Abstract：
BACKGROUND:While many studies have focused on life events in depressive disorders, data regarding them in bipolar disorder are scant. The aim of this work was to explore the characteristics of life events in bipolar patients. METHODS:Sixty bipolar patients have been included in our study. The evaluation focused on the sociodemographic and clinical characteristics with a standardized measurement of life events using Paykel's interview. The results were compared with those of siblings and healthy controls groups. The three groups were matched for age and sex. RESULTS:Compared to the controls, bipolar patients and their siblings had a higher global score of life events and more events in the fields of work, socio-family events and health. Bipolar patients reported more desirable events compared with their siblings and controls. The siblings reported higher scores of uncontrollable and undesirable events than patients and controls, and a higher score of controllable events than patients. LIMITATIONS:The Paykel's interview has no validated Tunisian version, which could be a methodological bias in the assessment of life events. Moreover, the assessment of the life events was made during the euthymic phase of the bipolar disorder; however, there was no standardized measure of mood symptoms, to confirm this euthymia. CONCLUSION:Our findings could help in the identification of the etiopathogeny of bipolar disorder and would contribute to improve the understanding and management of these patients focusing on the psychosocial aspect which is often overlooked.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
El Kissi Y,Krir MW,Ben Nasr S,Hamadou R,El Hedda R,Bannour S,Ben Hadj Ali Bdoi
10.1016/j.jad.2013.05.098subject
Has Abstractpub_date
2013-10-01 00:00:00pages
378-83issue
1eissn
0165-0327issn
1573-2517pii
S0165-0327(13)00482-5journal_volume
151pub_type
杂志文章abstract：OBJECTIVE:The purpose of this study was to evaluate the effects of prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) on obstetrical and neonatal outcomes. METHOD:A case-control study was conducted to compare perinatal outcomes among pregnant women with affective disorder (DSM-IV criteria) and who re...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2011.07.022
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Emotional sensitivity involves the ability to recognize and interpret facial expressions. This is very important for interpersonal communication. Previous studies found differences in emotional sensitivity between high social anxiety (HSA) individuals and low social anxiety (LSA) individuals. However, the un...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.09.111
更新日期：2021-01-15 00:00:00
abstract：BACKGROUND:Various associations between monthly Google search volumes (MGSVs) and monthly suicide rates (MSRs) have been reported. However, these studies often analyzed a limited number of search terms using suboptimal statistical methods. While controlling for spurious associations, this study examined a wide array of...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.11.014
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:It has been established that depressed patients manifest a higher risk of committing suicide. The role of delusional experiences accompanying depressive symptomatology as a risk factor for suicidal behaviour has been investigated but the results are inconsistent. METHOD:In the present study, 40 elderly depr...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(00)00322-0
更新日期：2002-05-01 00:00:00
abstract：BACKGROUND:Several studies have demonstrated that adjuvant therapies as exercise and breathing training are effective in improving cardiac autonomic control (CAC) in patients with affective spectrum disorders. However, the effects of Sudarshan Kriya Yoga (SKY) on autonomic function in this population is unknown. Our ob...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.03.017
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVES:Mixed episodes are a combination of depressive and manic symptoms in bipolar disorder (BD). We want to identify the proportion of patients who have depressive symptoms during an acute episode and also the validity of current methods for its diagnosis. MATERIAL AND METHOD:Cross-sectional multicentre study of...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.12.019
更新日期：2010-09-01 00:00:00
abstract：:The relationship between ventricular brain ratio (VBR) and clinical variables was investigated in 21 DSM-III depressed patients. None of the following dichotomies--major depression vs. dysthymic disorder, suicidal vs. non-suicidal patients, male vs. female patients--showed any statistically significant differences. An...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(87)90035-8
更新日期：1987-05-01 00:00:00
abstract：BACKGROUND:Given the prevalence of anxiety, depression, and stress among university students, it is important to assess the effectiveness of prevention programs for these problems. Beyond examining effect sizes, applying a common elements approach can enhance our understanding of which practice elements are most freque...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.06.035
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Social network, loneliness, generalized anxiety disorder (GAD) and major depression disorder (MDD) are interrelated. However, as the directions of these associations are still unclear, we examined them prospectively using community-based data. METHODS:Data on 5066 adults aged ≥50 years from The Irish Longit...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2018.12.043
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Patients who deliberately harm themselves often repeat their self-destructive acts. The objective of this study was to assess whether a follow-up visit within 10 days to a psychiatric consultant could reduce the frequency of repeated deliberate self-harm (DSH). METHODS:A cohort of 325 consecutive DSH patien...
