Abstract：
:The presence of interferon and type A immunoglobulins (IgA) was followed up in the nasopharyngeal washings collected from volunteers immunized intranasally with an inactivated influenza vaccine [strain A/Rom 1/73 (H3N2)]. Interferon was detected 24 hours after vaccine administration, its incidence being similar to that in the course of acute infection. Intranasal administration of inactivated influenza vaccine stimulated the production of secretory IgA in 3 of 10 samples collected 12 days after vaccination. At the same time, IgA were found in 4 samples collected before vaccination, and inhibited in certain cases the stimulation of interferon synthesis. The practical importance of the route of influenza vaccine administration is discussed.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Danielescu G,Barbu C,Sorodoc Y,Cajal N,Sărăteanu Dsubject
Has Abstractpub_date
1975-05-01 00:00:00pages
245-9issue
3eissn
0001-723Xissn
1336-2305journal_volume
19pub_type
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