Elderly and very elderly patients with hepatocellular carcinoma. Strategy for a first line treatment.

Abstract:

AIM:Health-status of elderly patients with hepatocellular carcinoma (HCC) may limit surgical approach; other options are thus auspicable. METHODS:The authors reviewed 98 selected patients, aged 65 to 90 years, with 149 HCC treated between 2002 and 2011. According to the extent of malignancy, health status and treatment, patients were divided into 3 groups. Sixty-one, submitted to major and minor curative resections, were in group A and B while group C included 37 patients, unsuitable for high-risk procedures and percutaneous ablation, submitted to intraoperative-radiofrequency ablation (IRFA) alone or combined with minor resections. Assessment of safety and therapeutic efficacy of this managment was evaluated. RESULTS:A postoperative mortality rate of 1,02% and an overall survival rate at 5 years of 62.3% were observed. Indeeed matched post-operative morbidity and mortality rates of A, B, C groups were 45%, 8%, 16.21% (p < 0.004) and 9 %, 0%, 0% (p= 0.112 ) respectively. 3 years overall-survival was not statistically different (p= 0.585). However 5 years survival rate and disease-free-survival rate were significantly higher in patients of group A and B (p= 0.003; p< 0.001). CONCLUSION:Treatment strategies to minimize treatment-related morbidity and mortality have resulted satisfactory for early and late outcomes of an heterogeneous group of elderly patients with HCC.

journal_name

Ann Ital Chir

authors

Brozzetti S,Bezzi M,De Sanctis GM,Andreoli GM,De Angelis M,Miccini M,Galati F,Panetta V,Furlan C,De Santis D,De Toma G,Tocchi A

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

120-8

issue

2

eissn

0003-469X

issn

2239-253X

pii

S0003469X13020368

journal_volume

85

pub_type

临床试验,杂志文章
  • [Volvolus in an adult patient due to intestinal malrotation. Case report and review of literature].

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    doi:

    authors: Nardone A,Tamini N,Nespoli L,Pirovano R

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  • Recurrent cystic lymphangioma of the neck. Case report.

    abstract:UNLABELLED:Cystic lymphangioma is a rare benign tumor commonly located in the head or neck. Approximately 100 adult cases have been reported in the literature. The etiopathogenesis is unclear, though trauma has been suggested as one of the possible causes. CASE REPORT:We report a case of recurrent cystic lymphangioma ...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Paladino NC,Scerrino G,Chianetta D,Di Paola V,Gulotta G,Bonventre S

    更新日期:2014-01-01 00:00:00

  • Psoriasis, a rare disease of the nipple-areola A case report.

    abstract:BACKGROUND:Psoriasis is a chronic inflammatory skin disease with an incidence of 1-3%. Psoriasis usually occurs in the scalp, knee, elbow, sacral region and joints. The nipple-areola complex involvement is rarely encountered in the literature. CASE REPORT:31-year-old female patient, who presented at the dermatology ou...

    journal_title:Annali italiani di chirurgia

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    doi:

    authors: Saritas AG,Dalci K,Topal U,Beydola S,Acıkalın A,Rencuuzogullari A

    更新日期:2019-11-10 00:00:00

  • The role of mutation analysis of the APC gene in the management of FAP patients. A controversial issue.

    abstract:BACKGROUND:A correlation between the location of mutation in the adenomatous polyposis coli (APC) gene and clinical manifestations of familial adenomatous polyposis (FAP) has repeatedly been reported. Some Authors suggest the use of mutational analysis as a guide to select the best surgical option in FAP patients. Howe...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Dodaro C,Grifasi C,Florio J,Santangelo ML,Duraturo F,De Rosa M,Izzo P,Renda A

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  • Blunt rectal trauma Case report and literature review.

    abstract::Blunt colorectal traumas are rare clinical entities with a challenging diagnostic and operative management. We describe the case of a 40-year-old man, victim of an accidental fall from a height of four meters who was subsequently diagnosed to have a blunt rectal trauma. A first CT scan showed fracture of the skull and...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Marini M,Fratus G,D'Amore P,Tagliabue F,Mariani P,Spinelli L,Novellino L

    更新日期:2016-12-20 00:00:00

  • [Small cell carcinoma of the esophagus: a case report].

    abstract::The authors present the case of a primitive small cell esophageal carcinoma. It is a rare and biologically aggressive neoplasm which occurs mainly in the elder male. The case observed concerns a 69 year old female treated with surgical therapy consisting in esophagectomy and intrathoracic esophagealgastrictype plasty....

