Disparities in revascularization rates after acute myocardial infarction between aboriginal and non-aboriginal people in Australia.


BACKGROUND:This study examined revascularization rates after acute myocardial infarction (AMI) for Aboriginal and non-Aboriginal patients sequentially controlling for admitting hospital and risk factors. METHODS AND RESULTS:Hospital data from the state of New South Wales, Australia (July 2000 through December 2008) were linked to mortality data (July 2000 through December 2009). The study sample were all people aged 25 to 84 years admitted to public hospitals with a diagnosis of AMI (n=59 282). Single level and multilevel Cox regression was used to estimate rates of revascularization within 30 days of admission. A third (32.9%) of Aboriginal AMI patients had a revascularization within 30 days compared with 39.7% non-Aboriginal patients. Aboriginal patients had a revascularization rate 37% lower than non-Aboriginal patients of the same age, sex, year of admission, and AMI type (adjusted hazard ratio, 0.63; 95% confidence interval, 0.57-0.70). Within the same hospital, however, Aboriginal patients had a revascularization rate 18% lower (adjusted hazard ratio, 0.82; 95% confidence interval, 0.74-0.91). Accounting for comorbidities, substance use and private health insurance further explained the disparity (adjusted hazard ratio, 0.96; 95% confidence interval, 0.87-1.07). Hospitals varied markedly in procedure rates, and this variation was associated with hospital size, remoteness, and catheterization laboratory facilities. CONCLUSIONS:Aboriginal Australians were less likely to have revascularization procedures after AMI than non-Aboriginal Australians, and this was largely explained by lower revascularization rates at the hospital of first admission for all patients admitted to smaller regional and rural hospitals, a higher comorbidity burden for Aboriginal people, and to a lesser extent a lower rate of private health insurance among Aboriginal patients.






Randall DA,Jorm LR,Lujic S,O'Loughlin AJ,Eades SJ,Leyland AH




Has Abstract


2013-02-19 00:00:00














  • Effects of nifedipine on systemic and regional oxygen transport and metabolism at rest and during exercise.

    abstract::In a placebo-controlled, randomized, cross-over, double-blind study of 12 patients with stable exertional angina, we measured at rest and during bicycle exercise the effects of 20 mg of nifedipine administered sublingually on hemodynamics and systemic and regional oxygen extraction and metabolism. Nifedipine decreased...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Choong CY,Roubin GS,Shen WF,Harris PJ,Kelly DT

    更新日期:1985-04-01 00:00:00

  • Calcium antagonists and hypothermia: the temperature dependency of the negative inotropic and anti-ischemic properties of verapamil in the isolated rat heart.

    abstract::Using an isolated rat heart preparation under both aerobic and ischemic conditions we have characterized the temperature dependency of the slow calcium channel-blocking drug verapamil. In the first series of studies, isolated working rat hearts were subjected to global ischemia at 37 degrees, 34 degrees, 31 degrees, 2...


    pub_type: 杂志文章


    authors: Hearse DJ,Yamamoto F,Shattock MJ

    更新日期:1984-09-01 00:00:00

  • Magnesium content of serum, circulating mononuclear cells, skeletal muscle, and myocardium in congestive heart failure.

    abstract::Deranged magnesium concentrations in serum and cardiovascular structures have been implicated in the pathophysiology of hypertension, ischemic heart disease, arrhythmias, and sudden death. This study was conducted to determine the status and interrelation of serum and tissue concentrations of magnesium in patients wit...


    pub_type: 杂志文章


    authors: Ralston MA,Murnane MR,Kelley RE,Altschuld RA,Unverferth DV,Leier CV

    更新日期:1989-09-01 00:00:00

  • Improvement of endocardial and vascular endothelial function on myocardial performance by captopril treatment in postinfarct rat hearts.

    abstract::Background-Endocardial (EE) and myocardial capillary vascular endothelial (myocap VE) cells have been shown to modulate the contractile characteristics of myocardium in a calcium-dependent manner. We evaluated the endothelial-myocardial interaction in the rat postinfarction myocardial infarction (MI) model and the eff...


