Abstract:
:A series of lipoproteins was detected in the membrane fraction of Yersinia enterocolitica W227, a typical strain from serotype O:9. At least two of them, YlpA and YlpB, are encoded by the pYV plasmid. The sequence of ylpA reveals the presence of a typical lipoprotein signal peptide. The mature YlpA protein would be 223 residues long with a calculated molecular weight of 23798 for the proteic moiety of the molecule. YlpA shares 88% identical residues with the TraT protein encoded by plasmid pED208, 80% identity with TraT proteins encoded by plasmids R100 and F, and 77% identity with the TraT protein encoded by the virulence plasmid of Salmonella typhimurium. The ylpA gene hybridized with the pYV plasmid of Yersinia pseudotuberculosis, suggesting that this gene is conserved among Yersinia spp. The production of YlpA is controlled by virF and only occurs at 37 degrees C in the absence of Ca2+ ions. This co-regulation with the yop genes suggests that ylpA is a virulence determinant. However, mutations in ylpA clearly affect neither the resistance to human serum nor the virulence for intravenously inoculated mice.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
China B,Michiels T,Cornelis GRdoi
10.1111/j.1365-2958.1990.tb02070.xsubject
Has Abstractpub_date
1990-09-01 00:00:00pages
1585-93issue
9eissn
0950-382Xissn
1365-2958journal_volume
4pub_type
杂志文章abstract::GPI-anchoring is a universal and critical post-translational protein modification in eukaryotes. In fungi, many cell wall proteins are GPI-anchored, and disruption of GPI-anchored proteins impairs cell wall integrity. After being synthesized and attached to target proteins, GPI anchors undergo modification on lipid mo...
journal_title:Molecular microbiology
pub_type: 杂志文章
doi:10.1111/mmi.12626
更新日期:2014-06-01 00:00:00
abstract::Like other bacterial species, Mycobacterium tuberculosis has multiple sigma (sigma) factors encoded in its genome. In previously published work, we and others have shown that mutations in some of these transcriptional activators render M. tuberculosis sensitive to various environmental stresses and, in some cases, cau...
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doi:10.1046/j.1365-2958.2002.03005.x
更新日期:2002-07-01 00:00:00
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更新日期:2003-04-01 00:00:00
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doi:10.1111/mmi.12666
更新日期:2014-07-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
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更新日期:1994-03-01 00:00:00
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pub_type: 评论,杂志文章
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更新日期:2011-05-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
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更新日期:1994-11-01 00:00:00
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更新日期:2010-01-01 00:00:00
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更新日期:1996-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2004-09-01 00:00:00
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更新日期:2013-02-01 00:00:00
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更新日期:2009-06-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 评论,杂志文章
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更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
doi:10.1111/j.1365-2958.1992.tb01520.x
更新日期:1992-03-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
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更新日期:1994-09-01 00:00:00
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journal_title:Molecular microbiology
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更新日期:2000-08-01 00:00:00
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更新日期:2017-03-01 00:00:00
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journal_title:Molecular microbiology
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更新日期:2012-01-01 00:00:00
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更新日期:2003-03-01 00:00:00
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更新日期:2008-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:1989-05-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
doi:10.1111/mmi.12987
更新日期:2015-06-01 00:00:00
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更新日期:2002-12-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
doi:10.1111/mmi.12018
更新日期:2012-11-01 00:00:00