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Two episodes of anaphylaxis following exposure to hydroxypropyl methylcellulose during cataract surgery.

Abstract：

UNLABELLED:We report a case of immediate severe anaphylaxis to hydroxypropyl methylcellulose (HPMC) on 2 separate occasions during cataract surgery in a 71-year-old patient. Skin prick tests were positive for HPMC, a constituent of Ocucoat and Xylocaine gel, which were administered intraocularly during surgery. Skin prick tests were also positive for methylcellulose. Based on symptoms and clinical signs of anaphylaxis following 2 separate cataract operations together with positive prick tests to HPMC, HPMC is the most plausible cause of the reactions. The patient has since had uneventful surgery for a detached retina avoiding HPMC. This case stresses the importance of considering all medication given to patients as possible causes of an anaphylactic reaction. FINANCIAL DISCLOSURE:No author has a financial or proprietary interest in any material or method mentioned.

journal_name

J Cataract Refract Surg

journal_title

Journal of cataract and refractive surgery

authors

Munk SJ,Heegaard S,Mosbech H,Garvey LH

doi

10.1016/j.jcrs.2013.02.034

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

948-51

issue

6

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(13)00226-5

journal_volume

39

pub_type

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