DNA microarrays: recent developments and applications to the study of pituitary tissues.

abstract：:The effects of endomorphin-1 (EM1) on behavioral responses and on the hypothalamic-pituitary-adrenal system were investigated in mice. Locomotor activity was measured in an "open-field" apparatus, with parallel recording of the numbers of rearings and groomings. Different doses of the peptide (250 ng to 5 microg) were...

journal_title：Endocrine

authors： Bujdosó E,Jászberényi M,Tömböly C,Tóth G,Telegdy G

更新日期：2001-03-01 00:00:00

abstract：:We investigated whether 1,25-dihydroxy-vitamin D3 (1,25(OH)2D3) could improve early diabetic nephropathy through the DNA-damage-inducible transcript 4/tuberous sclerosis 2/mammalian target of rapamycin pathway. Rat mesangial cells were cultured in media containing normal glucose or high glucose and were treated with o...

journal_title：Endocrine

authors： Wang H,Wang J,Qu H,Wei H,Ji B,Yang Z,Wu J,He Q,Luo Y,Liu D,Duan Y,Liu F,Deng H

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To assess the effectiveness and safety of myoinositol for patients with PCOS. METHODS:In this meta-analysis, data from randomized controlled trials are obtained to assess the effects of myoinositol vs. placebo or western medicine in women with PCOS. The study's registration number is CRD42017064563. The primar...

journal_title：Endocrine

authors： Zeng L,Yang K

更新日期：2018-01-01 00:00:00

abstract：:Homozygous Klotho mutant (kl-/-) mice exhibit a variety of phenotypes resembling human aging, including arteriosclerosis, infertility, skin atrophy, osteoporosis, and short life span. Calcium abnormality, one of the phenotypes in kl-/- mice, is thought to be due to the elevated gene expression of 25-hydroxyvitamin D3 ...

journal_title：Endocrine

authors： Imai M,Ishikawa K,Matsukawa N,Kida I,Ohta J,Ikushima M,Chihara Y,Rui X,Rakugi H,Ogihara T

更新日期：2004-12-01 00:00:00

abstract：:This article provides an overview of the increasing number of observations indicating that excitatory amino acids are involved in the control of prolactin secretion. The information available suggests that these amino acids exert a stimulatory action on hypophysial prolactin. Administration of a glutamate receptor ago...

journal_title：Endocrine

authors： Nagy GM,Bodnár I,Bánky Z,Halász B

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Dopamine agonist (DA)-resistant prolactinomas are rare but they constitute a real challenge, since there are few therapeutic alternatives left for these patients. DESIGN AND SETTING:Proof-of-concept study at a tertiary care, referral center. PATIENTS AND METHODS:The studied population consis...

journal_title：Endocrine

authors： Sosa-Eroza E,Espinosa E,Ramírez-Rentería C,Mendoza V,Arreola R,Mercado M

更新日期：2018-08-01 00:00:00

abstract：:Regulation of energy homeostasis is tightly controlled by the central nervous system (CNS). Several key areas such as the hypothalamus and brainstem receive and integrate signals conveying energy status from the periphery, such as leptin, thyroid hormones, and insulin, ultimately leading to modulation of food intake, ...

journal_title：Endocrine

authors： Seoane-Collazo P,Fernø J,Gonzalez F,Diéguez C,Leis R,Nogueiras R,López M

更新日期：2015-11-01 00:00:00

abstract：:The androgen receptor (AR) plays a critical role in sexual differentiation and in the virilization of the male reproductive system. A clear understanding of AR expression at the early stages of sexual development will help elucidate the sensitivity of perinatal animals to endocrine modulation by external agents, such ...

journal_title：Endocrine

authors： You L,Sar M

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:Throughout the SARS-CoV2 pandemic, multiple reports show higher percentages of hospitalization, morbidity, and mortality among men than women, indicating that men are more affected by COVID-19. The pathophysiology of this difference is yet not established, but recent studies suggest that sex hormones may influe...

journal_title：Endocrine

authors： Mohamed MS,Moulin TC,Schiöth HB

更新日期：2021-01-01 00:00:00

abstract：:Aberrant accumulation of β-catenin plays an important role in a variety of human neoplasms. This can be caused by stabilizing mutation of β-catenin (CTNNB1, exon 3) or by mutation or deregulated expression of other components of the WNT/β-catenin signaling pathway. Accumulation of non-phosphorylated active β-catenin h...

journal_title：Endocrine

authors： Starker LF,Fonseca AL,Akerström G,Björklund P,Westin G,Carling T

更新日期：2012-12-01 00:00:00

abstract：:Chronic ethanol exposure causes alterations in biologic membranes of different cell types. (Na + K) adenosine triphosphatase (ATPase), a membrane-bound enzyme inhibited by the acute presence of ethanol, increases its activity in rat kidney after chronic ethanol consumption. The aim of this investigation was to evaluat...

