Abstract:
:A striking behavioral abnormality is described in three individuals who had severe head trauma. At a point when general mnestic capabilities had returned to a near normal level, the patients persistently relocated the hospital at another geographical site, even in the face of compelling counter-evidence. The strong parallels in the etiology and course of the three cases justify the positing of a syndrome, here termed reduplicative paramnesia. A neuropsychologic analysis of the disorder stresses the cognitive operations entailed in geographical localization and confabulation. Clinical-pathologic considerations underline the role of right hemisphere and frontal lobe structures in the syndrome.
journal_name
Neurologyjournal_title
Neurologyauthors
Benson DF,Gardner H,Meadows JCdoi
10.1212/wnl.26.2.147subject
Has Abstractpub_date
1976-02-01 00:00:00pages
147-51issue
2eissn
0028-3878issn
1526-632Xjournal_volume
26pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::Adult-onset dystonia-parkinsonism is a syndrome in search of a pathology. We therefore reviewed the literature on dystonic manifestations in autopsy-proven cases of multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and idiopathic Parkinson's disease (PD). Only 6 of 140 autopsy reports of MSA remarke...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.40.10.1571
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:The 36-item Short Form Health Survey Questionnaire (SF-36) is a widely used generic health status measure. Recently it has been adapted to produce a disease-specific measure for MS-the 54-item Multiple Sclerosis Quality of Life Scale (MSQOL-54)-composed of five unchanged SF-36 scales; three altered SF-36 scal...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.1.68
更新日期:2001-07-10 00:00:00
abstract:OBJECTIVE:The purpose of this cross-sectional study was to determine the prevalence and potential significance of stroke symptoms among end-stage renal disease (ESRD) patients without a prior diagnosis of stroke or TIA. METHODS:We enrolled 148 participants with ESRD from 5 clinics. Stroke symptoms and functional statu...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31826845e9
更新日期:2012-09-04 00:00:00
abstract::The major glycoprotein P0 from human and bovine peripheral nerves carries the L2/HNK-1 and L3 carbohydrate epitopes and is recognized by serum from patients with IgM gammopathy and polyneuropathy. Only serum from patients with reactivity toward the myelin-associated glycoprotein (MAG) was reactive with P0, while serum...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.8.1266
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:There is a paucity of therapies for gait impairment in Parkinson disease (PD). Open-label studies have suggested improved gait after treatment with methylphenidate (MPD). OBJECTIVE:To evaluate the efficacy of MPD for the treatment of gait impairment in PD. METHODS:Twenty-seven subjects with PD and moderate...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/WNL.0b013e3182143537
更新日期:2011-04-05 00:00:00
abstract::We treated 64 emergency room patients with a primary vascular headache with dihydroergotamine (DHE), meperidine, or butorphanol. Post-treatment pain scores were lowest in the DHE group (p less than 0.01). Eight of 21 patients receiving DHE had greater than 90% reduction in pain compared with three of 19 patients recei...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.39.4.590
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:Studies have suggested that mood status is associated with an increased risk of stroke, though mostly based on measures of depression defined by symptoms alone rather than diagnostic criteria representative of clinically important distress and impairment. We investigated this association based upon a large p...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000304109.18563.81
更新日期:2008-03-04 00:00:00
abstract::This study reports the results of a prospective trial of nonoperative management of the cubital tunnel syndrome in 128 patients. Forty-three of the patients had bilateral ulnar nerve compression. At study's end, information was available on 94% of patients and 164 managed extremities, at a mean of 58.6 months of follo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.9.1673
更新日期:1993-09-01 00:00:00
abstract::We studied the effect of deep brain stimulation (DBS) of the ventral intermediate thalamic nucleus on voice symptoms in seven patients with essential tremor. All had undergone DBS for management of hand tremor. Five of the patients had received unilateral implants; two were treated bilaterally. Each reported improveme...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.50.3.796
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To investigate botulinum toxin (BTX) effects on central and peripheral motor excitability in writer's cramp. METHODS:Using transcranial magnetic stimulation over the motor cortex and brainstem and peripheral electrical stimulation, the authors investigated measures of motor cortical and peripheral motor exci...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000095965.36574.0f
更新日期:2003-12-09 00:00:00
abstract::The blink reflex may be evoked by auditory click or light stimulation, the latter being constantly present in all healthy subjects. The latency and amplitude of the light-stimulus-evoked blink response (L-BR) is influenced by the light intensity, distance between the light stimulus and the eye, attention, and backgrou...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.31.3.272
更新日期:1981-03-01 00:00:00
abstract::We developed a scheme using routinely available data to estimate the risk of human immunodeficiency virus (HIV) dementia in HIV-infected persons over time. We performed a longitudinal review of medical records from more than 100 medical facilities in 11 U.S. cities. A total of 19,462 HIV-infected persons without histo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.2.392
更新日期:1998-02-01 00:00:00
abstract::We studied two unrelated patients with autosomal recessive multisystem triglyceride storage disease. Cultured fibroblasts accumulated 10 times more triglyceride than controls under glycerol or palmitate feeding. Mutant fibroblasts could not degrade accumulated triglycerides of endogenous origin, but normally degraded ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.7.1107
更新日期:1988-07-01 00:00:00
abstract::In thymomas associated with myasthenia gravis (MG), the authors found that perivascular infiltrates of memory lymphocytes and mature dendritic cells (DCs) were more frequent in patients with early improvement after thymectomy than in patients without response to thymectomy. Although these findings may be limited to pa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000174560.35190.84
