DNA microarrays: recent developments and applications to the study of pituitary tissues.


:Many new techniques are rapidly being developed and applied to the study of normal and neoplastic pituitary. DNA microarrays are a uniquely efficient method for simultaneously assessing the expression levels of thousands of genes, identifying disease subphenotypes, and predicting disease progression. This article reviews the utility of DNA microarray-based tumor profiling including recent developments and applications to pituitary biology in order to demonstrate how these new techniques are providing insights about basic aspects, clinical knowledge, and pharmacologic knowledge of the pituitary gland and about pituitary tumors.






Qian X,Scheithauer BW,Kovacs K,Lloyd RV




Has Abstract


2005-10-01 00:00:00














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    abstract::The effects of endomorphin-1 (EM1) on behavioral responses and on the hypothalamic-pituitary-adrenal system were investigated in mice. Locomotor activity was measured in an "open-field" apparatus, with parallel recording of the numbers of rearings and groomings. Different doses of the peptide (250 ng to 5 microg) were...


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    authors: Bujdosó E,Jászberényi M,Tömböly C,Tóth G,Telegdy G

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  • In vitro and in vivo inhibition of mTOR by 1,25-dihydroxyvitamin D3 to improve early diabetic nephropathy via the DDIT4/TSC2/mTOR pathway.

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    authors: Wang H,Wang J,Qu H,Wei H,Ji B,Yang Z,Wu J,He Q,Luo Y,Liu D,Duan Y,Liu F,Deng H

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  • Effectiveness of myoinositol for polycystic ovary syndrome: a systematic review and meta-analysis.

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    pub_type: 杂志文章,meta分析,评审


    authors: Zeng L,Yang K

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  • Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression.

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    pub_type: 杂志文章


    authors: Imai M,Ishikawa K,Matsukawa N,Kida I,Ohta J,Ikushima M,Chihara Y,Rui X,Rakugi H,Ogihara T

    更新日期:2004-12-01 00:00:00

  • Control of prolactin secretion by excitatory amino acids.

    abstract::This article provides an overview of the increasing number of observations indicating that excitatory amino acids are involved in the control of prolactin secretion. The information available suggests that these amino acids exert a stimulatory action on hypophysial prolactin. Administration of a glutamate receptor ago...


    pub_type: 杂志文章,评审


    authors: Nagy GM,Bodnár I,Bánky Z,Halász B

    更新日期:2005-12-01 00:00:00

  • Treatment of multiresistant prolactinomas with a combination of cabergoline and octreotide LAR.

    abstract:BACKGROUND AND OBJECTIVES:Dopamine agonist (DA)-resistant prolactinomas are rare but they constitute a real challenge, since there are few therapeutic alternatives left for these patients. DESIGN AND SETTING:Proof-of-concept study at a tertiary care, referral center. PATIENTS AND METHODS:The studied population consis...


    pub_type: 临床试验,杂志文章


    authors: Sosa-Eroza E,Espinosa E,Ramírez-Rentería C,Mendoza V,Arreola R,Mercado M

    更新日期:2018-08-01 00:00:00

  • Hypothalamic-autonomic control of energy homeostasis.

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  • Androgen receptor expression in the testes and epididymides of prenatal and postnatal Sprague-Dawley rats.

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    authors: You L,Sar M

    更新日期:1998-12-01 00:00:00

  • Sex differences in COVID-19: the role of androgens in disease severity and progression.

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    pub_type: 杂志文章,评审


    authors: Mohamed MS,Moulin TC,Schiöth HB

    更新日期:2021-01-01 00:00:00

  • Evidence of a stabilizing mutation of β-catenin encoded by CTNNB1 exon 3 in a large series of sporadic parathyroid adenomas.

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    authors: Starker LF,Fonseca AL,Akerström G,Björklund P,Westin G,Carling T

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    authors: Rodrigo R,Rivera G,Lucero Y,Larraguibel C

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  • Pituitary-adrenal axis and peripheral cortisol metabolism in obese patients.

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    authors: Kulkarni-Paranjape T,Shah GV

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    authors: Ulivieri FM,Silva BC,Sardanelli F,Hans D,Bilezikian JP,Caudarella R

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    authors: Mertani HC,Testart C,Ouhtit A,Brisson C,Morel G

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  • Association of cord blood des-acyl ghrelin with birth weight, and placental GHS-R1 receptor expression in SGA, AGA, and LGA newborns.

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    authors: González-Domínguez MI,Lazo-de-la-Vega-Monroy ML,Zaina S,Sabanero M,Daza-Benítez L,Malacara JM,Barbosa-Sabanero G

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  • Pituitary magnetic resonance imaging in Cushing's disease.

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    authors: Vitale G,Tortora F,Baldelli R,Cocchiara F,Paragliola RM,Sbardella E,Simeoli C,Caranci F,Pivonello R,Colao A,A.B.C. Group.

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  • Differential mRNA expression of alpha and beta estrogen receptor isoforms and GnRH in the left and right side of the preoptic and anterior hypothalamic area during the estrous cycle of the rat.

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    authors: Arteaga-López PR,Domínguez R,Cerbón MA,Mendoza-Rodríguez CA,Cruz ME

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    pub_type: 杂志文章,meta分析,评审


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    pub_type: 杂志文章


    authors: Hellman B,Jansson L,Dansk H,Grapengiesser E

    更新日期:2007-08-01 00:00:00

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    abstract::Ghrelin is an endogenous growth hormone secretagogue (GHS) causing release of GH from pituitary somatotropes through the GHS receptor. Secretion of GH is linked directly to intracellular free Ca2+ concentration ([Ca2+]i), which is determined by Ca2+ influx and release from intracellular Ca2+ storage sites. Ca2+ influx...


    pub_type: 杂志文章


    authors: Han X,Zhu Y,Zhao Y,Chen C

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  • Estrogen modulates expression of putative housekeeping genes in the mouse uterus.

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    pub_type: 杂志文章


    authors: Schroder AL,Pelch KE,Nagel SC

    更新日期:2009-04-01 00:00:00

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    pub_type: 杂志文章


    authors: Cancelas J,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

    更新日期:2001-08-01 00:00:00

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    pub_type: 杂志文章


    authors: Martí O,Martín M,Gavaldà A,Giralt M,Hidalgo J,Hsu BR,Kuhn RW,Armario A

    更新日期:1997-04-01 00:00:00

  • Evaluation of oxidative status in patients with hyperthyroidism.

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    pub_type: 杂志文章


    authors: Aslan M,Cosar N,Celik H,Aksoy N,Dulger AC,Begenik H,Soyoral YU,Kucukoglu ME,Selek S

    更新日期:2011-10-01 00:00:00