Adenylate cyclase responses and biochemical characterization of primary rabbit proximal tubular cell cultures and LLC-PK1 cells.

abstract：:Cognitive dysfunction is a well-known complication of chronic renal failure that is evident in 30% of hemodialysis (HD) patients. However, the pathogenesis of this dysfunction is unknown. Left ventricular hypertrophy could develop in hypertensive HD patients without establishing normovolemia. Our aim was to evaluate t...

journal_title：Renal failure

authors： Dogukan A,Guler M,Yavuzkir MF,Tekatas A,Poyrazoglu OK,Aygen B,Gunal AI,Yoldas TK

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Human urotensin-II (hU-II) is one of the most potent vasoconstrictors in mammals. To our knowledge, there is no study about the role of U-II in childhood glomerulonephritis. We first determined the expression of h U-II in kidneys of children with chronic glomerular diseases. METHODS:Normal human kidneys wer...

journal_title：Renal failure

authors： Balat A,Karakök M,Yilmaz K,Kibar Y

更新日期：2007-01-01 00:00:00

abstract：:The present work examines the role of uremia and the effect of dialysis treatment on red blood cells (RBCs) membrane properties of hemodialysis patients. The results showed that, the uremic patients had a lower values of erythrocyte deformability than that of healthy control subject. The median osmotic fragility (MOF)...

journal_title：Renal failure

authors： Ibrahim FF,Ghannam MM,Ali FM

更新日期：2002-11-01 00:00:00

abstract：:Recent studies show that clinically stable renal transplant recipients have an increased prevalence of hyperhomocysteinemia (hyperHcy), but the mechanism of this disorder has not yet been elucidated. The aim of the present study was to evaluate the factors associated with hyperHcy after a successful renal transplantat...

journal_title：Renal failure

authors： Simić-Ogrizović S,Radivojević D,Radovic M,Lezaic V,Mirković D,Babić D,Dukanović L

更新日期：2006-01-01 00:00:00

abstract：:The characteristics of two established renal cell lines (LLC-PKI and OK) and of primary cultures of rabbit and human proximal tubule cells are described by summarizing the literature about specific properties retained by these cells in culture. Furthermore, comparative biochemical and functional properties are present...

journal_title：Renal failure

authors： Toutain H,Morin JP

更新日期：1992-01-01 00:00:00

abstract：:Neutrophil-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been shown to predict mortality in patients with malignancies, ischemic heart disease and peripheral vascular disease. Its prognostic value in hemodialysis patients is unclear. The aims of this study were to: (i) explore the relationship b...

journal_title：Renal failure

authors： Neuen BL,Leather N,Greenwood AM,Gunnarsson R,Cho Y,Mantha ML

更新日期：2016-01-01 00:00:00

abstract：:Acute renal failure (ARF) occurs in wide range of conditions, making the evaluation of its prognosis a difficult task. Data regarding prognostic factors in ARF in a general population in developing countries are scarce. The objective of the study was to describe predictors of mortality in ARF that are relevant in the ...

journal_title：Renal failure

authors： Kohli HS,Bhat A,Jairam A,Aravindan AN,Sud K,Jha V,Gupta KL,Sakhuja V

更新日期：2007-01-01 00:00:00

abstract：:A 68-year-old male presented with acute myeloid leukemia, renal failure, hypokalemia, and enlarged kidneys on renal ultrasound. Renal biopsy revealed massive leukemic infiltration of the kidney. After systemic chemotherapy, the patient developed tumor lysis syndrome followed by a phase of proximal tubule dysfunction p...

journal_title：Renal failure

authors： Rüger W,Kruip MJ,Betjes MG

更新日期：2009-01-01 00:00:00

abstract：:Vascular calcification (VC) is an important promoter of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD). Several indices can be used to evaluate VC, including the abdominal aortic calcification index (AACI) and carotid artery intima-media thickness (IMT); however, simpler and lesser expens...

journal_title：Renal failure

authors： Yang N,Yang W,Cui W,Zhou D,Du X,Li L

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00

abstract：:Cardiac dysfunction portends a poor prognosis in renal failure and vice versa. Functional abnormalities of heart in patients with renal insufficiency were frequently noted. The aim of this study is to assess the relationship between left ventricular systolic and diastolic function and renal function in patients with v...

