Abstract：
:Frontoparietal networks (FPNs) including the regions of the posterior parietal cortex (PPC) and dorsolateral prefrontal cortex (DLPFC) have been implicated in visuospatial attention. However, the functional interactions among different regions of dorsal FPNs remain elusive. The Attention Network Test (ANT) and continuous theta burst stimulation (cTBS) were used to investigate the functional interactions in healthy subjects. During the ANT task, subjects receiving right PPC cTBS responded significantly slower in spatial cue condition, had deficits in both alerting and orienting indices compared with those receiving either the sham cTBS or left PPC cTBS. In addition, subjects receiving left-DLPFC cTBS showed significant improvements on alerting and conflict indices whereas significant deficits on the orienting index compared with those receiving the sham cTBS. Moreover, compared with subjects exposed to the sham cTBS condition, subjects exposed to cTBS to the right-DLPFC exhibited significant decreases in the efficiency of the alerting and conflict indices whereas significant increases in the orienting index. Furthermore, there were significant differences in the alerting, orienting and conflict effect indices between subjects receiving the left-DLPFC-cTBS and those receiving the right-DLPFC-cTBS. These results suggest that the right DLPFC played a pivotal role in executive control process, whereas the right PPC was associated with orienting attentional function. The current study not only supports the model of inter-hemispheric rivalry for visuospatial attention, but also indicates inter-regional competition between the different areas of the FPNs.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Xu G,Lan Y,Huang D,Chen S,Chen L,Zeng J,Pei Zdoi
10.1016/j.bbr.2012.11.015subject
Has Abstractpub_date
2013-03-01 00:00:00pages
60-8eissn
0166-4328issn
1872-7549pii
S0166-4328(12)00737-1journal_volume
240pub_type
杂志文章,随机对照试验abstract：:Cholinergic systems have been linked to cognitive processes such as attention, learning and mnemonic function. However, other neurotransmitter systems, such as the serotonergic one, which may have only minor effects on cognitive function on their own, interact with cholinergic function and their combined effects may h...
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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pub_type： 临床试验,杂志文章
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journal_title：Behavioural brain research
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