::AID-DC3>3.

    authors: Pisharodi LR,Bedrossian CW

    更新日期:1996-02-01 00:00:00

  • Fine-needle aspiration of hepatocellular carcinoma: False-negative result due to epithelioid cells.

    abstract::The presence of epithelioid cells in fine-needle aspirations of a liver nodule is rare, but may complicate the diagnosis of the nodule. We report on a case of a liver nodule in hepatitis C cirrhosis. Results of fine-needle aspiration mainly revealed the presence of epithelioid cells, without any recognizable tumor cel...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.1087

    authors: Mourra N,Flejou JF

    更新日期:2001-06-01 00:00:00

  • Nodular fasciitis: spontaneous resolution following diagnosis by fine-needle aspiration.

    abstract::Nodular fasciitis can be histologically mistaken for a sarcoma. Typical cases are less than 5 cm and enlarge rapidly over days or weeks before diagnosis. The natural history of nodular fasciitis is unknown, since the diagnosis is usually based on excised lesions. Fine-needle aspiration of nodular fasciitis has been de...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840090316

    authors: Stanley MW,Skoog L,Tani EM,Horwitz CA

    更新日期:1993-01-01 00:00:00

  • A case of endocervical minimal deviation adenocarcinoma with varicolored cytopathologic features on Pap smear.

    abstract::We report a case of minimal deviation adenocarcinoma (MDA) of the uterine cervix showing varicolored cytopathologic features on Papanicolaou (Pap) smear, which may indicate features suggestive of lobular endocervical glandular hyperplasia (LEGH)-adenocarcinoma sequence. A 57-year-old woman presented with a profuse amo...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23932

    authors: Omori M,Kondo T,Nakazawa K,Shinohara S,Watanabe Y,Fukasawa H,Nakazawa T,Hashi A,Hirata S

    更新日期:2018-08-01 00:00:00

  • Cytological diagnosis of collagenous spherulosis of breast associated with fibroadenoma: report of a case with review of literature.

    abstract::Collagenous spherulosis of the breast is a rare incidental finding frequently associated with other benign lesions of the breast. The estimated incidence of this innocuous condition is only about 0.2% in cytological material. It is of utmost importance to differentiate collagenous spherulosis from its malignant mimics...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.20632

    authors: Gangane N,Joshi D,Anshu.,Shivkumar VB

    更新日期:2007-06-01 00:00:00

  • Two AgNOR counts in fine-needle aspirates of lymphoproliferative disorders compared with acridine orange flow cytometry.

    abstract::Studies have shown that argyrophilic nucleolar organizer region-associated proteins (AgNORs) may correlate with DNA ploidy and/or proliferative activity in neoplastic and non-neoplastic conditions. However, studies have estimated only the mean AgNOR counts. Here we used two AgNOR counts, one of which may correlate wit...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840080208

    authors: Mourad WA,Katz RL,Sembera D,Atkinson EN,el-Naggar AK

    更新日期:1992-01-01 00:00:00

  • Kba.62 and S100 protein expression in cytologic samples of metastatic malignant melanoma.

    abstract::The diagnosis of melanoma can be challenging, especially in metastatic lesions, due to the ability of melanoma cells to morphologically mimic carcinoma, sarcoma and even lymphoma cells. Moreover, melanomas can exhibit negative immunostaining for the melanoma markers HMB-45 and MART-1/Melan-A, often used in the diagnos...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.22948

    authors: Erdag G,Chowdhuri SR,Fetsch P,Erickson D,Hughes MS,Filie AC

    更新日期:2013-10-01 00:00:00

  • Cytopathological features of solitary fibrous tumor of the pleura: a study of 5 cases.

    abstract::Solitary fibrous tumor is a rare lesion of serosal membranes. In a pleural location, it may be confused clinically with a localized mesothelioma or a peripheral lung tumor. A transthoracic needle aspiration can be done to obtain material for a diagnosis in these easily accessible tumors. In the literature, there are o...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199802)18:2<118::aid-dc7>3

    authors: Weynand B,Collard P,Galant C

    更新日期:1998-02-01 00:00:00

  • Isolated lingual cysticercosis: A rare case diagnosed on cytology.

