Abstract：
PURPOSE:To investigate the effect of surface modification of poly(methyl methacrylate) (PMMA) by poly(ethylene glycol) (PEG) grafting on cell adhesion. SETTING:Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea. METHODS:The PMMA surface was oxidized with ozone, and PEG acrylate was then graft polymerized. To verify the PEG grafting on the surface, the oxygen content was measured by electron spectroscopy for chemical analysis. The contact angle was measured using the Wilhelmy plate method. The adhesion of keratocytes on modified PMMA was investigated in vitro. Cultured rabbit keratocytes (4 x10(5) cells/mL) were layered on each PMMA disk, cultured in a carbon dioxide incubator for 24 hours, harvested by trypsinization, and counted. A commercially available intraocular lens was modified as described and then inserted in the anterior chamber of a white rabbit. The cell adherence pattern on the modified IOL was examined by scanning electron microscopy. RESULTS:The PEG-grafted PMMA revealed a higher oxygen content and lower dynamic receding contact angles than the untreated PMMA. The mean number of adhered cells was 72.5 +/- 22 x 10(4)/mL for untreated PMMA. After PEG grafting of 1 hour and ozone oxidation of 2 hours, the adherent cell counts significantly decreased to 6.5 +/- 1.7 x 10(4)/mL and 7.6 +/- 1.6 x 10(4)/mL, respectively (P =.002). Scanning electron microscopy showed small round cells sparsely scattered on the modified PMMA in contrast to the untreated PMMA. CONCLUSION:Surface modification of PMMA using PEG grafting reduced cell adhesion. This may decrease the incidence of retroprosthetic membrane formation after keratoprosthesis surgery.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Kim MK,Park IS,Park HD,Wee WR,Lee JH,Park KD,Kim SH,Kim YHdoi
10.1016/s0886-3350(00)00701-xsubject
Has Abstractpub_date
2001-05-01 00:00:00pages
766-74issue
5eissn
0886-3350issn
1873-4502pii
S0886-3350(00)00701-Xjournal_volume
27pub_type
杂志文章abstract：PURPOSE:To demonstrate the use of polar value analysis of surgically induced astigmatism (SIA). SETTING:Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark. METHODS:Univariate polar value analysis of SIA was demonstrated for a single patient and for aggregate data. Bivariate polar value analysis wa...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(00)00799-9
更新日期：2001-01-01 00:00:00
abstract：:The excimer laser is potentially capable of achieving wide area central corneal reprofiling because of its extreme precision and limited penetration into adjacent tissues. A beam modifying system designed for this application is described. Initial clinical studies in monkeys and in ten human patients with blind eyes w...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(89)80055-0
更新日期：1989-07-01 00:00:00
abstract：PURPOSE:To evaluate the effect of a capsular tension ring (CTR) on the shape of the capsular bag, the extent of the capsular opening, and the shape of intraocular lenses (IOLs). SETTING:Department of Ophthalmology, College of Medicine, The Catholic University of Korea, Seoul, Korea. METHODS:The corneal button was rem...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(00)00610-6
更新日期：2001-03-01 00:00:00
abstract：PURPOSE:To evaluate the use of 2-photon microscopy (TPM), which excites tissue autofluorescence, in detecting and calculating the grade of collagen corneal crosslinks, which are not visible through the slitlamp and in vivo confocal microscopy. SETTING:Departments of Ophthalmology, University of Lübeck, Lübeck, and Uni...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.06.068
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:To evaluate the repeatability and reproducibility of anterior chamber volume (ACV) measurements using swept-source 3-dimensional corneal and anterior segment optical coherence tomography (CAS-OCT) and dual Scheimpflug imaging. SETTING:Department of Ophthalmology, Institute of Clinical Medicine, University of T...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.jcrs.2010.08.053
更新日期：2011-03-01 00:00:00
abstract：:Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14.0 mm Hg) and at 72 hours (average IOP 11.6 mm Hg) (P less than .001). The per...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(88)80034-8
更新日期：1988-11-01 00:00:00
abstract：PURPOSE:To analyze anterior segment structure changes during accommodative stimuli after monofocal intraocular lens (IOL) implantation using 2 ultrasound biomicroscopy (UBM) systems. SETTING:Department of Ophthalmology, University of Verona, Verona, Italy. METHODS:Twenty-six eyes (23 patients) with 1 of 4 monofocal I...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.02.018
更新日期：2008-06-01 00:00:00
