Is autoimmune thyroiditis a risk factor for early atherosclerosis in premenopausal women even if in euthyroid status?

abstract：PURPOSE:In previous studies, associations between breast-milk cortisol levels obtained on one occasion and infant neurodevelopment were demonstrated. However, more recent evidence indicates that breast-milk cortisol and cortisone concentrations follow the diurnal rhythm of maternal hypothalamus-pituitary-adrenal axis, ...

journal_title：Endocrine

authors： Toorop AA,van der Voorn B,Hollanders JJ,Dijkstra LR,Dolman KM,Heijboer AC,Rotteveel J,Honig A,Finken MJJ

更新日期：2020-06-01 00:00:00

abstract：:Interactions between testosterone, estradiol, and inhibin in the control of gonadotrophin secretion in males are poorly understood. Castrated rams were treated with steroid-free bovine follicular fluid (bFF), testosterone, or estradiol and for 7 d (2 x 2 x 2 factorial design). Given independently, none of the exogenou...

journal_title：Endocrine

authors： Blache D,Tjondronegoro S,Blackberry MA,Anderson ST,Curlewis JD,Martin GB

更新日期：1997-10-01 00:00:00

abstract：PURPOSE:Levothyroxine supplementation is insufficient for the management of one tenth of patients with hypothyroidism. Iodothyronine deiodinases have been suggested to play a role in residual hypothyroid symptoms of these patients by controlling local thyroid hormone homeostasis. Previous research has suggested a relat...

journal_title：Endocrine

authors： Young Cho Y,Jeong Kim H,Won Jang H,Hyuk Kim T,Ki CS,Wook Kim S,Hoon Chung J

更新日期：2017-07-01 00:00:00

abstract：:Mammalian reproduction is dependent on both a successful pregnancy and on the subsequent period of lactation. In the rat, ovulation occurs shortly after parturition making it possible for a dam to be simultaneously pregnant and lactating. The present studies investigate the effect of placental hormones on suckling-ind...

journal_title：Endocrine

authors： Flietstra RJ,Voogt JL

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Rathke's cleft cysts (RCC) are lesions that arise from Rathke's pouch. Though frequently incidental, resulting symptoms in a minority of cases are indicators for surgical resection, which may prove beneficial. OBJECTIVE:To characterize a cohort of surgically-resected RCC cases at Oregon Health & Science Uni...

journal_title：Endocrine

authors： Langlois F,Manea A,Lim DST,McCartney S,Yedinak CG,Cetas JS,Fleseriu M

更新日期：2019-03-01 00:00:00

abstract：:To explore the regulation of follistatin gene expression, porcine granulosa cells were incubated with the translational inhibitor, cycloheximide (CHX), for periods from 6-24 h. This resulted in a 3 to 10-fold increase in follistatin mRNA accumulation compared to vehicle treated control cultures. At 20 h, CHX augmented...

journal_title：Endocrine

authors： Lindsell CE,Misra V,Murphy BD

更新日期：1995-08-01 00:00:00

abstract：:Bilirubin concentrations have been recently reported to be negatively associated with type 2 diabetes mellitus. We examined the association between bilirubin concentrations and gestational diabetes mellitus. In a prospective cohort study, 2969 pregnant women were recruited prior to 16 weeks of gestation and were follo...

journal_title：Endocrine

authors： Liu C,Zhong C,Zhou X,Chen R,Wu J,Wang W,Li X,Ding H,Guo Y,Gao Q,Hu X,Xiong G,Yang X,Hao L,Xiao M,Yang N

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Diabetes mellitus (DM) has a multifactorial etiology that imparts a particular challenge to effective pharmacotherapy. Thyroid hormone actions have demonstrated beneficial effects in diabetic as well as obese rats. In both conditions, inflammation status plays a crucial role in the development of insulin resist...

journal_title：Endocrine

authors： Panveloski-Costa AC,Kuwabara WMT,Munhoz AC,Lucena CF,Curi R,Carpinelli AR,Nunes MT

更新日期：2020-05-01 00:00:00

abstract：:Administration of RU486 to late pregnant rats results in preterm delivery 24 h after treatment and the induction of a luteolytic process after labor. We investigated whether functional changes occurring within the corpora lutea after RU486 treatment were associated with morphologic features of apoptotic cell death. Ra...

journal_title：Endocrine

authors： Telleria CM,Goyeneche AA,Cavicchia JC,Stati AO,Deis RP

更新日期：2001-07-01 00:00:00

abstract：:The present study investigates the effects of functional sensorial denervation, induced by administering capsaicin to hemiovariectomized adult female rats in each day of the estrus cycle, on ovulation and serum concentrations of estrogen and progesterone. The results indicate that the establishment of compensatory ova...

