Abstract：
:Reproduction of Hazara virus in intracerebrally (ic) inoculated newborn white mice was studied by virological, serological and histological methods, electron microscopy and the direct fluorescent antibody technique. In the course of infection the virus was detectable in the blood, brain and some viscera, the largest amounts of virus occurring in the brain and liver. Pathomorphological lesions were localized in the brain and consisted of foci of neuronal destruction and marked oedema of the tissue. Electron microscopy of ultrathin sections of tissues from various parts of brains of infected newborn white mice killed at the height of infection revealed virus particles in perikaryon of the brain cortex neurons; accumulations of particles were found in vesicles of the Golgi complex and the endoplasmic reticulum.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Smirnova SE,Shestopalova NM,Reingold VN,Zubri GL,Chumakov MPsubject
Has Abstractpub_date
1977-03-01 00:00:00pages
128-32issue
2eissn
0001-723Xissn
1336-2305journal_volume
21pub_type
杂志文章相关文献
ACTA VIROLOGICA文献大全abstract：:Interferon (IFN) was induced in chicken peripheral blood leukocytes by exposure to Concanavalin A (Con A). It has reached a maximum level 96 hr after stimulation with the optimum dose of 10 micrograms/ml. The IFN was partially purified by chromatography on controlled-pore glass adsorbent and was characterized as a fai...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:Transfer factor specific for herpes simplex virus (HSV) type 1 (TFHSV-1) was prepared from splenic cells of HSV-1 immunized mice. Protection was transferred with TFHSV-1 to nonimmune mouse recipients. The TFHSV-1 injected mice had a higher survival rate after lethal HSV-1 challenge as compared to mice injected with a ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:Palma and Bhanja bunyaviruses replicated in Dermacentor marginatus, D. reticulatus, Rhipicephalus sanguineus, R. appendiculatus and Ixodes ricinus ticks after parenteral inoculation and appropriate incubation and feeding. Palma virus was transmitted to D. marginatus and D. reticulatus males, D. reticulatus and R. sang...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:Sensitivity and specificity of a modified agar gel immuno-diffusion (AGID) test for the diagnosis of enzootic bovine leukosis was compared in 609 sera using the standard method, the modified test, and ELISA. The modifications concerned the composition of agar gel (1.8% Bacto-agar Difco), addition of polyethylene glyco...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：UNLABELLED:Antigenic and genetic typing of pestiviruses isolated from Indian sheep and goats was carried out. Testing of 1777 sheep and 1026 goat blood samples collected between 2004 and 2008 resulted in isolation of twelve pestiviruses, seven from sheep and five from goats. All of them were antigenically typed as bovi...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2012_03_209
更新日期：2012-01-01 00:00:00
abstract：:The effect of storage conditions on the serological activity of two strains of potato virus S (PVS), Andean and the ordinary, was studied by ELISA. Virus purificates, infected leaves and their homogenates, stored in lyophilized, frozen and dissolved form at various temperatures were tested. Virus purificates were most...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：:39K protein was proven to be the most notable hyperphosphorylated protein of Bombyx mori nucleopolyhedrovirus (BmNPV), since its amino acid 136 has the highest phosphorylation ratio (16.683) among all of BmNPV phosphorylated proteins (Shobahah et al., 2017). Therefore, we inserted positive (mimicking phosphorylation) ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2019_414
更新日期：2019-01-01 00:00:00
abstract：:2-0-hexadecyl-glycero-3-phosphocholine (GPC) 1 mmol/l solution reduced the infectivity of red clover mottle virus (RCMV) by over 90%. The binding of GPC molecules to RCMV particles was investigated with 1H-nmr spectroscopy, which showed a striking interaction between virus particles and GPC molecules. In 10 mmol/l GPC...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：:A lipophilic thermostable lipopolysaccharide (LPS) complex was isolated by phenol extraction from purified suspensions of the typhus group rickettsiae. The LPS complex is antigenic and possesses some endotoxic properties such as toxicity for actinomycin D-treated mice, pyrogenicity for rabbits and guinea pigs, ability...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:Peanut stripe virus (PStV) is one of the most common viruses infecting peanut that causes great economic losses every year. The 3ʹ-terminal 1082 bp of 74 PStV isolates collected from 12 districts of Shandong province, China were sequenced. Their coat protein (CP) genes were 864 bp in length and shared identities of 98...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2011_02_123
更新日期：2011-01-01 00:00:00
abstract：:Avian infectious bronchitis virus (IBV) and avian pathogenic Escherichia coli (APEC) are two important respiratory pathogens in the chicken. The co-infection can lead to chronic complications and considerable economic losses in the poultry industry worldwide. In the present study, we compared differential transcriptio...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2020_413
更新日期：2020-01-01 00:00:00
abstract：:The interferon system represents one of the components of the first line defence against influenza virus infection. Interferon omega (IFN-ω) is antigenetically different from IFN-α and IFN-β and can affect patients who are resistant to these IFNs. To improve the biological characterization of IFN-ω, we compared its ac...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2015_04_413
更新日期：2015-12-01 00:00:00
abstract：:Protective effects of different types of Q fever vaccines, namely untreated Coxiella burnetii phase I cells (Cb I) or Cb I cells treated with chloroform-methanol (CM) mixture (Cb I-CM) and of a Q fever chemovaccine obtained by trichloroacetic acid extraction (TCAE) from intact Cb I cells, were compared in mice and gui...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
