Abstract：
BACKGROUND:A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy (SPM) has been described in literature and this association can occur either in a synchronous or a metachronous presentation. A wide range of hypothesis has been postulated to explain the high rate of association between NETs and SPM, without definitive conclusions. CASE PRESENTATION:We report a case of an ileal neuroendocrine tumor found incidentally at the histologic examination of the surgical specimen in a 72 years old male underwent to right hemi colectomy for two colic adenomatous polips with high grade dysplasia. CONCLUSION:Large multicentric epidemiological studies should be considered to assess the association between NETs and SPM. KEY WORDS:Neuroendocrine tumors (NETs), Progression-Free Survival (PFS), Secondary primary malignancy (SPM). :In letteratura sono stati riportati alcuni casi di associazione tra tumori neuroendocrini (NETs) ed un secondo o più tumori primitivi (SPM). Quest’associazione può presentarsi sia in maniera sincrona che metacrona. Dal punto di vista eziopatogenetico sono state fatte molteplici ipotesi, senza alcuna conclusione definitiva. L’ipotesi più accreditata sostiene l’insorgenza di un secondo tumore in seguito al ruolo carcinogenetico svolto dai peptidi rilasciati dal tumore neuroendocrino Noi riportiamo il caso di un tumore neuroendocrino ileale scoperto incidentalmente all’esame istologico del pezzo operatorio di un uomo di 72 anni sottoposto ad emicolectomia destra per la presenza di due polipi adenomatosi del colon destro con alto grado di displasia. Dovrebbero essere considerati ampi studi epidemiologici multicentrici per caratterizzare meglio e spiegare le cause patogenetiche dell’associazione tra NET ed SPM.
journal_name
Ann Ital Chirjournal_title
Annali italiani di chirurgiaauthors
Napolitano L,D'Alessandro V,Risio D,Marinelli C,Cianci R,Innocenti Psubject
Has Abstractpub_date
2017-10-04 00:00:00eissn
0003-469Xissn
2239-253Xpii
S2239253X17024847journal_volume
6pub_type
杂志文章,评审abstract：:Video-assisted thoracic surgery (VATS) is one of the main medical revolutions of the past decade. For its satisfactory performance, the following prerequisites are essential: (1) knowledge and experience in thoracic surgery; (2) team of experienced anesthesiologists; (3) preoperative assessment of respiratory function...
journal_title：Annali italiani di chirurgia
pub_type： 社论,评审
doi：
更新日期：2000-09-01 00:00:00
abstract：AIM:This study aimed to compare the frequency and risk factors of de novo urinary incontinence (UI) following abdominal and vaginal hysterectomies for benign disease. METHODS:The study included patients without incontinence history who underwent abdominal or vaginal hysterectomy for benign indications. Incontinence st...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2019-01-01 00:00:00
abstract：:Gastric hyperplastic polyps are often asymptomatic and are found incidentally at upper endoscopy performed for unrelated reasons. Although they are considered a benign lesion, all symptomatic polyps should be removed for a more reliable histological diagnosis, resolution of symptoms and to prevent potential malignant ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
abstract：:The authors report the importance of plastic surgery in rehabilitation of the amputated stump. After having referred the tight dependence between amputated stump and prosthesis, they underline the importance of a trophic and painless stump characterized by a satisfactory "useful length". They report two cases in which...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:In the last years the therapeutic behaviour with regard to gastrinomas, has deeply changed becoming more and more aggressive. Nowadays, almost all authors recommend, after a serious treatment of the hypersecretion with omeprazole, an explorative laparatomy in all patients affected by gastrinoma even without a preopera...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:Multiple endocrine neoplasia type 2 (MEN 2) is a rare autosomal dominant cancer syndrome. Forty to fifty percent of patients with MEN 2A develops pheochromocytoma. Surgeons treating these patients with pheochromocytoma have always been faced with question of whether to perform mono-or bilateral adrenalectomy and the t...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-09-01 00:00:00
abstract：AIM:This technical note aims to suggest a safe introduction of ancillary trocars in gynaecological surgery, in order to prevent inferior epigastric artery damage. MATERIAL OF STUDY:We performed a narrative overview, synthesizing the findings of literature retrieved from searches of computerized databases. RESULTS:Amo...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:Near a century after the first successful total gastrectomy for gastric cancer, the authors review the various technical proposals for digestive tract reconstruction following total gastrectomy. Following a classification based on duodenal circuit, on the viscerum employed and on the creation of pouches and/or anti-re...