更新日期:2005-09-13 00:00:00
abstract::The authors describe two novel mutations of the acid alpha-glucosidase gene, P361L and R437C, which define the juvenile-onset glycogen storage disease type II (GSDII) in a 16-year-old Chinese patient. The asymptomatic 13-year-old brother of the proband is also a compound heterozygote of the two mutations. These result...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000048661.95327.bf
更新日期:2003-02-25 00:00:00
abstract::Pathology and imaging studies have shown that patients with Parkinson disease (PD) have a prolonged period of uncertain duration when vulnerable neuronal populations are degenerating, but typical motor symptoms have not yet developed. This provides both an opportunity-it may be best to test new medications and, ultima...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0b013e318198df97
更新日期:2009-02-17 00:00:00
abstract::Intramedullary cysticercosis of the spinal cord is rare; there have been only 26 previous cases. We describe a patient with low back pain, paraparesis, lumbosacral sensory loss, and signs of meningeal irritation. The clinical diagnosis was spinal cord tumor, but at surgery there was a cysticercus cyst within the lumbo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.29.11.1531
更新日期:1979-11-01 00:00:00
abstract:OBJECTIVE:To determine whether increased risk of acute ischemic stroke (AIS) following herpes zoster (HZ) might be modified by the status of zoster vaccine live (ZVL) vaccination and antiviral treatment following HZ. METHODS:We included 87,405 Medicare fee-for-service beneficiaries aged ≥66 years diagnosed with HZ and...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000010028
更新日期:2020-08-11 00:00:00
abstract:OBJECTIVE:To characterize patterns of cognitive functioning in a well-defined group of patients with MRI-identified coexisting left temporal lobe developmental malformations (TLDM) and mesial temporal sclerosis (MTS), and to examine neuropsychological outcome in this dual-pathology group following epilepsy surgery. ME...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.53.4.709
更新日期:1999-09-11 00:00:00
abstract:OBJECTIVE:To investigate the effect of postoperative delirium on longitudinal brain microstructural changes, as measured by diffusion tensor imaging. METHODS:We studied a subset of the larger Successful Aging after Elective Surgery (SAGES) study cohort of older adults (≥70 years) without dementia undergoing elective s...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004329
更新日期:2017-09-05 00:00:00
abstract::A new generation of Atraumatic (blunt tipped) needles now exists in addition to the traditional Quincke (cutting tip) needles for LP. We wished to identify the optimal size and type of needle that should be used for this technique. Requirements include rapid and accurate transduction of CSF pressure and adequate flow ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.47.1.33
更新日期:1996-07-01 00:00:00
abstract::Postmortem studies of patients with progressive supranuclear palsy (PSP) have demonstrated loss of cholinergic neurons in the striatum, nucleus basalis of Meynert, and the pedunculopontine nucleus. These findings suggest that cholinergic drugs might be an effective treatment for this disease. We studied the efficacy o...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.39.2.257
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVE:To report a case of Lambert-Eaton myasthenic syndrome (LEMS) in a child and review the existing literature of LEMS in children. METHODS:We report a pediatric case of LEMS with the classic clinical triad of proximal weakness, autonomic dysfunction, and areflexia; the characteristic increment in compound motor...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0b013e318293e14e
更新日期:2013-05-21 00:00:00
abstract:OBJECTIVE:To identify presurgical and postsurgical factors that are independently predictive of the outcome of anterior temporal lobectomy (ATL) for intractable epilepsy. BACKGROUND:There have been reports of prognostic factors in epilepsy surgery, but little is known about factors that independently predict outcome o...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.2.465
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:The state-of-the-art tools of neurology, in particular modern neuroimaging techniques, have yet to benefit from the revolution in mobile technologies that provide new insights into the mechanisms underlying clinical syndromes. This study demonstrates the manner in which mobile technologies may provide informa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31824528b2
更新日期:2012-01-31 00:00:00
abstract::Hippocampal sclerosis dementia (HSD) is a disease of unknown etiology and pathogenesis. To determine whether HSD cases could be reclassified as variants of frontotemporal dementia (FTD), a heterogeneous group of disorders, 18 brain autopsy cases previously diagnosed as HSD were re-evaluated. In 11 cases, ubiquitinated...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/01.wnl.0000129543.46734.c0
更新日期:2004-08-10 00:00:00
abstract:BACKGROUND:Patients with Parkinson disease (PD) may present with various types of pain. In some instances, no cause can be identified and pain is considered a primary disorder (primary central pain [PCP]). We hypothesized that PCP in patients with PD (PD-PCP) may be due to a dysfunction of pain pathways or the processi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000295669.12443.d3
更新日期:2007-12-04 00:00:00
abstract:OBJECTIVE:To determine black-white differences in 1-year recurrent stroke and 30-day case fatality after a recurrent stroke in older US adults. METHODS:We conducted a retrospective cohort study using a 5% random sample of Medicare beneficiaries with fee-for-service health insurance coverage who were hospitalized for i...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006467
更新日期:2018-11-06 00:00:00
abstract:OBJECTIVE:To determine the efficacy and tolerability of unilateral thalamic deep brain stimulation (DBS) for patients with medically refractory essential tremor (ET) and the tremor associated with Parkinson's disease (PD). BACKGROUND:The tremor of ET and PD may produce functional disability despite optimal medical the...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.51.4.1063
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to clarify the characteristic brain MRI findings for genetically diagnosed CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy). METHODS:Seven patients with CARASIL carrying HTRA1 mutations (representing 6 Japanese families) we...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001803
更新日期:2015-08-04 00:00:00