journal_title：Endocrine

authors： Rodrigo R,Rivera G,Lucero Y,Larraguibel C

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:Fine-needle aspiration biopsy of the thyroid is an increasingly common outpatient procedure. Patients are counseled about the indications and risks of this procedure and informed consent is obtained. We aimed to assess the extent to which patients acquired necessary knowledge during this process. METHODS:Surve...

journal_title：Endocrine

authors： Singh Ospina N,Castaneda-Guarderas A,Ward R,Brito JP,Maraka S,Zeballos Palacios C,Yost KJ,Dean DS,Montori VM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND AIM:A close relationship between adiposity and increased cortisol levels is well established in patients with endogenous hypercortisolism. Nevertheless, hypothalamic-pituitary-adrenal (HPA) axis regulation in overweight subjects is still a matter of concern. We studied free cortisol (urinary free cortiso...

journal_title：Endocrine

authors： Ceccato F,Lizzul L,Barbot M,Scaroni C

更新日期：2020-08-01 00:00:00

abstract：:We have shown that gonadotrophs synthesize and secrete immunoreactive calcitonin (CT)-like peptide, and CT is a potent inhibitor of prolactin (PRL) secretion and gene transcription. CT cDNA cloned from LssT2 cells (pit-CT cDNA) exhibits 99% homology with mouse CT cDNA sequence, but exhibits four mismatches in the codi...

journal_title：Endocrine

authors： Kulkarni-Paranjape T,Shah GV

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:Efficacy of multi-disciplinary weight management (MDM) in youth has not been compared to their routine care. OBJECTIVES:To compare body mass index z-score (zBMI) and blood test (lab) changes (Δ) in youth before and after MDM and to correlate bio-impedance analysis (BIA) and lab measurements. METHODS:We compar...

journal_title：Endocrine

authors： Majumdar I,Espino B,Bianco K,Epstein J,Mamilly L,Harmon CM

更新日期：2019-08-01 00:00:00

abstract：:Protocols for induction of hyperthyroidism in mice are highly variable and mostly involve short-term thyroid hormone (TH) treatment. In addition, little is known about a possible influence of sex on experimental TH manipulation. Here we analyzed the efficacy of intraperitoneal vs. oral levothyroxine (T4) administratio...

journal_title：Endocrine

authors： Engels K,Rakov H,Zwanziger D,Hönes GS,Rehders M,Brix K,Köhrle J,Möller LC,Führer D

更新日期：2016-10-01 00:00:00

abstract：:Altered bone micro-architecture is an important factor in accounting for fragility fractures. Until recently, it has not been possible to gain information about skeletal microstructure in a way that is clinically feasible. Bone biopsy is essentially a research tool. High-resolution peripheral Quantitative Computed Tom...

journal_title：Endocrine

authors： Ulivieri FM,Silva BC,Sardanelli F,Hans D,Bilezikian JP,Caudarella R

更新日期：2014-11-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) effects on the lactotroph function have been widely studied, but they probably result from paracrine interactions. No visual data about GnRH receptor in the pituitary are available. In order to identify the GnRH target cells in the pituitary of adult rats, the cellular distributio...

journal_title：Endocrine

authors： Mertani HC,Testart C,Ouhtit A,Brisson C,Morel G

更新日期：1996-04-01 00:00:00

abstract：:We wanted to evaluate the cutaneous synthesis of 25OHD and cholecalciferol after one whole-body exposure to ultraviolet radiation type B (UVB) in a randomized setup. Healthy volunteers were randomized to one whole-body exposure in a commercial tanning bed with UVB emission (UVB/UVA ratio 1.8-2.0%) or an identical plac...

journal_title：Endocrine

authors： Langdahl JH,Schierbeck LL,Bang UC,Jensen JE

更新日期：2012-10-01 00:00:00

abstract：:The aim of this article is to investigate the effects of Aminoguanidine and vitamin C (VitC) on type IV collagen in diabetic nephropathy rats. Diabetic nephropathy rats were induced by intraperitoneal injection of STZ. Rats were randomly divided into five groups: normal control group (n = 10), diabetes group (n = 10),...

journal_title：Endocrine

authors： Li Q,Ao X,Du Y,Li Y,Ou Y,Gong R,Sun X,Yang YX,Wen G

更新日期：2011-06-01 00:00:00

abstract：:Although ghrelin in cord blood has been associated to birth weight, its role in fetal and postnatal growth has not been elucidated. The aim of this study was to analyze total ghrelin, acyl ghrelin (AG), and des-acyl ghrelin (DAG) in cord blood of newborns with idiopathic birth weight alterations, and to evaluate prote...