abstract：:The ergonomics of ocular surgery has received little attention even though the usual positioning of the patient and surgeon during traditional cataract surgery places the surgeon at risk for back, neck, and arm strain. The recent development of the temporal cataract incision allows the operating microscope to be tilte...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(99)80122-9
更新日期：1999-02-01 00:00:00
abstract：:A 58-year-old woman had successful phacoemulsification with intraocular lens (IOL) implantation in January 2001. Two years later, nonpenetrating glaucoma surgery with mitomycin-C (MMC) 0.02% was performed for uncontrolled glaucoma. Two months later, opacification of the anterior IOL surface was observed. The IOL was r...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.07.038
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To report the clinical outcomes of implantation of a new Ferrara intrastromal corneal ring segment (ICRS) with a 210-degree arc length in eyes with keratoconus. SETTING:Private eye clinic, Belo Horizonte, Brazil METHODS:Statistical analysis included preoperative and postoperative uncorrected distance visual a...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.04.035
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To investigate whether caffeic acid phenethyl ester (CAPE) prevents sodium-selenite-induced cataract. SETTING:Department of Ophthalmology and Biochemistry, Inonu University Medical Faculty, Turgut Ozal Medical Center, Research Hospital, Malatya, Turkey. METHODS:Sixty Sprague-Dawley rat litters were randomized...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(02)01242-7
更新日期：2002-08-01 00:00:00
abstract：:Postoperative lens capsule opacification is a complication of extracapsular cataract extraction. To avoid this problem, we aspirated the epithelial cells lining the internal surface of the capsular bag. Anterior capsule specimens collected three and six years after the first surgical intervention (extracapsular catara...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80302-1
更新日期：1993-05-01 00:00:00
abstract：PURPOSE:To analyze risk factors and management of pupillary intraocular lens (IOL) capture after IOL transscleral fixation. SETTING:Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea. DESIGN:Retrospective case series. METHODS:A chart review was performed of patients who had transscle...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.08.021
更新日期：2017-12-01 00:00:00
abstract：:Subluxated cataractous and clear lenses are commonly treated by limbal or pars plana lensectomy followed by primary or secondary intraocular lens (IOL) implantation. Adjunctive capsular prosthetic devices have facilitated lens removal and IOL centration in these challenging cases but have also added complexity and pot...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.05.019
更新日期：2009-10-01 00:00:00
abstract：:The management of malignant glaucoma involves either anterior vitrectomy with zonulectomy and iridectomy or 3-port core pars plana vitrectomy (PPV) by retinal surgeons. The proposed modification can be performed with reasonable success rates. In this technique, synechiolysis and anterior chamber irrigation is performe...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000519
更新日期：2020-11-23 00:00:00
abstract：PURPOSE:To evaluate the long-term therapeutic efficacy of phacoemulsification with intraocular lens (IOL) implantation in treating phacomorphic glaucoma. SETTING:Ophthalmology Department, Maryknoll Hospital, Busan, Korea. METHODS:This study evaluated eyes that had phacoemulsification with IOL implantation to treat ph...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.11.023
更新日期：2010-05-01 00:00:00
abstract：:Twenty-eight epikeratophakia procedures have been performed at the University of Minnesota since December 1985. This report describes several technique modifications and compares the refractive and visual outcome of these cases with the national results. There have been 17 aphakic cases (13 adult and four pediatric), ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(89)80091-4
更新日期：1989-05-01 00:00:00
abstract：:Multifocal intraocular lenses (MIOLs) have been designed to provide better uncorrected near visual acuity than monofocal IOLs. However, the increase in depth of focus is combined with a significant decrease in contrast sensitivity and glare. We implanted a new zonal-progressive MIOL (AMO Array) in 31 eyes of 25 patien...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(13)80217-9
更新日期：1995-09-01 00:00:00
