Is the cytologic diagnosis of esophageal glandular dysplasia feasible?

Abstract:

:Barrett's esophagus is a premalignant condition in which the normal stratified squamous epithelium of the esophagus is replaced by metaplastic glandular epithelium. Patients with Barrett's esophagus are at increased risk for the development of esophageal adenocarcinoma. Because dysplasia precedes the development of frank adenocarcinoma, the cytologic detection of esophageal glandular dysplasia represents a potentially inexpensive and efficient means of monitoring disease progression to adenocarcinoma and identifying high-risk patients. This article discusses the current status of exfoliative cytology as a screening test for glandular dysplasia of the esophagus.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Hughes JH,Cohen MB

doi

10.1002/(sici)1097-0339(199804)18:4<312::aid-dc13>

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

312-6

issue

4

eissn

8755-1039

issn

1097-0339

pii

10.1002/(SICI)1097-0339(199804)18:4<312::AID-DC13>

journal_volume

18

pub_type

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