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Neuraminidase inhibitors for influenza B virus infection: efficacy and resistance.

Abstract：

:Many aspects of the biology and epidemiology of influenza B viruses are far less studied than for influenza A viruses, and one of these aspects is efficacy and resistance to the clinically available antiviral drugs, the neuraminidase (NA) inhibitors (NAIs). Acute respiratory infections are one of the leading causes of death in children and adults, and influenza is among the few respiratory infections that can be prevented and treated by vaccination and antiviral treatment. Recent data has suggested that influenza B virus infections are of specific concern to pediatric patients because of the increased risk of severe disease. Treatment of influenza B is a challenging task for the following reasons: This review presents current knowledge of the efficacy of NAIs for influenza B virus and antiviral resistance in clinical, surveillance, and experimental studies.

journal_name

Antiviral Res

journal_title

Antiviral research

authors

Burnham AJ,Baranovich T,Govorkova EA

doi

10.1016/j.antiviral.2013.08.023

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

520-34

issue

2

eissn

0166-3542

issn

1872-9096

pii

S0166-3542(13)00243-X

journal_volume

100

pub_type

杂志文章,评审

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