Bladder-washing cytology of metastatic ovarian granulosa cell tumor.

Abstract:

:An 86-year-old Caucasian female presented with two weeks history of discomfort discharging urine, occasional hematuria, and suprapubic pain. The patient had a history of left salpingo-oophorectomy for an ovarian tumor, performed four years earlier. Ultrasound showed a solid mass surrounding the orifice of the left ureter. Bladder washing cytology yielded single, loosely cohesive syncytial aggregates of rather uniform cells. A few discretely grooved nuclei ("coffee bean nuclei") were seen. Histologic examination revealed muscular tissue infiltrated by oval to round cells, arranged in solid and follicular structures. The tumor cells were immunoreactive for estrogen receptor, inhibin, vimentin, and calretinin. The use of antibodies to pancytokeratin, inhibin, estrogen receptor, S-100, calretinin, and chromagranin could help confirm granulosa cell tumor. To my knowledge, there was no previous report on bladder washing cytology of metastatic granulosa cell tumor.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Vodovnik A

doi

10.1002/dc.10095

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

387-8

issue

6

eissn

8755-1039

issn

1097-0339

journal_volume

26

pub_type

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