Topography-guided transepithelial photorefractive keratectomy for irregular astigmatism using a 213 nm solid-state laser.

Abstract:

PURPOSE:To explore the use of the Pulsar Z1 solid-state 213 nm photorefractive laser platform in topography-guided transepithelial photorefractive keratectomy (PRK) for irregular astigmatism. SETTING:Moorfields Eye Hospital, London, United Kingdom. DESIGN:Prospective clinical case series. METHODS:Patients with irregular astigmatism after previous refractive surgery or corneal transplantation were treated with topography-guided transepithelial PRK. Preoperatively and 1-year postoperatively, corrected distance visual acuity (CDVA) and secondary outcome measures (including manifest refraction, contrast sensitivity, haze score, index of surface variation, root-mean-square higher-order aberrations, and subjective visual change) were compared between groups. Adjunctive mitomycin-C was not used. RESULTS:Seven patients had previous refractive surgery, and 7 had previous corneal transplantation. All but 2 patients with a marked haze response had subjective gains in vision and improved CDVA. Gains in CDVA for patients with irregular astigmatism after previous refractive surgery (median 2 lines gain; range 0 to 2 lines gained) were higher than for patients with irregular astigmatism after keratoplasty (median 0 lines; range 5 lines lost to 4 lines gained). Trends in secondary outcome measures were similar, with greater variation in post-keratoplasty patients. Haze scores were higher in post-keratoplasty patients. CONCLUSIONS:213 nm topography-guided transepithelial PRK was easy to perform and well tolerated by patients with irregular astigmatism. Most patients gained CDVA; however, increased haze responses were observed in post-keratoplasty cases.

authors

Allan BD,Hassan H

doi

10.1016/j.jcrs.2012.08.056

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

97-104

issue

1

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(12)01369-7

journal_volume

39

pub_type

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