Abstract:
PURPOSE:To investigate whether caffeic acid phenethyl ester (CAPE) prevents sodium-selenite-induced cataract. SETTING:Department of Ophthalmology and Biochemistry, Inonu University Medical Faculty, Turgut Ozal Medical Center, Research Hospital, Malatya, Turkey. METHODS:Sixty Sprague-Dawley rat litters were randomized into 3 groups. In Group 1 (n = 18), sodium selenite (30 nmol/g body weight) was injected subcutaneously on postpartum day 10. In Group 2 (n = 22), subcutaneous CAPE (15 micromol/kg) and sodium selenite (30 nmol/g body weight) were injected on postpartum day 10. The CAPE dose was continued subcutaneously for 3 days after the initial injection. Only subcutaneous saline was injected in Group 3 (control, n = 20). The development of cataract was assessed weekly, and its density was graded by slitlamp biomicroscopy and photography. Removed rat lenses were analyzed for glutathione (GSH) and malondialdehyde (MDA, marker of lipid peroxidation). RESULTS:Group 2 rats had clear lenses or minor cataract. All Group 1 rats developed more severe cataract or complete opacification. The between-group difference was statistically significant (P <.05). All control lenses (Group 3) were clear. The mean GSH level in Group 1 (4.49 micromol/g wet weight +/- 0.93 [SD]) was significantly lower than that in Group 2 (8.63 +/- 0.88 micromol/g wet weight) (P <.05) and controls (10.76 +/- 1.97 micromol/g wet weight) (P <.05). The mean MDA level in Group 1 (8.54 +/- 1.31 nmol/g wet weight) was significantly higher than that in Group 2 (5.23 +/- 0.84 nmol/g wet weight) (P <.05) and controls (4.19 +/- 0.81 nmol/g wet weight) (P <.05). CONCLUSIONS:Caffeic acid phenethyl ester effectively suppressed cataract formation in rats. The protective effect was supported by lower GSH and higher MDA levels in Group 1 than in Group 2, suggesting the antioxidant efficacy of this agent. Since CAPE has no known harmful effect on normal cells, it may be beneficial in clinical use in humans.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Doganay S,Turkoz Y,Evereklioglu C,Er H,Bozaran M,Ozerol Edoi
10.1016/s0886-3350(02)01242-7subject
Has Abstractpub_date
2002-08-01 00:00:00pages
1457-62issue
8eissn
0886-3350issn
1873-4502pii
S0886335002012427journal_volume
28pub_type
杂志文章abstract:PURPOSE:To assess the repeatability and validity of lens densitometry derived from the Pentacam Scheimpflug imaging system. SETTING:Eye Clinic, Queensland University of Technology, Brisbane, Australia. METHODS:This prospective cross-sectional study evaluated 1 eye of subjects with or without cataract. Scheimpflug mea...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.03.017
更新日期:2009-07-01 00:00:00
abstract:UNLABELLED:A 77-year-old woman with primary open-angle glaucoma was referred for surgical evaluation after failing to achieve target intraocular pressure (IOP) despite previous combined phacotrabeculectomy and Ahmed valve implantations. The IOP prior to surgery was 28 mm Hg on topical dorzolamide-timolol, latanoprost, ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.06.017
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To examine whether clinically significant differences exist in corneal elevation data from a sampling of countries worldwide. SETTING:International multicenter. DESIGN:Evaluation of diagnostic test or technology. METHODS:One randomly selected eye of normal adults from 8 countries spanning 6 continents was ex...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jcrs.2011.04.030
更新日期:2011-10-01 00:00:00
abstract::Fifteen eyes with an initial myopia between -5.00 diopters (D) and -12.00 D were treated with radial keratotomy (RK) followed by photorefractive keratectomy (PRK) at least 6 months later and observed for 6 months to 24 months. Five eyes that had penetrating keratoplasty (PKP) were treated for residual ametropia by PRK...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80130-7
更新日期:1995-05-01 00:00:00
abstract::We compared the effect of biconvex and convex-plano (posterior plano) intraocular lenses on posterior capsule opacification (PCO) following continuous curvilinear capsulorhexis (CCC) in 212 eyes. During the three years following surgery, the cumulative frequency of neodymium:YAG laser posterior capsulotomy, calculated...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80569-x
更新日期:1995-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of epithelial-disruption collagen crosslinking (CXL) for progressive keratoconus using a corneal disruptor device and a riboflavin solution designed for a transepithelial technique. SETTING:Magna Graecia University Eye Clinic, Catanzaro, Italy. DESIGN:Prospective comparative case seri...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2013.05.022
更新日期:2013-08-01 00:00:00
abstract::We report a case of toxic anterior segment syndrome (TASS) that developed after cataract surgery. A 78-year-old woman had uneventful phacoemulsification via a clear corneal incision with implantation of an acrylic intraocular lens. One day postoperatively, diffuse corneal edema and anterior chamber inflammation were e...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.07.052
