Abstract:
:This study investigates the histories and the clinical course of 111 patients who had nonlesional temporal lobe epilepsy. We compared 61 patients with unilateral hippocampal sclerosis (UHS group) and 50 patients with minimal change (MRI negative group) assessed on the basis of MRI. In agreement with previous reports, we confirmed statistically that patients in the UHS group strongly tended to have had febrile convulsive status during early childhood or infancy and that habitual seizures tended to begin at a younger age than the other subset of nonlesional temporal lobe epilepsy. Strikingly, episodes of psychoses, especially postictal psychoses, occurred significantly more often in the UHS group than in the MRI negative group. Additional involvement of temporal neocortex further augmented this association. We stress the role of mesial temporal pathology, and its linkage to the temporal neocortex, in the genesis of postictal psychoses.
journal_name
Neurologyjournal_title
Neurologyauthors
Kanemoto K,Takeuchi J,Kawasaki J,Kawai Idoi
10.1212/wnl.47.5.1199subject
Has Abstractpub_date
1996-11-01 00:00:00pages
1199-203issue
5eissn
0028-3878issn
1526-632Xjournal_volume
47pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:BACKGROUND/OBJECTIVE:Apoptosis, or programmed cell death, is an evolutionary conserved mechanism essential for morphogenesis and tissue homeostasis, but it plays an important role also in pathologic conditions, including neurologic disorders. Its execution pathway is critically regulated at the mitochondrial level. Evi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.8.1070
更新日期:2001-04-24 00:00:00
abstract::Photoparoxysmal response (PPR) is sometimes incidentally encountered in EEGs performed for evaluation of nonepileptic symptoms. We conducted the first long-term study of a cohort of nonepileptic patients to determine their risk of having seizures subsequent to incidental recording of PPR. After 6 to 12 years (mean, 9 ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.9.1719
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVE:To estimate whole-brain microinfarct burden from microinfarct counts in routine postmortem examination. METHODS:We developed a simple mathematical method to estimate the total number of cerebral microinfarcts from counts obtained in the small amount of tissue routinely examined in brain autopsies. We derived...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31828c2f52
更新日期:2013-04-09 00:00:00
abstract:OBJECTIVE:To define the clinical and radiologic features of brainstem gliomas (BSGs) in children with neurofibromatosis type 1 (NF1). METHODS:We performed a retrospective cross-sectional study of 133 children with NF1 and concurrent BSGs cared for at 4 NF1 referral centers. BSG was determined using radiographic criter...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000003881
更新日期:2017-04-18 00:00:00
abstract::A seismic shift in our understanding of the ability to diagnose Alzheimer disease (AD) is occurring. For the last several decades, AD has been a clinical-pathologic diagnosis, and this conceptualization of the disease has served the field well. Typically, the clinician would identify a syndrome such as mild cognitive ...