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Tartaglia F,Marzullo A,Marcone P,Stocco F,Marchesi M,Biffoni M,Picchi P,Lentini A,Bernardini E,Nuccio G,Jaus M,Sgueglia M

    更新日期:1997-01-01 00:00:00

  • Vulvar endometriosis and Nuck canal.

    abstract:AIM:Endometriosis is not a well-known disease and sometimes its rare onset is a pathogenetic, diagnostic and therapeutic problem. The Canal of Nuck is an embryonal rest of the parietal peritoneum that accompanies the round ligament through the inguinal canal. The perviousness of the canal of Nuck could explain the path...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Mazzeo C,Gammeri E,Foti A,Rossitto M,Cucinotta E

    更新日期:2014-12-29 00:00:00

  • Pancreatic pseudocyst-inferior vena cava fistula causing caval stenosis, left renal vein thrombosis, subcutaneous fat necrosis, arthritis and dysfibrinogenemia.

    abstract:AIM:We describe the case of a 38 year old man, with a story of alcohol abuse, who developed a very painful nodular subcutaneous fat necrosis, fever and polyarthritis, denying any abdominal symptoms due to a pancreatic pseudocyst-inferior vena cava fistula. MATERIAL OF STUDY:The authors discuss the unusual and protract...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Porcu A,Tilocca PL,Pilo L,Ruiu F,Dettori G

    更新日期:2010-05-01 00:00:00

  • Triplane augmentation mammaplasty.

    abstract:BACKGROUND:Sub-muscular positioning of breast implants requires interrupting as well as disinserting both the abdominal and sterno-chondral fibers of the pectoral muscle; this can produce a muscular strength reduction which reveal bothering and is often detected in some daily motions, such as cutting bread into slices....

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: d'Alcontres FS,Scarcella MC,Colonna MR,d'Alcontres FS,Lupo F

    更新日期:2013-05-01 00:00:00

  • Spleen preserving distal pancreatectomy in isolated pancreatic trauma.

    abstract:INTRODUCTION:Isolated pancreatic trauma is a rare condition and commonly come up in children or young adults.The poor initial symptoms lead to delay diagnosis and treatment. The treatment of isolated distal pancreatic trauma including the Wirsung's duct is generally distal pancreatectomy. In an emergency setting, splen...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Barut B,Ciftci F,Kayaalp C

    更新日期:2017-09-12 00:00:00

  • Laparoscopic drainage of a recurrent psoas abscess.

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Neola B,D'Ambra M,Capasso S,Russo M,Ferulano GP

    更新日期:2014-03-28 00:00:00

  • [Acute torsion of the greater omentum].

    abstract::Primary torsion of the greater omentum is an uncommon cause of acute abdomen and frequently it is misunderstood. In fact, from the analysis of the literature the authors can evict that the preoperative diagnosis is generally wrong. The authors write about the subject and they describe four cases come to their observat...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Di Bartolomeo N,Lanci Lanci C,Marchese E,Staniscia G,Aceto L

    更新日期:1993-01-01 00:00:00

  • [Multinodular goiter as an organ disease: study of continual nodulogenesis. Biological bases indicating total thyroidectomy].

    abstract::Multinodular goitre is a very common pathology among people especially female adult and represents more than 90% of the thyroid surgery. We analyzed 37 patients, demonstrating that the whole gland is progressively affected by an incessant nodulogenesis and we confirm the necessity of total thyroidectomy in order to el...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Giacomelli L,Gagliarducci E,Guerriero G,Feroci D,Ferri S,Iachetta RP,Fabrizio G

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Pio Evoli L,Marino E,Rosati E,Ricci P,Graziosi L,Cavazzoni E,Donini A

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  • [Perforated jejunal diverticulum. A case report].