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To examine the outcomes of photoastigmatic refractive keratectomy using corneal and refractive parameters for myopia and astigmatism in eyes with forme fruste and mild keratoconus. SETTING:Private practice, Melbourne, Australia. METHODS:Photoastigmatic refractive keratectomy was performed with a Star 1 or Sta...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2006.12.014
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:Comparison of lens capsule-related complications resulting from femtosecond laser-assisted capsulotomy and manual capsulorhexis in patients with white cataracts. SETTING:Eye Center, Second Affiliated Hospital, Zhejiang Medical School, Hangzhou, China. DESIGN:Prospective consecutive nonrandomized comparative c...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2018.10.037
更新日期:2019-03-01 00:00:00
abstract::Long-term stability of intrastromal corneal ring segments is important in maintaining patients' corrected distance visual acuity and avoiding injury to the local tissues. We report a case of traumatic shattering of intrastromal segments due to blunt trauma, with successful removal of the fragments. ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2010.03.022
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:To investigate the effect of surface modification of poly(methyl methacrylate) (PMMA) by poly(ethylene glycol) (PEG) grafting on cell adhesion. SETTING:Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea. METHODS:The PMMA surface was oxidized with ozone, and PEG acrylate was then gra...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(00)00701-x
更新日期:2001-05-01 00:00:00
abstract::In 1984, our ophthalmology department switched from intracapsular cataract extraction (ICCE) to extracapsular cataract extraction (ECCE). We reviewed the postoperative incidence of retinal detachment (RD) in two consecutive series: (1) 604 eyes operated on by ICCE from 1982 to 1983 and (2) 1726 eyes operated on by ECC...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80498-1
更新日期:1995-03-01 00:00:00
abstract::We report a case of bacterial keratitis that occurred after implantation of intrastromal corneal ring segments (Intacs). The patient presented with decreased vision, inflammation, and stromal infiltrates localized at the extremity of an Intacs channel 3 months after surgery. Culture were positive for Clostridium perfr...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(02)01484-0
更新日期:2003-02-01 00:00:00
abstract::We performed morphometric analysis of the central corneal endothelium on 24 eyes of 19 patients who had had anterior radial keratotomy. The endothelium was analyzed for a variety of parameters, including cell area, perimeter, side lengths, cell shape, and number of sides. Mean, standard deviation, and coefficient of v...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(87)80068-8
更新日期:1987-05-01 00:00:00
abstract:PURPOSE:To assess the degree of capsular bag opacification in human cadaver eyes with silicone intraocular lenses (IOLs), specifically comparing the differences between round-edged IOLs and modern square-edged IOLs. SETTING:John A. Moran Eye Center, University of Utah, USA. DESIGN:Experimental study. METHODS:The eye...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2010.10.058
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To test the performance of 4 tonometers in estimating intraocular pressure (IOP) after 3 forms of refractive surgery. SETTING:Eye Hospital, Wenzhou Medical University, China. DESIGN:Prospective case series. METHODS:Patients matched for preoperative age, corneal thickness, and myopic correction enrolled for f...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1097/j.jcrs.0000000000000204
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To study the perception of light distortion after refractive lens exchange (RLE) with diffractive multifocal intraocular lenses (IOLs). SETTING:Clínica Oftalmológica das Antas, Porto, Portugal. DESIGN:Retrospective comparative study. METHODS:Refractive lens exchange was performed with implantation of an AT L...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.07.033
更新日期:2015-03-01 00:00:00
abstract::A survey of intraocular lens (IOL) explantations performed during the 1984 calendar year requested dates of implantation and explantation, lens manufacturer, and lens style for anterior chamber, posterior chamber, and iris-supported lenses. The survey was distributed to 3,640 members of the American Society of Catarac...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(86)80078-5
更新日期:1986-11-01 00:00:00
abstract::A prospective randomized study was performed involving 200 patients divided into four groups: (1) Healon aspirated, (2) Amvisc aspirated, (3) Viscoat aspirated, and (4) Viscoat not aspirated. Postoperative intraocular pressures were measured at 4, 8, and 24 hours, two to three days, and one month. Significant differen...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(89)80060-4
更新日期:1989-07-01 00:00:00
abstract:PURPOSE:To examine changes in visual, psychological, and functional disability in older people waiting for cataract extraction and 6 months after surgery. SETTING:Community-based study in Northeast England. METHODS:Participants were 92 patients (mean age 78.1 years +/- 6.5 [SD], 79% female) with age-related cataract....