journal_title：Renal failure

authors： Hsieh MC,Su HM,Wang SY,Tsai DH,Lin SD,Chen SC,Chen HC

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To explore the association of urinary podocyte excretion and renal expression of podocyte-specific marker podocalyxin (PCX) with clinicopathological changes in immunoglobulin A nephropathy (IgAN). METHODS:Morning urine samples from IgAN patients and healthy controls were collected. The expression of glomerul...

journal_title：Renal failure

authors： Jiang WL,Peng YM,Liu YH,Liu H,Chen GC,Xu XQ,Zhu XJ,Liu FY

更新日期：2012-01-01 00:00:00

abstract：:Perioperative risk during coronary artery bypass grafting (CABG) is high in patients with chronic renal disease. We aimed to determine postoperative two-year mortality and identify the preoperative risk factors of mortality during CABG surgery in hemodialysis (HD)-dependent and HD-non-dependent CRF patients. We includ...

journal_title：Renal failure

authors： Akman B,Bilgic A,Sasak G,Sezer S,Sezgin A,Arat Z,Ozdemir FN,Haberal M

更新日期：2007-01-01 00:00:00

abstract：:Compared to prior studies which frequently pinpoint the impairment of one parameter or function, this paper reports for the first time an extensive characterization of the toxic effects of gentamicin in a single model of primary cultured rabbit proximal tubule cells developed without insulin and glucose. Biochemical, ...

journal_title：Renal failure

authors： Monteil C,Leclere C,Fillastre JP,Morin JP

更新日期：1993-01-01 00:00:00

abstract：:Background: Renal interstitial fibrosis is a common pathway of chronic kidney disease to end-stage renal disease, which is characterized by an imbalance between the synthesis and degradation of the collagen-rich extracellular matrix (ECM). While, discoidin domain receptor 2 (DDR2) can be activated when it binds to som...

journal_title：Renal failure

authors： Li X,Bu X,Yan F,Wang F,Wei D,Yuan J,Zheng W,Su J,Yuan J

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Despite the widespread availability of dialytic and intensive care unit technology, the probability of early mortality in critically ill patients with acute renal failure (ARF) is still high, and the evaluation of the patients' prognosis has been difficult. The Acute Physiology and Chronic Health Evaluation ...

journal_title：Renal failure

authors： Chen YC,Hsu HH,Kao KC,Fang JT,Huang CC

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The hemodialysis adequacy is one of the most important issues influencing the survival of patients on maintenance hemodialysis (HD). Assessment of measuring the delivered dialysis dose using clearance x time/volume (Kt/V) index requires multiple blood sampling. New methods for assessment of dialysis dose bas...

journal_title：Renal failure

authors： Racki S,Zaputović L,Maleta I,Grzetić M,Mavrić Z,Devcić B,Vujicić B

更新日期：2005-01-01 00:00:00

abstract：:Daily intraperitoneal (i.p.) injection of genatmicin at a dose of 70 mg/kg for 11 days produced nephrotoxicity in female Sprague-Dawley rats as evidenced by increased excretion of urinary protein and trypsin inhibitory activity as well as rise in renal individual class and total phospholipid. The observed proteinuria ...

journal_title：Renal failure

authors： Smetana S,Khalef S,Kopolovic G,Bar-Khayim Y,Birk Y,Kacew S

更新日期：1992-01-01 00:00:00

abstract：:The proximal convoluted tubule (PCT) is the major target for injury in gentamicin nephrotoxicity but the necrosis is often patchy and focal. The PCT is structurally, functionally, and metabolically heterogeneous, and the possibility of differential vulnerability to gentamicin-induced necrosis based on this heterogenei...

journal_title：Renal failure

authors： Shanley PF,Burke TJ

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Psychological problems such as depression and anxiety are common in hemodialysis patients. In several studies, exercise programs were effective in relieving depression or anxiety in these patients, although not all agree. PURPOSE:In this study, we evaluated the effects of an exercise program on exercise cap...

journal_title：Renal failure

authors： Suh MR,Jung HH,Kim SB,Park JS,Yang WS

更新日期：2002-05-01 00:00:00

abstract：:Herein, we report a case of acute kidney injury (AKI) due to diarrhea-induced acute tubular necrosis (ATN) in a patient with nephrotic syndrome secondary to biopsy-proven collapsing focal and segmental glomerulosclerosis (FSGS). The clinical picture mimicked rapidly progressive glomerulonephritis (RPGN) and motivated ...

