Meridional differences in internal dimensions of the anterior segment in human eyes evaluated with 2 imaging systems.

Abstract:

PURPOSE:To evaluate meridional differences in angle-to-angle (A-A) and sulcus-to-sulcus (S-S) dimensions in human eyes using very high frequency ultrasound (VHF US) and anterior segment optical coherence tomography (AS-OCT). SETTING:John A. Moran Eye Center, University of Utah, USA; Berlin Eye Research Institute, Germany; Quattroelle Centri Oftalmochirurgici, Italy. METHODS:Human autopsy eyes were fixated to special eye holders and had anterior segment scanning using 50 MHz ultrasound (Artemis, Ultralink) (20 eyes) and AS-OCT (SL-OCT, Heidelberg Engineering) (24 eyes). Seventy-three eyes (58 patients) also had anterior segment scanning using the same systems (Artemis, 50 eyes; SL-OCT, 23 eyes). Four meridians were evaluated in each eye. The A-A dimensions were measured by VHF US and AS-OCT. The S-S dimensions were also measured by VHF US. Statistical analyses were done with the Huynh-Feldt test. RESULTS:In the autopsy-eye study, the differences in A-A and S-S dimensions between the 4 meridians in eyes analyzed with VHF US were statistically significant (P=.002 and P=.009, respectively). The differences in A-A dimensions in eyes analyzed with the AS-OCT were also significant (P=.005). The same findings were observed in the clinical study (VHF US, P=.001 for A-A and P<.001 for S-S; AS-OCT, P<.001 for A-A). CONCLUSIONS:This study suggests that the internal geometry of the anterior segment of human eyes does not constitute a circle. This may have significant relevance for the accurate sizing of phakic intraocular lenses.

authors

Werner L,Lovisolo C,Chew J,Tetz M,Müller M

doi

10.1016/j.jcrs.2008.03.033

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

1125-32

issue

7

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(08)00413-6

journal_volume

34

pub_type

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