Hemodynamic derangement for the induction of cerebrovascular fat deposition in normotensive rats on a hypercholesterolemic diet.

abstract：BACKGROUND AND PURPOSE:Inflammation is thought to be a major contributor to carotid artery disease. Lipopolysaccharide (LPS) activates inflammatory mechanisms thought to contribute to endothelial dysfunction by mechanisms that are not well defined. The goal of this study was to determine whether overexpression of CuZn-...

journal_title：Stroke

authors： Didion SP,Kinzenbaw DA,Fegan PE,Didion LA,Faraci FM

更新日期：2004-08-01 00:00:00

abstract：:Background and Purpose- Recanalization with tPA (tissue-type plasminogen activator) is the only pharmacological therapy available for patients with ischemic stroke. However, the percentage of patients who may receive this therapy is limited by the risk of hemorrhagic transformation (HT)-the main complication of ischem...

journal_title：Stroke

authors： García-Yébenes I,García-Culebras A,Peña-Martínez C,Fernández-López D,Díaz-Guzmán J,Negredo P,Avendaño C,Castellanos M,Gasull T,Dávalos A,Moro MA,Lizasoain I

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion magnetic resonance imaging (MRI) can quantitatively detect focal ischemic injury within minutes of onset, and perfusion MRI can evaluate the brain's microcirculation. N-Methyl-D-aspartate (NMDA) antagonists and reperfusion can reduce lesion size in stroke models. We used diffusion and p...

journal_title：Stroke

authors： Minematsu K,Fisher M,Li L,Sotak CH

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebrovascular reserve (CVR) by both transcranial Doppler ultrasonography (TCD) and quantitative cerebral blood flow (CBF) can identify subgroups of patients at increased risk for stroke. A direct comparison of CVR measurements obtained with both technologies in patients with cerebrovascular occ...

journal_title：Stroke

authors： Pindzola RR,Balzer JR,Nemoto EM,Goldstein S,Yonas H

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:the Penumbra Pivotal Stroke Trial reported a 25% good outcome (modified Rankin scale score ≤ 2) despite an 81% recanalization rate. We evaluated the association of a favorable initial noncontrast CT and a short time to recanalization in predicting good outcome. METHODS:data were from the Penumbr...

journal_title：Stroke

authors： Goyal M,Menon BK,Coutts SB,Hill MD,Demchuk AM,Penumbra Pivotal Stroke Trial Investigators, Calgary Stroke Program, and the Seaman MR Research Center.

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The independent contribution of insulin resistance to atherosclerosis is still under debate. We compared associations of 2 different indices of insulin resistance, the Homeostasis Model Assessment (HOMA) index and kITT from a short insulin tolerance test with carotid atherosclerosis. METHODS:A t...

journal_title：Stroke

authors： Sourij H,Schmoelzer I,Dittrich P,Paulweber B,Iglseder B,Wascher TC

更新日期：2008-04-01 00:00:00

abstract：:The etiology of cerebrovascular disease (CDV) in young patients is difficult to establish if the common causes of a focal neurological deficit are excluded by appropriate investigations. Since in some observations prolapse of the mitral-valve (MVP), alterations of platelet function, or both have been linked with cereb...

journal_title：Stroke

authors： Scharf RE,Hennerici M,Bluschke V,Lueck J,Kladetzky RG

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the leading cause of adult disability worldwide. Currently, there is no effective treatment for stroke survivors. Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are the growth factors regulating hematopoiesis. We have previously observed that SCF and G-CSF have...

journal_title：Stroke

authors： Zhao LR,Berra HH,Duan WM,Singhal S,Mehta J,Apkarian AV,Kessler JA

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Epidemiological studies have shown mixed findings on the association between hypertension and stroke in the oldest old. Heterogeneity of the populations under study may underlie variation in outcomes. We examined whether the level of physical and cognitive function moderates the association betwe...

journal_title：Stroke

authors： Sabayan B,van Vliet P,de Ruijter W,Gussekloo J,de Craen AJ,Westendorp RG

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ABC/2 method for calculating intracerebral hemorrhage (ICH) volume has been well validated. However, the formula, derived from the volume of an ellipse, assumes the shape of ICH is elliptical. We sought to compare the agreement of the ABC/2 formula with other methods through retrospective ana...

