Lack of association between the MEF2A gene and myocardial infarction.

abstract：BACKGROUND:Despite successful surgical correction, morbidity of patients with coarctation of the aorta is increased. It is well known that these patients have impaired elastic properties of the prestenotic arteries. To find out whether these abnormalities are primarily present or develop later, we studied 17 newborns b...

journal_title：Circulation

authors： Vogt M,Kühn A,Baumgartner D,Baumgartner C,Busch R,Kostolny M,Hess J

更新日期：2005-06-21 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that several subsets of regulatory T cells that actively mediate immunologic tolerance play crucial roles in atherogenesis. Recently, orally administered anti-CD3 monoclonal antibody has been shown as an inducer of novel regulatory T cells expressing latency-associated peptide ...

journal_title：Circulation

authors： Sasaki N,Yamashita T,Takeda M,Shinohara M,Nakajima K,Tawa H,Usui T,Hirata K

更新日期：2009-11-17 00:00:00

abstract：BACKGROUND:From 1958 to 1969, 592 patients (mostly children) with pulmonary stenosis were admitted to the First Natural History Study of Congenital Heart Defects (NHS-1) after cardiac catheterization. Most with gradients < 50 mm Hg were managed medically; most with gradients > or = 80 mm Hg had pulmonary valvotomy. Amo...

journal_title：Circulation

authors： Hayes CJ,Gersony WM,Driscoll DJ,Keane JF,Kidd L,O'Fallon WM,Pieroni DR,Wolfe RR,Weidman WH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:During the initial phase of an ischemic insult, left ventricular (LV) performance depends on the complex interaction between oxygen deprivation, vascular turgor, and accumulation of metabolites. In experimental preparations, low-flow ischemia decreases systolic shortening and increases diastolic LV distensib...

journal_title：Circulation

authors： De Bruyne B,Bronzwaer JG,Heyndrickx GR,Paulus WJ

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:The associations between pregnancy hypertensive disorders and common cardiovascular disorders have not been investigated at scale in a contemporaneous population. We aimed to investigate the association between preeclampsia, hypertensive disorders of pregnancy, and subsequent diagnosis of 12 different cardio...

journal_title：Circulation

authors： Leon LJ,McCarthy FP,Direk K,Gonzalez-Izquierdo A,Prieto-Merino D,Casas JP,Chappell L

更新日期：2019-09-24 00:00:00

abstract：BACKGROUND:Aging is associated with increased cardiovascular risk and endothelial dysfunction. Since exercise can improve endothelium-dependent vasodilation, in the present study we tested whether long-term physical activity could prevent aging-related endothelial dysfunction. METHODS AND RESULTS:In 12 young and elder...

journal_title：Circulation

authors： Taddei S,Galetta F,Virdis A,Ghiadoni L,Salvetti G,Franzoni F,Giusti C,Salvetti A

更新日期：2000-06-27 00:00:00

abstract：BACKGROUND:Hemodynamic efficiency of Fontan circulation is believed to be a major determinant of outcome. Prior research on flow dynamics in different modifications of Fontan circulation used in vitro models and computer-based simulation. This study was designed to compare in vivo flow dynamics in the systemic venous p...

journal_title：Circulation

authors： Be'eri E,Maier SE,Landzberg MJ,Chung T,Geva T

更新日期：1998-12-22 00:00:00

abstract：BACKGROUND:Coconut oil is high in saturated fat and may, therefore, raise serum cholesterol concentrations, but beneficial effects on other cardiovascular risk factors have also been suggested. Therefore, we conducted a systematic review of the effect of coconut oil consumption on blood lipids and other cardiovascular ...

journal_title：Circulation

authors： Neelakantan N,Seah JYH,van Dam RM

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:Recent advances in surgical techniques for the repair of left ventricular aneurysms (LVAs) include the use of an endoventricular patch to exclude the aneurysm cavity. This technique has replaced conventional linear plication of the aneurysm. The endoventricular patch technique remodels the left ventricular c...

journal_title：Circulation

authors： Grossi EA,Chinitz LA,Galloway AC,Delianides J,Schwartz DS,McLoughlin DE,Keller N,Kronzon I,Spencer FC,Colvin SB

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:A line of block in the right atrium (RA) between the venae cavae is necessary to obtain classic atrial flutter (AFL). We tested the hypothesis that the location of that line of block would determine whether the AFL reentrant circuit would be due to single-loop reentry or figure-of-8 reentry. METHODS AND RES...

journal_title：Circulation

authors： Tomita Y,Matsuo K,Sahadevan J,Khrestian CM,Waldo AL

更新日期：2001-02-20 00:00:00

abstract：BACKGROUND:The aim of this study was to prospectively test whether the risk of bleeding complications in 212 consecutive outpatients treated with oral anticoagulants could be predicted by levels of endothelium-derived hemostatic variables. METHODS AND RESULTS:All bleeding complications were recorded during 5 years of ...

