Low-frequency stimulation at the troughs of theta-oscillation induces long-term depression of previously potentiated CA1 synapses.

abstract：:Modularity in the central nervous system (CNS), i.e., the brain capability to generate a wide repertoire of movements by combining a small number of building blocks ("modules"), is thought to underlie the control of movement. Numerous studies reported evidence for such a modular organization by identifying invariant m...

journal_title：Journal of neurophysiology

authors： Delis I,Panzeri S,Pozzo T,Berret B

更新日期：2014-02-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) receives a dense serotonergic innervation that modulates photic input to the SCN via serotonin 1B (5-HT1B) presynaptic receptors on retinal glutamatergic terminals. However, the majority of 5-HT1B binding sites in the SCN are located on nonretinal terminals and most axonal terminals i...

journal_title：Journal of neurophysiology

authors： Bramley JR,Sollars PJ,Pickard GE,Dudek FE

更新日期：2005-06-01 00:00:00

abstract：:Hyperreflexia and spasticity are chronic complications in spinal cord injury (SCI), with limited options for safe and effective treatment. A central mechanism in spasticity is hyperexcitability of the spinal stretch reflex, which presents symptomatically as a velocity-dependent increase in tonic stretch reflexes and e...

journal_title：Journal of neurophysiology

authors： Bandaru SP,Liu S,Waxman SG,Tan AM

更新日期：2015-03-01 00:00:00

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00

abstract：:ALS (amyotrophic lateral sclerosis) is an adult-onset and deadly neurodegenerative disease characterized by a progressive and selective loss of motoneurons. Transgenic mice overexpressing a mutated human gene (G93A) coding for the enzyme SOD1 (Cu/Zn superoxide dismutase) develop a motoneuron disease resembling ALS in ...

journal_title：Journal of neurophysiology

authors： Kuo JJ,Schonewille M,Siddique T,Schults AN,Fu R,Bär PR,Anelli R,Heckman CJ,Kroese AB

更新日期：2004-01-01 00:00:00

abstract：:1. To test whether the cerebellum is involved in compensating for orbital nonlinearities, we recorded discharges of saccadic burst neurons in the fastigial oculomotor region (FOR) during both centrifugal and centripetal saccades in two trained macaque monkeys. 2. We also investigated the metrics of centrifugal and cen...

journal_title：Journal of neurophysiology

authors： Ohtsuka K,Sato H,Noda H

更新日期：1994-05-01 00:00:00

abstract：:1. The influence of viewing distance on disparity selectivity was investigated in area V1 of behaving monkeys. While the animals performed a fixation task, cortical cells were recorded extracellularly in the foveal representation of the visual field. Disparity selectivity was assessed by using static random dot stereo...

journal_title：Journal of neurophysiology

authors： Trotter Y,Celebrini S,Stricanne B,Thorpe S,Imbert M

更新日期：1996-11-01 00:00:00

abstract：:Upon prolonged viewing of a sinusoidal grating, the visual system is selectively desensitized to the spatial frequency of the grating, while the sensitivity to other spatial frequencies remains largely unaffected. This technique, known as pattern adaptation, has been so central to the psychophysical study of the mecha...

journal_title：Journal of neurophysiology

authors： Hegdé J

更新日期：2009-10-01 00:00:00

abstract：:While it has been well established that optostatic and optokinetic cues contribute to the perception of vertical, it is unclear how the brain processes their combined presence with the nonvisual vestibular cues. Using a psychometric approach, we examined the percept of vertical in human participants (n = 17) with thei...

journal_title：Journal of neurophysiology

authors： Niehof N,Perdreau F,Koppen M,Medendorp WP

更新日期：2019-08-01 00:00:00

abstract：:Cutaneous application of painful radiant heat laser pulses evokes potentials (laser-evoked potentials) that can be recorded from scalp or intracranial electrodes. We have now tested the hypothesis that the response of thalamic neurons to a cutaneous laser stimulus occurs at latencies predicted by the conduction delay ...

