Preliminary study of sural nerve morphological changes in uremic hemodialysis patients using 22-MHz high-frequency ultrasound.

Abstract:

INTRODUCTION:The aim of this study was to evaluate the ultrasound (US) morphological changes of sural nerves (SNs) of uremic patients on hemodialysis. METHODS:Sixty-six SNs in 33 uremic patients were examined by 22-MHZ high-frequency US and routine nerve conduction studies (NCS), and 76 SNs in 38 controls were also examined. Cross-sectional area (CSA) and maximal fascicular thickness (MFT) of the SNs were measured. RESULTS:The inner parts of the SN were clearly identified in all participants. There were significant increases in CSA and MFT in the patient group (1.86 ± 0.53 mm(2) and 0.37 ± 0.08 mm, respectively) compared with the control group (1.38 ± 0.25 mm(2) and 0.32 ± 0.03 mm, respectively) (P < 0.001). Fifty-seven SNs (86.36%) had abnormal CSAs, and 51 SNs (77.27%) had abnormal MFTs in the patient group, which was higher than NCS abnormalities (66.67%). CONCLUSIONS:A 22-MHZ US can show morphological changes in the SNs of uremic patients and may be a valuable tool.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Wei M,Zhu J,Wang N,Xue Q,Liu F,Hu B,Fang J,Zhang Y

doi

10.1002/mus.23418

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

937-42

issue

6

eissn

0148-639X

issn

1097-4598

journal_volume

46

pub_type

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