Abstract:
:The effect of stenosis of the left main and proximal anterior descending coronary arteries on anterior left ventricular wall dynamics was investigated in 70 patients with ischemic heart disease by the use of roentgen videometric analysis of left ventricular angiograms. In all patients with ischemic heart disease, mean values for peak rate of systolic wall thickening and diastolic wall thinning were significantly smaller than normal (P less than 0.01). In patients without infarction, there was no correlation between peak rate of systolic anterior wall thickening and stenosis of the coronary artery supplying it, but there was a significant reduction in peak rate of diastolic wall thinning (P less than 0.01) in patients with stenosis greater than 90%; this difference was not apparent at any lower degree of stenosis. This population could not be recognized by any other parameter of global or regional ventricular function; thus, diastole is more sensitive to regional left ventricular dysfunction than systole.
journal_name
Circulationjournal_title
Circulationauthors
St John Sutton MG,Frye RL,Smith HC,Chesebro JH,Ritman ELdoi
10.1161/01.cir.58.3.491subject
Has Abstractpub_date
1978-09-01 00:00:00pages
491-7issue
3 Pt 1eissn
0009-7322issn
1524-4539journal_volume
58pub_type
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