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    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Basile G,Buffone A,Boscarelli G,Maria S,Santagati G,Corsaro A,Cirino E

    更新日期:2008-01-01 00:00:00

  • Oncoplastic breast-conserving surgery in breast cancer treatment Systematic review of the literature.

    abstract:BACKGROUND:Oncoplastic breast-conserving surgery (OPBS) is a rapidly emerging field. Various oncoplastic techniques have been proposed and are increasingly adopted to facilitate breast conservation and preserve breast aesthetics. This systematic review seeks to assess the oncological and cosmetic outcomes of OPBS. MAT...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Papanikolaou IG

    更新日期:2016-01-01 00:00:00

  • Gastrointestinal Stromal Tumors: a single Center retrospective 15 years study.

    abstract:BACKGROUND:Gastro Intestinal Stromal Tumors (GISTs) are defined as mesenchymal tumours that develop within the wall of the gastrointestinal tract. Surgery is the treatment of choice and may be indicated for locally advanced or previously non resectable disease after a favorable response to preoperative therapy with tyr...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Del Rio P,Bertocchi E,Dell'Abate P,Alberici L,Viani L,Rossi M,Sianesi M

    更新日期:2016-01-01 00:00:00

  • Safe introduction of ancillary trocars in gynecological surgery: the "yellow island" anatomical landmark.

    abstract:AIM:This technical note aims to suggest a safe introduction of ancillary trocars in gynaecological surgery, in order to prevent inferior epigastric artery damage. MATERIAL OF STUDY:We performed a narrative overview, synthesizing the findings of literature retrieved from searches of computerized databases. RESULTS:Amo...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Vitale SG,Gasbarro N,Lagana AS,Sapia F,Rapisarda AMC,Valenti G,Trovato MA,Rossetti D,Chiofalo B,Barrasso G,Tinelli A,Corrado F

    更新日期:2016-01-01 00:00:00

  • Comparison of de novo urinary incontinence after abdominal and vaginal hysterectomy.

    abstract:AIM:This study aimed to compare the frequency and risk factors of de novo urinary incontinence (UI) following abdominal and vaginal hysterectomies for benign disease. METHODS:The study included patients without incontinence history who underwent abdominal or vaginal hysterectomy for benign indications. Incontinence st...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Atakul T,Tayyar AT,Küçük M,Turan ÖD,Özdemir E,Zafer E,Yüksel H

    更新日期:2019-01-01 00:00:00

  • [The effect of the administration of an amino acid solution containing acetate on the calcium balance in surgical patients].

    abstract::A frequent trouble in total parenteral nutrition is the occurrence of a negative calcium balance, due to reduction of calcium tubular reabsorption in acidosis. This condition could depend on acid metabolites raise, coming from degradation of nutritional amino acid mixtures. Authors have evaluated the effect of acetate...

    journal_title:Annali italiani di chirurgia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Ferrari A,Vai L,Nucera R,Fornara G,Cebrelli T,Autelli F,Jemos V,Dionigi P,Zonta A

    更新日期:1993-11-01 00:00:00

  • Risk factors for immediate results and long-term survival following elective open surgery for AAA. Statistical analysis of 1111 consecutively-treated patients.

    abstract:AIM OF THE STUDY:Perioperative and 10 years follow-up risk factors for 1111 consecutive open AAA repairs were statistically analyzed (X2-test and Log-rank test methods for univariate analysis, and logistic regression model and Cox proportional-hazard model for multivariate analysis). Overall operative mortality rate wa...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Bonardelli S,Parrinello G,De Lucia M,Nodari F,Maffeis R,Cervi E,Viotti F,Piardi T,Portolani N,Giulini SM

    更新日期:2007-07-01 00:00:00

  • Good results of surgery for renal cell carcinoma depend on early diagnosis. The need for an extensive screening program.

    abstract:AIM:The aim of our study was to assess the value of several prognostic factors for patients with clear cell renal carcinoma without distant metastases (M0) who underwent surgery in our Department from 1980 to 2010. MATERIAL OF STUDY:We analyzed131 consecutive patients with clear cell renal carcinoma who had nephrectom...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Fiori E,De Cesare A,Crocetti D,Ferraro D,Barmann C,V Sterpetti A,De Toma G