journal_title：Stroke

authors： Haley MD,Gregson BA,Mould WA,Hanley DF,Mendelow AD

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute cocaine use has been temporally associated with aneurysmal subarachnoid hemorrhage (aSAH). This study analyzes the impact of cocaine use on patient presentation, complications, and outcomes. METHODS:Data of patients admitted with aSAH between 1991 and 2009 were reviewed to determine impact...

journal_title：Stroke

authors： Chang TR,Kowalski RG,Caserta F,Carhuapoma JR,Tamargo RJ,Naval NS

更新日期：2013-07-01 00:00:00

abstract：:In a group of 48 patients with completed stroke, 8 patients had viable collaterally perfused brain tissue which was accessible for rCBF recordings with a two dimensional technique. All 8 had deep subcortical infarcts on CT-scan, and angiographic occlusion of the arteries normally supplying the infarcted territory. The...

journal_title：Stroke

authors： Olsen TS,Larsen B,Herning M,Skriver EB,Lassen NA

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hypothermia reduces neuronal damage in animal stroke models. Whether hypothermia is neuroprotective in patients with acute stroke remains to be clarified. In this case-control study, we evaluated the feasibility and safety of inducing modest hypothermia by a surface cooling method in awake patien...

journal_title：Stroke

authors： Kammersgaard LP,Rasmussen BH,Jørgensen HS,Reith J,Weber U,Olsen TS

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cavernous malformations of the brain (CMs) cause intracranial hemorrhage, but its reported frequency varies, partly attributable to study design. To improve the validity of future research, we aimed to develop a robust definition of CM hemorrhage. METHODS:We systematically reviewed the published...

journal_title：Stroke

authors： Al-Shahi Salman R,Berg MJ,Morrison L,Awad IA,Angioma Alliance Scientific Advisory Board.

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain microbleeds (MBs) are considered to be associated with cognitive decline and can be pathologically and topographically classified as cerebral amyloid angiopathy-related (located in lobar regions) and hypertensive microangiopathy-related (located in deep regions). We examined whether differe...

journal_title：Stroke

authors： Yakushiji Y,Noguchi T,Hara M,Nishihara M,Eriguchi M,Nanri Y,Nishiyama M,Hirotsu T,Nakajima J,Kuroda Y,Hara H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Exogenous delivery of vascular endothelial growth factor gene (VEGF) may provide a useful approach to the treatment of brain ischemia. We investigated the use of a hypoxia-responsive element to control VEGF expression given for neuroprotection. METHODS:Three groups (n=36) of mice received AAVH9-...

journal_title：Stroke

authors： Shen F,Su H,Fan Y,Chen Y,Zhu Y,Liu W,Young WL,Yang GY

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some clinical models, like California ABCD and unified ABCD2 scores, are now available to predict the early risk of stroke after a TIA. Despite the transitivity of symptoms, DWI identified an area of acute brain ischemia in almost half of patients. It would be interesting to know how the presence...

journal_title：Stroke

authors： Purroy F,Begué R,Quílez A,Piñol-Ripoll G,Sanahuja J,Brieva L,Setó E,Gil MI

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spontaneous dissection of the cervical internal carotid artery (sICAD) is mainly assessed with MRI and magnetic resonance angiography (MRA), which are not always at hand. In contrast, color duplex sonography (CDS) is readily available. We undertook this prospective study to examine the accuracy o...

journal_title：Stroke

authors： Benninger DH,Georgiadis D,Gandjour J,Baumgartner RW

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To identify if the stroke-prone spontaneously hypertensive rat (SHRSP) exhibits impaired functional recovery after stroke compared with its normotensive reference strain, the Wistar Kyoto rat (WKY). METHODS:In study 1, a 2-mm distal middle cerebral artery occlusion (middle cerebral artery occlus...

journal_title：Stroke

authors： McGill JK,Gallagher L,Carswell HV,Irving EA,Dominiczak AF,Macrae IM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Hyperpolarization of vascular muscle in response to activation of potassium channels is a major mechanism of vasodilatation. In cerebral blood vessels, four different potassium channels have been described: ATP-sensitive potassium channels, calcium-activated potassium channels, delayed rectifier potassium ch...

