Effect of interaction between gentamicin and pyridoxal-5-phosphate on functional and metabolic parameters in kidneys of female Sprague-Dawley rats.

abstract：:Hypertonic glycerol injection is one of the most frequently used models of experimental acute renal failure. Late structural changes such as interstitial fibrosis in the renal cortex and tubular atrophy have been detected after severe acute tubular necrosis (ATN). The aim of this study was to investigate the expressio...

journal_title：Renal failure

authors： de Jesus Soares T,Costa RS,de Mattos Coelho R,Alves da Silva CG,Coimbra TM

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of lowering serum uric acid therapy on the progression of CKD to clarify the role of uric acid in the progression of CKD indirectly. METHODS...

journal_title：Renal failure

authors： Liu X,Zhai T,Ma R,Luo C,Wang H,Liu L

更新日期：2018-11-01 00:00:00

abstract：:Paraproteins or monoclonal proteins are the result of clonal B-cell or plasma cell proliferation of a malignant, premalignant or non-malignant nature. Monoclonal proteins may consist of intact immunoglobulin molecules or of heavy or light chains only. Depending on their rate of production and/or secretion they may acc...

journal_title：Renal failure

authors： Maniatis A

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:To show renal parenchymal injury depending on extracorporeal shock wave lithotripsy (ESWL). METHODS:The patients with one renal stone and in whom ESWL is planned among the patients in whom renal stone was determined. Their 24-h urine samples were collected just before and after the ESWL treatment. Cit (citr...

journal_title：Renal failure

authors： Ceylan C,Dogan S,Saydam G,Kocak MZ,Doluoglu OG

更新日期：2013-01-01 00:00:00

abstract：:Single injection, single blood sample, effective renal plasma flow (ERPF) estimated by 131I-orthoiodohippurate can be performed accurately and conveniently without urine collection at the bedside. The purpose of this study was to determine if ERPF early in the course of severe acute renal failure (ARF) predicts recove...

journal_title：Renal failure

authors： Holland MD,Galla JH,Dubovsky EV,Luke RG

更新日期：1987-01-01 00:00:00

abstract：:Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. The pathophysiologic mechanisms of diabetic nephropathy are incompletely understood but include overproduction of various growth factors and cytokines. Upregulation of vascular endothelial growth factor (VEGF) is a pathogenic even...

journal_title：Renal failure

authors： Patel L,Thaker A

更新日期：2014-07-01 00:00:00

abstract：:Kidney transplant recipients have increased risk of cancers when compared with the general population. Hepatocellular carcinoma (HCC) is extremely important in Asia where hepatitis B virus (HBV) infection is endemic. The aim is to study the epidemiological and clinical aspects of all de novo HCC in our kidney transpla...

journal_title：Renal failure

authors： Cheung CY,Lam MF,Chow KM,Lee W,Cheng YL,Yuen SK,Wong PN,Mo KL,Leung KT,Wong SH,Ho YW,Chau KF

更新日期：2014-07-01 00:00:00

abstract：:Toxoplasma gondii is one of the important opportunistic pathogen among solid-organ transplant recipients and hemodialysis patients (HD). This study was aimed to detect toxoplasmosis among 50 renal transplant recipients (RTR), 135 HD and 120 healthy individuals in two cities (Kashan and Qom) that located in the center ...

journal_title：Renal failure

authors： Rasti S,Hassanzadeh M,Soliemani A,Hooshyar H,Mousavi SG,Nikoueinejad H,Abdoli A

更新日期：2016-07-01 00:00:00

abstract：:Aims: The aim was to determine whether anti-neutrophil cytoplasmic antibody (ANCA)-positive serology in patients with lupus nephritis (LN) is associated with different clinicopathologic features and outcomes.Methods: In our retrospective analysis, 283 patients were enrolled between 2013 and 2018. Thirty-six patients w...

journal_title：Renal failure

authors： Wang S,Shang J,Xiao J,Zhao Z

更新日期：2020-11-01 00:00:00

abstract：:Recently, we demonstrated that furosemide improves renal hemodynamics and attenuates ischemia/reperfusion (I/R)-associated changes in angiogenesis-related gene expression. However, the effect of furosemide on I/R-induced apoptosis is not known. We utilized a rat model of acute ischemic nephropathy to test the hypothes...