journal_title：Endocrine

authors： Trujillo A,Morales L,Vargas X,Alba L,Domínguez R

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To evaluate whether losartan is able to induce beige adipocytes formation, focusing on the thermogenic gene expression and adipocyte remodeling in the subcutaneous white adipose tissue of diet-induced obese mice. METHODS:Male C57BL/6 mice received a control diet (10% energy as lipids) or a high-fat diet (50% e...

journal_title：Endocrine

authors： Graus-Nunes F,Rachid TL,de Oliveira Santos F,Barbosa-da-Silva S,Souza-Mello V

更新日期：2017-03-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a rare disease in which the most common endocrine manifestation is diabetes insipidus (DI). Data on anterior pituitary function in patients with LCH are limited. Thus, the present study investigated anterior pituitary function in LCH patients with DI via the evaluation of clinica...

journal_title：Endocrine

authors： Kurtulmus N,Mert M,Tanakol R,Yarman S

更新日期：2015-04-01 00:00:00

abstract：:External ATP is believed to initiate and propagate Ca(2+) signals co-ordinating the insulin release pulses within and among the different islets in the pancreas. The possibility that islet endothelial cells participate in this process was evaluated by comparing the effects on [Ca(2+)](i) of purinoceptor activation in ...

journal_title：Endocrine

authors： Hellman B,Jansson L,Dansk H,Grapengiesser E

更新日期：2007-08-01 00:00:00

abstract：:Children born large for gestational age (LGA) may be at risk for development of obesity and insulin resistance (IR). The reciprocal relationship of adipokines and proinflammatory cytokines is suggested to play a putative role in fine tuning of insulin secretory dynamics. To evaluate serum interleukin-6 (IL-6), tumor n...

journal_title：Endocrine

authors： Cetin C,Baş F,Uçar A,Poyrazoğlu S,Saka N,Bundak R,Darendeliler F

更新日期：2014-12-01 00:00:00

abstract：:Estrogens increase prolactin (PRL) synthesis and release in rats and humans, whereas pituitary-derived calcitonin-like immunoreactive peptide (pit-CT) inhibits PRL gene expression and release. To test the hypothesis that estrogens stimulate lactotrophs by diminishing pit-CT expression, the present studies examined eff...

journal_title：Endocrine

authors： Li Z,Shah GV

更新日期：1995-06-01 00:00:00

abstract：:Graves' disease (GD) and Hashimoto's thyroiditis (HT) are both common autoimmune diseases of the thyroid gland (AITD). The IL-4 is involved in both humoral and cellular immunity. The aim of this study was to test whether the IL-4 gene could be used as a genetic marker to predict the development of AITD amongst the Chi...

journal_title：Endocrine

authors： Chen RH,Chang CT,Wang TY,Chen CC,Tsai CH,Tsai FJ

更新日期：2007-10-01 00:00:00

abstract：:Ghrelin is an endogenous growth hormone secretagogue (GHS) causing release of GH from pituitary somatotropes through the GHS receptor. Secretion of GH is linked directly to intracellular free Ca2+ concentration ([Ca2+]i), which is determined by Ca2+ influx and release from intracellular Ca2+ storage sites. Ca2+ influx...

journal_title：Endocrine

authors： Han X,Zhu Y,Zhao Y,Chen C

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:In the general population, sleep disorders are associated with an increased risk of cognitive impairment. The prevalence of sleep disorders, such as sleep apnea, in acromegalic patients is higher than in the general population, and they may have additional risk of cognitive impairment due to acromegaly treatmen...

journal_title：Endocrine

authors： Wennberg A,Lorusso R,Dassie F,Benavides-Varela S,Parolin M,De Carlo E,Fallo F,Mioni R,Vettor R,Semenza C,Maffei P

更新日期：2019-12-01 00:00:00

abstract：:Fifty children ages 4-10 yr with type 1 diabetes mellitus volunteered to participate in a study to evaluate and compare a new needle-free device developed for growth hormone delivery. Children answered descriptive questions related to nervousness and worry, hurt or pain, redness or bleeding, and stinging and wetness. ...

journal_title：Endocrine

authors： Silverstein JH,Murray FT,Malasanos T,Myers S,Johnson SB,Frye K,Grossman M

更新日期：2001-06-01 00:00:00

abstract：:Recent animal studies support close associations of Periostin with hepatosteatosis and steatohepatitis. This study is to evaluate the role of serum periostin in non-alcoholic fatty liver disease (NAFLD). A hospital-based age-/sex-matched case-control study was conducted. Binary logistic regression and receiver operati...