journal_title:Neurology
pub_type: 历史文章,杂志文章
doi:10.1212/WNL.0000000000006088
更新日期:2018-08-28 00:00:00
abstract::Orthostatic hypotension is a fall in blood pressure on standing that causes symptoms of dizziness, visual changes, and discomfort in the head and neck. The goal of treatment is the improvement of the patient's functional capacity, rather than a target blood pressure. For treatment to be successful, it must be individu...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To assess the effect of usage of three different versions of Creutzfeldt-Jakob disease (CJD) diagnostic criteria on estimates of CJD incidence. METHODS:A total of 428 patients referred for suspected sporadic CJD between 1991 and 1997 were classified according to different criteria to be compared after analys...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.54.5.1095
更新日期:2000-03-14 00:00:00
abstract:OBJECTIVE:To use punch skin biopsies to evaluate the loss of intra-epidermal nerve fibers in sensory neuropathies. BACKGROUND:Previous assessments of epidermal nerve fibers have been constrained by relatively insensitive staining techniques and variability in quantification. METHODS:Punch skin biopsies were performed...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.10.1848
更新日期:1995-10-01 00:00:00
abstract::Factors affecting osmotic fragility were studied in red blood cells of patients with Duchenne muscular dystrophy. The mean osmotic fragility (MOF), operationally defined as the NaCl concentration for 50% hemolysis, was found to be higher by 3.63 +/- 0.51 mM in Duchenne cells than in normal cells having an MOF of 60.1 ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.30.7.726
更新日期:1980-07-01 00:00:00
abstract:OBJECTIVE:To report the development of CNS vasculitis in a patient with multiple sclerosis (MS) treated with daclizumab. METHODS:This report includes clinical, MRI, immunologic, and pathology data and CSF analysis. RESULTS:After completing a phase II daclizumab monotherapy study with an optimal response as evidenced ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31827f0f42
更新日期:2013-01-29 00:00:00
abstract:BACKGROUND:Frontotemporal dementia (FTD) is currently distinguished from AD primarily on the basis of behavioral features because studies of cognition have shown negligible or inconsistent differences. However, the poor discriminability of cognitive measures may relate to reliance on imprecise clinically diagnosed grou...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.58.12.1801
更新日期:2002-06-25 00:00:00
abstract:OBJECTIVE:To investigate whether cognitive function is related to incidence of stroke. METHODS:A population-based cohort of 1551 subjects with no clinical history or signs of stroke, age 75 years and over at baseline, were followed up for 3 years. Individuals with a first-ever stroke event that was recorded in the Sto...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.54.11.2103
更新日期:2000-06-13 00:00:00
abstract:OBJECTIVE:To describe the characteristics of late-onset multiple sclerosis (MS) (LOMS, 50+ years) vs adult-onset MS (AOMS, 16 to <50 years) and examine prognosis and associated risk factors. METHODS:Patients with definite MS, onset prior to July 1988, registered with a BCMS clinic before July 1998, with at least one E...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000237475.01655.9d
更新日期:2006-09-26 00:00:00
abstract:OBJECTIVES:Compensatory processes involving the recruitment of additional cerebral areas can limit cognitive impairment caused by brain damage as revealed by fMRI. Multiple sclerosis (MS) is characterized by frequent cognitive deficiencies and diffuse brain damage. Understanding the missing or disturbed processes resul...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181f612e3
更新日期:2010-10-05 00:00:00
abstract::In the current medical climate, medical education is at risk of being de-emphasized, leading to less financial support and compensation for faculty. A rise in compensation plans that reward clinical or research productivity fails to incentivize and threatens to erode the educational missions of our academic institutio...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000007664
更新日期:2019-07-02 00:00:00
abstract:OBJECTIVE:To analyze the relationship between retinal thinning and nigral dopaminergic loss in de novo Parkinson disease (PD). METHODS:Forty-nine patients with PD and 54 age-matched controls were analyzed. Ophthalmologic examination and macula optical coherence tomography scans were performed with additional microperi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006157
更新日期:2018-09-11 00:00:00
abstract::The incidence of MS in the Orkney Islands has been updated from 1941 to September 21, 1983. Since 1965, MS incidence rates have fallen significantly when compared with those for 1941 to 1964. Alterations in age-specific prevalence, mean duration of illness, and mean age of the MS population are consistent with the dec...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.4.545
更新日期:1985-04-01 00:00:00
