Abstract:
:Multiple endocrine neoplasia type 2 (MEN 2) is a rare autosomal dominant cancer syndrome. Forty to fifty percent of patients with MEN 2A develops pheochromocytoma. Surgeons treating these patients with pheochromocytoma have always been faced with question of whether to perform mono-or bilateral adrenalectomy and the timing of surgical intervention. Over the past 20 years, thanks to the development of ever more sophisticated techniques of diagnostic imaging (TC, MRI, Scintigraphy, PET), which make it possible to identify small lesions, and to ever more rapid laboratory tests, there has been a change in the surgical management of this condition. Surgeons moved from bilateral open adrenalectomy (6- 9) to laparoscopic partial adrenalectomy and cortical sparing (10-13). After partial adrenalectomy one third of the patients require replacement therapy because the function of the residual parenchyma was compromised by excessive devascularization during surgery. In patients with bilateral pheochromocytoma it is advisable to perform only partial adrenalectomy of at least one gland, i.e. to completely remove the gland with the larger lesion and remove part of the gland with the smaller lesion to reduce the risk of recurrence. The authors report 4 cases of MEN 2, including 2 first-degree relatives, which illustrate the progress made in surgical treatment for pheochromocytoma.
journal_name
Ann Ital Chirjournal_title
Annali italiani di chirurgiaauthors
Pedullà G,Crocetti D,Paliotta A,Tarallo MR,De Gori A,Cavallaro G,De Toma Gsubject
Has Abstractpub_date
2014-09-01 00:00:00pages
443-7issue
5eissn
0003-469Xissn
2239-253Xpii
S0003469X14021721journal_volume
85pub_type
杂志文章abstract:AIM OF THE STUDY:To evaluate the role of nuclear medicine techniques in the management of patients with thymoma. MATERIALS AND METHODS:The Authors performed a review of the literature about the usefulness of traditional nuclear medicine and positron emission tomography in patients with thymic tumours. RESULTS AND DIS...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2007-09-01 00:00:00
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2007-07-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2014-03-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
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更新日期:2016-12-20 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
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更新日期:2012-03-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
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更新日期:2005-09-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:1995-09-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2007-05-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Annali italiani di chirurgia
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doi:
更新日期:2011-05-01 00:00:00
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journal_title:Annali italiani di chirurgia
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doi:
更新日期:2012-01-01 00:00:00
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journal_title:Annali italiani di chirurgia
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更新日期:2004-07-01 00:00:00
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journal_title:Annali italiani di chirurgia
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更新日期:2003-01-01 00:00:00
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journal_title:Annali italiani di chirurgia
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更新日期:2001-11-01 00:00:00
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journal_title:Annali italiani di chirurgia
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更新日期:2007-07-01 00:00:00
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journal_title:Annali italiani di chirurgia
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doi:
更新日期:2011-11-01 00:00:00
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journal_title:Annali italiani di chirurgia
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更新日期:2016-01-01 00:00:00
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journal_title:Annali italiani di chirurgia
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
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更新日期:2001-01-01 00:00:00
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journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
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