Abstract：
AIM:The aim of our study was to assess the value of several prognostic factors for patients with clear cell renal carcinoma without distant metastases (M0) who underwent surgery in our Department from 1980 to 2010. MATERIAL OF STUDY:We analyzed131 consecutive patients with clear cell renal carcinoma who had nephrectomy and extended lymph node dissection from 1980 to 2010 were reviewed. Free from cancer survivals were correlated to several prognostic factors including preoperative blood cell count, tumour cellular differentiation and stage of the disease. RESULTS:In our study we confirmed the importance of the stage of the tumour, in particular of the T, as prognostic factor. Survival was strictly correlated to the stage of the disease: 10 year cancer free survival was 100% in patients with T1, 83% in patients with T2 N0 and 34% for patients with T3N0. No improvement of results was noted in the last years, due to unchanged proportion of early diagnosis. DISCUSSION:Long term survival after surgery for clear cell renal carcinoma depends mainly on the histology type of the tumour and on the stage of the disease. Renal carcinoma does not respond to radio and standard chemotherapy and surgery represents the only effective cure. CONCLUSION:Surgery at earlier stages is essential to improve results in patients with renal carcinoma. Earlier diagnosis at the present time is the best possibility to improve results, with the need for extensive use of screening ultrasound test. KEY WORDS:Lymph node dissection in renal carcinoma, Renal carcinoma, Results of surgery for renal carcinoma. :Lo scopo del lavoro è di valutare i fattori prognostici correlati a pazienti sottoposti a chirurgia per tumori renali a cellule chiare, senza metastasi a distanza (M0). Abbiamo analizzato 131 pazienti consecutivi, giunti nel nostro Dipartimento in un periodo compreso tra il 1980 ed il 2010 e affetti da carcinoma a cellule chiare. Tali pazienti sono stati sottoposti ad intervento chirurgico di nefrectomia con dissezione linfonodale estesa. La sopravvivenza libera da malattia è stata correlata a vari fattori prognostici che comprendono il valore emocromocitometrico preoperatorio, la differenziazione cellulare del tumore e lo stage della malattia. La sopravvivenza è strettamente correlata allo staging del tumore: i pazienti con tumori T1 hanno una sopravvivenza a 10 anni pari al 100%, pazienti con staging T2, N0 hanno una sopravvivenza a 10 anni dell’83% e pazienti con staging T3, N0 hanno una sopravvivenza a 10 anni del 34%. La sopravvivenza a distanza dopo chirurgia dipende dal tipo istologico della neoplasia e dallo stading della malattia. La chirurgia negli stadi iniziali è essenziale per migliorare i risultati. La diagnosi precoce, ad oggi è la migliore soluzione per migliorare i risultati.
journal_name
Ann Ital Chirjournal_title
Annali italiani di chirurgiaauthors
Fiori E,De Cesare A,Crocetti D,Ferraro D,Barmann C,V Sterpetti A,De Toma Gsubject
Has Abstractpub_date
2016-01-01 00:00:00pages
41-4eissn
0003-469Xissn
2239-253Xpii
S0003469X16024507journal_volume
87pub_type
杂志文章abstract：:From the beginning of the 60s, Japanese Lung Cancer Society (JLCS) proposed an original TNM classification of lung cancer based on a database of resected cases. The final step was the UICC classification edited in 1973. Complete hilar-mediastinal lymph node dissection was started in the same era and the concept of sta...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：PURPOSE:Haemorrhoids are defined as the distal displacement and venous distention of the normal hemorrhoidal cushions. Multiple factors have been claimed to be causes of hemorrhoidal development, but the exact pathophysiology is poorly understood. The objective of this study was to assess how common is the habit to spe...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2020-01-01 00:00:00
abstract：:Biliary papillomatosis is a disease characterized by multiple papillary tumours of variable distribution and extent in the intrahepatic and/or extrahepatic biliary tree. Papillary carcinoma can develop within these lesions. Because biliary papillomatosis is a rare biliary pathological entity, its clinical features and...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