journal_title：Endocrine

authors： Zhu JZ,Zhu HT,Dai YN,Li CX,Fang ZY,Zhao DJ,Wan XY,Wang YM,Wang F,Yu CH,Li YM

更新日期：2016-01-01 00:00:00

abstract：:The handgrip strength is considered an excellent predictor of morbidity and mortality for acute and long term outcomes. In fact, several studies showed that the reduced handgrip strength is correlated to all-cause mortality in both middle aged and elderly subjects. Nevertheless, defined reference values of handgrip st...

journal_title：Endocrine

authors： Montalcini T,Migliaccio V,Yvelise F,Rotundo S,Mazza E,Liberato A,Pujia A

更新日期：2013-04-01 00:00:00

abstract：:Alendronate is a well-established treatment for osteoporosis and suppresses bone resorption by a direct effect on osteoclasts and their precursors. The effect of alendronate on osteoclasts is produced, at least in part, by the receptor activator of nuclear factor kappaB ligand (RANKL) and the osteoprotegerin (OPG) syn...

journal_title：Endocrine

authors： Enjuanes A,Ruiz-Gaspà S,Peris P,Ozalla D,Alvarez L,Combalia A,Martínez de Osaba MJ,Monegal A,Pares A,Guañabens N

更新日期：2010-04-01 00:00:00

abstract：:Riedel's thyroiditis (RT) is a rare type of chronic thyroiditis of unproven etiology and definite treatment. It can be associated with retroperitoneal, mediastinal, orbital, and hepatic fibrosis. Symptoms arise mainly due to compression of neighboring structures. Surgery is usually required for a definite diagnosis an...

journal_title：Endocrine

authors： Erdoğan MF,Anil C,Türkçapar N,Ozkaramanli D,Sak SD,Erdoğan G

更新日期：2009-06-01 00:00:00

abstract：PURPOSE:We aimed to evaluate the performance of structural magnetic resonance imaging (MRI)-based quantitative measurements at extraocular muscle (EOM), orbital fat (OF), and especially lacrimal gland (LG) in predicting response to glucocorticoid (GC) in patients with active and moderate-severe thyroid-associated ophth...

journal_title：Endocrine

authors： Hu H,Xu XQ,Chen L,Chen W,Wu Q,Chen HH,Zhu H,Shi HB,Wu FY

更新日期：2020-11-01 00:00:00

abstract：:A mechanism explaining the differential skeletal effects of intermittent and continuous elevation of serum parathyroid hormone (PTH) remains elusive. Intermittent PTH increases bone formation and bone mass and is being investigated as a therapy for osteoporosis. By contrast, chronic hyperparathyroidism results in the ...

journal_title：Endocrine

authors： Lotinun S,Sibonga JD,Turner RT

更新日期：2002-02-01 00:00:00

abstract：PURPOSE:Parathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited number of samples. The aim of the present study was to verify a group of mi...

journal_title：Endocrine

authors： Hu Y,Zhang X,Cui M,Su Z,Wang M,Liao Q,Zhao Y

更新日期：2018-05-01 00:00:00

abstract：:Several studies have examined an association of anti-mullerian hormone to various risk factors for mortality, however, to the best of our knowledge, no study has reported a direct relationship between anti-mullerian hormone and all-cause mortality. Therefore, we examined the relationship between baseline anti-mulleria...

journal_title：Endocrine

authors： Qayyum R,Akbar S

更新日期：2016-10-01 00:00:00

abstract：:Many new techniques are rapidly being developed and applied to the study of normal and neoplastic pituitary. DNA microarrays are a uniquely efficient method for simultaneously assessing the expression levels of thousands of genes, identifying disease subphenotypes, and predicting disease progression. This article revi...

journal_title：Endocrine

authors： Qian X,Scheithauer BW,Kovacs K,Lloyd RV

更新日期：2005-10-01 00:00:00

abstract：:Leptin, the satiety hormone, has been found to affect growth-plate cartilage development. In the present study, some of the signal transduction pathways that mediate leptin signaling in the ATDC5 chondrogenic cell-line, a model for endochondral ossification, were analyzed. For this purpose, real-time PCR, Western blot...

journal_title：Endocrine

authors： Ben-Eliezer M,Phillip M,Gat-Yablonski G

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Changes in body composition are commonly present in chronic obstructive pulmonary disease (COPD). The main aim of this study were to evaluate changes in body composition and the prevalence of pre-sarcopenia and sarcopenia in patients with COPD, compared with two control groups and correlate these parameters wit...

journal_title：Endocrine

authors： Munhoz da Rocha Lemos Costa T,Costa FM,Jonasson TH,Moreira CA,Boguszewski CL,Borba VZC

更新日期：2018-04-01 00:00:00