journal_title：Annali italiani di chirurgia
pub_type： 历史文章,杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：:Elastofibroma is a rare benign lesion that typically arises on the posterior chest wall beneath the scapula. The etiopathogenesis is still unclear and the knowledge about its diagnosis and management mainly comes from small case series. We collected all the data related to 11 Elastofibroma Dorsi treated at our institu...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-12-29 00:00:00
abstract：INTRODUCTION:The majority of neuroendocrine tumors (NET) are located in the gastrointestinal tract (67.5%) and in the bronchopulmonary (25.3%). CASE REPORT:CA, female, 42 years old, profuse diarrhea about two months, cramping for increased peristalsis, vomiting and weight loss. The patient, diagnosed with ileal neuroe...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Fournier's gangrene is a synergistic necrotic fasciitis or myositis of genitalia, perineum and abdominal wall. Several etiologic factors have been reported, microorganisms isolated and co-morbidity factors identified. Immediate and accurate diagnosis decreases mortality rate, which ranges from 3-67%. Aggress...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：:Multiple percutaneous interstitial systems to induce intrahepatic tumor necrosis are classifiable in two major groups: those using chemical agents (ethanol and acetic acid) and those adopting thermal effects (hot saline, radiofrequency, laser and microwave). Indication, technique and results of percutaneous ethanol in...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：INTRODUCTION:The aim of this study is to evaluate the impact of transthoracic endoscopic sympathectomy on plantar hyperhidrosis in patients operated on for upper limb hyperhidrosis. MATERIALS AND METHODS:From 2003 to 2011, 41 consecutive patients underwent videothoracoscopic T3-T4 sympathicotomy or T3-T4 ganglion bloc...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:The aim of this study is to demonstrate the functional capacity of thyroid autografts after total thyroidectomy in a rat model. MATERIALS AND METHODS:60 rats were divided into 6 groups of 10 rats each. Thyroid gland was cut into 0.5 mm pieces and was inserted intramuscularly into the left rectus abdominis m...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:In the period 1992-1997, 211 cases of acute pancreatitis were observed: 81 grave cases; 130 slight cases. The ERCP and endoscopic sphincterotomy were performed in 84 cases. From the critical revision 2 groups of patients emerged, homogeneous for etiology and clinical classification, the first submitted to ERCP within ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The aim of pancreas and islet transplantation is to establish the same status of glucose control that is provided by endogenous secretion of insulin from a healthy native pancreas in order to improve the quality of life and ameliorate secondary diabetic complications in patients with type I insulin-dependent diabetes ...
journal_title：Annali italiani di chirurgia
pub_type： 社论,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:A case of isolated mammary metastasis from surgically untreated urothelial vesical carcinoma is discussed. An integrated chemo-radiotherapeutical treatment had been planned, due to bad general condition; after this, an optimal subjective benefit and good objective response (reduction in lesion diameter < 50%, MR) were...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：INTRODUCTION:Coverage of soft tissue defects in the lower leg is often made by use of free flap, also because of the improving of anaesthesiology techniques in the last decades. However, there are disadvantages in the use of free flaps like the need for a remote donor site, increased operative time, use of a major vess...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：:Remote cerebellar haematoma (RCH) from the operative site is one of the most serious, although extremely rare, complications of spinal surgery. Dural opening is common to every reported case of a spinal procedure complicated by cerebellar hemorrhage, supporting the hypothesis that CSF loss is central to the pathogenes...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：:C. U. T (Chirurgia d'Urgenza Tetraedrica = Tetrahedron Urgent Surgery) is the Data Base programmed and utilized since November 2004 in a "Urgent Surgery Unit" at high turnover of patients and surgeons. The aim of CU. T was to contribute in the management of delivery risk, to facilitate medical work, to improve assiste...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:Cervical radiation for head and neck cancer has been associated with an increased incidence of carotid arterial stenosis. Modern radiation therapy delivers higher doses with increasing long-term survival. In our study 50 patients with head and neck malignancies treated with radiotherapy are analized with colo...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:Carcinoma of the rectal colon begins as a small neoplastic polyp which gradually increases in size and, after passing through various degrees of dysplasia, develops into an overtly malignant carcinoma. Clinical experience suggests that patients may be divided into subgroups based on the aggressivity of the tu...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:The authors report their experience about the clinical significance of the invasion of veins (BVI) in 68 patients with colorectal carcinoma, submitted to potentially curative surgery in the period 1980-1988. Every patient was screened for BVI. The tumoral spreading was differentiated into endovascular and perivascular...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Venous aneurysms are rare lesions and of little significance in every day clinical practice. While in many cases asymptomatic they can be the cause of great morbidity due to thrombosis and subsequent possibility of pulmonary embolism. Venous aneurysms are classified in deep and superficial according to affected vein. ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-10-14 00:00:00
abstract：:The authors review the results of clinical experiences regarding arterial and venous homografts. For the treatment of mycotic aneurysms and infected prostheses, in situ repair with vascular homografts represents a valuable alternative to conventional surgical treatments. In fact the large caliber arterial homografts a...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2001-03-01 00:00:00
abstract：:The association of colorectal cancer and abdominal aortic aneurysm (AAA) is infrequent but poses special problems of priority of treatment under elective circumstances. The purpose of this study was to retrospectively evaluate the outcome of 16 consecutive patients undergoing endovascular aneurysm repair (EVAR) follow...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:A 49-year-old man admitted with a 3 weeks history of stomachache and without any cardiac symptoms and diagnosed as pseudoaneurysm of the left ventricle is reported. The repair was performed with the aid of cardiopulmonary bypass, defect was repaired with Gore-tex patch and myocardial tissues were approximated and clos...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:A dissection of a manometric trace of the upper esophageal sphincter and the crico-esophageal coordination Although manometry is the most accurate method for diagnosing esophageal motility disorders, several patient suffering of high dysphagia remain undiagnosed. Most Authors concentrate their efforts in studying the ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2013-03-01 00:00:00
abstract：AIM:This study analyzes risk factors implicated in postoperative complications and mortality after anterior resection in rectal cancer. MATERIAL AND METHODS:A total number of 378 patients with anterior rectal resection, diagnosed with rectal cancer and admitted at the IIIrd Surgery Clinic, "Octavian Fodor" Regional In...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2017-01-01 00:00:00
abstract：:The Authors report on a case of a 69 years old woman with an acute peritonitis secondary to a perforated jejunal diverticulum, treated by laparotomy and intestinal resection with end-to-end anastomosis in one layer. The patient was dismissed after seven days, in good general conditions. Jejunal diverticula occur in ar...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