journal_title：Renal failure

authors： Aravindan N,Aravindan S,Riedel BJ,Weng HR,Shaw AD

更新日期：2007-01-01 00:00:00

abstract：:The present study was undertaken to examine the role of arachidonic acid (AA) metabolites in hypoxia/reoxygenation (H/R)-induced renal cell injury in rabbit renal cortical slices using AA metabolic inhibitors. Inhibitors of cyclooxygenase (indomethacin and diclofenac sodium) and lipoxygenase pathways (nordihydroguaiar...

journal_title：Renal failure

authors： Kim YK,Hwang MY,Woo JS,Jung JS,Lee SH

更新日期：2000-03-01 00:00:00

abstract：:Medication errors are ongoing problems among hospitalized patients especially those with multiple co-morbidities and polypharmacy such as patients with renal diseases. This study evaluated the frequency, types and direct related cost of medication errors in nephrology ward and the role played by clinical pharmacists. ...

journal_title：Renal failure

authors： Gharekhani A,Kanani N,Khalili H,Dashti-Khavidaki S

更新日期：2014-09-01 00:00:00

abstract：:Renal ischemia-reperfusion injury is a leading cause of acute kidney injury, but its underlying mechanism remains poorly understood and effective therapies are still lacking. Here, we identified lncRNA XLOC_032768 as a novel target in renal ischemia-reperfusion injury by analyzing differentially expressed genes of the...

journal_title：Renal failure

authors： Zhou X,Li Y,Wu C,Yu W,Cheng F

更新日期：2020-11-01 00:00:00

abstract：:In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

journal_title：Renal failure

authors： Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

更新日期：2018-11-01 00:00:00

abstract：:Continuous efforts have been made to find out precise and simple method for determination of glomerular filtration rate (GFR). Cystatin C (cysteine proteinase inhibitor = CyC) is a low molecular weight (LMW) protein which is produced constantly by all nucleated cells independently of different pathological conditions ...

journal_title：Renal failure

authors： Jovanović D,Krstivojević P,Obradović I,Durdević V,Dukanović L

更新日期：2003-01-01 00:00:00

abstract：:Acute renal failure secondary to tumor infiltration of the kidneys is uncommon and largely described in patients with lymphoma or leukemia. We report a 64-year-old man previously diagnosed with limited stage small cell lung cancer who presented with acute renal failure (ARF). Renal imaging showed bilateral enlargement...

journal_title：Renal failure

authors： Wen YK,Chen ML

更新日期：2006-01-01 00:00:00

abstract：:The nephrotoxicity of amikacin (AK) was prevented with pentoxifylline (PTX) in a rat model. Rats were received a single injection of AK (1.2 g/kg, i.p.) with or without PTX pretreatment (25 mg/kg, orally). Renal morphology was investigated by light microscopy. Tissue samples and trunk blood were also obtained to deter...

journal_title：Renal failure

authors： Ozer MK,Asci H,Oncu M,Yesilot S,Savran M,Bayram D,Cicek E

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The pathogenesis of the development of IgA nephropathy has not been clear up to now. At present, some studies revealed that the mTOR pathway may participate in IgA nephropathy; however, the mechanism has not been systematically studied. In this study, we established an IgAN rat model to investigate the prote...

journal_title：Renal failure

authors： Guo N,Liu S,Bow LM,Cui X,Zhang L,Xu S,Lu S,Tian J

更新日期：2019-11-01 00:00:00

abstract：:The case of giant renal cyst measuring 30 cm, accompanied by abdominal swelling and erythrocytosis, is presented. A 45-year-old male presented with large abdominal mass, atrophic left kidney, hypertension, and erythrocytosis. The patient underwent multiple preoperative phlebotomies, open extirpation of the cyst, and n...

journal_title：Renal failure

authors： Pejcic T,Hadzi-Djokic J,Markovic B,Naumovic R

更新日期：2011-01-01 00:00:00

abstract：:Abnormal glucose metabolism in uremia may result from a complex interplay between decreased insulin secretion and insulin resistance. Recent studies report beneficial effect of biotin administration in glucose metabolism in diabetic animals and in a small number of patients with diabetes mellitus. The aim of the prese...

journal_title：Renal failure

authors： Koutsikos D,Fourtounas C,Kapetanaki A,Agroyannis B,Tzanatos H,Rammos G,Kopelias I,Bosiolis B,Bovoleti O,Darema M,Sallum G