journal_title：Endocrine

authors： González-Domínguez MI,Lazo-de-la-Vega-Monroy ML,Zaina S,Sabanero M,Daza-Benítez L,Malacara JM,Barbosa-Sabanero G

更新日期：2016-07-01 00:00:00

abstract：:Adrenocorticotropin-secreting pituitary tumor represents about 10 % of pituitary adenomas and at the time of diagnosis most of them are microadenomas. Transsphenoidal surgery is the first-line treatment of Cushing's disease and accurate localization of the tumor within the gland is essential for selectively removing t...

journal_title：Endocrine

authors： Vitale G,Tortora F,Baldelli R,Cocchiara F,Paragliola RM,Sbardella E,Simeoli C,Caranci F,Pivonello R,Colao A,A.B.C. Group.

更新日期：2017-03-01 00:00:00

abstract：:Asymmetric mRNA expression was found in preoptic anterior and hypothalamic anterior areas of the two estrogen receptor isoforms and the gonadotropin-releasing hormone. On the right side of these areas, estrogen receptor alpha mRNA expression reached its peak on estrus day, while on the left side the peak was reached o...

journal_title：Endocrine

authors： Arteaga-López PR,Domínguez R,Cerbón MA,Mendoza-Rodríguez CA,Cruz ME

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:Dopamine agonists (DAs) are recommended as first-line treatment for patients with hyperprolactinemia. Generally, it is accepted that patients with hyperprolactinemia do not need lifelong medication, but the optimal timing for DA withdrawal has not been determined. The aim of this systematic review and meta-anal...

journal_title：Endocrine

authors： Xia MY,Lou XH,Lin SJ,Wu ZB

更新日期：2018-01-01 00:00:00

abstract：:External ATP is believed to initiate and propagate Ca(2+) signals co-ordinating the insulin release pulses within and among the different islets in the pancreas. The possibility that islet endothelial cells participate in this process was evaluated by comparing the effects on [Ca(2+)](i) of purinoceptor activation in ...

journal_title：Endocrine

authors： Hellman B,Jansson L,Dansk H,Grapengiesser E

更新日期：2007-08-01 00:00:00

abstract：:Ghrelin is an endogenous growth hormone secretagogue (GHS) causing release of GH from pituitary somatotropes through the GHS receptor. Secretion of GH is linked directly to intracellular free Ca2+ concentration ([Ca2+]i), which is determined by Ca2+ influx and release from intracellular Ca2+ storage sites. Ca2+ influx...

journal_title：Endocrine

authors： Han X,Zhu Y,Zhao Y,Chen C

更新日期：2011-10-01 00:00:00

abstract：:Estrogens regulate gene expression and cell proliferation in target tissues. In studies of estrogen-regulated gene expression, identification of appropriate housekeeping genes (HKGs), reference genes whose expression is not altered by treatment, is difficult. The goal of this study was to define HKGs unaltered by estr...

journal_title：Endocrine

authors： Schroder AL,Pelch KE,Nagel SC

更新日期：2009-04-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) acts as a nutrient-dependent insulin-releasing agent, and its insulinotropic action is enhanced by nutrient secretagogues, such as the dimethyl ester of succinic acid (SAD). In the present study, a primed constant infusion of SAD (0.5 micromol followed by 0.25 micromol/min both per g of...

journal_title：Endocrine

authors： Cancelas J,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：2001-08-01 00:00:00

abstract：:The effect of stress on serum corticosteroid-binding globulin (CBG) was studied in adult male Sprague-Dawley rats. CBG was measured either by a homologous radioimmunoassay (RIA) or by a binding assay (BA) using 3H-corticosterone. Exposure of adult male rats to a severe stressor such as immobilization (IMO) for 1 h did...

journal_title：Endocrine

authors： Martí O,Martín M,Gavaldà A,Giralt M,Hidalgo J,Hsu BR,Kuhn RW,Armario A

更新日期：1997-04-01 00:00:00

abstract：:Data on the antioxidant levels enzyme in patients with hyperthyroidism are limited and conflicting. Therefore, the objective of this study was to evaluate the oxidative status using an automated method in patients with hyperthyroidism. Thirty-six subjects with hyperthyroidism and 30 healthy controls were enrolled in t...

journal_title：Endocrine

authors： Aslan M,Cosar N,Celik H,Aksoy N,Dulger AC,Begenik H,Soyoral YU,Kucukoglu ME,Selek S

更新日期：2011-10-01 00:00:00