Abstract：
:Interleukin-15 (IL-15) is a cytokine that has been proposed to modulate skeletal muscle and adipose tissue mass. In the present study, an F(2) resource population of Gushi chickens crossed with Anka broilers was used to investigate the genetic effects of the chicken IL-15 gene. Two single nucleotide polymorphisms (SNPs) (g.31224G>A and g.31266T>G) were identified in exon 5 of the IL-15 gene by means of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing. Associations between the two SNPs and chicken fatness and muscle fiber traits were determined using linkage disequilibrium, haplotype construction, and association analysis. Both of the SNPs were associated with abdominal fat weight, leg muscle fiber diameter, and leg muscle fiber density (p < 0.05). Haplotypes of the two linked SNPs were associated with abdominal fat weight, fat thickness under the skin, and leg muscle fiber diameter (p < 0.05). The results suggested that the IL-15 gene might be associated with the causative mutation or the quantitative trait locus (QTL) controlling the fatness traits and muscle fiber traits in chickens.
journal_name
J Appl Genetjournal_title
Journal of applied geneticsauthors
Lv SJ,Su L,Li H,Han RL,Sun GR,Kang XTdoi
10.1007/s13353-012-0111-3subject
Has Abstractpub_date
2012-11-01 00:00:00pages
443-8issue
4eissn
1234-1983issn
2190-3883journal_volume
53pub_type
杂志文章abstract：:Investigations on the impact of chemicals on the environment and human health have led to the development of an exposome concept. The exposome refers to the totality of exposures received by a person during life, including exposures to life-style factors, from the prenatal period to death. The exposure to genotoxic ch...
journal_title：Journal of applied genetics
pub_type： 杂志文章,评审
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abstract：:Candida sp. have been responsible for an increasing number of infections, especially in patients with immunodeficiency. Species-specific differentiation of Candida sp. is difficult in routine diagnosis. This identification can have a highly significant association in therapy and prophylaxis. This work has shown a new ...
journal_title：Journal of applied genetics
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abstract：:Fast and efficient DNA fingerprinting of crop cultivars and individuals is frequently used in both theoretical population genetics and in practical breeding. Numerous DNA marker technologies exist and the ratio of speed, cost and accuracy are of importance. Therefore even in species where highly accurate and polymorph...
journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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abstract：:Mycotoxins are secondary metabolites with potential dangers for animal and human health. In particular, maize (Zea mays L.) infection caused by Fusarium and the consequent fumonisin contamination is widespread in several countries such as Italy. We developed six maize populations differing in their constitution of reg...
journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
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doi：10.1007/s13353-015-0272-y
更新日期：2015-08-01 00:00:00
abstract：:Recent evidence indicates an important role of inflammation pathways, airways remodeling and epithelium activation in asthma genetics. In particular, transcriptome studies have detected differentially expressed genes involved in eosinophil apoptosis, the arginase pathway, response to allergens or interleukins, and to ...
journal_title：Journal of applied genetics
pub_type： 杂志文章,评审
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更新日期：2005-01-01 00:00:00
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journal_title：Journal of applied genetics
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doi：10.1007/s13353-020-00564-6
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/BF03195222
更新日期：2007-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Journal of applied genetics
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doi：
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journal_title：Journal of applied genetics
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doi：
更新日期：2003-01-01 00:00:00
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journal_title：Journal of applied genetics
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abstract：:SDS-PAGE analysis of seed globulins covered 200 accessions of the following Lens taxa: L. culinaris subsp. culinaris, L. culinaris subsp. orientalis, L. odemensis, L. ervoides, L. nigricans, L. lamottei and L. tomentosus. The number of polypeptide bands detected in particular taxa varied from 22 in L. lamottei to 35 i...
journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/s13353-012-0105-1
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journal_title：Journal of applied genetics
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doi：
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journal_title：Journal of applied genetics
pub_type： 杂志文章
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journal_title：Journal of applied genetics
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doi：10.1007/s13353-014-0226-9
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journal_title：Journal of applied genetics
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doi：
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journal_title：Journal of applied genetics
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doi：
更新日期：2005-01-01 00:00:00
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journal_title：Journal of applied genetics
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journal_title：Journal of applied genetics
pub_type： 杂志文章
doi：10.1007/BF03195698
更新日期：2009-01-01 00:00:00