更新日期：1996-01-01 00:00:00

abstract：:Compared to prior studies which frequently pinpoint the impairment of one parameter or function, this paper reports for the first time an extensive characterization of the toxic effects of gentamicin in a single model of primary cultured rabbit proximal tubule cells developed without insulin and glucose. Biochemical, ...

journal_title：Renal failure

authors： Monteil C,Leclere C,Fillastre JP,Morin JP

更新日期：1993-01-01 00:00:00

abstract：:Although sudden sensorineural hearing loss (SSNHL) affects chronic kidney disease (CKD) patients more frequently than non-CKD patients, few reports have described SSNHL in dialysis patients. We aimed to review the characteristics of SSNHL in chronic dialysis patients and evaluate treatment responses to steroid therapy...

journal_title：Renal failure

authors： Kang SM,Lim HW,Yu H

更新日期：2018-11-01 00:00:00

abstract：:At least 372 people developed crush syndrome after they were injured by the Great Hanshin-Awaji Earthquake. Of these, 23 were transferred to Osaka City General Hospital from the disaster area. The serum creatinine kinase (CK) of each of the 23 patients exceeded 10,000 IU/L. Sixteen of these patients were treated with ...

journal_title：Renal failure

authors： Shigemoto T,Rinka H,Matsuo Y,Kaji A,Tsukioka K,Ukai T,Shimaoka H

更新日期：1997-09-01 00:00:00

abstract：:Synthetic arteriovenous grafts for hemodialysis constitute the second choice in comparison with native arteriovenous fistulas. Lower patency rates and significantly more frequent infections are the main disadvantages of hemodialysis grafts over fistulas. Infectious complications could vary between a simple local eryth...

journal_title：Renal failure

authors： Galanopoulos G,Lambidis C

更新日期：2014-05-01 00:00:00

abstract：:In vascular smooth muscle, calcium overload is a highly pathogenic event, which increases with advancing age. An increase in the calcium content of arterial wall may be produced in rats by treatment with vitamin D3. The aim of this study was to evaluate the renal clearance of sulfanilamide (a model organic anion, pref...

journal_title：Renal failure

authors： Quaglia NB,Brandoni A,Ferri A,Torres AM

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Acquired cystic kidney disease (ACKD) is a frequent complication in chronic hemodialysis (HD) patients and a risk factor for renal cell carcinoma. Online hemodiafiltration (HDF) provides better clearance of middle molecular weight solutes, but its effect on ACKD has not been investigated. MATERIALS AND METH...

journal_title：Renal failure

authors： Weng CJ,Chang MY,Chen YC,Tian YC,Fang JT,Yang CW

更新日期：2009-01-01 00:00:00

abstract：:Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Endothelial dysfunction (ED), which is an early manifestation of vascular injury, has been shown in patients with ADPKD. Statins have a beneficial effect in the reversal of ED. Th...

journal_title：Renal failure

authors： Namli S,Oflaz H,Turgut F,Alisir S,Tufan F,Ucar A,Mercanoglu F,Ecder T

更新日期：2007-01-01 00:00:00

abstract：AIM:Occult hepatitis B virus (HBV) infection can be defined as the presence of HBV DNA in the liver and/or blood in the absence of detectable serum hepatitis B surface antigen (HBs Ag). There is a high prevalence of occult HBV infection in dialysis patients. This study investigated the prevalence of occult HBV infectio...

journal_title：Renal failure

authors： Sav T,Gursoy S,Torun E,Sav NM,Unal A,Oymak O,Utas C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Coagulation abnormalities have been reported in familial Mediterranean fever (FMF) patients with amyloidosis and nephrotic syndrome; but there is not enough data about the continuity of the thrombogenic activity in FMF patients in clinical remission. The purpose of this study was to assess thrombin activatab...

journal_title：Renal failure

authors： Bavbek N,Ceri M,Akdeniz D,Kargili A,Duranay M,Erdemli K,Akcay A,Guz G

更新日期：2014-06-01 00:00:00

abstract：AIM:When peritoneal fibrosis (PF) causes ultrafiltration failure in peritoneal dialysis (PD) patients, PD has to be discontinued. Currently, there is no effective way to relieve PF. In this study, we aimed to determine whether miR-15a-5p is involved in PF and to determine the underlying mechanism. METHODS:Six normal r...

journal_title：Renal failure

authors： He Q,Wen L,Wang L,Zhang Y,Yu W,Zhang F,Zhang W,Xiao J,Wen X,Zhao Z

更新日期：2020-11-01 00:00:00