    abstract::Cysticercosis is caused by larval stage of Taenia solium called cysticercus cellulosae. Cysticercosis most commonly infects skeletal muscles, subcutaneous tissues, brain and ocular tissue. On extensive search of literature, only around 64 cases of lingual cysticercosis have been reported till date. We report a case of...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23828

    authors: Pujani M,Hassan MJ,Khan S,Jetley S

    更新日期:2018-03-01 00:00:00

  • Limiting factors for cytopathological diagnosis of high-grade squamous intraepithelial lesions: a cytohistological correlation between findings in cervical smears and loop electrical excision procedure.

    abstract::The present study sought possible factors leading to the cytological diagnosis of atypical squamous cells of uncertain significance (ASCUS) in cases of high-grade squamous intraepithelial lesions (HSIL). Based on retrospective histopathological analysis of loop electrical excision procedure (LEEP) products that diagno...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10035

    authors: Pinto AP AP,Tuon FF,Torres LF,Collaço LM

    更新日期:2002-01-01 00:00:00

  • Diagnostic value of AgNOR method in thyroid cytopathology: correlation with morphometric measurements.

    abstract::A silver staining technique was applied to 51 thyroid smears. The numbers of silver-stained nucleolar organizer regions (AgNORs) were counted, and the mean AgNOR and nuclear area per cell were determined with an image analyzer. The mean AgNOR count per cell was significantly higher in malignant than in benign lesions,...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0339(199603)14:2<140::AID-DC7>3

    authors: Solymosi T,Tóth V,Sápi Z,Bodó M,Gál I,Csanádi L

    更新日期:1996-03-01 00:00:00

  • Immunohistochemical analysis of OTP and NKX6.1 in neuroendocrine tumors of the lung and pancreas.

    abstract:BACKGROUND:Homeobox transcription factors have demonstrated utility in diagnosing neuroendocrine tumors. Orthopedia homeobox protein (OTP) has a well-defined role in embryonic neurodevelopment and has also been described as a prognostic marker in lung neuroendocrine tumors (NET). Additionally, NK6 homeobox-1 (NKX6.1) h...

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    pub_type: 杂志文章

    doi:10.1002/dc.24088

    authors: Yoxtheimer LM,Heymann JJ,Cohen C,Rao RA,Goyal A,Siddiqui MT

    更新日期:2018-12-01 00:00:00

  • Diagnostic impact of core-needle biopsy on fine-needle aspiration of non-Hodgkin lymphoma.

    abstract::We retrospectively reviewed 74 fine-needle aspiration (FNA) cases of presumptive non-Hodgkin lymphoma (NHL). All the cases had cytology and core-needle biopsy and 53 cases had concurrent flow cytometric analysis. FNA (cytology and flow cytometry) and core-needle biopsy were evaluated independently. FNA was diagnostic ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20082

    authors: Gong JZ,Snyder MJ,Lagoo AS,Vollmer RT,Dash RR,Madden JF,Buckley PJ,Jones CK

    更新日期:2004-07-01 00:00:00

  • Update on human polyomavirus BK nephropathy.

    abstract::Polyomavirus BK (BKV) has ebeen identified as the main cause of polyomavirus-associated nephropathy, a major cause of renal allograft failure. Although BKV-associated nephropathy develops in only 2% to 5% of renal transplant recipients, its prognosis when present is very poor, with irreversible graft failure developin...

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    pub_type: 杂志文章,评审

    doi:10.1002/dc.21147

    authors: Cimbaluk D,Pitelka L,Kluskens L,Gattuso P

    更新日期:2009-10-01 00:00:00

  • Bladder-washing cytology of metastatic ovarian granulosa cell tumor.

    abstract::An 86-year-old Caucasian female presented with two weeks history of discomfort discharging urine, occasional hematuria, and suprapubic pain. The patient had a history of left salpingo-oophorectomy for an ovarian tumor, performed four years earlier. Ultrasound showed a solid mass surrounding the orifice of the left ure...

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    pub_type: 杂志文章

    doi:10.1002/dc.10095

    authors: Vodovnik A

    更新日期:2002-06-01 00:00:00