    更新日期:2016-01-01 00:00:00

  • [The classification of biliary calculi and the clinico-therapeutic implications].

    abstract::A new classification of gallstones is reported, which has interesting implications for diagnostic and therapeutic purposes. Gallstones have been divided according to "type" into the following categories: cholesterol (single, multiple), mixed, black pigment, brown pigment, combination and composite. In addition, gallst...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Cetta F

    更新日期:1998-11-01 00:00:00

  • Elastofibroma dorsi. Our experience with 11 lesions.

    abstract::Elastofibroma is a rare benign lesion that typically arises on the posterior chest wall beneath the scapula. The etiopathogenesis is still unclear and the knowledge about its diagnosis and management mainly comes from small case series. We collected all the data related to 11 Elastofibroma Dorsi treated at our institu...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Novati FC,Franchi A,Papa G,Arnež ZM

    更新日期:2014-12-29 00:00:00

  • [The surgery of lung metastases of melanoma].

    abstract::Melanoma is considered one of the most lethal cancers and surgical therapy of its pulmonary metastases is rarely indicated. The only hope for a successful surgical treatment of secondaries from melanoma is a radical resection. Considering the very frequent multiorgan involvement of melanoma metastases, surgery is usua...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Morone G,Meriggi F,Forni E

    更新日期:1998-07-01 00:00:00

  • Association between neuroendocrine tumor of the ileum and two colonic primary malignancies. A case report and review of literature.

    abstract:BACKGROUND:A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy (SPM) has been described in literature and this association can occur either in a synchronous or a metachronous presentation. A wide range of hypothesis has been postulated to explain the high rate of association...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Napolitano L,D'Alessandro V,Risio D,Marinelli C,Cianci R,Innocenti P

    更新日期:2017-10-04 00:00:00

  • [Etiopathogenic, diagnostic and therapeutic problems apropos of 2 observations of acute acalculous cholecystitis].

    abstract::The acute acalculous cholecystitis (A.A.C.) is a disease with high rates of morbidity and mortality and risk and promoting factors are very important. Pathogenesis has not completely explained, diagnosis is difficult, and there is no agreement on the more effective therapy. The authors present two cases of A.A.C. and ...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Bandettini L,Magrini L,Nesi S,Marranci M,Mori S,Pace M

    更新日期:1997-05-01 00:00:00

  • Tension-free hernioplasty: technical remarks and personal experience.

    abstract::The authors report their experience with 463 tension free hernioplasty procedures for inguinal and femoral hernias. The surgical technique included the insertion of both a polypropylene plug and a polypropylene mesh, and was carried out mostly in local anesthesia (84.2%) using bupivacaine 0.25% for ileoinguinal and il...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Civello IM,Frontera D,Pittiruti M,Casale S,Zappalà S,Battista Doglietto G,Zucchetti F,Crucitti F

    更新日期:1997-05-01 00:00:00

  • [Device for intraarterial access for locoregional chemotherapy in hepatic metastasis from colorectal neoplasms (technical note)].

    abstract::Metastasis are the most common malignant lesions of the liver. Liver is the most common site of visceral metastasis from colo-rectal carcinoma. Only in few patients are the lesions surgically resectable for cure and standard intravenous chemotherapy produces a low response rate. An intrahepatic arterial device for reg...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章,评审

    doi:

    authors: Piccinini EE,Ugolini G,Rosati G,Conti A

    更新日期:1994-05-01 00:00:00

  • [Pseudo-occlusions of the internal carotid artery].

    abstract::The pseudo-occlusion (P.O.) of the internal carotid artery is defined as an atheromatous lesion causing a high-grade stenosis, which describes a peculiar angiographic finding ("string sing" or "slim sign"). The authors report their experience with 6 P.O. (angiographically diagnosed) that had been found in 16 months. I...

    journal_title:Annali italiani di chirurgia

    pub_type: 杂志文章

    doi:

    authors: Azzarone M,Berni Canani M,Nahas MA,Benincasa A,Salcuni PF,Tecchio T

    更新日期:1996-09-01 00:00:00