    pub_type: 杂志文章


    authors: Qi XL,Stewart DJ,Gosselin H,Azad A,Picard P,Andries L,Sys SU,Brutsaert DL,Rouleau JL

    更新日期:1999-09-21 00:00:00

  • Correlation between left ventricular hypertrophy and GAA trinucleotide repeat length in Friedreich's ataxia.

    abstract:BACKGROUND:Friedreich's ataxia (FA), the most common inherited ataxia, is associated frequently with cardiac hypertrophy, and death is often cardiac related. Recently, the disease has been associated with a mutation that consists of an unstable expansion of GAA repeats in the first intron of the gene encoding frataxin ...


    pub_type: 杂志文章


    authors: Isnard R,Kalotka H,Dürr A,Cossée M,Schmitt M,Pousset F,Thomas D,Brice A,Koenig M,Komajda M

    更新日期:1997-05-06 00:00:00

  • Baroreflex sensitivity, clinical correlates, and cardiovascular mortality among patients with a first myocardial infarction. A prospective study.

    abstract::Experimental studies have shown that among dogs with a healed myocardial infarction, depressed baroreflex sensitivity (BRS) identifies a subgroup at higher risk for sudden death. We have examined the relation among BRS, several clinical cardiovascular variables, and subsequent mortality in 78 patients below the age of...


    pub_type: 杂志文章


    authors: La Rovere MT,Specchia G,Mortara A,Schwartz PJ

    更新日期:1988-10-01 00:00:00

  • Abnormal systolic intraventricular flow velocities after valve replacement for aortic stenosis. Mechanisms, predictive factors, and prognostic significance.

    abstract:BACKGROUND:Dynamic intraventricular flow velocities after valve replacement for aortic stenosis have been associated with high in-hospital morbidity and mortality. The aims of the present study were to determine the mechanisms and preoperative predictors of abnormal flow velocity (AFV) after valve replacement for aorti...


    pub_type: 杂志文章


    authors: Bartunek J,Sys SU,Rodrigues AC,van Schuerbeeck E,Mortier L,de Bruyne B

    更新日期:1996-02-15 00:00:00

  • Reduction in myocardial infarct size by basic fibroblast growth factor after temporary coronary occlusion in a canine model.

    abstract:BACKGROUND:Basic fibroblast growth factor (bFGF) has been shown to reduce infarct size in canine acute myocardial infarction; however, the mechanism of tissue salvage remains uncertain. We evaluated the effect of bFGF on infarct size in a model of acute infarction in which coronary occlusion was followed by prolonged r...


    pub_type: 杂志文章


    authors: Horrigan MC,MacIsaac AI,Nicolini FA,Vince DG,Lee P,Ellis SG,Topol EJ

    更新日期:1996-10-15 00:00:00

  • Comparison of echocardiographic dyssynchrony assessment by tissue velocity and strain imaging in subjects with or without systolic dysfunction and with or without left bundle-branch block.

    abstract:BACKGROUND:Several echocardiographic dyssynchrony indexes have been proposed to identify responders to cardiac resynchronization therapy using tissue velocity and strain. The present study aimed to compare tissue velocity-derived and strain-derived dyssynchrony indexes in patients with or without systolic dysfunction a...


    pub_type: 杂志文章


    authors: Miyazaki C,Powell BD,Bruce CJ,Espinosa RE,Redfield MM,Miller FA,Hayes DL,Cha YM,Oh JK

    更新日期:2008-05-20 00:00:00

  • Indium 111-monoclonal antimyosin antibody imaging in the diagnosis of acute myocarditis.

    abstract::A definitive diagnosis of myocarditis requires right ventricular biopsy. Despite its specificity, however, right ventricular biopsy may lack sensitivity due to the focal nature of the disease. Because indium 111-monoclonal antimyosin antibody imaging can be used to detect myocardial necrosis, this procedure was perfor...