journal_title：Journal of neurophysiology

authors： Kobayashi K,Winberry J,Liu CC,Treede RD,Lenz FA

更新日期：2009-05-01 00:00:00

abstract：:In recent years a small number of studies have applied functional imaging techniques to investigate visual responses in the human superior colliculus (SC), but few have investigated its oculomotor functions. Here, in two experiments, we examined activity associated with endogenous saccade preparation. We used 3-T fMRI...

journal_title：Journal of neurophysiology

authors： Furlan M,Smith AT,Walker R

更新日期：2015-08-01 00:00:00

abstract：:1. The spatial and temporal response characteristics of direction-selective neurons in the nucleus of the optic tract and dorsal terminal nucleus of the accessory optic system (NOT-DTN) of the wallaby were established using moving sinusoidal gratings. This is the first comprehensive investigation of the spatiotemporal...

journal_title：Journal of neurophysiology

authors： Ibbotson MR,Mark RF,Maddess TL

更新日期：1994-12-01 00:00:00

abstract：:1. To analyze further the sensory mechanisms for triggering the lordosis reflex, single-unit (n = 345) activity was recorded extracellularly from spinal segments L5-S1 of urethan-anesthetized female rats. Unit responses to pressure on the skin (necessary and sufficient for evoking lordosis) and other mechanical stimul...

journal_title：Journal of neurophysiology

authors： Kow LM,Zemlan FP,Pfaff DW

更新日期：1980-01-01 00:00:00

abstract：:Rats typically employ 4- to 12-Hz "whisking" movements of their vibrissae during tactile exploration. The intentional sampling of signals in this frequency range suggests that neural processing of tactile information may be differentially engaged in this bandwidth. We examined action potential responses in rat primary...

journal_title：Journal of neurophysiology

authors： Garabedian CE,Jones SR,Merzenich MM,Dale A,Moore CI

更新日期：2003-09-01 00:00:00

abstract：:It is well established that neural networks respond to a wide variety of modulatory substances by which they can become reconfigured, yet few studies have examined the effects of neurotransmitter mixtures on such networks. In a previous study of the medicinal leech using triple intracellular recordings, we found that ...

journal_title：Journal of neurophysiology

authors： Mesce KA,Crisp KM,Gilchrist LS

更新日期：2001-05-01 00:00:00

abstract：:We examined how subjects plan speeded reaching movements when the precise target of the movement is not known at movement onset. Before each reach, subjects were given only a probability distribution on possible target positions. Only after completing part of the movement did the actual target appear. In separate expe...

journal_title：Journal of neurophysiology

authors： Hudson TE,Maloney LT,Landy MS

更新日期：2007-11-01 00:00:00

abstract：:Dorsal root afferent depolarization and antidromic firing were studied in isolated spinal cords of neonatal rats. Spontaneous firing accompanied by occasional bursts could be recorded from most dorsal roots in the majority of the cords. The afferent bursts were enhanced after elevation of the extracellular potassium c...

journal_title：Journal of neurophysiology

authors： Kremer E,Lev-Tov A

更新日期：1998-05-01 00:00:00

abstract：:1. Firing of cerebral neuron, C-PR, produced complex bilateral movements of various regions of the body of the marine mollusc Aplysia californica. The movements were similar to those seen when the animal assumes the head-up feeding posture during food-induced arousal. Muscles of the neck largely contracted in transver...

journal_title：Journal of neurophysiology

authors： Nagahama T,Weiss KR,Kupfermann I

更新日期：1993-09-01 00:00:00

abstract：:The thalamic reticular nucleus (nRt) provides a major source of inhibition in the thalamo-cortical circuit and is critically involved in the generation of spindle oscillations. Here we describe the properties of thalamic giant depolarizing potentials (tGDPs) that were observed in nRt during early development. tGDPs pe...

journal_title：Journal of neurophysiology

authors： Pangratz-Fuehrer S,Rudolph U,Huguenard JR

更新日期：2007-03-01 00:00:00

abstract：:Dendritic voltage-dependent currents and inhibition modulate the information flow between synaptic and decision areas. Subthreshold and spike currents are sequentially recruited by synaptic potentials in the apical shaft of pyramidal cells, which may also decide cell output. We studied the global role of proximal apic...

