Prognostic potential of cytokines, nitrates, and APACHE II score in sepsis.

Abstract:

:The prognostic potentials of physiological ([Acute Physiologic and Chronic Health Evaluation] APACHE II score) and biochemical (Interleukin 6 [IL-6], Interleukin 6 soluble receptor [IL-6sR], and Interleukin 2 receptor [IL-2R], nitrates) measures were evaluated in sepsis. The APACHE II scores were calculated, and concentrations of the biochemical markers were measured, based upon information and samples obtained from 68 septic patients at time of diagnosis. Outcome (survival/non-survival) was determined at the end of the hospital stay associated with the septic episode. Statistically significant differences between survivors (S) and non-survivors (non-S) were found for APACHE II (p < 0.0001), IL-6 (p < 0.005), IL-6sR (p < 0.05), IL-2R (p < 0.02). No significant differences were found for nitrates. None of the markers could serve individually as an effective prognostic indicator. However, those markers demonstrating a significant difference between survivors and non-survivors may be able to contribute to a multi-parameter prognostic model.

journal_name

Ann Clin Lab Sci

authors

Bencosme A,Warner A,Healy D,Verme C

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

426-32

issue

5

eissn

0091-7370

issn

1550-8080

journal_volume

26

pub_type

杂志文章
  • Papillary glioneuronal tumor: a case report and review of the literature.

    abstract::We report a papillary glioneuronal tumor occurring in the right frontal lobe of a 26-yr-old woman and we review the pertinent literature. Papillary glioneuronal tumor (PGNT) is a rare cerebral neoplasm, identified in approximately 37 cases to date. In 2007, the World Health Organization (WHO) classified the PGNT as a ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Williams SR,Joos BW,Parker JC,Parker JR

    更新日期:2008-07-01 00:00:00

  • Cytologic diagnosis of multiple myeloma and macroglobulinemia in effusions.

    abstract::The presence of effusion in association with multiple myeloma or macroglobulinemia is an unusual finding which generally occurs late in the course of the disease. Occasionally, cytoligic detection is a diagnostic problem. In both conditions, the fluid is characrerized by a high specific gravity and high protein conten...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Gondos B,Miller TR,King EB

    更新日期:1978-01-01 00:00:00

  • Case report: acute spontaneous Achilles tendon rupture in a patient with giant cell arteritis.

    abstract::We report a case of a 69-yr-old previously healthy man with acute spontaneous Achilles tendon rupture and severe tendonitis, which occurred after 2 weeks of steroid therapy for newly diagnosed giant cell arteritis. The Achilles tendon rupture was treated conservatively and the tendonitis resolved incrementally with st...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Bunch TJ,Welsh GA,Miller DV,Santhi VS

    更新日期:2003-07-01 00:00:00

  • Comparison of the Abbott Architect i2000 assay, the Roche Modular Analytics E170 assay, and an immunoradiometric assay for serum hepatitis B virus markers.

    abstract::Serum hepatitis B virus (HBV) markers are the most important data for epidemiological screening and clinical diagnosis of HBV infection, especially in endemic areas. We compared the results of the Roche Modular Analytics E170 assay, the Abbott Architect i2000 assay, and an immunoradiometric assay (IRMA) for HBV surfac...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Kim H,Oh EJ,Kang MS,Kim SH,Park YJ

    更新日期:2007-07-01 00:00:00

  • Developments in laboratory diagnosis of chromosomal abnormalities.

    abstract::The development of chromosome banding techniques has made possible the detailed analysis of human chromosomes. A vast body of knowledge has accumulated during the last few years as a result of their application in biology and medicine. ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Frias JL

    更新日期:1975-09-01 00:00:00

  • Effect of increasing glucose concentrations on Sertoli cell viability in the nonobese diabetic mouse.

    abstract::Spermatogenesis is severely altered in the nonobese diabetic (NOD) mouse in the presence of diabetes. When insulin is administered early in the development of diabetic changes, blunting of the testicular damage results, suggesting a direct causal effect of hyperglycemia on the testicular alterations. In view of the ke...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Gondos B,Rivkind Y,Jovanovic L