    pub_type: 杂志文章


    authors: Yasuda T,Palacios IF,Dec GW,Fallon JT,Gold HK,Leinbach RC,Strauss HW,Khaw BA,Haber E

    更新日期:1987-08-01 00:00:00

  • Diagnosis of noninfective cardiac mass lesions by two-dimensional echocardiography. Comparison of the transthoracic and transesophageal approaches.

    abstract::This study was conducted in 46 patients with cardiac thrombi, 15 patients with atrial myxomas, and 32 patients with other cardiac or paracardiac tumors. Diagnoses were subsequently proven by surgery, autopsy, computed tomography, magnetic resonance imaging, or angiography in all patients. All patients underwent precor...


    pub_type: 临床试验,杂志文章


    authors: Mügge A,Daniel WG,Haverich A,Lichtlen PR

    更新日期:1991-01-01 00:00:00

  • An oligosaccharide sialyl-Lewis(x) analogue does not reduce myocardial infarct size after ischemia and reperfusion in dogs.

    abstract:BACKGROUND:Polymorphonuclear leukocytes, particularly neutrophils, are important mediators of ischemia/reperfusion-induced myocardial and coronary vascular injury. The selectin family of glycoprotein receptors mediates neutrophil "rolling," a loose, transient adhesion to the coronary endothelium that precedes the firme...


    pub_type: 杂志文章


    authors: Gill EA,Kong Y,Horwitz LD

    更新日期:1996-08-01 00:00:00

  • The opioid system in cardiac and vascular regulation of normal and hypertensive states.

    abstract::The endogenous opioid system includes three major families of peptides: dynorphins (derived from pre-proenkephalin B), endorphins (derived from pre-proopiomelanocortin), and enkephalins (derived from pre-proenkephalin A). Multiple species of opioid peptides are derived from these major precursors and many of them poss...


    pub_type: 杂志文章,评审


    authors: Feuerstein G,Sirén AL

    更新日期:1987-01-01 00:00:00

  • Study of Cardiovascular Health Outcomes in the Era of Claims Data: The Cardiovascular Health Study.

    abstract:BACKGROUND:Increasingly, the diagnostic codes from administrative claims data are being used as clinical outcomes. METHODS AND RESULTS:Data from the Cardiovascular Health Study (CHS) were used to compare event rates and risk factor associations between adjudicated hospitalized cardiovascular events and claims-based me...


    pub_type: 杂志文章,多中心研究


    authors: Psaty BM,Delaney JA,Arnold AM,Curtis LH,Fitzpatrick AL,Heckbert SR,McKnight B,Ives D,Gottdiener JS,Kuller LH,Longstreth WT Jr

    更新日期:2016-01-12 00:00:00

  • Extensible behavior of titin in the miniswine left ventricle.

    abstract:BACKGROUND:The sarcomeric protein titin is a molecular spring responsible for passive tension and restoring forces of cardiomyocytes. Extension of titin as a function of sarcomere length (SL) has been studied in rodents, which predominantly express the smaller, stiffer N2B titin isoform. Large mammals coexpress roughly...


    pub_type: 杂志文章


    authors: Lewinter MM,Popper J,McNabb M,Nyland L,Bell SB,Granzier H

    更新日期:2010-02-16 00:00:00

  • Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques.

    abstract:BACKGROUND:Several recent studies attempted to classify plaques as those prone to cause clinical manifestations (vulnerable, atheromatous plaques) or those less frequently associated with acute thrombotic complication (stable, fibrous plaques). Defining the cellular and molecular mechanisms that underlie these morpholo...


    pub_type: 杂志文章


    authors: Sukhova GK,Schönbeck U,Rabkin E,Schoen FJ,Poole AR,Billinghurst RC,Libby P

    更新日期:1999-05-18 00:00:00

  • Unique features and prognosis of primum ASD presenting in the first year of life.

    abstract:BACKGROUND:Primum atrial septal defect (ASD) is a defect that is usually associated with few symptoms and can be electively repaired with good results. A review of our experience with primum ASD identified a subset of patients characterized by presentation with congestive heart failure (CHF) in the first months of life...