abstract：:Meckel's diverticulum (MD ) is the most common congenital anomaly of the gastrointestinal tract. We revalued clinical records of patients discharged from Unit of Urgent and General Surgery of Highly Specialized Hospital "A.O.R.N. Antonio Cardarelli" of Naples with diagnosis of acute pathology associated to complicated...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:A case of duodenal diverticulum complication (cholangiopancreatitis) in a patient of 62 years old is reported. It has been treated successfully by endoscopic sphincterotomy technique. ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:In the last ten years etiology's frequency of non-neoblastic bowel occlusions has changed. Headway against occlusions percentage decreasing due to post-operative stenosis, hernial strangulation, adhesional bridles, etc., mechanical ileus observations increase in percentage round about 20%, as colon acquired diverticul...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：OBJECTIVE:Acetaminophen is effective for acute surgical pain, but whether it reduces persistent incision pain remains unknown. We tested the primary hypothesis that patients given perioperative acetaminophen have less incisional pain three months after surgery. Our secondary hypotheses were that patients randomized to ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2018-05-15 00:00:00
abstract：:This case report describes an acute colonic diverticular perforation occurred to a multiple myeloma patient, taking corticosteroid and morphine therapy, revealed by a subcutaneous emphysema of upper chest and right abdomen as initial presentation. Sigmoid diverticulitis with perforation and generalized peritonitis is ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:The Bariatric Analysis and Reporting Outcome System (BAROS) has been recently introduced to assess the modifications of weight, comorbidities and quality of life (QOL) after bariatric surgery, in order to achieve a standard for comparison in the treatment of obesity. This study reports the Authors' experienc...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:Hemosuccus pancreaticus is a rare clinical condition, defined as a bleeding from an artery around the pancreas or a lesion on the pancreas, to the pancreatic duct. The intensity of bleeding can vary from occult bleeding to life threatening massive acute bleeding. In this article, we aimed to present a 68-year-old man ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2020-01-01 00:00:00
abstract：:Hereditary spherocytosis (HS) is a common inherited hemolytic anemia caused by a defective erythrocyte cellular membrane. Irrespective of type of surgery performed, several case reports comparing the two type of procedures, have not proven any significant difference between serum bilirubin, serum hemoglobin, red blood...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2018-01-01 00:00:00
abstract：:Hepatic metastases are a major cause of death in patients with colorectal carcinoma. Traditional intravenous chemotherapy produces responses in 10% to 30% of patients and surgical resection is feasible in approximately 20% of patients. Infusion of cytotoxic agents into the hepatic artery is the most promising form of ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：1996-11-01 00:00:00
abstract：AIM:To evaluate accuracy of endorectal ultrasonography (ERUS) both in staging and restaging rectal cancer after neoadjuvant chemoradiotherapy treatment. METHODS:In a group of 80 patients with rectal cancer, we retrospectively selected 67 patients and divided in two groups: 41 patients affected by a stage I were invest...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：:The authors present the case of a primitive small cell esophageal carcinoma. It is a rare and biologically aggressive neoplasm which occurs mainly in the elder male. The case observed concerns a 69 year old female treated with surgical therapy consisting in esophagectomy and intrathoracic esophagealgastrictype plasty....
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:The Authors report their experience in diagnosis and treatment of one case of primary low-grade gastric lymphoma of mucosa associated lymphoid tissue (MALT); recent international literature review. EXPERIMENTAL DESIGN:Complete clinical report. Diagnostic, clinical and prognostic indication, evaluation of eff...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:Thyroid surgery is a clean procedure and therefore antibiotic prophylaxis is not routinely recommended by most international guidelines. However, antibiotics are often used in clinical practice. We enrolled 2926 patients who performed a thyroid surgical operation between the years 2009 and 2011 in the 38 centers of en...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章,多中心研究
doi：
更新日期：2014-01-01 00:00:00
abstract：:By long experience with the problems on hiatal hernias and reflux the author summarizes and analyzes errors and progress in development, interpretation, diagnostic methods and treatment. After the pioneer work done by Akerlund 1926 the hiatal hernia was a sometimes dangerous surgical target. It remained for a long tim...