journal_title：Circulation

authors： Jansson JH,Boman K,Brännström M,Nilsson TK

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Differences in vascular reactivity to phenylephrine (PE) responsiveness have been largely evidenced in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Because nitric oxide (NO) strongly affects modulation of the vascular tone in response to vasopressor agents, we hypothesized that the ...

journal_title：Circulation

authors： Philip I,Plantefeve G,Vuillaumier-Barrot S,Vicaut E,LeMarie C,Henrion D,Poirier O,Levy BI,Desmonts JM,Durand G,Benessiano J

更新日期：1999-06-22 00:00:00

abstract：BACKGROUND:Titin is a giant elastic protein that spans the half-sarcomere from Z-disk to M-band. It acts as a molecular spring and mechanosensor and has been linked to striated muscle disease. The pathways that govern titin-dependent cardiac growth and contribute to disease are diverse and difficult to dissect. METHOD...

journal_title：Circulation

authors： Radke MH,Polack C,Methawasin M,Fink C,Granzier HL,Gotthardt M

更新日期：2019-04-09 00:00:00

abstract：BACKGROUND:The purposes of this study were to evaluate the comparative accuracy of dobutamine echocardiography and quantitative rest-redistribution 201Tl tomography in the prediction of recovery of function after revascularization and to assess the relation of contractile reserve to thallium uptake. METHODS AND RESULT...

journal_title：Circulation

authors： Qureshi U,Nagueh SF,Afridi I,Vaduganathan P,Blaustein A,Verani MS,Winters WL Jr,Zoghbi WA

更新日期：1997-02-04 00:00:00

abstract：BACKGROUND:Venous coronary artery bypass grafts (CABGs) are prone to accelerated atherosclerosis. In atherosclerotic diseases, serum C-reactive protein (CRP) levels have become an important diagnostic and prognostic marker. The origin of CRP in this setting remains to be elucidated. METHODS AND RESULTS:Monoclonal anti...

journal_title：Circulation

authors： Jabs WJ,Theissing E,Nitschke M,Bechtel JF,Duchrow M,Mohamed S,Jahrbeck B,Sievers HH,Steinhoff J,Bartels C

更新日期：2003-09-23 00:00:00

abstract：:Of 1,801 patients in the 1985-1986 Percutaneous Transluminal Coronary Angioplasty (PTCA) Registry, 122 (6.8%) had periprocedural occlusion (4.9% in the catheterization laboratory, 1.9% outside the laboratory). Baseline patient factors independently associated with increased occlusion rates included triple-vessel disea...

journal_title：Circulation

authors： Detre KM,Holmes DR Jr,Holubkov R,Cowley MJ,Bourassa MG,Faxon DP,Dorros GR,Bentivoglio LG,Kent KM,Myler RK

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:In patients with atrial fibrillation (AF), the risk of thromboembolic events (TEs) is variable and is influenced by the presence and number of comorbid conditions. The effect of percutaneous left atrial radiofrequency ablation (LARFA) of AF on the risk of TEs is unclear. METHODS AND RESULTS:LARFA was perfor...

journal_title：Circulation

authors： Oral H,Chugh A,Ozaydin M,Good E,Fortino J,Sankaran S,Reich S,Igic P,Elmouchi D,Tschopp D,Wimmer A,Dey S,Crawford T,Pelosi F Jr,Jongnarangsin K,Bogun F,Morady F

更新日期：2006-08-22 00:00:00

abstract：BACKGROUND:The pulmonary circulation is an important site for the production and clearance of endothelin (ET)-1, a potent vasoactive and mitogenic peptide. Increased plasma ET-1 levels are observed in pulmonary arterial hypertension (PHT) and may contribute to the regulation of pulmonary vascular resistance, as well as...

journal_title：Circulation

authors： Bauer M,Wilkens H,Langer F,Schneider SO,Lausberg H,Schäfers HJ

更新日期：2002-03-05 00:00:00

abstract：BACKGROUND:Patients with bicuspid aortic valve (AV) stenosis were excluded from the pivotal evaluations of transcatheter AV replacement (TAVR) devices. We sought to evaluate the outcomes of TAVR in patients with bicuspid AV stenosis in comparison with those with tricuspid AV stenosis. METHODS:We used data from the Soc...

journal_title：Circulation

authors： Halim SA,Edwards FH,Dai D,Li Z,Mack MJ,Holmes DR,Tuzcu EM,Thourani VH,Harrison JK,Brennan JM

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:The relation between left ventricular (LV) oxygen consumption (MVO2) and pressure-volume area (PVA) developed in isolated hearts provides a powerful method to understand cardiac energetics. We investigated application of this relation to the intact circulation, determining its response to steady-state and tr...