    pub_type: 杂志文章


    authors: Manning PB,Mayer JE Jr,Sanders SP,Coleman EA,Jonas RA,Keane JF,VanPraagh S,Castañeda AR

    更新日期:1994-11-01 00:00:00

  • Diurnal distribution of ST-segment elevation and related arrhythmias in patients with variant angina: a study by ambulatory ECG monitoring.

    abstract::Twenty-four-hour ambulatory ECG recording was performed in 26 patients with variant angina to evaluate the diurnal distribution of ST-segment elevation in relation to chest pain and the incidence of arrhythmias during the episodes. During a recording period of 52 days, 364 ST-segment elevations of 1 mm or greater were...


    pub_type: 杂志文章


    authors: Araki H,Koiwaya Y,Nakagaki O,Nakamura M

    更新日期:1983-05-01 00:00:00

  • Enhancement of procainamide-induced rate-dependent conduction slowing by elevated myocardial extracellular potassium concentration in vivo.

    abstract::Procainamide, a type 1A antiarrhythmic drug, blocks sodium channels and reduces the maximum rate of rise of the cardiac action potential (Vmax) in a rate-dependent fashion. In vitro, the magnitude of this rate-dependent reduction in Vmax is greater in tissue that is partially depolarized at rest than in tissue with a ...


    pub_type: 杂志文章


    authors: Cascio WE,Foster JR,Buchanan JW Jr,Johnson TA,Gettes LS

    更新日期:1987-12-01 00:00:00

  • Long-term survival and repeat coronary revascularization in dialysis patients after surgical and percutaneous coronary revascularization with drug-eluting and bare metal stents in the United States.

    abstract:BACKGROUND:Few published data describe long-term survival of dialysis patients undergoing surgical versus percutaneous coronary revascularization in the era of drug-eluting stents (DES). METHODS AND RESULTS:Using United States Renal Data System data, we identified 23 033 dialysis patients who underwent coronary revasc...


    pub_type: 杂志文章


    authors: Shroff GR,Solid CA,Herzog CA

    更新日期:2013-05-07 00:00:00

  • Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice.

    abstract:BACKGROUND:Macrophage migration inhibitory factor (MIF), a cytokine that controls cell-mediated inflammatory responses, is upregulated in atherogenesis; however, its functional contribution to lesion development has not been evaluated. METHODS AND RESULTS:We studied the role of MIF on neointima lesion formation after ...


    pub_type: 杂志文章


    authors: Schober A,Bernhagen J,Thiele M,Zeiffer U,Knarren S,Roller M,Bucala R,Weber C

    更新日期:2004-01-27 00:00:00

  • Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes.

    abstract:BACKGROUND:Monocyte chemoattractant protein-1 (MCP-1) is a chemokine responsible for the recruitment of monocytes to sites of inflammation. MCP-1 appears to play a critical role at multiple stages in atherosclerosis, including the initiation of the fatty streak, promotion of plaque instability, and remodeling after myo...


    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: de Lemos JA,Morrow DA,Sabatine MS,Murphy SA,Gibson CM,Antman EM,McCabe CH,Cannon CP,Braunwald E

    更新日期:2003-02-11 00:00:00

  • Coronary atherosclerosis. A multifactorial disease.

    abstract:BACKGROUND:Several of the theories on the pathogenesis of atherosclerosis may be integrated into a single multifactorial one. According to this theory, the most likely sequence of events involved in early atherosclerosis is vascular dysfunction and/or injury, monocyte recruitment and macrophage formation, lipid deposit...


    pub_type: 杂志文章,评审


    authors: Badimon JJ,Fuster V,Chesebro JH,Badimon L

    更新日期:1993-03-01 00:00:00

  • Ejection fraction, peak exercise oxygen consumption, cardiothoracic ratio, ventricular arrhythmias, and plasma norepinephrine as determinants of prognosis in heart failure. The V-HeFT VA Cooperative Studies Group.

    abstract:BACKGROUND:Recognition of the complex pathophysiology of heart failure and its high mortality has emphasized the need for prognostic markers that can be used in clinical assessment as well as in the design of mortality trials. Data from the Department of Veterans Affairs Cooperative Vasodilator-Heart Failure Trials (V-...