    更新日期:1998-07-01 00:00:00

  • Tumors of striated muscle.

    abstract::Three benign forms of muscle tumors and three variants of rhabdomyosarcoma are discussed from the point of view of their histology and behabior. Recent combined modality therapy has significantly improved the prognosis in at least the embryonal form of rhabdomyosarcoma. ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Enterline HT

    更新日期:1975-11-01 00:00:00

  • A Pilot Study of RSK4 Expression in Patients with Human Non-Small Cell Lung Carcinoma.

    abstract:BACKGROUND:Lung cancer represents the leading cause of cancer deaths worldwide, with non-small cell lung carcinoma (NSCLC) comprising the most common type of lung cancer. OBJECTIVE:The aim of this pilot study was to ascertain RSK4 expression at both the gene and protein level in normal and cancerous tissue of patients...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Li A,Liu D,Liu Y,Zhou Y,Du Z,Song J

    更新日期:2018-07-01 00:00:00

  • Overnight storage of blood in ACD tubes at 4{degrees}C increases NK cell fraction in peripheral blood mononuclear cells.

    abstract::A considerable variabilility in the effects of sample handling on NK cytotoxicity has been observed. Using flow cytometry, NK cytotoxicity assays and lymphocyte subset analysis of Ficoll-Hypaque-separated peripheral blood mononuclear cells (PBMCs) isolated from whole blood stored under various conditions were performe...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Kim DW,Jang YY,Shin MG,Shin JH,Suh SP,Ryang DW,Yoon M,Lee JJ,Kim SK,Cho D

    更新日期:2013-07-01 00:00:00

  • Streptococcus milleri group (Streptococcus anginosus): recovery from intra-abdominal and soft tissue sites.

    abstract::One hundred thirty-three Streptococcus milleri group (S. anginosus) isolates were recovered from 487 surgical patients. The streptococci were recovered from 33 percent of intra-abdominal infection cultures (84/257). 22 percent of samples from penetrating visceral trauma (19/86), 52 percent of perirectal abscess specim...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Edmiston CE Jr,Walker AP,Krepel CJ,Gohr CM,Seabrook GR,Frantzides CT

    更新日期:1991-01-01 00:00:00

  • Comparison of Abbott RealTime High-Risk HPV and Hybrid Capture 2 Assays for Detection of HPV Infection.

    abstract:BACKGROUND:Various assays for detecting high-risk human papillomavirus (HR HPV) have been introduced recently, including the Abbott RealTime High-Risk HPV assay. We sought to compare the performance of Abbott PCR to Hybrid Capture 2 for the detection of HR HPV. METHODS:A total of 941 cervical swab specimens were obtai...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Ko K,Yu S,Lee EH,Park H,Woo HY,Kwon MJ

    更新日期:2016-09-01 00:00:00

  • Matrine Suppresses Proliferation and Invasion of SGC7901 Cells through Inactivation of PI3K/Akt/uPA Pathway.

    abstract::This study was to examine the inhibitory effect of matrine on the proliferation and metastasis of gastric cancer cells, and to explore the possible mechanisms involved in these processes. MTT was used to evaluate the proliferation ability of SGC7901 cells. A two and three-dimensional cell migration assay were performe...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Peng X,Zhou D,Wang X,Hu Z,Yan Y,Huang J

    更新日期:2016-09-01 00:00:00

  • Determination of plasminogen in human serum or plasma by a fibrometric method.

    abstract::A simple, fast, reproducible, and reliable fibrometer method for determination of plasma or serum plasminogen was developed. Results obtained with this method were compared to those obtained with a Coseinolytic method and a Chromogenic Substrate S-2251 method. For all three procedures, serum or plasma samples were aci...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Sarji NM,Liu PI,Teaford MJ,Crook L

    更新日期:1981-09-01 00:00:00

  • Finger-loops, oncogenes, and metals. Claude Passmore Brown memorial lecture.

    abstract::Certain DNA-binding proteins that regulate gene expression contain single or multiple copies of short polypeptide sequences, approximately 30 residues long, consisting of combinations of four Cys or His residues at defined spacing, so that Zn++ is complexed in tetrahedral coordination with the respective thiol-sulfur ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Sunderman FW Jr,Barber AM