abstract：:An assay protocol based on exploiting the polymerase chain reaction (PCR) for the direct detection of influenza B virus in throat swabs is described. By the use of PCR with nested primers, it was possible to detect the virus in throat swabs. Dilution experiments showed that as little as 1 plaque forming unit of virus ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:An abortive infection was induced in L cells by influenza virus A/Hong Kong/68 (H3N2). With the use of antibody and peroxidase-labelled protein A, the localization of virus protein synthesis but not the maturation of virus particles was demonstrated at the ultrastructural level. Five days after inoculation (p.i.), the...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：:The achievements and perspectives of genetic manipulations are described aiming at preparation of first generation subunit vaccines based on the synthesis in bacterial and eukaryotic cells of full-sized virion proteins expressing the main antigenic determinants. The preparation of such vaccines in bacterial cells seem...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：
更新日期：1985-05-01 00:00:00
abstract：:Chromosomal DNAs isolated from eight individuals from the Slovak population and from lymphoblastoid Namalwa cells were analyzed for the presence of genes coding for three subvariants of human interferon-alpha 2 (IFN-alpha 2), namely a, b, and c. The respective genes are regarded allelic, because they differ in the cod...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Acute isolates of Coxiella burnetii possess a 36-kbp plasmid termed QpH1. DNA hybridizations show that QpH1 contains approximately 6-kbp region of DNA which is not present in the QpRS plasmid from chronic isolates. This QpH1-specific region of DNA contains the contiguous EcoRI fragments G, E, and D. The GED region was...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:Herpes simplex virus (HSV) DNA was found by spot blot hybridization in the right nc. amygdalae of 3 out 10 patients who underwent curative stereotactic surgery for severe mental retardation with aggressive behavior and/or paranoic schizophrenia. Of these, 6 were also tested for the presence of CMV DNA sequences with n...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：:To monitor genetic variation between Cucumber mosaic virus (CMV) isolates of northwest Iran, samples of cucurbitaceous plants expressing symptoms similar to those caused by CMV were collected. The samples were first screened by ELISA to detect CMV and to determine its subgroup. All detected CMV isolates appeared to be...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Among diseases transmitted by ticks in the Czech Republic, tick-borne encephalitis (TBE) caused by Tick-borne encephalitis virus (TBEV) and Lyme disease caused by Borrelia burgdorferi spirochete are most important. We propose an effective and specific test for detection of TBEV in a single tick or a pool of ticks base...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Human respiratory syncytial virus (HRSV) is a leading pathogen causing lower respiratory tract infections in infants and young children worldwide. In line with the development of an effective vaccine against HRSV, a domain of the fusion (F) glycoprotein of HRSV was produced and its immunogenicity and antigenic propert...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2010_03_181
更新日期：2010-01-01 00:00:00
abstract：:In result of 20 pregnancies complicated by varicella 11 healthy and 6 defective offspring were born, 2 pregnancies were aborted by the physician and one pregnancy terminated by stillbirth of 3 siblings. Laboratory investigation of 16 pregnancies has shown that transplacental transfer of varicella-zoster (VZ) virus did...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：:Replication of vaccinia virus DNA in chick embryo fibroblasts at a high multiplicity of infection started after 4-6 hr, reached a maximum at the 12th hr and was completed 18 hr after inoculation (p.i.). An analysis of newly synthesised DNAs in the period of the highest rate of synthesis revealed the formation of short...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:In vivo phagocytosis activity of macrophages (PAM) was temporarily suppressed in mice by application of a suspension of microscopic from particles. As demonstrated, a reversible block of 70% of PAM was accompanied by a marked increase of the lethality during the acute tick-borne encephalitis (TBE) virus infection. Asy...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:The successive injection of non-immunomodulating doses of Tahyna virus (100 LD50) and non-immunomodulating doses of immunomodulating drugs, such as purified staphylococcal toxoid or glucosaminylmuramyldipeptide (Likopid), to mice were accompanied by a decrease in the IgM plaque-forming cell response to sheep red blood...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:Monoparacoumarylputrescinium chloride (pCPH), supplied to detached leaves of Gomphrena globosa via the petiole, induced interference with tomato bushy stunt virus infection by reducing the number and size of the necrotic local lesions. The phenolic compound neither inactivated directly the virus in vitro, nor induced ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：:A nation-wide vaccination against mumps that had been launched in the Czech Republic in 1987 eliminated great outbreaks (up to 100,000 cases per year) of this disease in 1955-1988, but did not prevent small outbreaks (a few thousand cases per year) in 1995-1996, 2005-2007, and 2010-2012. The extent of these small outb...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:A peculiar grouping of Creutzfeldt-Jacob disease (CJD) and of other organic presenile dementia (OPD) cases in a small, prevalently rural area in Czechoslovakia to the east of 19 degrees 35' E and to the north of 48 degrees 15' N was studied. Between August, 1972 and November, 1976, three histologically proven CJD case...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:An improved method of isolation of Coxiella burnetti proteins was developed. It consists of a combination of detergent (sodium dodecyl sulphate (SDS) or sodium deoxycholate (DOC) and hot phenol treatments. The resulting phenol phase (PP) contained either lipopolysaccharide-(LPS) free proteins (DOC extraction) or prote...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