journal_title：Journal of affective disorders
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jad.2013.09.032
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Cross sectional research suggests that negative religious coping (e.g., anger at God and religious disengagement) strongly correlates with depression and anxiety. However, causality is difficult to establish as negative coping can accompany, cause, or result from distress. Among Orthodox Jews, some studies h...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2011.03.015
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:Electroconvulsive therapy (ECT) is an effective mode of treatment--especially for severe depression and for depression refractory to pharmacotherapy, nevertheless the mode of action of ECT is far from being fully understood. This study assessed the effects of a series of ECT in depressive subjects on cerebral...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.07.034
更新日期：2013-04-05 00:00:00
abstract：BACKGROUND:We tested if duration and intensity of episodes in treatment-resistant affectively ill patients were related to cerebrospinal fluid (CSF) concentrations of monoamine metabolites. METHOD:In retrospective life charts were recorded every previous episode of 37 patients with severe treatment-refractory affectiv...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/s0165-0327(02)00011-3
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Depression is associated with an increased risk of cardiovascular diseases (CVD) and cardiovascular mortality. We investigated to what extent subjective health status explained the apparent association between depressive symptoms and cardiovascular mortality in older European men. METHODS:Data were used fro...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2008.07.005
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Comorbid ADHD symptoms may partly account for circadian rhythm disturbances in depression and anxiety disorders. METHODS:Self-reported sleep characteristics of 2090 participants in the Netherlands Study of Depression and Anxiety were assessed using the Munich Chronotype Questionnaire. We defined 3 groups: h...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.04.022
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Little is known about medical comorbidity or health-related quality of life (HRQOL) in bipolar disorder across the adult age span, especially in public sector patients. METHODS:We obtained cross-sectional demographic, clinical, and functional ratings for 330 veterans hospitalized for bipolar disorder with M...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2004.12.006
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-adrenal (HPA) axis and depression but a causal relationship has not been established. This study aimed to evaluate the effects of vitamin D supplementation on depression severity, serum 25(OH)D, and some neurotransmitters in patie...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.03.029
更新日期：2020-05-15 00:00:00
abstract：:Eighty-six patients suffering from nonpsychotic unipolar major depressive disorder, according to Research Diagnostic Criteria, were rated on a modified Hamilton Rating Scale for Depression (HRS). All completed the self-rating Beck Depression Inventory (BDI). Distal colon motility (dcm) studies, performed in all the pa...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(83)90032-0
更新日期：1983-02-01 00:00:00
abstract：AIMS:Earlier studies show that participation in mind and body exercises (MBE) is cross-sectionally associated with high levels of depressive symptoms and antidepressants. This study investigates the longitudinal interrelationship between depressive symptoms, MBE and antidepressants. METHODS:3269 men and 4318 women age...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2020.01.012
更新日期：2020-03-15 00:00:00
abstract：BACKGROUND:Some evidence suggests that individuals with bipolar spectrum disorders (BSD) generate stressful life events, contributing to a more severe course of disorder. A recent update to the Behavioral Approach System (BAS) dysregulation theory of BSD highlights the need to investigate anger as approach motivation. ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2012.07.022
更新日期：2013-04-05 00:00:00
abstract：BACKGROUND:Anxiety is extremely common in dementia and can lead to social exclusion, excess disability and associated problems including high physical dependency, problems in the patient/carer relationship, and increased cognitive and behavioural difficulties. Despite this, there is little research on the detection or ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2009.12.015
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Depression often co-occurs in late-life in the context of declining cognitive functions, but it is not clear whether specific depression symptom dimensions are differentially associated with cognitive abilities. METHODS:The study sample comprised 3107 community-dwelling older adults from the Longitudinal Ag...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.05.027
更新日期：2016-09-01 00:00:00
abstract：:Direction of weight change in depression has recently been reported to be mediated by Body Mass Index (BMI). The present study examined the relation between direction of weight change in unipolar depression, BMI, and clinical variables such as severity of depression, melancholia, chronicity and recurrence in 89 patien...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/0165-0327(94)90151-1
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:Brain-derived neurotrophic factor (BDNF) has been hypothesized to be involved in the neurobiology of major depression. The aim of this study was to assess the possible relationships between depressive symptoms and serum and/or plasma BDNF levels during 1 year of antidepressant treatment. METHODS:Plasma and ...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2007.05.005
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Chronic depression is a particularly disabling mood disorder and treatment outcomes are poor with either psychotherapy or pharmacotherapy alone. There is growing evidence that an integrative treatment approach may be optimal. A novel multi-modal, multi-disciplinary treatment program, Re-ChORD, was developed ...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2009.10.015
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:Depressive recurrence is highly prevalent and adds significantly to the burden of depressive disorder. Whilst some clinical predictors of recurrence have been clearly demonstrated (e.g. residual symptoms, previous episodes), the cognitive and psychological processes that may contribute to recurrence risk are...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2019.05.072
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:Somatic symptoms have been suggested to negatively affect the course of major depressive disorder (MDD). Mechanisms behind this association, however, remain elusive. This study examines the impact of somatic symptoms on MDD prognosis and aims to determine whether this effect can be explained by psychiatric ch...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2016.06.030
更新日期：2016-11-15 00:00:00
abstract：BACKGROUND:Patients with bipolar disorder (BD) present widespread and significant neurocognitive impairments during all stages of the disorder. Repetitive transcranial magnetic stimulation (rTMS) has been used to improve clinical outcomes in common psychiatric diseases, such as depression, anxiety disorders, schizophre...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2018.12.102
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:In a population of patients with manic and mixed mood episodes, olanzapine has proven effective in maintaining response, as compared to placebo. Whether this is true for the subpopulation of patients with a mixed index episode is not known. METHODS:Post-hoc analyses were conducted on data from patients pres...
journal_title：Journal of affective disorders
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jad.2008.11.003
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:More than 50% of individuals with bipolar disorder (BD) do not reach full psychosocial functioning, even during periods of euthymia. It has been suggested that history of psychotic symptoms is one of the factors which are associated with a worse functional outcome. The objective was to compare psychosocial f...
journal_title：Journal of affective disorders
pub_type： 杂志文章
doi：10.1016/j.jad.2017.12.094
更新日期：2018-03-15 00:00:00