journal_title：Renal failure

authors： Rodamilans MF,Barros LL,Carneiro MM,dos Santos WL,Rocha PN

更新日期：2010-01-01 00:00:00

abstract：AIM:Oxidative stress (OS) and endothelial dysfunction are implicated in accelerated atherosclerosis in chronic kidney disease (CKD). We assessed endothelial function, OS, and carotid intimal medial thickness (CIMT) and their correlates in 44 CKD stage 5 patients (group III) before and after hemodialysis (HD), 40 patien...

journal_title：Renal failure

authors： Khaira A,Mahajan S,Kumar A,Saraya A,Tiwari SC,Prakash S,Gupta A,Bhowmik D,Agarwal SK

更新日期：2011-01-01 00:00:00

abstract：:The aim of our study was to analyze the clinical course and outcome of acute renal failure (ARF) in patients with hemorrhagic fever with renal syndrome (HFRS). From 1983 to 1995, we treated 33 patients (27 males, 6 females) aged from 16 to 71 years. Half of patients were connected with work at a farm or in a forest. T...

journal_title：Renal failure

authors： Bren AF,Pavlovcic SK,Koselj M,Kovac J,Kandus A,Kveder R

更新日期：1996-07-01 00:00:00

abstract：:The case records of 75 patients who had systemic lupus erythematosus (SLE) and renal involvement on renal histology were reviewed. There were 70 females and 5 males, with a ratio of 14:1. The majority of the patients were in their second and third decades of life. SLE nephritis was distinctly uncommon in patients belo...

journal_title：Renal failure

authors： Williams W,Shah D

更新日期：1990-01-01 00:00:00

abstract：:Synthetic arteriovenous grafts for hemodialysis constitute the second choice in comparison with native arteriovenous fistulas. Lower patency rates and significantly more frequent infections are the main disadvantages of hemodialysis grafts over fistulas. Infectious complications could vary between a simple local eryth...

journal_title：Renal failure

authors： Galanopoulos G,Lambidis C

更新日期：2014-05-01 00:00:00

abstract：:A multidisciplinary approach represents the best method to interact with patients. Neoplastic and renal diseases are closely related to each other because of an increased risk of cancer among individuals with end-stage renal disease and because of the high prevalence of renal failure in cancer patients. Physicians sho...

journal_title：Renal failure

authors： Lacava V,Coppolino G,Puntorieri E,Cernaro V,Lupica R,Visconti L,Buemi A,Santoro D,Buemi M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a leading cause of diabetes-related morbidity and mortality. The aim of this study was to evaluate the relationship of AGT M235T and apoprotein E (APO E) gene polymorphism with DN in Turkish patients of Type 2 diabetes, and to compare genotype and allele distributions among DN pa...

journal_title：Renal failure

authors： Reis KA,Ebinç FA,Koç E,Demirci H,Erten Y,Güz G,Derici UB,Bali M,Söylemezoğlu O,Arınsoy T,Sindel S

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:Mortality is a major problem in renal transplant patients, and appropriate preoperative evaluation is very important. We retrospectively reviewed the left ventricle ejection fraction (LVEF) of renal transplant patients. MATERIAL AND METHODS:The clinical records of 1763 patients who had preoperative LVEF result...

journal_title：Renal failure

authors： Ozkul F,Kasim Arik M,Erbiş H,Akbaş A,Yilmaz VT,Barutcu A,Ali Osmanoğlu I,Kocak H

更新日期：2016-11-01 00:00:00

abstract：:Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...

journal_title：Renal failure

authors： de Jesus Soares T,Costa RS,de Mattos Coelho R,Alves da Silva CG,Coimbra TM

更新日期：2005-01-01 00:00:00

abstract：:We present a patient with AL amyloidosis who had an autologous stem cell transplant (ASCT) over 9 years ago. She has since then developed slowly progressive renal insufficiency and the nephrotic syndrome. Hematologic evaluation has failed to identify recurrent disease and a renal biopsy demonstrated extensive amyloid ...

journal_title：Renal failure

authors： Rifkin SI,Weinstein SS

更新日期：2012-01-01 00:00:00