abstract:OBJECTIVE:To report a case of Lambert-Eaton myasthenic syndrome (LEMS) in a child and review the existing literature of LEMS in children. METHODS:We report a pediatric case of LEMS with the classic clinical triad of proximal weakness, autonomic dysfunction, and areflexia; the characteristic increment in compound motor...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0b013e318293e14e
更新日期:2013-05-21 00:00:00
abstract:OBJECTIVES:The objective of this study was to clarify the characteristic brain MRI findings for genetically diagnosed CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy). METHODS:Seven patients with CARASIL carrying HTRA1 mutations (representing 6 Japanese families) we...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001803
更新日期:2015-08-04 00:00:00
abstract:OBJECTIVE:This study investigated the sex difference in prevalence of depression at 90 days after first-ever stroke. METHODS:Patients with first-ever stroke (n = 786) were identified from the population-based Brain Attack Surveillance in Corpus Christi project (2011-2016). Poststroke depressive symptoms were assessed ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000009394
更新日期:2020-05-12 00:00:00
abstract:OBJECTIVE:Because age affects hormonal production differently in women compared with men, we sought to define sex and age interactions across a multiracial/ethnic population after intracerebral hemorrhage (ICH) to uncover evidence that loss of gonadal hormone production would result in loss of the known neuroprotective...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000004255
更新日期:2017-09-05 00:00:00
abstract:OBJECTIVE:To use a historical placebo control design to determine whether lithium carbonate slows progression of amyotrophic lateral sclerosis (ALS). METHODS:A phase II trial was conducted at 10 sites in the Western ALS Study Group using similar dosages (300-450 mg/day), target blood levels (0.3-0.8 mEq/L), outcome me...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0b013e31822dc7a5
更新日期:2011-09-06 00:00:00
abstract::Cost-effective approaches for arriving at correct diagnoses should be used. Herein, we compare three approaches for the differential diagnosis of a common neurologic syndrome, peripheral neuropathy. In the "shotgun" approach, a standard battery of hematologic, biochemical, serologic, antibody, enzyme, molecular geneti...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.47.1.10
更新日期:1996-07-01 00:00:00
abstract::We prospectively evaluated 84 consecutive adult patients with chronic liver disease before and after liver transplantation to define the type and frequency of post-transplant neurologic complications, and to assess possible pretransplant and operative variables associated with in-hospital CNS complications. There were...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.7.1226
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:Frontotemporal dementia associated with motor neuron disease (FTD-MND) is a rare neurodegenerative disorder that may be inherited by autosomal dominant trait. No major gene has been identified but a locus was mapped on chromosome 9 (9p21.3-p13.3). METHODS:Ten French families with FTD-MND were tested for lin...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181a55f1c
更新日期:2009-05-12 00:00:00
abstract::A 60-year-old man presented with progressive large fiber sensory loss in the right first three fingers and, to a lesser extent, in both fourth and fifth fingers. Electrophysiologic studies were characteristic of chronic sensory demyelinating polyneuropathy, a variant of chronic inflammatory demyelinating polyneuropath...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.1.253
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To review the disciplinary process by which the American Academy of Neurology (AAN) enforces its formalized standards of professional conduct. METHODS:We reviewed the AAN's Disciplinary Action Policy. We tracked the elapsed time from receipt to final decision of all allegations ("complaints") of improper con...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318202014e
更新日期:2010-12-14 00:00:00
abstract::We tested serum specimens from patients with HAM/TSP and asymptomatic HTLV-I carriers from endemic areas of Japan, Jamaica, Colombia, and Chile for neutralizing antibodies against HTLV-I. The data suggest a trend for neutralizing activity to be found more frequently in the sera from HAM/TSP patients than in sera from ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.11.2210
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:The state-of-the-art tools of neurology, in particular modern neuroimaging techniques, have yet to benefit from the revolution in mobile technologies that provide new insights into the mechanisms underlying clinical syndromes. This study demonstrates the manner in which mobile technologies may provide informa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31824528b2
更新日期:2012-01-31 00:00:00
abstract::We performed serial baseline and gadolinium (Gd)-DTPA-enhanced MRI in 4 patients with definite multiple sclerosis. Studies were performed every month for a total of 4 scans. We obtained short TR/short TE sequences at 10 and 60 minutes after Gd-DTPA injection. All patients had multiple hyperintense lesions seen on base...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.40.4.591
更新日期:1990-04-01 00:00:00