journal_title：Stroke

authors： Kitazono T,Faraci FM,Taguchi H,Heistad DD

更新日期：1995-09-01 00:00:00

abstract：:Feline pial arteries larger than 100 mu in diameter constricted in response to cervical sympathetic nerve stimulation suggests or in response to topical application of norepinephrine. Smaller pial arteries were unresponsive to norepinephrine. This unresponsiveness persisted when norepinephrine was dissolved in CSF wit...

journal_title：Stroke

authors： Wei EP,Raper AJ,Kontos HA,Patterson JL Jr

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aspirin resistance may be relatively common and associated with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the lowest effective dose; however, it is not known whether the recent increased use of enteric-coated aspirin could account for aspirin resistance. This st...

journal_title：Stroke

authors： Cox D,Maree AO,Dooley M,Conroy R,Byrne MF,Fitzgerald DJ

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial color-coded sonography is a new development in noninvasive cerebral vascular imaging. Reference data using this technique are described. METHODS:Blood velocities and pulsatility and resistance indices were determined in the anterior cerebral, middle cerebral, posterior cerebral, ver...

journal_title：Stroke

authors： Martin PJ,Evans DH,Naylor AR

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Stroke Health and Risk Education Project was a cluster-randomized, faith-based, culturally sensitive, theory-based multicomponent behavioral intervention trial to reduce key stroke risk factor behaviors in Hispanics/Latinos and European Americans. METHODS:Ten Catholic churches were randomize...

journal_title：Stroke

authors： Brown DL,Conley KM,Sánchez BN,Resnicow K,Cowdery JE,Sais E,Murphy J,Skolarus LE,Lisabeth LD,Morgenstern LB

更新日期：2015-10-01 00:00:00

abstract：:Many patients suffer a stroke early after a transient ischemic attack, but the reason why is often unclear. We studied 12 patients with less than 75% stenosis of the internal carotid artery and a single hemispheric transient ischemic attack lasting less than 1 hour who had a normal neurologic examination 3-13 hours la...

journal_title：Stroke

authors： Bogousslavsky J,Delaloye-Bischof A,Regli F,Delaloye B

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. The roles that reproductive steroi...

journal_title：Stroke

authors： Shearman AM,Cooper JA,Kotwinski PJ,Humphries SE,Mendelsohn ME,Housman DE,Miller GJ

更新日期：2005-10-01 00:00:00

abstract：:Background and Purpose- High-resolution vessel wall magnetic resonance imaging is a promising technique for assessing wall structures of unruptured intracranial aneurysms (UIAs). However, the relationship between aneurysmal high-resolution vessel wall magnetic resonance imaging features and their histopathologic mecha...

journal_title：Stroke

authors： Quan K,Song J,Yang Z,Wang D,An Q,Huang L,Liu P,Li P,Tian Y,Zhou L,Zhu W

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:[18F]fluoromisonidazole (FMISO) positron emission tomography has been used to image hypoxia early after human stroke. To further study the role of hypoxia in stroke and the binding characteristics of FMISO, we aimed to develop [3H]FMISO autoradiography in an animal stroke model. We hypothesized t...

journal_title：Stroke

authors： Spratt NJ,Ackerman U,Tochon-Danguy HJ,Donnan GA,Howells DW

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stent-assisted coiling has expanded the treatment of intracranial aneurysms, but the rates of procedure-related neurological complications and the incidence of angiographic aneurysm recurrence of this novel treatment are not yet well known. We present our experience with stent-assisted coiling wi...

journal_title：Stroke

authors： Piotin M,Blanc R,Spelle L,Mounayer C,Piantino R,Schmidt PJ,Moret J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately one fourth of stroke occur during sleep. Despite the clinical and radiological similarities between wake-up stroke (WUS) and non-WUS, the functional outcomes of WUS are largely unknown. METHODS:This retrospective analysis reviewed 2289 consecutive patients with acute ischemic strok...

journal_title：Stroke

authors： Kim BJ,Lee SH,Shin CW,Ryu WS,Kim CK,Yoon BW

更新日期：2011-07-01 00:00:00