abstract：PURPOSE:To compare changes in intraocular pressure (IOP) during femtosecond laser pretreatment of cataract between glaucomatous eyes and nonglaucomatous eyes. SETTING:Launceston Eye Institute and Launceston Eye Hospital, Launceston, Australia. DESIGN:Nonrandomized interventional prospective case series. METHODS:Pati...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.10.026
更新日期：2015-02-01 00:00:00
abstract：PURPOSE:To compare short-term refractive and visual acuity outcomes after topography-guided laser in situ keratomileusis (LASIK) planned with a new topography analysis system to those based on the manifest refraction. SETTING:Four clinical sites in the United States. DESIGN:Double-arm, nonmasked, nonrandomized retros...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000176
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:To determine the physical and mechanical conditions of an impacting air bag that causes corneal rupture in a post-radial keratotomy (RK) eye using a simulation model of the human eye. SETTING:Numerical simulation study on a computer. METHODS:The simulations were performed by a computer using the finite elemen...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)00966-x
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:To evaluate the relationship between the thinnest point in corneal thickness and the refractive state, keratometry, age, sex, and the ocular side. SETTING:Eye clinics in Germany and Austria and the Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. DESIGN:Cross-section...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.06.033
更新日期：2011-12-01 00:00:00
abstract：:A specially designed grid and software used to assess the postoperative rotation of a toric intraocular lens (IOL) are described. Postoperatively, a digital retroillumination image of the patient is taken and this image is superimposed on the grid. The software determines the center of the IOL. A prominent episcleral ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.10.057
更新日期：2009-03-01 00:00:00
abstract：UNLABELLED:We highlight potential problems and pitfalls in cases of Salzmann nodular degeneration by reporting the case of an 84-year-old man with reduced visual acuity due to particularly extensive bilateral Salzmann nodules and moderate cataracts. Large annular Salzmann lesions were removed by superficial keratectomy...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.10.037
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of incisional goniotomy as an adjunct to phacoemulsification in primary angle-closure glaucoma (PACG) patients. METHODS:In this prospective interventional case series, consecutive patients with PACG (high or borderline IOP) deemed fit for ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000481
更新日期：2020-11-19 00:00:00
abstract：UNLABELLED:We present a technique that uses a near-point string to demonstrate the anticipated near point of multifocal and accommodating intraocular lenses (IOLs). Beads are placed on the string at distances corresponding to the near points for diffractive and accommodating IOLs. The string is held up to the patient's...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.04.003
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To assess the safety and effectiveness of an immunotoxin, MDX-RA, designed to inhibit posterior capsule opacification (PCO). SETTING:Eleven private practices in the United States. METHODS:This study comprised 63 eyes of 63 patients having extracapsular cataract extraction by phacoemulsification; these patient...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0886-3350(98)80352-0
更新日期：1998-12-01 00:00:00
abstract：:A 60-year-old white man had cataract surgery with an AcrySof IQ intraocular lens (IOL) implanted in the right eye and a Tecnis IOL implanted in the left eye. The ocular spherical aberration (SA) target for a 6.0 mm pupil was +0.10 microm for the right eye and 0 microm for the left eye. After surgery, the ocular SA in ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.12.041
更新日期：2009-05-01 00:00:00
abstract：:A simple technique for the accurate surgical alignment of toric phakic and aphakic intraocular lenses (IOLs) is described. The mathematical relationship between toric misalignment and cylinder error is reviewed to demonstrate the importance of toric lens alignment in the setting of increased rotational stability with ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.04.041
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To compare the glare-type photic phenomena for a new intraocular lens (IOL) to other monofocal IOLs, and to investigate how IOL design features might affect these phenomena. SETTING:Alcon Laboratories, Inc., Fort Worth, Texas; John A Moran Eye Center, University of Utah, Salt Lake City, USA. DESIGN:Schematic ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.09.017
更新日期：2019-02-01 00:00:00