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.07.040
更新日期:2006-01-01 00:00:00
abstract::We present a series of nine cases involving primary intraocular lens implantation in congenital cataracts. Because of the problems encountered with the technique used in the earlier cases, we developed a new surgical technique that may be described as primary epilenticular posterior chamber lens implantation followed ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(88)80088-9
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:To compare the long-term refractive effects of small-incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) on the correction of high myopia and astigmatism. SETTING:The Eye and ENT Hospital of Fudan University, Shanghai, China. DESIGN:Retrospective case s...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1097/j.jcrs.0000000000000075
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To evaluate the results and complications of hyperopic laser in situ keratomileusis (LASIK) with a low-energy femtosecond laser and non-custom tissue-saving ablation profile. SETTING:Private practice, Siena, Italy. DESIGN:Case series. METHODS:Hyperopic eyes with a spherical equivalent (SE) between +1.0 and +...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2013.11.031
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:To compare the results of 2 intraocular lens (IOL) implantation techniques in pediatric cataract surgery. SETTING:Labbafinejad Medical Center, Tehran, Iran. METHODS:This contralateral prospective randomized study comprised children with bilateral congenital or developmental cataract. In all cases, anterior ca...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcrs.2009.02.017
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:To propose the new anterior-posterior method (A-P method) that does not require historical data to calculate intraocular lens (IOL) power after laser in situ keratomileusis (LASIK) and to compare the accuracy of the method with other IOL formulas after LASIK. SETTING:Keio University Hospital, Tokyo, Japan. DE...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2012.10.044
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:To study the intraocular pressure (IOP) as a prognostic indicator on the first day after combined phacoemulsification and nonpenetrating deep sclerectomy. SETTING:Ramón y Cajal Hospital, Madrid, Spain. METHODS:This retrospective study included 70 eyes of 70 patients who had combined phacoemulsification-nonpen...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2008.04.025
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To assess the effect of preoperative tear function on early changes in functional visual acuity (FVA) after laser in situ keratomileusis (LASIK). SETTING:Minamiaoyama Eye Clinic, Tokyo, Japan. METHODS:This prospective single-center study assessed the effect of preoperative and postoperative tear functions on ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2004.02.086
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:To present contact-angle measurements of commercially available intraocular lenses (IOLs) in air and in water to facilitate the understanding of how various IOLs might interact in different environments. SETTING:Laboratory. METHODS:Five commercially available IOLs were studied: AMO DuraLens PS-59NB. AMO Phaco...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(98)80322-2
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:To compare corneal astigmatism measurements obtained using a new optical biometer (AL-Scan) and a standard biometer based on partial coherence interferometry (IOLMaster 500) for toric intraocular lens (IOL) selection. SETTING:Siriraj Hospital, Mahidol University, Bangkok, Thailand. DESIGN:Prospective comparat...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.06.029
更新日期:2015-02-01 00:00:00
abstract::A generally healthy and independent 83-year-old man presented with long-standing, mild to moderate glaucoma. He had uneventful cataract surgery several years earlier. He also had previous selective laser trabeculoplasty (SLT) with only slight reduction in his intraocular pressure (IOP). His untreated IOP was middle to...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1097/j.jcrs.0000000000000244
更新日期:2020-06-01 00:00:00