    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Cohn JN,Johnson GR,Shabetai R,Loeb H,Tristani F,Rector T,Smith R,Fletcher R

    更新日期:1993-06-01 00:00:00

  • Attenuation of exercise-induced myocardial ischemia in dogs with recruitment of coronary vasodilator reserve by nifedipine.

    abstract::There is now evidence that under resting conditions coronary vasodilator reserve exists even in the presence of myocardial ischemia. Therefore, we tested the hypothesis that a vasodilator reserve may exist during exercise so that during exercise-induced ischemia a reduction in coronary constrictor tone can be produced...


    pub_type: 杂志文章


    authors: Heusch G,Guth BD,Seitelberger R,Ross J Jr

    更新日期:1987-02-01 00:00:00

  • Pace mapping using body surface potential maps to guide catheter ablation of accessory pathways in patients with Wolff-Parkinson-White syndrome.

    abstract::BACKGROUND. A pace mapping technique using body surface potential maps (BSPMs) was developed to guide the positioning of an ablation catheter at the ventricular insertion point of accessory pathways (AP) in patients with the Wolff-Parkinson-White syndrome (WPW). METHODS AND RESULTS. The study was performed on 30 WPW p...


    pub_type: 杂志文章


    authors: Dubuc M,Nadeau R,Tremblay G,Kus T,Molin F,Savard P

    更新日期:1993-01-01 00:00:00

  • Influence of pre-PTCA strategy and initial PTCA result in patients with multivessel disease: the Bypass Angioplasty Revascularization Investigation (BARI).

    abstract:BACKGROUND:In PTCA patients with multivessel coronary artery disease, incomplete revascularization (IR) is the result of both pre-PTCA strategy and initial lesion outcome. The unique contribution of these components on long-term patient outcome is uncertain. METHODS AND RESULTS:From the Bypass Angioplasty Revasculariz...


    pub_type: 杂志文章


    authors: Kip KE,Bourassa MG,Jacobs AK,Schwartz L,Feit F,Alderman EL,Weiner BH,Weiss MB,Kellett MA Jr,Sharaf BL,Dimas AP,Jones RH,Sopko G,Detre KM

    更新日期:1999-08-31 00:00:00

  • Syncope while driving: clinical characteristics, causes, and prognosis.

    abstract:BACKGROUND:The risk of syncope occurring while driving has obvious implications for personal and public safety. We aimed to define the clinical characteristics, causes, and prognosis of syncope while driving. METHODS AND RESULTS:In this case-control study of consecutive patients evaluated for syncope from 1996 through...


    pub_type: 杂志文章


    authors: Sorajja D,Nesbitt GC,Hodge DO,Low PA,Hammill SC,Gersh BJ,Shen WK

    更新日期:2009-09-15 00:00:00

  • Tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human dilated cardiomyopathy.

    abstract:BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). TNF-alpha-converting enzyme (TACE) has recently been purified and its complementary DNA cloned. The expression of TACE results in the production of a functional enzyme that has precursor TNF-alpha...


    pub_type: 杂志文章


    authors: Satoh M,Nakamura M,Saitoh H,Satoh H,Maesawa C,Segawa I,Tashiro A,Hiramori K

    更新日期:1999-06-29 00:00:00

  • Endogenous cell seeding. Remnant endothelium after stenting enhances vascular repair.

    abstract:BACKGROUND:Endothelial integrity is essential for maintaining vascular homeostasis, and endothelial denudation results in neointimal thickening. Balloon-expandable endovascular stents provide a luminal scaffolding within atherosclerotic arteries with minimal direct contact between balloon and endothelium. We wondered w...


    pub_type: 杂志文章


    authors: Rogers C,Parikh S,Seifert P,Edelman ER

    更新日期:1996-12-01 00:00:00