journal_title：Journal of neurophysiology

authors： Canals S,López-Aguado L,Herreras O

更新日期：2005-02-01 00:00:00

abstract：:Visual search is a ubiquitous visual behavior, and efficient search is essential for survival. Different cognitive models have explained the speed and accuracy of search based either on the dynamics of attention or on similarity of item representations. Here, we examined the extent to which performance on a visual sea...

journal_title：Journal of neurophysiology

authors： Cohen MA,Alvarez GA,Nakayama K,Konkle T

更新日期：2017-01-01 00:00:00

abstract：:1. In alert macaque monkeys, multiunit activity is encountered in an alternating sequence of silent and spontaneously active zones as an electrode is lowered through the striate cortex (V1). 2. Individual neurons that are spontaneously active in the dark usually have a maintained discharge in the light. Because both t...

journal_title：Journal of neurophysiology

authors： Snodderly DM,Gur M

更新日期：1995-11-01 00:00:00

abstract：:Multichannel techniques were used to assess the frequency specificity of activation in the central nucleus of the inferior colliculus (CIC) produced by electrical stimulation of localized regions within the ventral cochlear nucleus (VCN). Data were recorded in response to pure tones from 141 and 193 multiunit clusters...

journal_title：Journal of neurophysiology

authors： Shivdasani MN,Mauger SJ,Rathbone GD,Paolini AG

更新日期：2008-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the most common neurological disorders causing memory reduction, particularly short-term memory (STM). We showed that, during TBI-induced inflammation, increased blood content of fibrinogen (Fg) enhanced vascular protein transcytosis and deposition of extravasated Fg in vasculo-a...

journal_title：Journal of neurophysiology

authors： Charkviani M,Muradashvili N,Sulimai N,Lominadze D

更新日期：2020-08-01 00:00:00

abstract：:A spherical approximation technique is presented that affords a mathematical characterization of a virtual space receptive field (VSRF) based on first-spike latency in the auditory cortex of cat. Parameterizing directional sensitivity in this fashion is much akin to the use of difference-of-Gaussian (DOG) functions fo...

journal_title：Journal of neurophysiology

authors： Jenison RL,Reale RA,Hind JE,Brugge JF

更新日期：1998-11-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00

abstract：:Single, teased fiber recordings were made from the decentralized right cervical vagus nerve (hyponodal) of the rat. A total of 67 afferent fibers that responded to gastric distension (GD) were studied: 9 fibers were stimulated by phasic balloon GD, 58 by more natural fluid GD. All balloon GD-responsive fibers had rest...

journal_title：Journal of neurophysiology

authors： Ozaki N,Sengupta JN,Gebhart GF

更新日期：1999-11-01 00:00:00

abstract：:Respiratory depression is a therapy-limiting side effect of opioid analgesics, yet our understanding of the brain circuits mediating this potentially lethal outcome remains incomplete. Here we studied the contribution of the rostral ventromedial medulla (RVM), a region long implicated in pain modulation and homeostati...

journal_title：Journal of neurophysiology

authors： Phillips RS,Cleary DR,Nalwalk JW,Arttamangkul S,Hough LB,Heinricher MM

更新日期：2012-11-01 00:00:00

abstract：:The neuromodulator acetylcholine (ACh) shapes neocortical function during sensory perception, motor control, arousal, attention, learning, and memory. Here we investigate the mechanisms by which ACh affects neocortical pyramidal neurons in adult mice. Stimulation of cholinergic axons activated muscarinic and nicotinic...

journal_title：Journal of neurophysiology

authors： Hedrick T,Waters J

更新日期：2015-04-01 00:00:00

abstract：:During an inspiration the output of hypoglossal (XII) motoneurons (HMs) in vitro is characterized by synchronous oscillatory firing in the 20- to 40-Hz range. To maintain synchronicity it is important that the cells fire with high reliability and precision. It is not known whether the intrinsic properties of HMs are t...

journal_title：Journal of neurophysiology

authors： van Brederode JF,Berger AJ

更新日期：2008-06-01 00:00:00