journal_title：Circulation

authors： Nozawa T,Cheng CP,Noda T,Little WC

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:National and international guidelines recommend fasting lipid panel measurement for risk stratification of patients for prevention of cardiovascular events. However, the prognostic value of fasting versus nonfasting low-density lipoprotein cholesterol (LDL-C) is uncertain. METHODS AND RESULTS:Patients enrol...

journal_title：Circulation

authors： Doran B,Guo Y,Xu J,Weintraub H,Mora S,Maron DJ,Bangalore S

更新日期：2014-08-12 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair offers a less invasive approach for the treatment of ruptured descending thoracic aortic aneurysms (rDTAA). Due to the low incidence of this life-threatening condition, little is known about the outcomes of endovascular repair of rDTAA and the factors that affect these out...

journal_title：Circulation

authors： Jonker FH,Verhagen HJ,Lin PH,Heijmen RH,Trimarchi S,Lee WA,Moll FL,Athamneh H,Muhs BE

更新日期：2010-06-29 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP) plasma levels have been associated with short- and long-term occurrence of coronary events. We investigated whether circulating inflammatory cell responsiveness to low-grade stimuli could contribute to the reported association between CRP and coronary events. METHODS AND RESULTS:We ...

journal_title：Circulation

authors： Liuzzo G,Angiolillo DJ,Buffon A,Rizzello V,Colizzi C,Ginnetti F,Biasucci LM,Maseri A

更新日期：2001-05-08 00:00:00

abstract：BACKGROUND:The majority of infrarenal abdominal aortic aneurysm (AAA) repairs in the United States are performed with endovascular methods. Baseline aortoiliac arterial anatomic characteristics are fundamental criteria for appropriate patient selection for endovascular aortic repair (EVAR) and key determinants of long-...

journal_title：Circulation

authors： Schanzer A,Greenberg RK,Hevelone N,Robinson WP,Eslami MH,Goldberg RJ,Messina L

更新日期：2011-06-21 00:00:00

abstract：BACKGROUND:We sought to define the factors associated with the occurrence of stroke and systemic embolism in a large, international atrial fibrillation (AF) trial. METHODS AND RESULTS:In ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and...

journal_title：Circulation

authors： Piccini JP,Stevens SR,Chang Y,Singer DE,Lokhnygina Y,Go AS,Patel MR,Mahaffey KW,Halperin JL,Breithardt G,Hankey GJ,Hacke W,Becker RC,Nessel CC,Fox KA,Califf RM,ROCKET AF Steering Committee and Investigators.

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:Vasodilator drugs have variable effects on veins and arteries. However, direct measurements of their effects on the splanchnic veins, perhaps the most important volume reservoir, have not been reported. We assessed the effect of acute heart failure and the subsequent administration of hydralazine, enalaprila...

journal_title：Circulation

authors： Wang SY,Manyari DE,Scott-Douglas N,Smiseth OA,Smith ER,Tyberg JV

更新日期：1995-02-15 00:00:00

abstract：:Mitochondria have emerged as a central factor in the pathogenesis and progression of heart failure, and other cardiovascular diseases, as well, but no therapies are available to treat mitochondrial dysfunction. The National Heart, Lung, and Blood Institute convened a group of leading experts in heart failure, cardiova...

journal_title：Circulation

authors： Tian R,Colucci WS,Arany Z,Bachschmid MM,Ballinger SW,Boudina S,Bruce JE,Busija DW,Dikalov S,Dorn GW II,Galis ZS,Gottlieb RA,Kelly DP,Kitsis RN,Kohr MJ,Levy D,Lewandowski ED,McClung JM,Mochly-Rosen D,O'Brien KD,O'R

更新日期：2019-10-01 00:00:00

abstract：:The ameliorative effect of antiplatelet therapy on atherogenesis of vein grafts was assessed in autologous cephalic veins grafted into femoral arteries of 16 normolipemic and 11 hyperlipemic stump-tailed macaque monkeys. Before grafting, one half of each vein was distended at high pressure (700 mm Hg) and the other ha...

journal_title：Circulation

authors： Bonchek LI,Boerboom LE,Olinger GN,Pepper JR,Munns J,Hutchinson L,Kissebah AH

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:The fatty acid composition of the phospholipids in sarcolemma may significantly influence cell membrane functions. We evaluated the effects of dietary fat on the pharmacodynamics of the antiarrhythmic drug propafenone in isolated, perfused rabbit hearts. METHODS AND RESULTS:Three groups of weanling rabbits ...

journal_title：Circulation

authors： Gillis AM,Keashly R,Watson PA,Mathison HJ,Parsons HG

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Identification of genes that are specifically activated in restenosis lesions after percutaneous transluminal angioplasty represents a necessary step toward molecular manipulation designed to inhibit cellular proliferation responsible for such lesions. Whereas quiescent smooth muscle cells (contractile pheno...

journal_title：Circulation

authors： Leclerc G,Isner JM,Kearney M,Simons M,Safian RD,Baim DS,Weir L

更新日期：1992-02-01 00:00:00