    更新日期:1988-07-01 00:00:00

  • Pathogenic analysis of Aeromonas hydrophila septicemia.

    abstract::Aeromonas hydrophila has emerged as a potential pathogen in the immunocompromised host. Various aeromonal infections, including septicemia, have also been reported in apparently healthy individuals. For years, researchers have disagreed over the epidemiologic roles of aeromonads in gastroenteritis. Isolation rates of ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Chang CY,Thompson H,Rodman N,Bylander J,Thomas J

    更新日期:1997-07-01 00:00:00

  • Some aspects of bilirubin determination in the newborn using dimethyl sulfoxide.

    abstract::Although serum bilirubin determination is a common procedure in most clinical laboratories, the test seems to be of particular importance in the screening of neonates, especially the premature or the erythroblastotic infant. However, bilirubin determination is subject to interferences, particularly in the presence of ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Baginski ES,Epstein E,Zak B

    更新日期:1980-11-01 00:00:00

  • Evaluation of a bioassay method for serum amikacin concentrations.

    abstract::The bioassay system from American Diagnostic for amikacin was compared to the same company's radioimmunoassay (RIA) technique used in this hospital. The bioassay is performed by adding serum from a patient to wells cut in agar which have been seeded with a susceptible fast growing microorganism (Enterobacter). After i...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Manos JP,Botting AJ,Burdash NM,Mason MH,West ME

    更新日期:1981-09-01 00:00:00

  • Acute myelofibrosis--a leukemia of pluripotent stem cell. A report of three cases and review of the literature.

    abstract::The histogenesis of blasts in acute myelofibrosis is generally regarded to be of megakaryocytic origin. Three case reports are presented and 19 other reported cases were reviewed from the literature where the cells of origin appear to be myeloblasts, myelomonoblasts, lymphoblasts, or undifferentiated blasts. It is the...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Amberger DM,Saleem A,Kemp BL,Truong LD

    更新日期:1990-11-01 00:00:00

  • Histochemistry of steroid receptors in prostatic diseases.

    abstract::Tissue obtained from 55 men with prostatic disease was assayed for estrogen and androgen receptors by a newly developed histochemical technique. The material studied consisted of 45 specimens of benign nodular prostatic hyperplasia and 10 specimens of prostatic adenocarcinoma. The results obtained were compared to tho...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Pertschuk LP,Zava DT,Gaetjens E,Macchia RJ,Wise GJ,Kim DS,Brigati DJ

    更新日期:1979-05-01 00:00:00

  • Pathology and immunology of Clonorchis sinensis infection of the liver.

    abstract::The existence of clonorchiasis cases among the Asian immigrants and the major clinical and pathologic features encountered in those patients is emphasized. Owing to the longevity of the parasite, clinical symptoms may occur long after endemic exposure. The common manifestations among the immigrants are recurrent pyoge...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Sun T

    更新日期:1984-05-01 00:00:00

  • Homogeneous enzyme immunoassay for theophylline with a centrifugal analyzer.

    abstract::A rapid homogeneous enzyme immunoassay for theophylline has been adapted to a centrifugal analyzer. The sample volume used was 10 microliter and sera from as many as 28 patients could be measured in 180 seconds. The assay temperature was 30 degrees and the absorbance rates were measured at 340 nm. Within-run and run-t...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Lacher DA,Sinn JA,Savory J,Wills MR

    更新日期:1980-07-01 00:00:00

  • Comparison of Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry (MALDI-TOF MS) and the Vitek 2 System for Routine Identification of Clinically Relevant Bacteria and Yeast.

    abstract:OBJECTIVE:In this study, we compared the observed agreement and correlation of the Vitek 2 system with the biomarker-based MALDI-TOF MS identification results of bacteria and yeast on a routine basis. METHODS:Clinical isolates collected from two years were included. Isolates were identified using the Vitek 2 system an...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Garza-González E,Camacho-Ortíz A,Rodríguez-Noriega E,Esparza-Ahumada S,Flores-Treviño S,Bocanegra-Ibarias P,Tijerina-Rodríguez L,Morfín-Otero R