journal_title：Annali italiani di chirurgia
pub_type： 社论,评审
doi：
更新日期：1993-05-01 00:00:00
abstract：INTRODUCTION:The aim of this study is to evaluate the impact of transthoracic endoscopic sympathectomy on plantar hyperhidrosis in patients operated on for upper limb hyperhidrosis. MATERIALS AND METHODS:From 2003 to 2011, 41 consecutive patients underwent videothoracoscopic T3-T4 sympathicotomy or T3-T4 ganglion bloc...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:Malignant ascites is an abnormal accumulation of fluid in the peritoneal cavity of patients with intraperitoneal cancer dissemination. This clinical condition could represent the terminal evolution of a lethal disease and could influence the prognosis, severely impairing the patients' quality of life. Treatment option...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to review the characteristics, intraoperative and radiological findings of abdominal wall endometriosis (AWE). METHODS:This retrospective observational cohort study was executed through analysis of the medical records of patients who underwent excision of AWE between January 2000 and...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2018-01-01 00:00:00
abstract：AIM:Retrospective review of aorto-iliac infections in a single vascular surgery center. METHODS:From a retrospective review of their experience in the last 20 years, the Authors analyze a series of 12 cases of aorto-iliac infection. Prognostic factors, surgical options and results are discussed and compared with the l...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2011-11-01 00:00:00
abstract：:İNTRODUCTION : Angiomyxoma is a rare slow-growing soft tissue myxoid cell tumor that usually arises in the pelvis and perineal regions and occurs predominantly in women in the fourth decade. Angiomyxomas usually present as often initially misdiagnosed asymptomatic masses. Most common clinical early diagnoses of aggres...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2019-11-10 00:00:00
abstract：:The aim of pancreas and islet transplantation is to establish the same status of glucose control that is provided by endogenous secretion of insulin from a healthy native pancreas in order to improve the quality of life and ameliorate secondary diabetic complications in patients with type I insulin-dependent diabetes ...
journal_title：Annali italiani di chirurgia
pub_type： 社论,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:The authors report the importance of plastic surgery in rehabilitation of the amputated stump. After having referred the tight dependence between amputated stump and prosthesis, they underline the importance of a trophic and painless stump characterized by a satisfactory "useful length". They report two cases in which...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Intracranial epidermoid cysts are estimated to constitute 0.2 to 1.8% of brain tumours (4) and they can be divided into four categories describing their anatomic origin and frequent primary location: retro-sellar-cerebellopontine angle, parasellar-sylvian fissure, suprasellar-chiasmatic and basilar-posterior fossa. We...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:Esophageal anastomotic leaks are associated with significant morbidity and mortality. The purpose of this study was to retrospectively assess the role of the anastomotic positioning (thoracic or cervical) on the incindence of the anastomotic leak and its severity. METHODS:In the period 2002-07, we have perfo...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Cervical carotid dissection is more common in extracranical vessel: internal carotid artery dissection (ICAD) is typical, vertebral artery dissection is uncommon, common carotid artery dissection (CCAD) is rare and even a more rare cause of ischemic stroke. Cervical artery dissections account up to 20-25% of...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2014-09-18 00:00:00
abstract：:The acute acalculous cholecystitis (A.A.C.) is a disease with high rates of morbidity and mortality and risk and promoting factors are very important. Pathogenesis has not completely explained, diagnosis is difficult, and there is no agreement on the more effective therapy. The authors present two cases of A.A.C. and ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:Gastric hyperplastic polyps are often asymptomatic and are found incidentally at upper endoscopy performed for unrelated reasons. Although they are considered a benign lesion, all symptomatic polyps should be removed for a more reliable histological diagnosis, resolution of symptoms and to prevent potential malignant ...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:The authors report their experience about the treatment of two cases of gastric bezoar, treated in curative mode, the first endoscopically and the second with surgical intervention. SETTING:Operative Unit of General and Thoracic Surgery, Department of General and Emergency Surgery, Organ Transplantation, Pol...
journal_title：Annali italiani di chirurgia
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