    更新日期:2020-01-01 00:00:00

  • Recent advances in calcium and phosphorus metabolism.

    abstract::This review considers the most recent developments concerning the metabolism and homeostasis of calcium and phosphorus. The kinetics of the distribution of calcium, theories of calculus formation, hypercalcemia and hypocalcemia are discussed, as well as the role of parathyroid hormone, thyrocalcitonin and 1,25 dihydro...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Schwartz MK

    更新日期:1975-05-01 00:00:00

  • The incidence and significance of pseudoparaproteins in a community hospital.

    abstract::Pseudoparaproteins were observed in 129 (10.5%) of 1,229 high resolution protein electrophoretic fractionations of serum (N = 847), urine (N = 368), or cerebrospinal fluid (N = 14) performed in this laboratory during a 12-month period. The pseudoparaproteins identified in serum electrophoretic patterns included fibrin...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Strobel SL

    更新日期:2000-07-01 00:00:00

  • Automated spectrophotometric assay for urine p-aminophenol by an oxidative coupling reaction.

    abstract::Urine p-aminophenol (PAP) concentration serves as a biological marker for occupational exposures to aniline. We report the development of a rapid, simple spectrophotometric method for quantification of urine PAP concentration using a chemical autoanalyzer (Olympus Reply). The method involves oxidative coupling of PAP ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Chen CF,Tseng YT,Tseng HK,Liu TZ

    更新日期:2004-07-01 00:00:00

  • Effect of insulin on testicular alterations in the nonobese diabetic mouse.

    abstract::Severe spermatogenic alterations occur in association with diabetic manifestations in the nonobese diabetic (NOD) mouse. A study was undertaken to determine whether or not administration of insulin during initial appearance of diabetic changes could inhibit the interference with spermatogenesis. Male NOD mice injected...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Gondos B,Bevier W

    更新日期:1995-05-01 00:00:00

  • Sensitivity of serum fructosamine in short term glycemic control.

    abstract::The serum fructosamine concentrations measured in 64 diabetic patients correlated (r = 0.73) with glycated hemoglobins (HbA1c). However, 23 percent of the diabetic patients had normal fructosamine and abnormal HbA1c levels. In order to determine whether or not the discrepant values were the result of recent glycemic r...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Prior TW,Chapman JF,Bankson DD

    更新日期:1989-03-01 00:00:00

  • Simple, direct determination of serum 5'-nucleotidase.

    abstract::A simple determination of 5'-Nucleotidase in blood serum without deproteinization is described. The enzyme activity is distinguished from that of a nonspecific alkaline phosphatase by nickel inhibition and the inorganic phosphate released from adenosine monophosphate used as substrate is determined by a method previou...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Baginski ES,Marie SS,Epstein E,Zak B

    更新日期:1977-11-01 00:00:00

  • T-cell prolymphocytic leukemia with a suppressor phenotype.

    abstract::A diagnosis of prolymphocytic leukemia was made from the blood and bone marrow of a 50 year old man. The neoplastic cells were studied by use of light and electron microscopy. Neoplastic cells were focally positive for acid phosphatase and alpha naphthyl acetate esterase. In addition, neoplastic cells formed rosettes ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Planas AT,Zamkoff KW,Poiesz BJ,Kurec AS,Davey FR

    更新日期:1983-05-01 00:00:00

  • Inhibitors of 11 beta-hydroxysteroid dehydrogenase and 5 beta-steroid reductase in urine from patients with congestive heart failure.

    abstract::Recently, the current authors reported the presence in normotensive male and female urines of reproducibly measurable levels of naturally occurring substances in partially purified extracts of urine with inhibitory activity like glycyrrhetic acid (GA) towards both 11 beta-hydroxysteroid dehydrogenase (11 beta-OHSD) an...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Semafuko WE,Sheff MF,Grimes CA,Latif SA,Sadaniantz A,Levinson P,Morris DJ

    更新日期:1993-11-01 00:00:00